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The map label for this gene is yadA [H]

Identifier: 73540083

GI number: 73540083

Start: 412399

End: 413670

Strand: Direct

Name: yadA [H]

Synonym: Reut_A0377

Alternate gene names: 73540083

Gene position: 412399-413670 (Clockwise)

Preceding gene: 73540081

Following gene: 73540084

Centisome position: 10.83

GC content: 64.86

Gene sequence:

>1272_bases
ATGAGAAGTCATAAGAACGGGAGCTGCGGTTCCGGGCACATTTTGATCAGCGGCTTATCCCGGGTTTCGAAAGGACTGGT
TGCCGTATCGACGCTGGCGTTTGGCATGGCGGAGTCGAATGCCAGCGTGGTCATCGACAATTATCAGTTTTCGGGTGGGG
GCACGATCTGTTCAAAAATTGAACCGGGTCAGGTGGCGATGGGTGCCGACGGCGGCAGCGGTTGCGTGGCTCCTGAGTGG
GGGCCGGGGCCGTCCAGCGCTGGAAATCCGGGGCAAAACATCGTTATGTACCCGAACATAAACATTAACGGTGAGGTGGA
TTCCCTATCGATTGGTGGCTACCTCGATGTCTGGAAGGCTGCAACCTTCTTTGACGGCGTGAACATGCAAGGCACGAGAA
TCAGCATGCTTGGCGCGGGCACCGGCGACCAGGACGCCGTCAACGTGAGCCAGCTCAAGGGCGGACTCGCGGCGCTCGGC
GGCGGAGCGGGTGTTGCCGCCGATGGCTCGGTCATCGCGCCGAGCTACACGCTCGGCGGCGGCACGTTCAATGACGTCGG
TTCTGCACTGAGCAATCTTGACGGACGCATCACCAGCATGGGGCAACAGGGTGGTGGTGGCGCTTCGGAAAATGCCTATT
TCCACGCGGACGGCAAGCTCGATGGCAGCGATGCCGCGGTCGTCGCCGCCGGCACACTGGGCGTAGCGGCCGGTGCTAAC
GCGCAGGCACAGGCCACCAACAGCGTCGCGATCGGTGCGAACGCGCAGGCGATGGCCAGTGACTCCGCGGCACTCGGCGC
AAATGCGCAGGCAACGGCCCAGGGCAGCGTGGCGATCGGCACCAATTCGGTAGCGGACCGCGCCAATACGGTGTCGGTGG
GCGCGGCCGGCGCCGAGCGCCAGATCACGAACGTGGCGGCCGCGACGCAAGACACCGATGCGGTCAACCTTGGGCAACTG
CGCGATTACGCCAACGAGGCCGGCCGGCAGGCCGTCAGCCAGGCCAACAGCTACACCGACCAACGCGTCGACGCCCTGAG
CCGCGAAGCTCACGCGGGCACGGCGGCCGCCATGGCCATGGCCGGACTGCCGCAGGCGACCATTCCGGGCAAGAGCATGA
TTGCCCTTGGCGGTGCGACTTACCGTGGCCAGAGCGGTCTGGCGATCGGTGCCTCGGTGATGTCGCCGGGCGGTCGCTGG
GTGTACAAGCTGACCGGCAGCACCGCGCGCAATACGTATGGCGCGAGCCTTGCCGCCGGATTCCACTGGTAA

Upstream 100 bases:

>100_bases
TTCTTGGATCGAAACGAATAATTCCCATTGCTCTGCAAGGTGCGGAGCAAAAAGAAATGAAACAACGGATTAATGGGAAT
TTTTTCAGGGAGATATCTTT

Downstream 100 bases:

>100_bases
GCCATCGGCGCTCCGCGCAACGTGCGGGGGCGTCTGCTATCTTGGATCGAGGATCAGCAACGTCCCGCCGTCGGCATGCA
ACGCGGGTGCTGGCACCGGG

Product: YadA-like protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 423; Mature: 423

Protein sequence:

>423_residues
MRSHKNGSCGSGHILISGLSRVSKGLVAVSTLAFGMAESNASVVIDNYQFSGGGTICSKIEPGQVAMGADGGSGCVAPEW
GPGPSSAGNPGQNIVMYPNININGEVDSLSIGGYLDVWKAATFFDGVNMQGTRISMLGAGTGDQDAVNVSQLKGGLAALG
GGAGVAADGSVIAPSYTLGGGTFNDVGSALSNLDGRITSMGQQGGGGASENAYFHADGKLDGSDAAVVAAGTLGVAAGAN
AQAQATNSVAIGANAQAMASDSAALGANAQATAQGSVAIGTNSVADRANTVSVGAAGAERQITNVAAATQDTDAVNLGQL
RDYANEAGRQAVSQANSYTDQRVDALSREAHAGTAAAMAMAGLPQATIPGKSMIALGGATYRGQSGLAIGASVMSPGGRW
VYKLTGSTARNTYGASLAAGFHW

Sequences:

>Translated_423_residues
MRSHKNGSCGSGHILISGLSRVSKGLVAVSTLAFGMAESNASVVIDNYQFSGGGTICSKIEPGQVAMGADGGSGCVAPEW
GPGPSSAGNPGQNIVMYPNININGEVDSLSIGGYLDVWKAATFFDGVNMQGTRISMLGAGTGDQDAVNVSQLKGGLAALG
GGAGVAADGSVIAPSYTLGGGTFNDVGSALSNLDGRITSMGQQGGGGASENAYFHADGKLDGSDAAVVAAGTLGVAAGAN
AQAQATNSVAIGANAQAMASDSAALGANAQATAQGSVAIGTNSVADRANTVSVGAAGAERQITNVAAATQDTDAVNLGQL
RDYANEAGRQAVSQANSYTDQRVDALSREAHAGTAAAMAMAGLPQATIPGKSMIALGGATYRGQSGLAIGASVMSPGGRW
VYKLTGSTARNTYGASLAAGFHW
>Mature_423_residues
MRSHKNGSCGSGHILISGLSRVSKGLVAVSTLAFGMAESNASVVIDNYQFSGGGTICSKIEPGQVAMGADGGSGCVAPEW
GPGPSSAGNPGQNIVMYPNININGEVDSLSIGGYLDVWKAATFFDGVNMQGTRISMLGAGTGDQDAVNVSQLKGGLAALG
GGAGVAADGSVIAPSYTLGGGTFNDVGSALSNLDGRITSMGQQGGGGASENAYFHADGKLDGSDAAVVAAGTLGVAAGAN
AQAQATNSVAIGANAQAMASDSAALGANAQATAQGSVAIGTNSVADRANTVSVGAAGAERQITNVAAATQDTDAVNLGQL
RDYANEAGRQAVSQANSYTDQRVDALSREAHAGTAAAMAMAGLPQATIPGKSMIALGGATYRGQSGLAIGASVMSPGGRW
VYKLTGSTARNTYGASLAAGFHW

Specific function: Collagen-binding outer membrane protein forming a fibrillar matrix on the bacterial cell surface. Promotes initial attachment and invasion of eukaryotic cells. Also protects the bacteria by being responsible for agglutination, serum resistance, complement

COG id: COG5295

COG function: function code UW; Autotransporter adhesin

Gene ontology:

Cell location: Cell outer membrane [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the autotransporter-2 (TC 1.B.40) / oligomeric coiled-coil adhesin (Oca) family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008640
- InterPro:   IPR008635
- InterPro:   IPR008126
- InterPro:   IPR005594 [H]

Pfam domain/function: PF05658 Hep_Hag; PF05662 HIM; PF03895 YadA [H]

EC number: NA

Molecular weight: Translated: 41517; Mature: 41517

Theoretical pI: Translated: 5.05; Mature: 5.05

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRSHKNGSCGSGHILISGLSRVSKGLVAVSTLAFGMAESNASVVIDNYQFSGGGTICSKI
CCCCCCCCCCCCEEEEEEHHHHHHHHHHHHHHHHHHCCCCCEEEEECEEECCCCEEEECC
EPGQVAMGADGGSGCVAPEWGPGPSSAGNPGQNIVMYPNININGEVDSLSIGGYLDVWKA
CCCCEEEECCCCCCCCCCCCCCCCCCCCCCCCEEEEECCCCCCCCCCEEEECCHHHHHHH
ATFFDGVNMQGTRISMLGAGTGDQDAVNVSQLKGGLAALGGGAGVAADGSVIAPSYTLGG
HHHHCCCCCCCCEEEEEECCCCCCCCEEHHHHCCCCEEECCCCCCCCCCCEECCEEEECC
GTFNDVGSALSNLDGRITSMGQQGGGGASENAYFHADGKLDGSDAAVVAAGTLGVAAGAN
CCHHHHHHHHHHCCCCEEECCCCCCCCCCCCCEEEECCCCCCCCCEEEEECCEEEECCCC
AQAQATNSVAIGANAQAMASDSAALGANAQATAQGSVAIGTNSVADRANTVSVGAAGAER
CCCCCCCCEEECCCCHHHCCCCHHCCCCCCCCCCCCEEECCCCHHCCCCEEEECCCCCCH
QITNVAAATQDTDAVNLGQLRDYANEAGRQAVSQANSYTDQRVDALSREAHAGTAAAMAM
HHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHH
AGLPQATIPGKSMIALGGATYRGQSGLAIGASVMSPGGRWVYKLTGSTARNTYGASLAAG
HCCCCCCCCCCCEEEECCCEECCCCCCEEEHHHCCCCCCEEEEEECCCCCCCCCCCEECC
FHW
CCC
>Mature Secondary Structure
MRSHKNGSCGSGHILISGLSRVSKGLVAVSTLAFGMAESNASVVIDNYQFSGGGTICSKI
CCCCCCCCCCCCEEEEEEHHHHHHHHHHHHHHHHHHCCCCCEEEEECEEECCCCEEEECC
EPGQVAMGADGGSGCVAPEWGPGPSSAGNPGQNIVMYPNININGEVDSLSIGGYLDVWKA
CCCCEEEECCCCCCCCCCCCCCCCCCCCCCCCEEEEECCCCCCCCCCEEEECCHHHHHHH
ATFFDGVNMQGTRISMLGAGTGDQDAVNVSQLKGGLAALGGGAGVAADGSVIAPSYTLGG
HHHHCCCCCCCCEEEEEECCCCCCCCEEHHHHCCCCEEECCCCCCCCCCCEECCEEEECC
GTFNDVGSALSNLDGRITSMGQQGGGGASENAYFHADGKLDGSDAAVVAAGTLGVAAGAN
CCHHHHHHHHHHCCCCEEECCCCCCCCCCCCCEEEECCCCCCCCCEEEEECCEEEECCCC
AQAQATNSVAIGANAQAMASDSAALGANAQATAQGSVAIGTNSVADRANTVSVGAAGAER
CCCCCCCCEEECCCCHHHCCCCHHCCCCCCCCCCCCEEECCCCHHCCCCEEEECCCCCCH
QITNVAAATQDTDAVNLGQLRDYANEAGRQAVSQANSYTDQRVDALSREAHAGTAAAMAM
HHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHH
AGLPQATIPGKSMIALGGATYRGQSGLAIGASVMSPGGRWVYKLTGSTARNTYGASLAAG
HCCCCCCCCCCCEEEECCCEECCCCCCEEEHHHCCCCCCEEEEEECCCCCCCCCCCEECC
FHW
CCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2761389; 7934875; 2592347; 1548243 [H]