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The map label for this gene is cutS [H]

Identifier: 73540131

GI number: 73540131

Start: 466050

End: 466559

Strand: Reverse

Name: cutS [H]

Synonym: Reut_A0425

Alternate gene names: 73540131

Gene position: 466559-466050 (Counterclockwise)

Preceding gene: 73540149

Following gene: 73540130

Centisome position: 12.26

GC content: 66.67

Gene sequence:

>510_bases
ATGCCGATTCCGATCCGCCTGACGGTCAATGGCAAGGCCGTTGACGCTCAGGTAGAACCCAACACCCTACTCGTCCAGTT
CCTCCGCGAACAGCTCCGGCTGACCGGCACGCATGTCGGCTGCGATACCGCGCAGTGCGGCGCCTGCACGATCCACCTGG
ACGGGCGCGCGGTCAAGTCCTGCAATATCCTCGCCGTGCAGGCCGATGGCGCCGAGGTTACGACCATTGAGGGCCTCGCA
GGCATACGCGTGGGCAACGGGTCTCCGGCCATGCACCCGATGCAGGAAGCCTTCCGCGAATGCCACGGCCTGCAATGCGG
CTTCTGCACGCCCGGCATGGTCATGGCAGCCACGGCGCTCGTGAACGCGCGGCCGGATGCCGATGCCACCACCATCCGCC
AGCAACTCGAAGGCAACCTGTGCCGCTGCACCGGTTATCACAACATCGTCAAGGCCGTGCAGCAGGGCCAGGCCGCCATG
CTCGCGGGCACCGCCGCGAGCGCCGAGTAA

Upstream 100 bases:

>100_bases
AGCCGTAGCAAACGGCAGTACCGCGTCGTGGCCAGTCCCGCGCTGTTCTTTCGGGTTCCTGGGAATTGGTCATGCGCTTC
CACCCCTCATGGAGACAAGC

Downstream 100 bases:

>100_bases
GGGAGGCCAGCCATGAACGCACCCGAATCGCAGAAATTCGTCGGCACGGCGGTCAAGCGCAAGGAAGACTTCCGCTTCCT
GACCGGCAACGGCCAGTACA

Product: ferredoxin:(2Fe-2S)-binding

Products: NA

Alternate protein names: CO dehydrogenase subunit S; CO-DH S [H]

Number of amino acids: Translated: 169; Mature: 168

Protein sequence:

>169_residues
MPIPIRLTVNGKAVDAQVEPNTLLVQFLREQLRLTGTHVGCDTAQCGACTIHLDGRAVKSCNILAVQADGAEVTTIEGLA
GIRVGNGSPAMHPMQEAFRECHGLQCGFCTPGMVMAATALVNARPDADATTIRQQLEGNLCRCTGYHNIVKAVQQGQAAM
LAGTAASAE

Sequences:

>Translated_169_residues
MPIPIRLTVNGKAVDAQVEPNTLLVQFLREQLRLTGTHVGCDTAQCGACTIHLDGRAVKSCNILAVQADGAEVTTIEGLA
GIRVGNGSPAMHPMQEAFRECHGLQCGFCTPGMVMAATALVNARPDADATTIRQQLEGNLCRCTGYHNIVKAVQQGQAAM
LAGTAASAE
>Mature_168_residues
PIPIRLTVNGKAVDAQVEPNTLLVQFLREQLRLTGTHVGCDTAQCGACTIHLDGRAVKSCNILAVQADGAEVTTIEGLAG
IRVGNGSPAMHPMQEAFRECHGLQCGFCTPGMVMAATALVNARPDADATTIRQQLEGNLCRCTGYHNIVKAVQQGQAAML
AGTAASAE

Specific function: Catalyzes the oxidation of carbon monoxide to carbon dioxide [H]

COG id: COG2080

COG function: function code C; Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS/CutS homologs

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 2Fe-2S ferredoxin-type domain [H]

Homologues:

