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The map label for this gene is dctB [H]

Identifier: 73539982

GI number: 73539982

Start: 307486

End: 309465

Strand: Reverse

Name: dctB [H]

Synonym: Reut_A0276

Alternate gene names: 73539982

Gene position: 309465-307486 (Counterclockwise)

Preceding gene: 73539983

Following gene: 73539981

Centisome position: 8.13

GC content: 68.54

Gene sequence:

>1980_bases
ATGCCCCATTCCGACGACTTCCTCGCCGTACATGACCCCGCCGCCGCCCAGGCGGCGCACGAGCCCGGCAGCGAGAACCG
CCGCTGGTGGGGCTTTGCCGTGGCACTGGCGGCCGGCCTCGTGCTGCTATGCGCGCTGACGTGGCTGGTATCCGTGCAGC
GCGGCCTGGCAACACTGCAGGAAAGCACCGCTACACGCGCCGACCGCTACGCCGCCACGCTCGAAAGCACGCTCGACCGC
TACGAATTCCTGCCCGCGCTGGTATCGCTGCACCCGTTCGTGCGTGGCCTGCTGCAGGCGCCCGATGATCCCGCACGCGT
CGCTGCGGCCAACCATTATCTTGCTGAAGTCAACCGCCGCTCGCATGCGTCGGCCACCTACGTGATCGCCACCAACGGCA
TCGCGCTGGCCGCCAGCAACGCCGGCGAGCCCGGCAGCTTCGTCGGCACCGACTACCGCTTCCGCCCCTACTTCCAGATC
GCATCGCGCGGAGAGATGGGGCGCTTCTATGCGATCGGCATCACCAGCGACGAGCCGGGCTACTACATCGCGCAGCCCGT
GGAGTCGGGCGGCAAGGTGATCGGCGTGACGGTAGTCAAGCTCAACCTGGAGTGGTTCCAGCGTGCCGGCGGCGGCAGCG
CCGAGCCGCTGATGGTCAGCGACGACCACGGCGTGATCTTCCTGTCGTCCGTGCCTGCCTGGCAGTACCGCACGCTGGGG
CCGTTGCCGGCCGAGCTGCACGACGAGCTGGGCAAGACCCGTCAGTATCACGACCGTGATGTCACGCCGCTTCCGCTCGA
ACCGCTAACCTCGCCGGTCACCGAGTGGCTGGCCTCCAGGGCGCTCGACCCGGGCGCGCGCCTGGTGCGTGTGCGCGCCG
ACGGCCCCAACCCCGACGGCAGCGAGCGCGCGGACCGCTACCTCGAACTCGGCCGCAAGGTGGGCCCCGCGGAGTGGACC
ATGCAGGTGATGGCACCGCTCGACCCGGTGCTGGCCAATGCGCGCAATGCCACCGTGGCAGCGGCGCTGGCCTACGCGTG
CATTTGCCTGCTGCTGGTCAATTGGCGTCAGCGCCGCCAGCGCGCACGCGACATGCTGTACAGCCGCCGCCTGCTCGAAG
CCGCCTATGACGAGCTTGAGCGGCGTGTCGAAGCCCGCACGGCCGACCTGATGGCCATCAACGAAAAGCTCGAAGAAGAA
GTCGCCGAACGCACACGCGCGGAGAGCGAGTTGCGCGCGGCACAGGACGAACTCGTGCAGGCCAGCAAACTCGCTGCGCT
GGGTCAGATGGCCGCCGGCATCACGCATGAGCTGAACCAGCCGCTGGCCGCGTTGCGCACGTTCTCCGACAACACGCGCG
TGTTGCTGGAGCGTGGGCAACTCGCCGCTGCGGAAGGCAACCTGTCCGCGATTGCCGACCTCACCGAGCGCATGGGCAAG
ATCACCGGCCAGCTCAAGCTGTTTGCCGGCAAGGCGCGCCCGCCGCGCCGTTCGGTGCTGGTCAGCGCCGCGATCGAGCA
CGTGCTGGCCCTGCTGGCGCCGCGGCTGACCGGCGTGACACTGCATGTTGATGGACTCCACGCACTGCCCAACATTGCCG
TGCGCGCCGACGAACTCAAGCTTGAGCAAGTGCTGCTCAACCTGATCGGCAATGCGCTCGATGCCATCGCCAGCGCGGCG
CCTGCGCAAGGGCGCATCGACGTTTCCGTCAGCGCCGACGCAAGCGCGGTGACGATCCAGGTGCGCGACAATGGCACGGG
TATCTCGCCGGAAGACCTGCCGCGCCTGTTCGAGCCGTTCTTCACGACCAAGGAAACCGGCCAGGGGCTGGGCCTCGGCC
TGGCGATCTCCTCGTCGATCGTGCGCGAGTTCGGCGGACAACTCAGCGCCGCCAATGCTGACGGCGGCGGCGCGGTATTC
ACCATCGTGCTGACGCGCGCACCGGTCGACGCCGGCGCAGGCGTCACCCAGACACATTGA

