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The map label for this gene is cutL [H]

Identifier: 73540130

GI number: 73540130

Start: 463662

End: 466037

Strand: Reverse

Name: cutL [H]

Synonym: Reut_A0424

Alternate gene names: 73540130

Gene position: 466037-463662 (Counterclockwise)

Preceding gene: 73540131

Following gene: 73540129

Centisome position: 12.24

GC content: 66.33

Gene sequence:

>2376_bases
ATGAACGCACCCGAATCGCAGAAATTCGTCGGCACGGCGGTCAAGCGCAAGGAAGACTTCCGCTTCCTGACCGGCAACGG
CCAGTACACCGACGACATCGTGCTTCCGCAGCAGAGCTACGGCTACTTCCTGCGCTCGCCACACGCCCATGCGCGCATCA
AGTCGATCGACAAGAGCGCGGCGCTGGATGCGCCCGGCGTGATCGCCGTATTGACCGGCGAGGACATGGCCGCCGACAAA
GTCGGTGGTTTGCCCTGCGGCTGGCTGATCCACAGCATCGACGGCACGCCGATGAAGGAGCCGCCCCACCCCGTCATCGC
GCAAGGCAAGGTGCGCCATGTCGGCGACCAGGTGGCGCTGGTGGTGGCCGAGACGCTGATGCAGGCGAAGGACGCCGCCG
AGAAGATCGACGTCCAATACGAAGAACTGCCTGCCGTCGTCAACGCGGCCGATGCCGCCGCGGCCACGACGCTCGTACAT
GACGACGTGCCAGCCAACACCTGCTACACGTGGGGCCACGGCGACAAGGCCGCAACCGACGCCGCGTTCGCCAAGGCCGC
GCACGTGACCACGCTGGATATCGTGAACAACCGGCTGATCCCCAACGCGATCGAACCGCGCGCGGTCAACGCGAGCTACA
CGCGCCAGGACGACAGCTACACGGTCTACGTGGCCAACCAGAACCCGCATGTCGAACGCCTGCTGATGGGCGCCTTCGTG
CTGGGCCTGCCGGAATCGCGGCTGCGCATCATCGCGCCGGATGTTGGCGGCGGCTTCGGCTCGAAGATCTTCCTCTATGC
GGAGGACGTGGCGCTGACCTGGGCCTCGAAGAAGGTCGGCCGGCCGATCAAGTGGACGGCCGAGCGGTCGGAATCATTCC
TGACCGATGCCCATGGCCGCGACCACGTGACCAAGGCCGAGCTCGCGCTCGACAGCGACGGCAAGTTCCTGGCCATGCGC
GTGCACACCACGGCCAACATGGGCGCGTACCTGTCGACATTCGCGAGCAGCGTGCCGACCATCCTTTACGCGACGCTGCT
GGCCGGACAGTACGCCACGCCGGCGATCTACGCCGAAGTGAAGGCGGTGTTCACCAACACCGCGCCCGTGGACGCCTACC
GTGGCGCGGGCCGCCCCGAAGCGACATACGTAGTCGAACGCCTGGTGGAAACCGCCGCGCACGAGATGAAGATGGACCCG
GCCGAACTGCGCCGCAAGAACTTCATCCGCGATTTCCCGTACGCGACGCCGGTCGGCCTGACCTACGACACTGGCGACTA
CGAGCCCTGCCTCGCACGTGCGCAGGAACTCGCCGACGTGAAGGGCTTCCCGGCGCGCCGCGACGAAGCTAAGCAGCGCG
GCAAGCTGCGCGGCCTCGGCTACTCGTGCTACATCGAAGCGTGCGGGCTGGCGCCGTCGAACATTGCCGGCGCACTGGGC
GCGCGCGCGGGCCTGTTCGAAGTCGGCGAGATCCGCGTGCACCCGACCGGCTCCGTCACGGTATTCACCGGCTCGCACAG
CCATGGGCAAGGCCACGAAACCACGTTCGCGCAGATCGTGGCTGACCGGCTTGGCATCGCGCTGGAATCCGTCGAGATCG
TGCACGGCGACACCGGCCGCGTGCCGTTCGGCATGGGCACCTACGGCTCGCGCTCGCTCGCGGTGGGCGGTTCGGCGATC
ATGAAGGCGCTTGACAAGATCGAGGCCAAGGCCAAGAAGATCGCCGCGCACTTGCTCGAAGCGTCCGATGCCGATGTCGA
GTTCAGCAACGGCGTGTTCCGCGTGGCCGGCACCGACCGCACCAAGACCTTTGGCGAAGTCGCGCTGACCGCCTATGTGC
CGCATAACTACCCGCTCGACAAGCTCGAGCCCGGGCTGAATGAAAACGCGTTCTACGATCCGACCAACTTCACGTACCCT
TCGGGCGCCTACGTATGCGAGGTCGAAGTCGACCCGGAAACCGGCGAGTCGCAAGTCGTGAAGTTCACCGCAGTCGACGA
CTTCGGCAACATCGTCAACCCGATGATCGTTGAGGGCCAGGTGCACGGCGGCATCGGCCAGGGCCTCGGCCAGGCCATGC
TGGAACAGTGCATCTACGACAGCGATAGCGGCCAGTTGCTGACCGGCTCGTACATGGACTACGCGATGGCGCGCGCGGGC
GACCTGCCCGACTTCACCGTGGAAACCGCCAAGGGCACGCCGTGCACGCACAACCCGCTCGGCGTGAAGGGTTGCGGCGA
AGCCGGCGCCATCGGCTCGCCGCCCGCGTTCATCAACGCGCTGGTCGATGCGCTATCGCCACTCGGCGTGAAAGACCTGC
AAATGCCAGCCACGCCGCATCGCGTGTGGCAGGCCATCCAGGCCGCCAAGCCCTGA

Upstream 100 bases:

>100_bases
CCGCTGCACCGGTTATCACAACATCGTCAAGGCCGTGCAGCAGGGCCAGGCCGCCATGCTCGCGGGCACCGCCGCGAGCG
CCGAGTAAGGGAGGCCAGCC

Downstream 100 bases:

>100_bases
GTCCGCCGACGAACCACAAAGGAAACCGACATGTACGCATTCCAGTTTGAACGTGCAGCGGATGCCAAGGCGGCCGTCGC
GAAGCTCAAGGCAGACCCCG

Product: xanthine dehydrogenase, molybdenum binding subunit apoprotein

Products: NA

Alternate protein names: CO dehydrogenase subunit L; CO-DH L [H]

Number of amino acids: Translated: 791; Mature: 791

Protein sequence:

>791_residues
MNAPESQKFVGTAVKRKEDFRFLTGNGQYTDDIVLPQQSYGYFLRSPHAHARIKSIDKSAALDAPGVIAVLTGEDMAADK
VGGLPCGWLIHSIDGTPMKEPPHPVIAQGKVRHVGDQVALVVAETLMQAKDAAEKIDVQYEELPAVVNAADAAAATTLVH
DDVPANTCYTWGHGDKAATDAAFAKAAHVTTLDIVNNRLIPNAIEPRAVNASYTRQDDSYTVYVANQNPHVERLLMGAFV
LGLPESRLRIIAPDVGGGFGSKIFLYAEDVALTWASKKVGRPIKWTAERSESFLTDAHGRDHVTKAELALDSDGKFLAMR
VHTTANMGAYLSTFASSVPTILYATLLAGQYATPAIYAEVKAVFTNTAPVDAYRGAGRPEATYVVERLVETAAHEMKMDP
AELRRKNFIRDFPYATPVGLTYDTGDYEPCLARAQELADVKGFPARRDEAKQRGKLRGLGYSCYIEACGLAPSNIAGALG
ARAGLFEVGEIRVHPTGSVTVFTGSHSHGQGHETTFAQIVADRLGIALESVEIVHGDTGRVPFGMGTYGSRSLAVGGSAI
MKALDKIEAKAKKIAAHLLEASDADVEFSNGVFRVAGTDRTKTFGEVALTAYVPHNYPLDKLEPGLNENAFYDPTNFTYP
SGAYVCEVEVDPETGESQVVKFTAVDDFGNIVNPMIVEGQVHGGIGQGLGQAMLEQCIYDSDSGQLLTGSYMDYAMARAG
DLPDFTVETAKGTPCTHNPLGVKGCGEAGAIGSPPAFINALVDALSPLGVKDLQMPATPHRVWQAIQAAKP

Sequences:

>Translated_791_residues
MNAPESQKFVGTAVKRKEDFRFLTGNGQYTDDIVLPQQSYGYFLRSPHAHARIKSIDKSAALDAPGVIAVLTGEDMAADK
VGGLPCGWLIHSIDGTPMKEPPHPVIAQGKVRHVGDQVALVVAETLMQAKDAAEKIDVQYEELPAVVNAADAAAATTLVH
DDVPANTCYTWGHGDKAATDAAFAKAAHVTTLDIVNNRLIPNAIEPRAVNASYTRQDDSYTVYVANQNPHVERLLMGAFV
LGLPESRLRIIAPDVGGGFGSKIFLYAEDVALTWASKKVGRPIKWTAERSESFLTDAHGRDHVTKAELALDSDGKFLAMR
VHTTANMGAYLSTFASSVPTILYATLLAGQYATPAIYAEVKAVFTNTAPVDAYRGAGRPEATYVVERLVETAAHEMKMDP
AELRRKNFIRDFPYATPVGLTYDTGDYEPCLARAQELADVKGFPARRDEAKQRGKLRGLGYSCYIEACGLAPSNIAGALG
ARAGLFEVGEIRVHPTGSVTVFTGSHSHGQGHETTFAQIVADRLGIALESVEIVHGDTGRVPFGMGTYGSRSLAVGGSAI
MKALDKIEAKAKKIAAHLLEASDADVEFSNGVFRVAGTDRTKTFGEVALTAYVPHNYPLDKLEPGLNENAFYDPTNFTYP
SGAYVCEVEVDPETGESQVVKFTAVDDFGNIVNPMIVEGQVHGGIGQGLGQAMLEQCIYDSDSGQLLTGSYMDYAMARAG
DLPDFTVETAKGTPCTHNPLGVKGCGEAGAIGSPPAFINALVDALSPLGVKDLQMPATPHRVWQAIQAAKP
>Mature_791_residues
MNAPESQKFVGTAVKRKEDFRFLTGNGQYTDDIVLPQQSYGYFLRSPHAHARIKSIDKSAALDAPGVIAVLTGEDMAADK
VGGLPCGWLIHSIDGTPMKEPPHPVIAQGKVRHVGDQVALVVAETLMQAKDAAEKIDVQYEELPAVVNAADAAAATTLVH
DDVPANTCYTWGHGDKAATDAAFAKAAHVTTLDIVNNRLIPNAIEPRAVNASYTRQDDSYTVYVANQNPHVERLLMGAFV
LGLPESRLRIIAPDVGGGFGSKIFLYAEDVALTWASKKVGRPIKWTAERSESFLTDAHGRDHVTKAELALDSDGKFLAMR
VHTTANMGAYLSTFASSVPTILYATLLAGQYATPAIYAEVKAVFTNTAPVDAYRGAGRPEATYVVERLVETAAHEMKMDP
AELRRKNFIRDFPYATPVGLTYDTGDYEPCLARAQELADVKGFPARRDEAKQRGKLRGLGYSCYIEACGLAPSNIAGALG
ARAGLFEVGEIRVHPTGSVTVFTGSHSHGQGHETTFAQIVADRLGIALESVEIVHGDTGRVPFGMGTYGSRSLAVGGSAI
MKALDKIEAKAKKIAAHLLEASDADVEFSNGVFRVAGTDRTKTFGEVALTAYVPHNYPLDKLEPGLNENAFYDPTNFTYP
SGAYVCEVEVDPETGESQVVKFTAVDDFGNIVNPMIVEGQVHGGIGQGLGQAMLEQCIYDSDSGQLLTGSYMDYAMARAG
DLPDFTVETAKGTPCTHNPLGVKGCGEAGAIGSPPAFINALVDALSPLGVKDLQMPATPHRVWQAIQAAKP

Specific function: Catalyzes the oxidation of carbon monoxide to carbon dioxide [H]

COG id: COG1529

COG function: function code C; Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL/CutL homologs

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI91823271, Length=801, Percent_Identity=26.2172284644195, Blast_Score=161, Evalue=2e-39,
Organism=Homo sapiens, GI71773480, Length=804, Percent_Identity=23.8805970149254, Blast_Score=161, Evalue=2e-39,
Organism=Escherichia coli, GI1789230, Length=782, Percent_Identity=27.4936061381074, Blast_Score=243, Evalue=5e-65,
Organism=Escherichia coli, GI1789246, Length=835, Percent_Identity=26.2275449101796, Blast_Score=204, Evalue=3e-53,
Organism=Escherichia coli, GI1786478, Length=735, Percent_Identity=26.3945578231293, Blast_Score=140, Evalue=3e-34,
Organism=Caenorhabditis elegans, GI17540638, Length=815, Percent_Identity=25.398773006135, Blast_Score=158, Evalue=1e-38,
Organism=Caenorhabditis elegans, GI17539860, Length=805, Percent_Identity=22.9813664596273, Blast_Score=141, Evalue=2e-33,
Organism=Caenorhabditis elegans, GI32566215, Length=809, Percent_Identity=22.7441285537701, Blast_Score=112, Evalue=7e-25,
Organism=Drosophila melanogaster, GI17737937, Length=759, Percent_Identity=27.0092226613966, Blast_Score=158, Evalue=1e-38,
Organism=Drosophila melanogaster, GI24647193, Length=819, Percent_Identity=23.3211233211233, Blast_Score=100, Evalue=3e-21,
Organism=Drosophila melanogaster, GI24647195, Length=809, Percent_Identity=23.7330037082818, Blast_Score=96, Evalue=7e-20,
Organism=Drosophila melanogaster, GI24647197, Length=828, Percent_Identity=23.4299516908213, Blast_Score=96, Evalue=9e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000674
- InterPro:   IPR008274
- InterPro:   IPR012780 [H]

Pfam domain/function: PF01315 Ald_Xan_dh_C; PF02738 Ald_Xan_dh_C2 [H]

EC number: =1.2.99.2 [H]

Molecular weight: Translated: 84558; Mature: 84558

Theoretical pI: Translated: 5.58; Mature: 5.58

Prosite motif: PS00107 PROTEIN_KINASE_ATP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNAPESQKFVGTAVKRKEDFRFLTGNGQYTDDIVLPQQSYGYFLRSPHAHARIKSIDKSA
CCCCCCHHHHHHHHHCCCCCEEEECCCCCCCCEECCCHHCCCEECCCCHHHHHHHCCHHH
ALDAPGVIAVLTGEDMAADKVGGLPCGWLIHSIDGTPMKEPPHPVIAQGKVRHVGDQVAL
CCCCCCEEEEEECCCCCHHHCCCCCHHHHEECCCCCCCCCCCCCCCCCCCHHHCCHHHHH
VVAETLMQAKDAAEKIDVQYEELPAVVNAADAAAATTLVHDDVPANTCYTWGHGDKAATD
HHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHEEEECCCCCCCEEEECCCCCHHHH
AAFAKAAHVTTLDIVNNRLIPNAIEPRAVNASYTRQDDSYTVYVANQNPHVERLLMGAFV
HHHHHHHHEEEEEHHCCCCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCHHHHHHHHHHH
LGLPESRLRIIAPDVGGGFGSKIFLYAEDVALTWASKKVGRPIKWTAERSESFLTDAHGR
HCCCCCCEEEEECCCCCCCCCEEEEEEECEEEEECHHHCCCCEEEEHHHHHHHHHCCCCC
DHVTKAELALDSDGKFLAMRVHTTANMGAYLSTFASSVPTILYATLLAGQYATPAIYAEV
CCCEEEHEEECCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHH
KAVFTNTAPVDAYRGAGRPEATYVVERLVETAAHEMKMDPAELRRKNFIRDFPYATPVGL
HHHCCCCCCCHHHCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCE
TYDTGDYEPCLARAQELADVKGFPARRDEAKQRGKLRGLGYSCYIEACGLAPSNIAGALG
EECCCCCCHHHHHHHHHHHCCCCCCCCHHHHHCCCCCCCCEEEEEEECCCCCHHHHHHHH
ARAGLFEVGEIRVHPTGSVTVFTGSHSHGQGHETTFAQIVADRLGIALESVEIVHGDTGR
CCCCCEEECEEEECCCCCEEEEECCCCCCCCCHHHHHHHHHHHHCCEEEEEEEEECCCCC
VPFGMGTYGSRSLAVGGSAIMKALDKIEAKAKKIAAHLLEASDADVEFSNGVFRVAGTDR
CCCCCCCCCCCEEECCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCEEEEECCCC
TKTFGEVALTAYVPHNYPLDKLEPGLNENAFYDPTNFTYPSGAYVCEVEVDPETGESQVV
CCCCCEEEEEEEECCCCCHHHCCCCCCCCCEECCCCCCCCCCCEEEEEEECCCCCCCEEE
KFTAVDDFGNIVNPMIVEGQVHGGIGQGLGQAMLEQCIYDSDSGQLLTGSYMDYAMARAG
EEEEECCHHHCCCCEEEEEEECCCHHHHHHHHHHHHHHCCCCCCCEEECHHHHHHHHHCC
DLPDFTVETAKGTPCTHNPLGVKGCGEAGAIGSPPAFINALVDALSPLGVKDLQMPATPH
CCCCCEEECCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCHH
RVWQAIQAAKP
HHHHHHHHCCC
>Mature Secondary Structure
MNAPESQKFVGTAVKRKEDFRFLTGNGQYTDDIVLPQQSYGYFLRSPHAHARIKSIDKSA
CCCCCCHHHHHHHHHCCCCCEEEECCCCCCCCEECCCHHCCCEECCCCHHHHHHHCCHHH
ALDAPGVIAVLTGEDMAADKVGGLPCGWLIHSIDGTPMKEPPHPVIAQGKVRHVGDQVAL
CCCCCCEEEEEECCCCCHHHCCCCCHHHHEECCCCCCCCCCCCCCCCCCCHHHCCHHHHH
VVAETLMQAKDAAEKIDVQYEELPAVVNAADAAAATTLVHDDVPANTCYTWGHGDKAATD
HHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHEEEECCCCCCCEEEECCCCCHHHH
AAFAKAAHVTTLDIVNNRLIPNAIEPRAVNASYTRQDDSYTVYVANQNPHVERLLMGAFV
HHHHHHHHEEEEEHHCCCCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCHHHHHHHHHHH
LGLPESRLRIIAPDVGGGFGSKIFLYAEDVALTWASKKVGRPIKWTAERSESFLTDAHGR
HCCCCCCEEEEECCCCCCCCCEEEEEEECEEEEECHHHCCCCEEEEHHHHHHHHHCCCCC
DHVTKAELALDSDGKFLAMRVHTTANMGAYLSTFASSVPTILYATLLAGQYATPAIYAEV
CCCEEEHEEECCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHH
KAVFTNTAPVDAYRGAGRPEATYVVERLVETAAHEMKMDPAELRRKNFIRDFPYATPVGL
HHHCCCCCCCHHHCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCE
TYDTGDYEPCLARAQELADVKGFPARRDEAKQRGKLRGLGYSCYIEACGLAPSNIAGALG
EECCCCCCHHHHHHHHHHHCCCCCCCCHHHHHCCCCCCCCEEEEEEECCCCCHHHHHHHH
ARAGLFEVGEIRVHPTGSVTVFTGSHSHGQGHETTFAQIVADRLGIALESVEIVHGDTGR
CCCCCEEECEEEECCCCCEEEEECCCCCCCCCHHHHHHHHHHHHCCEEEEEEEEECCCCC
VPFGMGTYGSRSLAVGGSAIMKALDKIEAKAKKIAAHLLEASDADVEFSNGVFRVAGTDR
CCCCCCCCCCCEEECCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCEEEEECCCC
TKTFGEVALTAYVPHNYPLDKLEPGLNENAFYDPTNFTYPSGAYVCEVEVDPETGESQVV
CCCCCEEEEEEEECCCCCHHHCCCCCCCCCEECCCCCCCCCCCEEEEEEECCCCCCCEEE
KFTAVDDFGNIVNPMIVEGQVHGGIGQGLGQAMLEQCIYDSDSGQLLTGSYMDYAMARAG
EEEEECCHHHCCCCEEEEEEECCCHHHHHHHHHHHHHHCCCCCCCEEECHHHHHHHHHCC
DLPDFTVETAKGTPCTHNPLGVKGCGEAGAIGSPPAFINALVDALSPLGVKDLQMPATPH
CCCCCEEECCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCHH
RVWQAIQAAKP
HHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10482497; 2818128; 10966817; 11076018 [H]