Organism=Homo sapiens, GI71773480, Length=157, Percent_Identity=38.8535031847134, Blast_Score=99, Evalue=2e-21,
Organism=Homo sapiens, GI91823271, Length=157, Percent_Identity=37.5796178343949, Blast_Score=92, Evalue=3e-19,
Organism=Escherichia coli, GI1786480, Length=169, Percent_Identity=41.4201183431953, Blast_Score=130, Evalue=6e-32,
Organism=Escherichia coli, GI1789232, Length=154, Percent_Identity=44.1558441558442, Blast_Score=114, Evalue=4e-27,
Organism=Caenorhabditis elegans, GI17540638, Length=153, Percent_Identity=43.1372549019608, Blast_Score=127, Evalue=2e-30,
Organism=Caenorhabditis elegans, GI32566215, Length=165, Percent_Identity=36.969696969697, Blast_Score=109, Evalue=6e-25,
Organism=Caenorhabditis elegans, GI17539860, Length=163, Percent_Identity=34.9693251533742, Blast_Score=106, Evalue=5e-24,
Organism=Drosophila melanogaster, GI17737937, Length=159, Percent_Identity=40.251572327044, Blast_Score=110, Evalue=3e-25,
Organism=Drosophila melanogaster, GI24647197, Length=164, Percent_Identity=36.5853658536585, Blast_Score=96, Evalue=8e-21,
Organism=Drosophila melanogaster, GI24647195, Length=164, Percent_Identity=36.5853658536585, Blast_Score=96, Evalue=9e-21,
Organism=Drosophila melanogaster, GI24647193, Length=167, Percent_Identity=35.3293413173653, Blast_Score=87, Evalue=6e-18,
Organism=Drosophila melanogaster, GI24647201, Length=156, Percent_Identity=35.2564102564103, Blast_Score=86, Evalue=8e-18,
Organism=Drosophila melanogaster, GI24647199, Length=157, Percent_Identity=34.3949044585987, Blast_Score=86, Evalue=1e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002888
- InterPro:   IPR012675
- InterPro:   IPR001041 [H]

Pfam domain/function: PF00111 Fer2; PF01799 Fer2_2 [H]

EC number: =1.2.99.2 [H]

Molecular weight: Translated: 17685; Mature: 17553

Theoretical pI: Translated: 6.64; Mature: 6.64

Prosite motif: PS00197 2FE2S_FER_1 ; PS51085 2FE2S_FER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

5.3 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
8.9 %Cys+Met (Translated Protein)
5.4 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
8.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPIPIRLTVNGKAVDAQVEPNTLLVQFLREQLRLTGTHVGCDTAQCGACTIHLDGRAVKS
CCEEEEEEECCCEEEEEECCHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEECCCEECC
CNILAVQADGAEVTTIEGLAGIRVGNGSPAMHPMQEAFRECHGLQCGFCTPGMVMAATAL
CEEEEEECCCCEEEEECCCEEEEECCCCCCCCHHHHHHHHHCCCCCCCCCCCHHHHHHHH
VNARPDADATTIRQQLEGNLCRCTGYHNIVKAVQQGQAAMLAGTAASAE
HCCCCCCHHHHHHHHHCCCEEEECCHHHHHHHHHCCCEEEEECCCCCCC
>Mature Secondary Structure 
PIPIRLTVNGKAVDAQVEPNTLLVQFLREQLRLTGTHVGCDTAQCGACTIHLDGRAVKS
CEEEEEEECCCEEEEEECCHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEECCCEECC
CNILAVQADGAEVTTIEGLAGIRVGNGSPAMHPMQEAFRECHGLQCGFCTPGMVMAATAL
CEEEEEECCCCEEEEECCCEEEEECCCCCCCCHHHHHHHHHCCCCCCCCCCCHHHHHHHH
VNARPDADATTIRQQLEGNLCRCTGYHNIVKAVQQGQAAMLAGTAASAE
HCCCCCCHHHHHHHHHCCCEEEECCHHHHHHHHHCCCEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10482497; 2818128; 10966817; 11076018 [H]