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The map label for this gene is ybhO [H]

Identifier: 73540150

GI number: 73540150

Start: 487422

End: 488750

Strand: Direct

Name: ybhO [H]

Synonym: Reut_A0444

Alternate gene names: 73540150

Gene position: 487422-488750 (Clockwise)

Preceding gene: 73540148

Following gene: 73540151

Centisome position: 12.8

GC content: 68.25

Gene sequence:

>1329_bases
ATGTCACGGATATCCGACACCGACCCACCGAATGCCGCACGATCCAACGGCGCGGCGCATGTTGCGGCGCGGGATGACAG
CGCCGGTCCCGCAGCACGCGCGGGGCGGCGGCGTCTGCTGCGCTGGGCCGGACGGCACGGCAAGCCGGTCGGCGGCAATC
AGGTAAGGCTGCTGTGCGGCGGGCGCGACTTCTTCCCAGCGCTGATCGAGGCGATCGACGCGGCGGTTCTCCAGGTCATC
ATTGAAACCTACATCTACGCCGACGACGACGTCGGGCGCGCCGTCAGCGATGCGCTGATCCGGGCCGCGGCGCGTGGCGT
AGCCGTGCGGCTGACCGTGGACGGTTTCGGTGCCGGCGACATGTCTGCCGAACTCATGCAGCGCCTGCGCGACGCGGGCG
TGCAGCTGCGTGTCTACCGCGTGATGCGCGGCTTCCGGCTGGCGCGCAGGCACCTGCGCCGCCTGCACCGCAAGCTTGCC
GTGGTCGACCGGCGCGTAGCGTTCGTAGGCGGCATCAACATCATCGACGACTACAATCACGGCCCGTTCGAGCAGGAGGG
ACTCGGGGCACGCTACGACTTCGCCGTGGAAGTGCGCGGCCCGCTGGTCGACCGCATTGCGCTGACGGCGGAGCGCCTCT
GGTGGCGGCTGTCGCTGCGCGCCGAACTGCATGACGTTGGTTTGGCGGGCGCGGCAGCGGGATACCCGCTTGTGACCGAC
CTGCCGCCGCGGCGCGATACGGAAGGCGGCATGCGGGCGGCGCTTCTCCTCCGGGACAACTTGCGCAACCGCCGCACCAT
CGAGCGCGAATATCTGCACGCGCTGGGTGCTGCGCGCGACGACGTGATTCTCGCCAACGCGTATTTCCTGCCGGGCCACA
AGATGCGGCGCGCGCTGCTGGCCTGCCGCAAGCGCGGCGTGCGGGTACGATTGTTGTTGCAGGGTCGCGTCGAATACCGG
CTGCAGCATTTCGCCACGCACGCGCTGTACGCGAGCTTGCTTGATGCCGGCATCGAGATCTACGAGTACGCGCAGAGCTT
CCTGCACGCCAAGGTCGGTGTGGTGGATGAATCCTGGGCCACGGTCGGATCCAGCAATATGGATCCGTTCAGCCTGCTGC
TCGCACGCGAGGCCAACGTCTGCGTCTATGATCCTGCCTTCGCCGCCGTCCTGCGCACGCAGCTGGAGCGCGCCATTGCC
GAGCGCAGCGTGCGCGTTATGCCGGAGGCGCATGCCCGGCGCTCGGCGGTGCACCGTGTGGCGAACTGGGCCGCCTACAT
GGTGTTGCGTCTTGGCGTCGTTATTGCCGGTGTGACGGGGCGCTATTGA

Upstream 100 bases:

>100_bases
AATACCTTCACAGTGCTATCCCTTGGTGCATGAGTGATCGACGATAGCAGAGATGCACCGCCCCATGTGCAGATGGCGGC
GTGTGTCCCATAATCGCATC

Downstream 100 bases:

>100_bases
AACGGCACGCCGATATTGCCCCGCAGCATGACAGGGGCTGCGCGGCTGATGGCATCAGGCTGCGTGTTGATGTTGCAACG
CAGTCGGTTTAGAAACGTGG

Product: phospholipase D/transphosphatidylase

Products: NA

Alternate protein names: CL synthase [H]

Number of amino acids: Translated: 442; Mature: 441

Protein sequence:

>442_residues
MSRISDTDPPNAARSNGAAHVAARDDSAGPAARAGRRRLLRWAGRHGKPVGGNQVRLLCGGRDFFPALIEAIDAAVLQVI
IETYIYADDDVGRAVSDALIRAAARGVAVRLTVDGFGAGDMSAELMQRLRDAGVQLRVYRVMRGFRLARRHLRRLHRKLA
VVDRRVAFVGGINIIDDYNHGPFEQEGLGARYDFAVEVRGPLVDRIALTAERLWWRLSLRAELHDVGLAGAAAGYPLVTD
LPPRRDTEGGMRAALLLRDNLRNRRTIEREYLHALGAARDDVILANAYFLPGHKMRRALLACRKRGVRVRLLLQGRVEYR
LQHFATHALYASLLDAGIEIYEYAQSFLHAKVGVVDESWATVGSSNMDPFSLLLAREANVCVYDPAFAAVLRTQLERAIA
ERSVRVMPEAHARRSAVHRVANWAAYMVLRLGVVIAGVTGRY

Sequences:

>Translated_442_residues
MSRISDTDPPNAARSNGAAHVAARDDSAGPAARAGRRRLLRWAGRHGKPVGGNQVRLLCGGRDFFPALIEAIDAAVLQVI
IETYIYADDDVGRAVSDALIRAAARGVAVRLTVDGFGAGDMSAELMQRLRDAGVQLRVYRVMRGFRLARRHLRRLHRKLA
VVDRRVAFVGGINIIDDYNHGPFEQEGLGARYDFAVEVRGPLVDRIALTAERLWWRLSLRAELHDVGLAGAAAGYPLVTD
LPPRRDTEGGMRAALLLRDNLRNRRTIEREYLHALGAARDDVILANAYFLPGHKMRRALLACRKRGVRVRLLLQGRVEYR
LQHFATHALYASLLDAGIEIYEYAQSFLHAKVGVVDESWATVGSSNMDPFSLLLAREANVCVYDPAFAAVLRTQLERAIA
ERSVRVMPEAHARRSAVHRVANWAAYMVLRLGVVIAGVTGRY
>Mature_441_residues
SRISDTDPPNAARSNGAAHVAARDDSAGPAARAGRRRLLRWAGRHGKPVGGNQVRLLCGGRDFFPALIEAIDAAVLQVII
ETYIYADDDVGRAVSDALIRAAARGVAVRLTVDGFGAGDMSAELMQRLRDAGVQLRVYRVMRGFRLARRHLRRLHRKLAV
VDRRVAFVGGINIIDDYNHGPFEQEGLGARYDFAVEVRGPLVDRIALTAERLWWRLSLRAELHDVGLAGAAAGYPLVTDL
PPRRDTEGGMRAALLLRDNLRNRRTIEREYLHALGAARDDVILANAYFLPGHKMRRALLACRKRGVRVRLLLQGRVEYRL
QHFATHALYASLLDAGIEIYEYAQSFLHAKVGVVDESWATVGSSNMDPFSLLLAREANVCVYDPAFAAVLRTQLERAIAE
RSVRVMPEAHARRSAVHRVANWAAYMVLRLGVVIAGVTGRY

Specific function: Catalyzes, in vitro, the phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol [H]

COG id: COG1502

COG function: function code I; Phosphatidylserine/phosphatidylglycerophosphate/cardiolipin synthases and related enzymes

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 PLD phosphodiesterase domains [H]

Homologues:

Organism=Escherichia coli, GI1787007, Length=396, Percent_Identity=35.8585858585859, Blast_Score=229, Evalue=3e-61,
Organism=Escherichia coli, GI1787502, Length=384, Percent_Identity=26.8229166666667, Blast_Score=116, Evalue=3e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001736 [H]

Pfam domain/function: PF00614 PLDc [H]

EC number: 2.7.8.-

Molecular weight: Translated: 48986; Mature: 48855

Theoretical pI: Translated: 10.69; Mature: 10.69

Prosite motif: PS50035 PLD

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSRISDTDPPNAARSNGAAHVAARDDSAGPAARAGRRRLLRWAGRHGKPVGGNQVRLLCG
CCCCCCCCCCCCHHCCCCEEEEECCCCCCHHHHHHHHHHHHHHCCCCCCCCCCEEEEEEC
GRDFFPALIEAIDAAVLQVIIETYIYADDDVGRAVSDALIRAAARGVAVRLTVDGFGAGD
CCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCEEEEEEECCCCCCC
MSAELMQRLRDAGVQLRVYRVMRGFRLARRHLRRLHRKLAVVDRRVAFVGGINIIDDYNH
HHHHHHHHHHHCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCC
GPFEQEGLGARYDFAVEVRGPLVDRIALTAERLWWRLSLRAELHDVGLAGAAAGYPLVTD
CCCCCCCCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCC
LPPRRDTEGGMRAALLLRDNLRNRRTIEREYLHALGAARDDVILANAYFLPGHKMRRALL
CCCCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCEEEEEEEECCCHHHHHHHH
ACRKRGVRVRLLLQGRVEYRLQHFATHALYASLLDAGIEIYEYAQSFLHAKVGVVDESWA
HHHHCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHH
TVGSSNMDPFSLLLAREANVCVYDPAFAAVLRTQLERAIAERSVRVMPEAHARRSAVHRV
HCCCCCCCHHHHHHCCCCCEEEECHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
ANWAAYMVLRLGVVIAGVTGRY
HHHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure 
SRISDTDPPNAARSNGAAHVAARDDSAGPAARAGRRRLLRWAGRHGKPVGGNQVRLLCG
CCCCCCCCCCCHHCCCCEEEEECCCCCCHHHHHHHHHHHHHHCCCCCCCCCCEEEEEEC
GRDFFPALIEAIDAAVLQVIIETYIYADDDVGRAVSDALIRAAARGVAVRLTVDGFGAGD
CCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCEEEEEEECCCCCCC
MSAELMQRLRDAGVQLRVYRVMRGFRLARRHLRRLHRKLAVVDRRVAFVGGINIIDDYNH
HHHHHHHHHHHCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCC
GPFEQEGLGARYDFAVEVRGPLVDRIALTAERLWWRLSLRAELHDVGLAGAAAGYPLVTD
CCCCCCCCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCC
LPPRRDTEGGMRAALLLRDNLRNRRTIEREYLHALGAARDDVILANAYFLPGHKMRRALL
CCCCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCEEEEEEEECCCHHHHHHHH
ACRKRGVRVRLLLQGRVEYRLQHFATHALYASLLDAGIEIYEYAQSFLHAKVGVVDESWA
HHHHCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHH
TVGSSNMDPFSLLLAREANVCVYDPAFAAVLRTQLERAIAERSVRVMPEAHARRSAVHRV
HCCCCCCCHHHHHHCCCCCEEEECHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
ANWAAYMVLRLGVVIAGVTGRY
HHHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11677608; 12644504 [H]