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The map label for this gene is gpmA [H]

Identifier: 73540010

GI number: 73540010

Start: 336930

End: 337676

Strand: Reverse

Name: gpmA [H]

Synonym: Reut_A0304

Alternate gene names: 73540010

Gene position: 337676-336930 (Counterclockwise)

Preceding gene: 73540016

Following gene: 73540009

Centisome position: 8.87

GC content: 65.73

Gene sequence:

>747_bases
ATGTACAAGCTAGTCCTCATCCGCCACGGCGAATCGACGTGGAACCTCGAAAACCGCTTCACCGGCTGGGTCGACGTCGA
CCTGACTGACACCGGCGCCGCGCAAGCCCGCCTGGCCGGCAAGCTGCTCAAGGAAGCCGGCTTCGCCTTCGACGTGGCCT
ACACGTCCGTGCTCAAGCGCGCGATCCGTACGCTGTGGCACGTGCAGGACGAAATGGACGAGATGTGGATCCCGGTACGC
AACGAATGGCGCCTGAACGAGCGCCACTACGGTGCGCTGGCCGGCCTGAACAAGGCAGAAACCGCCGCCAAGTTCGGCGA
CGAGCAGGTGCTCGTGTGGCGCCGCAGCTACGACACGCCGCCGCCCGCGCTGGAGCCGACCGATCCGCGTGCCTCTTACG
ACGATCCGCGCTACGCCAATGTGCCGCGCGAGCAGATTCCGCTGACCGAATGCCTGAAGGACACCGTGGCCCGCGTGCTG
CCGCTGTGGAACGAATCCATCGCTCCGGACATCCAATCGGGCAAGCGCGTGGTCATTGCCGCTCACGGCAACAGCATCCG
CGCCCTGGTTAAGTACCTGGATCAGATTTCGGATGACGATATCGTCGGCCTCAACATCCCCAATGGCACCCCGCTCGTCT
ACGAGCTGGACGCCAGCCTGCGCCCGCTGCGCCACTATTACCTGGGCGACCAGGAAGCCATCGCCGCCTCGCTGGCGGCC
GTGGCCAGCCAGGGCAAGGCCCGCTGA

Upstream 100 bases:

>100_bases
CGCCTCTTTGTCGCTTCCCGGGCACACAGGAACACCGGCAGGCGGCACCGATGCGGCGGCCCCGGCGCACGCAGGTTATT
TACTCTCTGGAAGCAGCAGC

Downstream 100 bases:

>100_bases
AGGCCCGCCGGGCGGCATGCACCACCCAAAGTGCGGCCGCCCACCGACAGCCGGTACGTGACAGGCCTATTTCTCCACAC
CGTTTTATACTGTCGGACAA

Product: phosphoglyceromutase

Products: NA

Alternate protein names: BPG-dependent PGAM; PGAM; Phosphoglyceromutase; dPGM [H]

Number of amino acids: Translated: 248; Mature: 248

Protein sequence:

>248_residues
MYKLVLIRHGESTWNLENRFTGWVDVDLTDTGAAQARLAGKLLKEAGFAFDVAYTSVLKRAIRTLWHVQDEMDEMWIPVR
NEWRLNERHYGALAGLNKAETAAKFGDEQVLVWRRSYDTPPPALEPTDPRASYDDPRYANVPREQIPLTECLKDTVARVL
PLWNESIAPDIQSGKRVVIAAHGNSIRALVKYLDQISDDDIVGLNIPNGTPLVYELDASLRPLRHYYLGDQEAIAASLAA
VASQGKAR

Sequences:

>Translated_248_residues
MYKLVLIRHGESTWNLENRFTGWVDVDLTDTGAAQARLAGKLLKEAGFAFDVAYTSVLKRAIRTLWHVQDEMDEMWIPVR
NEWRLNERHYGALAGLNKAETAAKFGDEQVLVWRRSYDTPPPALEPTDPRASYDDPRYANVPREQIPLTECLKDTVARVL
PLWNESIAPDIQSGKRVVIAAHGNSIRALVKYLDQISDDDIVGLNIPNGTPLVYELDASLRPLRHYYLGDQEAIAASLAA
VASQGKAR
>Mature_248_residues
MYKLVLIRHGESTWNLENRFTGWVDVDLTDTGAAQARLAGKLLKEAGFAFDVAYTSVLKRAIRTLWHVQDEMDEMWIPVR
NEWRLNERHYGALAGLNKAETAAKFGDEQVLVWRRSYDTPPPALEPTDPRASYDDPRYANVPREQIPLTECLKDTVARVL
PLWNESIAPDIQSGKRVVIAAHGNSIRALVKYLDQISDDDIVGLNIPNGTPLVYELDASLRPLRHYYLGDQEAIAASLAA
VASQGKAR

Specific function: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate [H]

COG id: COG0588

COG function: function code G; Phosphoglycerate mutase 1

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily [H]

Homologues:

Organism=Homo sapiens, GI50593010, Length=250, Percent_Identity=54.4, Blast_Score=298, Evalue=3e-81,
Organism=Homo sapiens, GI4505753, Length=250, Percent_Identity=58.4, Blast_Score=296, Evalue=2e-80,
Organism=Homo sapiens, GI71274132, Length=250, Percent_Identity=56.4, Blast_Score=284, Evalue=7e-77,
Organism=Homo sapiens, GI4502445, Length=252, Percent_Identity=50.3968253968254, Blast_Score=272, Evalue=2e-73,
Organism=Homo sapiens, GI40353764, Length=252, Percent_Identity=50.3968253968254, Blast_Score=272, Evalue=2e-73,
Organism=Homo sapiens, GI310129614, Length=162, Percent_Identity=61.7283950617284, Blast_Score=196, Evalue=2e-50,
Organism=Escherichia coli, GI1786970, Length=246, Percent_Identity=62.6016260162602, Blast_Score=323, Evalue=9e-90,
Organism=Saccharomyces cerevisiae, GI6322697, Length=246, Percent_Identity=53.6585365853659, Blast_Score=243, Evalue=2e-65,
Organism=Saccharomyces cerevisiae, GI6324516, Length=294, Percent_Identity=34.0136054421769, Blast_Score=143, Evalue=2e-35,
Organism=Saccharomyces cerevisiae, GI6320183, Length=296, Percent_Identity=30.7432432432432, Blast_Score=135, Evalue=7e-33,
Organism=Drosophila melanogaster, GI24646216, Length=251, Percent_Identity=52.9880478087649, Blast_Score=270, Evalue=5e-73,
Organism=Drosophila melanogaster, GI85725270, Length=251, Percent_Identity=52.5896414342629, Blast_Score=260, Evalue=6e-70,
Organism=Drosophila melanogaster, GI85725272, Length=251, Percent_Identity=52.5896414342629, Blast_Score=260, Evalue=6e-70,
Organism=Drosophila melanogaster, GI24650981, Length=251, Percent_Identity=52.5896414342629, Blast_Score=260, Evalue=6e-70,
Organism=Drosophila melanogaster, GI28571815, Length=251, Percent_Identity=40.2390438247012, Blast_Score=185, Evalue=3e-47,
Organism=Drosophila melanogaster, GI28571817, Length=251, Percent_Identity=40.2390438247012, Blast_Score=184, Evalue=4e-47,
Organism=Drosophila melanogaster, GI24648979, Length=251, Percent_Identity=40.2390438247012, Blast_Score=184, Evalue=5e-47,

Paralogues:

None

Copy number: 960 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 40 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013078
- InterPro:   IPR001345
- InterPro:   IPR005952 [H]

Pfam domain/function: PF00300 PGAM [H]

EC number: =5.4.2.1 [H]

Molecular weight: Translated: 27852; Mature: 27852

Theoretical pI: Translated: 5.70; Mature: 5.70

Prosite motif: PS00175 PG_MUTASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYKLVLIRHGESTWNLENRFTGWVDVDLTDTGAAQARLAGKLLKEAGFAFDVAYTSVLKR
CEEEEEEECCCCCCCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHH
AIRTLWHVQDEMDEMWIPVRNEWRLNERHYGALAGLNKAETAAKFGDEQVLVWRRSYDTP
HHHHHHHHHHHHHHEECCCCCCEECCCHHHHHHHCCCHHHHHHHCCCCEEEEEEECCCCC
PPALEPTDPRASYDDPRYANVPREQIPLTECLKDTVARVLPLWNESIAPDIQSGKRVVIA
CCCCCCCCCCCCCCCCCCCCCCHHHCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEE
AHGNSIRALVKYLDQISDDDIVGLNIPNGTPLVYELDASLRPLRHYYLGDQEAIAASLAA
ECCCHHHHHHHHHHHCCCCCEEEEECCCCCCEEEECCCCHHHHHHHHCCCHHHHHHHHHH
VASQGKAR
HHHCCCCC
>Mature Secondary Structure
MYKLVLIRHGESTWNLENRFTGWVDVDLTDTGAAQARLAGKLLKEAGFAFDVAYTSVLKR
CEEEEEEECCCCCCCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHH
AIRTLWHVQDEMDEMWIPVRNEWRLNERHYGALAGLNKAETAAKFGDEQVLVWRRSYDTP
HHHHHHHHHHHHHHEECCCCCCEECCCHHHHHHHCCCHHHHHHHCCCCEEEEEEECCCCC
PPALEPTDPRASYDDPRYANVPREQIPLTECLKDTVARVLPLWNESIAPDIQSGKRVVIA
CCCCCCCCCCCCCCCCCCCCCCHHHCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEE
AHGNSIRALVKYLDQISDDDIVGLNIPNGTPLVYELDASLRPLRHYYLGDQEAIAASLAA
ECCCHHHHHHHHHHHCCCCCEEEEECCCCCCEEEECCCCHHHHHHHHCCCHHHHHHHHHH
VASQGKAR
HHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA