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The map label for this gene is actP [H]

Identifier: 73540081

GI number: 73540081

Start: 408716

End: 410377

Strand: Direct

Name: actP [H]

Synonym: Reut_A0375

Alternate gene names: 73540081

Gene position: 408716-410377 (Clockwise)

Preceding gene: 73540080

Following gene: 73540083

Centisome position: 10.74

GC content: 63.66

Gene sequence:

>1662_bases
ATGAAAGCGAACCAAGCCTTCATTGCCGGCAGCGCGCTGCTGCTTTCCACCGCCGCGCTGGCCGCGGGCGGAGACCTCGG
GCAGGCCGTCCGGCAGCCGACCAACTGGACTGCCATCGGCATGTTCGTGGTATTCGTGATCGGCACGCTGTTCATTACCA
AGTGGGCCGCAAAGCGAACCACCTCCGCAGCGACCTTCTATACAGGCGGTGGCGGCATCACGGGCTTCCAGAACGGCCTG
GCCATCGCAGGCGATTTCATGTCCGCGGCCTCGTTCCTCGGCATCTCCGCGGCGGTCTATGCCAATGGCTATGACGGGCT
GATCTATTCAATCGGCTTCCTGGTCGGCTGGCCCGTCATCACGTTCCTGATGGCCGAACGCCTGCGCAATCTGGGCCGCT
TCACGTTTGCCGACGTCGCGGCGTACCGATTCAAGCAGGGACCGATCCGCGCATTCGCCGCATCGGGCACGCTTGTCGTG
GTGGCGTTCTACCTGATCGCACAGATGGTCGGTGCGGGCCAGCTCATCAAGCTGCTGTTCGGCCTGGAATACTGGATCGC
GGTGGTGATCGTCGGCGCGCTGATGATGGTGTACGTGCTGTTCGGCGGCATGACGGCCACGACGTGGGTGCAGATCATCA
AGGCGTGCCTGCTGCTCGGCGGCGCGACGTTCATGGCGTTCATGGTGCTGGCGCAGTACCACTTCAGCCCCGAGGCGCTG
TTCGCGAAGGCGGTCGAGGTCCACGCCAAGAAGGAATCGATCATGAGTCCGGGCAACTTCATCAAGGACCCGATCTCGGC
AATCTCGTTCGGCATCGCGCTGATGTTCGGCACGGCGGGCCTGCCGCACATCCTGATGCGCTTCTTCACCGTGCCCAACG
CCAAGGAAGCGCGCAAGTCGGTGTTCTGGGCAACCACATGGATCGGCTACTTCTACATCCTGACCTTCATCATCGGCTTC
GGCGCGATCGTGCTGGTCAGCACCAACCCGAGCTTCCAGGACGGCAGCGGCAAGCTGCTCGGCGGCGTCAACATGGCGGC
GGTGCACCTGGCCAGCGCGGTCGGCGGCAATGTGTTCCTTGGCTTTATCTCGGCCGTGGCGTTCGCGACGATCCTTGCTG
TGGTAGCGGGCCTGACGCTCGCCGGCGCATCGGCGGTCTCGCATGACCTCTATGCCACGGTGTTCAAGCACGGTAAGGCG
ACCAGCTCGATGGAGCTGCGCGTATCGCGCATCACGACCATCATCCTCGGCATGGTTGCGGTGGTGCTCGGCATCGTGTT
TGAAAAGCAGAACATCGCGTTCATGGTGTCGCTCGCGTTCGCTGTGGCAGCGTCGGCCAACTTCCCGGTGCTGTTCATGT
CGGTGCTGTGGAAGGGCTGCACCACGCGCGGCGCGACCATCGGCGGCTTCCTTGGCCTGCTGTCGGCGGTGGTGCTCACC
GTGCTGTCGCAAGCCGTGTGGGTCGACGTGTTCCACTTCAAGGACGCGCCGTTCCCGTACACCTCTCCGGCGCTGTTCTC
GATGACGATCGGCTTTGTCGGCATCTGGATCTTCTCGCTGACCGACAAGTCCGCACGCGCACGCCTCGACATGGCAGGTT
TCGAGGCGCAGGAGCTGCGTTCGGAGACCGGCATTGGCGCCGTGCAGGGGGCAAGCCACTGA

Upstream 100 bases:

>100_bases
TGTTCGTGATTCTCTTCACCGTGGCCATCACCGGCCTCTATGTGCGTCACGCCAATCGCGCGTATGACGAGTTGACCGAA
CAGATCAAGCGGGAGGTCGC

Downstream 100 bases:

>100_bases
CAGCGGAATCATGACGCTATCAGACACGCCCGGCTTGCGAGCCGGGCGTTTTTGTTCGAGCGGTTGCTGGTACGTCGACG
TTCTTGTTATTGGGCTGGTC

Product: acetate permease

Products: NA

Alternate protein names: Acetate permease; Acetate transporter ActP [H]

Number of amino acids: Translated: 553; Mature: 553

Protein sequence:

