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The map label for this gene is coaD [H]

Identifier: 73540044

GI number: 73540044

Start: 368511

End: 368996

Strand: Direct

Name: coaD [H]

Synonym: Reut_A0338

Alternate gene names: 73540044

Gene position: 368511-368996 (Clockwise)

Preceding gene: 73540043

Following gene: 73540045

Centisome position: 9.68

GC content: 60.91

Gene sequence:

>486_bases
ATGGCCATCGCGGTCTACCCCGGTACGTTTGATCCCATGACCCGGGGGCACGAGGATCTGGTCCGCCGTGCGTCGAACAT
TTTCGACGAACTGGTGGTTGGCGTGGCGCACAGCCCCAACAAGCGCCCGTTTTTCTCGCTCGAAGAGCGCATCAGCATCG
CCCGTGAAGTGCTGGGCCACTACCCCAACGTGCGCGTAGAGGGCTTTGCCGGGCTGCTCAAGGATTTCGTCCGCAAGAAC
AATGCGCGCGTGATCGTCCGTGGCCTGCGCGCCGTGTCGGATTTCGAGTACGAGTTCCAGATGGCGGGCATGAACCGCTA
CCTGCTGCCGGACGTGGAAACCATGTTCCTGACGCCGTCCGATCAGTACCAGTTCATCTCCGGGACCTTCGTGCGCGAGA
TTGCGGTGCTTGGCGGCGATGTCAGCAAATTCGTGTTCCCGTCGGTGGAGCGGTGGCTCGCTGAGAAAATCAGCAAACCG
GAATAA

Upstream 100 bases:

>100_bases
GCCGCTGTTACAACGCTCGCGACGCATCAACCACCCGTCGGCAGCCGGCAGGCAAGGCGGTCCGGAAAAGGACCGGCAGC
GGGCAGATCAAGGAGGAAGT

Downstream 100 bases:

>100_bases
AATGACGGTTTCAGACGCGTCGATCCGCGGCCAGTTCGGGCGCGGGCGCGTCCGCAGGAAGGAAACACCATGGCGCTACT
GATCACCGACGACTGCATCA

Product: phosphopantetheine adenylyltransferase

Products: NA

Alternate protein names: Dephospho-CoA pyrophosphorylase; Pantetheine-phosphate adenylyltransferase; PPAT [H]

Number of amino acids: Translated: 161; Mature: 160

Protein sequence:

>161_residues
MAIAVYPGTFDPMTRGHEDLVRRASNIFDELVVGVAHSPNKRPFFSLEERISIAREVLGHYPNVRVEGFAGLLKDFVRKN
NARVIVRGLRAVSDFEYEFQMAGMNRYLLPDVETMFLTPSDQYQFISGTFVREIAVLGGDVSKFVFPSVERWLAEKISKP
E

Sequences:

>Translated_161_residues
MAIAVYPGTFDPMTRGHEDLVRRASNIFDELVVGVAHSPNKRPFFSLEERISIAREVLGHYPNVRVEGFAGLLKDFVRKN
NARVIVRGLRAVSDFEYEFQMAGMNRYLLPDVETMFLTPSDQYQFISGTFVREIAVLGGDVSKFVFPSVERWLAEKISKP
E
>Mature_160_residues
AIAVYPGTFDPMTRGHEDLVRRASNIFDELVVGVAHSPNKRPFFSLEERISIAREVLGHYPNVRVEGFAGLLKDFVRKNN
ARVIVRGLRAVSDFEYEFQMAGMNRYLLPDVETMFLTPSDQYQFISGTFVREIAVLGGDVSKFVFPSVERWLAEKISKPE

Specific function: Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate [H]

COG id: COG0669

COG function: function code H; Phosphopantetheine adenylyltransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial CoaD family [H]

Homologues:

Organism=Escherichia coli, GI1790065, Length=155, Percent_Identity=48.3870967741936, Blast_Score=177, Evalue=3e-46,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004821
- InterPro:   IPR004820
- InterPro:   IPR001980
- InterPro:   IPR014729 [H]

Pfam domain/function: PF01467 CTP_transf_2 [H]

EC number: =2.7.7.3 [H]

Molecular weight: Translated: 18332; Mature: 18201

Theoretical pI: Translated: 6.81; Mature: 6.81

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAIAVYPGTFDPMTRGHEDLVRRASNIFDELVVGVAHSPNKRPFFSLEERISIAREVLGH
CEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHC
YPNVRVEGFAGLLKDFVRKNNARVIVRGLRAVSDFEYEFQMAGMNRYLLPDVETMFLTPS
CCCCEEHHHHHHHHHHHHCCCCEEHHHHHHHHHCCCCEEEECCCCCCCCCCCEEEEECCC
DQYQFISGTFVREIAVLGGDVSKFVFPSVERWLAEKISKPE
CCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
AIAVYPGTFDPMTRGHEDLVRRASNIFDELVVGVAHSPNKRPFFSLEERISIAREVLGH
EEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHC
YPNVRVEGFAGLLKDFVRKNNARVIVRGLRAVSDFEYEFQMAGMNRYLLPDVETMFLTPS
CCCCEEHHHHHHHHHHHHCCCCEEHHHHHHHHHCCCCEEEECCCCCCCCCCCEEEEECCC
DQYQFISGTFVREIAVLGGDVSKFVFPSVERWLAEKISKPE
CCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11823852 [H]