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The map label for this gene is aspC [H]

Identifier: 73540111

GI number: 73540111

Start: 442752

End: 443963

Strand: Direct

Name: aspC [H]

Synonym: Reut_A0405

Alternate gene names: 73540111

Gene position: 442752-443963 (Clockwise)

Preceding gene: 73540110

Following gene: 73540117

Centisome position: 11.63

GC content: 67.9

Gene sequence:

>1212_bases
ATGCCAGACAGCCCAAGCCGCCACTCGCCTGATCCGCAACTTCCTCTCGCCCGGGACGCCGTCCACAATCTGCGCGCGTC
GCGCATCCGCGAAGTCGCGAACGCCGGCATCGGCCTGCCTGAGGTGCTGCCGTTCTGGTTCGGCGAATCGGATCAGGTCA
CGCCGGACTTCGTCCGCGACGCCGCGGCGCGTGCGCTGGCGGGTGGCGCCACGTTCTATACGCACAACCTCGGCATCGCG
CCCCTTCGCAGTGCGCTGGCCGACTATGTCGGCGCGCTGCATGGCGCCACGCGCATCGAGAACGTCGCGGTCACGAGTGC
CGGCGTCAACGGCCTGATGCTGGCGGCCCAGCTCATTGCCGGGCCTGGCGATCGCGTGGTGGCGGTCACGCCACTATGGC
CCAACCTGGTGGAGATCCCGAAGATCCTCGGCGCCTCGGTCGAAACCGTTTCGCTCGACTATGGTCCGCACGGGTGGACG
CTCGATGTCGACAAGCTGCTCGCGGCGCTGACGCCGGACACGCGTGCGCTGATGGTCAATTCGCCGAACAACCCGACCGG
CTGGGTGATGTCGCGCGCGGCACAACTTACCGTGCTGGACCACTGCCGCCGGCACGGGATCTGGATCATTGCCGACGAGG
TCTATGAGCGGCTCTACTACGGCGATGAACCCGGTGGGGGCGACAGCCGCACCGCGCCGTCGTTCCTGGACATCGCCTCG
CGCGAGGAGCGCGTCATCTGCGTCAACTCGTTTTCCAAGGCGTGGCTGATGACGGGCTGGCGGCTCGGCTGGATGGTGTT
GCCTTCATCGATGACCGACGATCTCGGCAAGCTGATCGAATACAACACCTCGTGCGCGCCTTCGTTCGTGCAGGAGGCAG
GCGTGGCAGCGGTGCGCGAAGGCGAAGCGTTCACGCGCGACCTCGTCCAGCGGTTGCGCACGGCGCGCGACCACCTCGTG
GATGCGCTGTCCGCCTTGCCCGGTGTGGACGCGCATGCGCCGGAGGGCGCGATGTACGTGTTCTTCCGCCTGTCCGGCGC
CACGGACAGCCTGGCCCTGTGCAAGCAGCTCGTGCGGGAAGCGGGTTTGGGGCTGGCACCGGGCAGCGCATTCGGCGATG
AAGGGGAGGGCTTCGTGCGCTGGTGCTATGCGTGCGACACGGATCGCCTCGATGAAGGCGTGCGGCGCCTGCGCGGGTTC
ATCGGGCGCTGA

Upstream 100 bases:

>100_bases
ACAACACACGATCGCCGGGGCTTTACGGTCCGGCAAGATAGCAACATCCCGGGCGCTTTGCGCTACGCTTGGCATCTCGC
TCGCAACCGCAGGAACGCTC

Downstream 100 bases:

>100_bases
GCCTGCGGACTGTCACTGCACGGCCGGCGTAGAGGGACTTCCTGCGCTGGCCTGCGCCTCCTCCTCCCACCATCCGCCGC
CGAGCGCCTGCAGCAGCGCC

Product: aspartate aminotransferase

Products: NA

Alternate protein names: AspAT; Transaminase A [H]

Number of amino acids: Translated: 403; Mature: 402

Protein sequence:

>403_residues
MPDSPSRHSPDPQLPLARDAVHNLRASRIREVANAGIGLPEVLPFWFGESDQVTPDFVRDAAARALAGGATFYTHNLGIA
PLRSALADYVGALHGATRIENVAVTSAGVNGLMLAAQLIAGPGDRVVAVTPLWPNLVEIPKILGASVETVSLDYGPHGWT
LDVDKLLAALTPDTRALMVNSPNNPTGWVMSRAAQLTVLDHCRRHGIWIIADEVYERLYYGDEPGGGDSRTAPSFLDIAS
REERVICVNSFSKAWLMTGWRLGWMVLPSSMTDDLGKLIEYNTSCAPSFVQEAGVAAVREGEAFTRDLVQRLRTARDHLV
DALSALPGVDAHAPEGAMYVFFRLSGATDSLALCKQLVREAGLGLAPGSAFGDEGEGFVRWCYACDTDRLDEGVRRLRGF
IGR

Sequences:

>Translated_403_residues
MPDSPSRHSPDPQLPLARDAVHNLRASRIREVANAGIGLPEVLPFWFGESDQVTPDFVRDAAARALAGGATFYTHNLGIA
PLRSALADYVGALHGATRIENVAVTSAGVNGLMLAAQLIAGPGDRVVAVTPLWPNLVEIPKILGASVETVSLDYGPHGWT
LDVDKLLAALTPDTRALMVNSPNNPTGWVMSRAAQLTVLDHCRRHGIWIIADEVYERLYYGDEPGGGDSRTAPSFLDIAS
REERVICVNSFSKAWLMTGWRLGWMVLPSSMTDDLGKLIEYNTSCAPSFVQEAGVAAVREGEAFTRDLVQRLRTARDHLV
DALSALPGVDAHAPEGAMYVFFRLSGATDSLALCKQLVREAGLGLAPGSAFGDEGEGFVRWCYACDTDRLDEGVRRLRGF
IGR
>Mature_402_residues
PDSPSRHSPDPQLPLARDAVHNLRASRIREVANAGIGLPEVLPFWFGESDQVTPDFVRDAAARALAGGATFYTHNLGIAP
LRSALADYVGALHGATRIENVAVTSAGVNGLMLAAQLIAGPGDRVVAVTPLWPNLVEIPKILGASVETVSLDYGPHGWTL
DVDKLLAALTPDTRALMVNSPNNPTGWVMSRAAQLTVLDHCRRHGIWIIADEVYERLYYGDEPGGGDSRTAPSFLDIASR
EERVICVNSFSKAWLMTGWRLGWMVLPSSMTDDLGKLIEYNTSCAPSFVQEAGVAAVREGEAFTRDLVQRLRTARDHLVD
ALSALPGVDAHAPEGAMYVFFRLSGATDSLALCKQLVREAGLGLAPGSAFGDEGEGFVRWCYACDTDRLDEGVRRLRGFI
GR

Specific function: Unknown

COG id: COG0436

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI95147551, Length=419, Percent_Identity=26.0143198090692, Blast_Score=135, Evalue=7e-32,
Organism=Homo sapiens, GI169881279, Length=419, Percent_Identity=26.0143198090692, Blast_Score=135, Evalue=7e-32,
Organism=Homo sapiens, GI56713256, Length=396, Percent_Identity=25.2525252525253, Blast_Score=112, Evalue=8e-25,
Organism=Homo sapiens, GI56713254, Length=396, Percent_Identity=25.2525252525253, Blast_Score=111, Evalue=9e-25,
Organism=Homo sapiens, GI4507369, Length=358, Percent_Identity=23.463687150838, Blast_Score=97, Evalue=2e-20,
Organism=Homo sapiens, GI169881281, Length=310, Percent_Identity=24.8387096774194, Blast_Score=96, Evalue=8e-20,
Organism=Homo sapiens, GI19263340, Length=392, Percent_Identity=23.469387755102, Blast_Score=79, Evalue=6e-15,
Organism=Homo sapiens, GI215599424, Length=392, Percent_Identity=23.2142857142857, Blast_Score=79, Evalue=7e-15,
Organism=Escherichia coli, GI1786816, Length=350, Percent_Identity=26, Blast_Score=115, Evalue=4e-27,
Organism=Escherichia coli, GI1788722, Length=370, Percent_Identity=24.5945945945946, Blast_Score=110, Evalue=2e-25,
Organism=Escherichia coli, GI1788627, Length=368, Percent_Identity=25.5434782608696, Blast_Score=103, Evalue=1e-23,
Organism=Escherichia coli, GI1787909, Length=365, Percent_Identity=25.2054794520548, Blast_Score=93, Evalue=3e-20,
Organism=Escherichia coli, GI1787710, Length=405, Percent_Identity=25.4320987654321, Blast_Score=66, Evalue=5e-12,
Organism=Escherichia coli, GI1790797, Length=283, Percent_Identity=24.3816254416961, Blast_Score=65, Evalue=6e-12,
Organism=Caenorhabditis elegans, GI17567663, Length=344, Percent_Identity=25, Blast_Score=113, Evalue=1e-25,
Organism=Caenorhabditis elegans, GI71994476, Length=407, Percent_Identity=23.5872235872236, Blast_Score=85, Evalue=7e-17,
Organism=Caenorhabditis elegans, GI71994472, Length=407, Percent_Identity=23.5872235872236, Blast_Score=85, Evalue=7e-17,
Organism=Caenorhabditis elegans, GI17567369, Length=413, Percent_Identity=20.3389830508475, Blast_Score=83, Evalue=3e-16,
Organism=Saccharomyces cerevisiae, GI6322401, Length=411, Percent_Identity=23.6009732360097, Blast_Score=104, Evalue=3e-23,
Organism=Saccharomyces cerevisiae, GI6320317, Length=359, Percent_Identity=24.7910863509749, Blast_Score=77, Evalue=4e-15,
Organism=Drosophila melanogaster, GI28573069, Length=388, Percent_Identity=24.7422680412371, Blast_Score=100, Evalue=1e-21,
Organism=Drosophila melanogaster, GI24646114, Length=388, Percent_Identity=24.7422680412371, Blast_Score=100, Evalue=1e-21,
Organism=Drosophila melanogaster, GI28573067, Length=388, Percent_Identity=24.7422680412371, Blast_Score=100, Evalue=1e-21,
Organism=Drosophila melanogaster, GI28573065, Length=388, Percent_Identity=24.7422680412371, Blast_Score=100, Evalue=1e-21,
Organism=Drosophila melanogaster, GI18859735, Length=359, Percent_Identity=24.2339832869081, Blast_Score=85, Evalue=8e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001176
- InterPro:   IPR004839
- InterPro:   IPR004838
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: =2.6.1.1 [H]

Molecular weight: Translated: 43503; Mature: 43372

Theoretical pI: Translated: 5.26; Mature: 5.26

Prosite motif: PS00105 AA_TRANSFER_CLASS_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPDSPSRHSPDPQLPLARDAVHNLRASRIREVANAGIGLPEVLPFWFGESDQVTPDFVRD
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHCCCCCCCCHHHHHH
AAARALAGGATFYTHNLGIAPLRSALADYVGALHGATRIENVAVTSAGVNGLMLAAQLIA
HHHHHHHCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCHHHHHHHHHHC
GPGDRVVAVTPLWPNLVEIPKILGASVETVSLDYGPHGWTLDVDKLLAALTPDTRALMVN
CCCCCEEEECCCCCCHHHHHHHHCCCCEEEEEECCCCCCEEEHHHHHHHHCCCCEEEEEE
SPNNPTGWVMSRAAQLTVLDHCRRHGIWIIADEVYERLYYGDEPGGGDSRTAPSFLDIAS
CCCCCHHHHHHHHHHHHHHHHHHHCCEEEEHHHHHHHHHCCCCCCCCCCCCCCHHHHHCC
REERVICVNSFSKAWLMTGWRLGWMVLPSSMTDDLGKLIEYNTSCAPSFVQEAGVAAVRE
CCCEEEEECCCCHHHHHCCCEEEEEECCCHHHHHHHHHHHCCCCCCHHHHHHCCCHHHHC
GEAFTRDLVQRLRTARDHLVDALSALPGVDAHAPEGAMYVFFRLSGATDSLALCKQLVRE
CHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEEECCCCHHHHHHHHHHHH
AGLGLAPGSAFGDEGEGFVRWCYACDTDRLDEGVRRLRGFIGR
CCCCCCCCCCCCCCCCCEEEEEECCCHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
PDSPSRHSPDPQLPLARDAVHNLRASRIREVANAGIGLPEVLPFWFGESDQVTPDFVRD
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHCCCCCCCCHHHHHH
AAARALAGGATFYTHNLGIAPLRSALADYVGALHGATRIENVAVTSAGVNGLMLAAQLIA
HHHHHHHCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCHHHHHHHHHHC
GPGDRVVAVTPLWPNLVEIPKILGASVETVSLDYGPHGWTLDVDKLLAALTPDTRALMVN
CCCCCEEEECCCCCCHHHHHHHHCCCCEEEEEECCCCCCEEEHHHHHHHHCCCCEEEEEE
SPNNPTGWVMSRAAQLTVLDHCRRHGIWIIADEVYERLYYGDEPGGGDSRTAPSFLDIAS
CCCCCHHHHHHHHHHHHHHHHHHHCCEEEEHHHHHHHHHCCCCCCCCCCCCCCHHHHHCC
REERVICVNSFSKAWLMTGWRLGWMVLPSSMTDDLGKLIEYNTSCAPSFVQEAGVAAVRE
CCCEEEEECCCCHHHHHCCCEEEEEECCCHHHHHHHHHHHCCCCCCHHHHHHCCCHHHHC
GEAFTRDLVQRLRTARDHLVDALSALPGVDAHAPEGAMYVFFRLSGATDSLALCKQLVRE
CHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEEECCCCHHHHHHHHHHHH
AGLGLAPGSAFGDEGEGFVRWCYACDTDRLDEGVRRLRGFIGR
CCCCCCCCCCCCCCCCCEEEEEECCCHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9679194 [H]