>553_residues
MKANQAFIAGSALLLSTAALAAGGDLGQAVRQPTNWTAIGMFVVFVIGTLFITKWAAKRTTSAATFYTGGGGITGFQNGL
AIAGDFMSAASFLGISAAVYANGYDGLIYSIGFLVGWPVITFLMAERLRNLGRFTFADVAAYRFKQGPIRAFAASGTLVV
VAFYLIAQMVGAGQLIKLLFGLEYWIAVVIVGALMMVYVLFGGMTATTWVQIIKACLLLGGATFMAFMVLAQYHFSPEAL
FAKAVEVHAKKESIMSPGNFIKDPISAISFGIALMFGTAGLPHILMRFFTVPNAKEARKSVFWATTWIGYFYILTFIIGF
GAIVLVSTNPSFQDGSGKLLGGVNMAAVHLASAVGGNVFLGFISAVAFATILAVVAGLTLAGASAVSHDLYATVFKHGKA
TSSMELRVSRITTIILGMVAVVLGIVFEKQNIAFMVSLAFAVAASANFPVLFMSVLWKGCTTRGATIGGFLGLLSAVVLT
VLSQAVWVDVFHFKDAPFPYTSPALFSMTIGFVGIWIFSLTDKSARARLDMAGFEAQELRSETGIGAVQGASH

Sequences:

>Translated_553_residues
MKANQAFIAGSALLLSTAALAAGGDLGQAVRQPTNWTAIGMFVVFVIGTLFITKWAAKRTTSAATFYTGGGGITGFQNGL
AIAGDFMSAASFLGISAAVYANGYDGLIYSIGFLVGWPVITFLMAERLRNLGRFTFADVAAYRFKQGPIRAFAASGTLVV
VAFYLIAQMVGAGQLIKLLFGLEYWIAVVIVGALMMVYVLFGGMTATTWVQIIKACLLLGGATFMAFMVLAQYHFSPEAL
FAKAVEVHAKKESIMSPGNFIKDPISAISFGIALMFGTAGLPHILMRFFTVPNAKEARKSVFWATTWIGYFYILTFIIGF
GAIVLVSTNPSFQDGSGKLLGGVNMAAVHLASAVGGNVFLGFISAVAFATILAVVAGLTLAGASAVSHDLYATVFKHGKA
TSSMELRVSRITTIILGMVAVVLGIVFEKQNIAFMVSLAFAVAASANFPVLFMSVLWKGCTTRGATIGGFLGLLSAVVLT
VLSQAVWVDVFHFKDAPFPYTSPALFSMTIGFVGIWIFSLTDKSARARLDMAGFEAQELRSETGIGAVQGASH
>Mature_553_residues
MKANQAFIAGSALLLSTAALAAGGDLGQAVRQPTNWTAIGMFVVFVIGTLFITKWAAKRTTSAATFYTGGGGITGFQNGL
AIAGDFMSAASFLGISAAVYANGYDGLIYSIGFLVGWPVITFLMAERLRNLGRFTFADVAAYRFKQGPIRAFAASGTLVV
VAFYLIAQMVGAGQLIKLLFGLEYWIAVVIVGALMMVYVLFGGMTATTWVQIIKACLLLGGATFMAFMVLAQYHFSPEAL
FAKAVEVHAKKESIMSPGNFIKDPISAISFGIALMFGTAGLPHILMRFFTVPNAKEARKSVFWATTWIGYFYILTFIIGF
GAIVLVSTNPSFQDGSGKLLGGVNMAAVHLASAVGGNVFLGFISAVAFATILAVVAGLTLAGASAVSHDLYATVFKHGKA
TSSMELRVSRITTIILGMVAVVLGIVFEKQNIAFMVSLAFAVAASANFPVLFMSVLWKGCTTRGATIGGFLGLLSAVVLT
VLSQAVWVDVFHFKDAPFPYTSPALFSMTIGFVGIWIFSLTDKSARARLDMAGFEAQELRSETGIGAVQGASH

Specific function: Transports acetate [H]

COG id: COG4147

COG function: function code R; Predicted symporter

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family [H]

Homologues:

Organism=Homo sapiens, GI310128183, Length=458, Percent_Identity=21.8340611353712, Blast_Score=78, Evalue=2e-14,
Organism=Escherichia coli, GI1790503, Length=539, Percent_Identity=67.9035250463822, Blast_Score=723, Evalue=0.0,
Organism=Escherichia coli, GI1787251, Length=511, Percent_Identity=25.0489236790607, Blast_Score=82, Evalue=8e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014083
- InterPro:   IPR001734
- InterPro:   IPR018212
- InterPro:   IPR019900 [H]

Pfam domain/function: PF00474 SSF [H]

EC number: NA

Molecular weight: Translated: 58489; Mature: 58489

Theoretical pI: Translated: 10.05; Mature: 10.05

Prosite motif: PS00456 NA_SOLUT_SYMP_1 ; PS50283 NA_SOLUT_SYMP_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHCCCCCCCCCCC
>Mature Secondary Structure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HHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA