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The map label for this gene is erg3 [H]

Identifier: 73540093

GI number: 73540093

Start: 424977

End: 425870

Strand: Reverse

Name: erg3 [H]

Synonym: Reut_A0387

Alternate gene names: 73540093

Gene position: 425870-424977 (Counterclockwise)

Preceding gene: 73540100

Following gene: 73540090

Centisome position: 11.19

GC content: 63.53

Gene sequence:

>894_bases
ATGCACAACCTACACAAGATCACCCTCTTCGCCACGGTCTTCGTCGTGGCGGCCTCCATGGTGGAAGCCTTCTTCCTGTC
ACGGAAGGCGCGCCTGCAAGGCAAGACCTACCCCTGGCACGAAATGGGGCTGTCGCTGGCCGACATGCTCGGTCGCAAGC
TGATGGCACTGCTGCCGCTGTCGCTGGCCACGCCGATCTTCGCGTTCGCCTGGGATCACCGGATCAACACTATCCACATC
CACAGCGTGCTGATGGTGCTTCTGCTCTTCATCGGCCAGGAATTCTGCTACTACTGGTACCACCGCGCATCGCACCGCAT
CCGCTTCTTCTGGGCCACGCATGCGGTGCACCACTCGCCGAACGAGCTGACGCTGGGCACGGCCTACCGCCTGGGCCTGA
CCGGCAGGCTCACGGGCACCGCGATGTTCTTCGCGCCGCTGGTCTGGCTCGGTGTTCGCCCCGAAGCCGTGCTGGCCGCG
CTGAGCCTCAACCTGCTCTACCAGTTCTGGCTGCACACCACGTGGATCCCCAAGCTCGGCTGGTTCGAGTACGTGTTCAA
CACCCCGTCGGCGCACCGCGTGCACCATGCCTCGAATGTCGATTACCTCGATGCCAACTACGGCGGCGTGCTGATCCTCT
TCGACCGCCTGTTCGGCACCTATGTGGAAGAGCGTGAAGACGAACCGTGCCGCTTCGGCCTCGTCCACCCGACCACCACG
CATAACCCGATCGTCAACCAGTTCGAACACTGGGTCAGCCTGGGCAAGGACATGATGAAGTCGGGCAGCGTGCTCAATGC
GGTCGGTTATCTGGTGATGCCGCCGGGCTGGAGCCACGACGGCAATGGCGAAACGACGGAGACGCTGCGCAGGCAGGCGG
CGGTGGGGGTGTGA

Upstream 100 bases:

>100_bases
TGCATGGCGCCCGCCGCGGCCGGCCACTACATTTGCCTCACCGACGCGACGGCGGCCCGCTCCGCAAACCAGGCGTCCCA
CCCACTGCACTGGAACGATC

Downstream 100 bases:

>100_bases
GGTAGTCAGCGAAGGGAGCAGTCCGGCGGAAGACTCGGCGGGGCCAGAGAGAACCTGTGGCGCGGCTTTGCCGCGCTTTT
TTTGGTTGTGTCGTCGACAC

Product: hypothetical protein

Products: NA

Alternate protein names: Sterol-C5-desaturase [H]

Number of amino acids: Translated: 297; Mature: 297

Protein sequence:

>297_residues
MHNLHKITLFATVFVVAASMVEAFFLSRKARLQGKTYPWHEMGLSLADMLGRKLMALLPLSLATPIFAFAWDHRINTIHI
HSVLMVLLLFIGQEFCYYWYHRASHRIRFFWATHAVHHSPNELTLGTAYRLGLTGRLTGTAMFFAPLVWLGVRPEAVLAA
LSLNLLYQFWLHTTWIPKLGWFEYVFNTPSAHRVHHASNVDYLDANYGGVLILFDRLFGTYVEEREDEPCRFGLVHPTTT
HNPIVNQFEHWVSLGKDMMKSGSVLNAVGYLVMPPGWSHDGNGETTETLRRQAAVGV

Sequences:

>Translated_297_residues
MHNLHKITLFATVFVVAASMVEAFFLSRKARLQGKTYPWHEMGLSLADMLGRKLMALLPLSLATPIFAFAWDHRINTIHI
HSVLMVLLLFIGQEFCYYWYHRASHRIRFFWATHAVHHSPNELTLGTAYRLGLTGRLTGTAMFFAPLVWLGVRPEAVLAA
LSLNLLYQFWLHTTWIPKLGWFEYVFNTPSAHRVHHASNVDYLDANYGGVLILFDRLFGTYVEEREDEPCRFGLVHPTTT
HNPIVNQFEHWVSLGKDMMKSGSVLNAVGYLVMPPGWSHDGNGETTETLRRQAAVGV
>Mature_297_residues
MHNLHKITLFATVFVVAASMVEAFFLSRKARLQGKTYPWHEMGLSLADMLGRKLMALLPLSLATPIFAFAWDHRINTIHI
HSVLMVLLLFIGQEFCYYWYHRASHRIRFFWATHAVHHSPNELTLGTAYRLGLTGRLTGTAMFFAPLVWLGVRPEAVLAA
LSLNLLYQFWLHTTWIPKLGWFEYVFNTPSAHRVHHASNVDYLDANYGGVLILFDRLFGTYVEEREDEPCRFGLVHPTTT
HNPIVNQFEHWVSLGKDMMKSGSVLNAVGYLVMPPGWSHDGNGETTETLRRQAAVGV

Specific function: Unknown

COG id: COG3000

COG function: function code I; Sterol desaturase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sterol desaturase family [H]

Homologues:

Organism=Homo sapiens, GI51972212, Length=188, Percent_Identity=40.9574468085106, Blast_Score=148, Evalue=5e-36,
Organism=Caenorhabditis elegans, GI25144659, Length=227, Percent_Identity=33.4801762114537, Blast_Score=116, Evalue=1e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006694 [H]

Pfam domain/function: PF04116 FA_hydroxylase [H]

EC number: NA

Molecular weight: Translated: 33892; Mature: 33892

Theoretical pI: Translated: 8.65; Mature: 8.65

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHNLHKITLFATVFVVAASMVEAFFLSRKARLQGKTYPWHEMGLSLADMLGRKLMALLPL
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHH
SLATPIFAFAWDHRINTIHIHSVLMVLLLFIGQEFCYYWYHRASHRIRFFWATHAVHHSP
HHHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEEHHHCCCC
NELTLGTAYRLGLTGRLTGTAMFFAPLVWLGVRPEAVLAALSLNLLYQFWLHTTWIPKLG
CCEEECCEEEECCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCC
WFEYVFNTPSAHRVHHASNVDYLDANYGGVLILFDRLFGTYVEEREDEPCRFGLVHPTTT
HHHHHHCCCCCHHEECCCCCCEEECCCCCEEEEHHHHHHHHHHHCCCCCCEEEEECCCCC
HNPIVNQFEHWVSLGKDMMKSGSVLNAVGYLVMPPGWSHDGNGETTETLRRQAAVGV
CCHHHHHHHHHHHHHHHHHHCCCHHHHCCEEEECCCCCCCCCCCHHHHHHHHHHCCC
>Mature Secondary Structure
MHNLHKITLFATVFVVAASMVEAFFLSRKARLQGKTYPWHEMGLSLADMLGRKLMALLPL
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHH
SLATPIFAFAWDHRINTIHIHSVLMVLLLFIGQEFCYYWYHRASHRIRFFWATHAVHHSP
HHHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEEHHHCCCC
NELTLGTAYRLGLTGRLTGTAMFFAPLVWLGVRPEAVLAALSLNLLYQFWLHTTWIPKLG
CCEEECCEEEECCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCC
WFEYVFNTPSAHRVHHASNVDYLDANYGGVLILFDRLFGTYVEEREDEPCRFGLVHPTTT
HHHHHHCCCCCHHEECCCCCCEEECCCCCEEEEHHHHHHHHHHHCCCCCCEEEEECCCCC
HNPIVNQFEHWVSLGKDMMKSGSVLNAVGYLVMPPGWSHDGNGETTETLRRQAAVGV
CCHHHHHHHHHHHHHHHHHHCCCHHHHCCEEEECCCCCCCCCCCHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]