Upstream 100 bases:

>100_bases
GCCGGCCAGAACGTCTGACGCCTCGCAGGCAAGCGGCCGGCCCGGTGGGCCGGCCGCGCCGCAGCGAGTATCATCGGCGC
GACAGCCTTCGCGCGCGCCG

Downstream 100 bases:

>100_bases
GGCATCCCATGCAAGACGGTTTGCGCGTCCTCTTCGTCGAAGATGAACCGCTGGTGCGCCAGGCCACCGCGCAAAGCCTG
GAGCTGGCCGGCTTTTCCGT

Product: sensor histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 659; Mature: 658

Protein sequence:

>659_residues
MPHSDDFLAVHDPAAAQAAHEPGSENRRWWGFAVALAAGLVLLCALTWLVSVQRGLATLQESTATRADRYAATLESTLDR
YEFLPALVSLHPFVRGLLQAPDDPARVAAANHYLAEVNRRSHASATYVIATNGIALAASNAGEPGSFVGTDYRFRPYFQI
ASRGEMGRFYAIGITSDEPGYYIAQPVESGGKVIGVTVVKLNLEWFQRAGGGSAEPLMVSDDHGVIFLSSVPAWQYRTLG
PLPAELHDELGKTRQYHDRDVTPLPLEPLTSPVTEWLASRALDPGARLVRVRADGPNPDGSERADRYLELGRKVGPAEWT
MQVMAPLDPVLANARNATVAAALAYACICLLLVNWRQRRQRARDMLYSRRLLEAAYDELERRVEARTADLMAINEKLEEE
VAERTRAESELRAAQDELVQASKLAALGQMAAGITHELNQPLAALRTFSDNTRVLLERGQLAAAEGNLSAIADLTERMGK
ITGQLKLFAGKARPPRRSVLVSAAIEHVLALLAPRLTGVTLHVDGLHALPNIAVRADELKLEQVLLNLIGNALDAIASAA
PAQGRIDVSVSADASAVTIQVRDNGTGISPEDLPRLFEPFFTTKETGQGLGLGLAISSSIVREFGGQLSAANADGGGAVF
TIVLTRAPVDAGAGVTQTH

Sequences:

>Translated_659_residues
MPHSDDFLAVHDPAAAQAAHEPGSENRRWWGFAVALAAGLVLLCALTWLVSVQRGLATLQESTATRADRYAATLESTLDR
YEFLPALVSLHPFVRGLLQAPDDPARVAAANHYLAEVNRRSHASATYVIATNGIALAASNAGEPGSFVGTDYRFRPYFQI
ASRGEMGRFYAIGITSDEPGYYIAQPVESGGKVIGVTVVKLNLEWFQRAGGGSAEPLMVSDDHGVIFLSSVPAWQYRTLG
PLPAELHDELGKTRQYHDRDVTPLPLEPLTSPVTEWLASRALDPGARLVRVRADGPNPDGSERADRYLELGRKVGPAEWT
MQVMAPLDPVLANARNATVAAALAYACICLLLVNWRQRRQRARDMLYSRRLLEAAYDELERRVEARTADLMAINEKLEEE
VAERTRAESELRAAQDELVQASKLAALGQMAAGITHELNQPLAALRTFSDNTRVLLERGQLAAAEGNLSAIADLTERMGK
ITGQLKLFAGKARPPRRSVLVSAAIEHVLALLAPRLTGVTLHVDGLHALPNIAVRADELKLEQVLLNLIGNALDAIASAA
PAQGRIDVSVSADASAVTIQVRDNGTGISPEDLPRLFEPFFTTKETGQGLGLGLAISSSIVREFGGQLSAANADGGGAVF
TIVLTRAPVDAGAGVTQTH
>Mature_658_residues
PHSDDFLAVHDPAAAQAAHEPGSENRRWWGFAVALAAGLVLLCALTWLVSVQRGLATLQESTATRADRYAATLESTLDRY
EFLPALVSLHPFVRGLLQAPDDPARVAAANHYLAEVNRRSHASATYVIATNGIALAASNAGEPGSFVGTDYRFRPYFQIA
SRGEMGRFYAIGITSDEPGYYIAQPVESGGKVIGVTVVKLNLEWFQRAGGGSAEPLMVSDDHGVIFLSSVPAWQYRTLGP
LPAELHDELGKTRQYHDRDVTPLPLEPLTSPVTEWLASRALDPGARLVRVRADGPNPDGSERADRYLELGRKVGPAEWTM
QVMAPLDPVLANARNATVAAALAYACICLLLVNWRQRRQRARDMLYSRRLLEAAYDELERRVEARTADLMAINEKLEEEV
AERTRAESELRAAQDELVQASKLAALGQMAAGITHELNQPLAALRTFSDNTRVLLERGQLAAAEGNLSAIADLTERMGKI
TGQLKLFAGKARPPRRSVLVSAAIEHVLALLAPRLTGVTLHVDGLHALPNIAVRADELKLEQVLLNLIGNALDAIASAAP
AQGRIDVSVSADASAVTIQVRDNGTGISPEDLPRLFEPFFTTKETGQGLGLGLAISSSIVREFGGQLSAANADGGGAVFT
IVLTRAPVDAGAGVTQTH

Specific function: Member of the two-component regulatory system dctB/dctD involved in the transport of C4-dicarboxylates. DctB functions as a membrane-associated protein kinase that phosphorylates dctD in response to environmental signals [H]

COG id: COG4191

COG function: function code T; Signal transduction histidine kinase regulating C4-dicarboxylate transport system

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1790436, Length=233, Percent_Identity=33.0472103004292, Blast_Score=112, Evalue=7e-26,
Organism=Escherichia coli, GI1788549, Length=240, Percent_Identity=32.9166666666667, Blast_Score=111, Evalue=1e-25,
Organism=Escherichia coli, GI145693157, Length=259, Percent_Identity=29.3436293436293, Blast_Score=82, Evalue=1e-16,
Organism=Escherichia coli, GI1789149, Length=289, Percent_Identity=27.3356401384083, Blast_Score=78, Evalue=2e-15,
Organism=Escherichia coli, GI1790861, Length=225, Percent_Identity=30.2222222222222, Blast_Score=73, Evalue=7e-14,
Organism=Escherichia coli, GI48994928, Length=255, Percent_Identity=27.0588235294118, Blast_Score=72, Evalue=8e-14,
Organism=Escherichia coli, GI87081816, Length=284, Percent_Identity=28.169014084507, Blast_Score=72, Evalue=2e-13,
Organism=Escherichia coli, GI1787894, Length=235, Percent_Identity=28.936170212766, Blast_Score=69, Evalue=1e-12,
Organism=Escherichia coli, GI1790346, Length=274, Percent_Identity=28.1021897810219, Blast_Score=67, Evalue=3e-12,
Organism=Escherichia coli, GI1789808, Length=260, Percent_Identity=25.7692307692308, Blast_Score=64, Evalue=4e-11,
Organism=Escherichia coli, GI1786600, Length=225, Percent_Identity=26.2222222222222, Blast_Score=64, Evalue=4e-11,
Organism=Escherichia coli, GI1786783, Length=232, Percent_Identity=31.4655172413793, Blast_Score=63, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR017055
- InterPro:   IPR009082 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 70853; Mature: 70722

Theoretical pI: Translated: 5.92; Mature: 5.92

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPHSDDFLAVHDPAAAQAAHEPGSENRRWWGFAVALAAGLVLLCALTWLVSVQRGLATLQ
CCCCCCEEEEECCHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ESTATRADRYAATLESTLDRYEFLPALVSLHPFVRGLLQAPDDPARVAAANHYLAEVNRR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCC
SHASATYVIATNGIALAASNAGEPGSFVGTDYRFRPYFQIASRGEMGRFYAIGITSDEPG
CCCCEEEEEEECCEEEEECCCCCCCCCCCCCCEECHHHHHHCCCCCCEEEEEEECCCCCC
YYIAQPVESGGKVIGVTVVKLNLEWFQRAGGGSAEPLMVSDDHGVIFLSSVPAWQYRTLG
EEEECCCCCCCCEEEEEEEEEEHHHHHHCCCCCCCCEEEECCCCEEEEECCCCCCCCCCC
PLPAELHDELGKTRQYHDRDVTPLPLEPLTSPVTEWLASRALDPGARLVRVRADGPNPDG
CCCHHHHHHHCCHHHCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCEEEEEECCCCCCCC
SERADRYLELGRKVGPAEWTMQVMAPLDPVLANARNATVAAALAYACICLLLVNWRQRRQ
HHHHHHHHHHHCCCCCHHHHHHHHHCCCHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHH
RARDMLYSRRLLEAAYDELERRVEARTADLMAINEKLEEEVAERTRAESELRAAQDELVQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ASKLAALGQMAAGITHELNQPLAALRTFSDNTRVLLERGQLAAAEGNLSAIADLTERMGK
HHHHHHHHHHHHHHHHHHCCHHHHHHHCCCCCEEEEECCCEEECCCCHHHHHHHHHHHHH
ITGQLKLFAGKARPPRRSVLVSAAIEHVLALLAPRLTGVTLHVDGLHALPNIAVRADELK
HHCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHCCEEEEECCHHHCCCCEEEHHHHH
LEQVLLNLIGNALDAIASAAPAQGRIDVSVSADASAVTIQVRDNGTGISPEDLPRLFEPF
HHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCEEEEEEEECCCCCCCHHHHHHHHHHH
FTTKETGQGLGLGLAISSSIVREFGGQLSAANADGGGAVFTIVLTRAPVDAGAGVTQTH
HCCCCCCCCCEEHHHHHHHHHHHHCCCEEECCCCCCCEEEEEEEEECCCCCCCCCCCCC
>Mature Secondary Structure 
PHSDDFLAVHDPAAAQAAHEPGSENRRWWGFAVALAAGLVLLCALTWLVSVQRGLATLQ
CCCCCEEEEECCHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ESTATRADRYAATLESTLDRYEFLPALVSLHPFVRGLLQAPDDPARVAAANHYLAEVNRR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCC
SHASATYVIATNGIALAASNAGEPGSFVGTDYRFRPYFQIASRGEMGRFYAIGITSDEPG
CCCCEEEEEEECCEEEEECCCCCCCCCCCCCCEECHHHHHHCCCCCCEEEEEEECCCCCC
YYIAQPVESGGKVIGVTVVKLNLEWFQRAGGGSAEPLMVSDDHGVIFLSSVPAWQYRTLG
EEEECCCCCCCCEEEEEEEEEEHHHHHHCCCCCCCCEEEECCCCEEEEECCCCCCCCCCC
PLPAELHDELGKTRQYHDRDVTPLPLEPLTSPVTEWLASRALDPGARLVRVRADGPNPDG
CCCHHHHHHHCCHHHCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCEEEEEECCCCCCCC
SERADRYLELGRKVGPAEWTMQVMAPLDPVLANARNATVAAALAYACICLLLVNWRQRRQ
HHHHHHHHHHHCCCCCHHHHHHHHHCCCHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHH
RARDMLYSRRLLEAAYDELERRVEARTADLMAINEKLEEEVAERTRAESELRAAQDELVQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ASKLAALGQMAAGITHELNQPLAALRTFSDNTRVLLERGQLAAAEGNLSAIADLTERMGK
HHHHHHHHHHHHHHHHHHCCHHHHHHHCCCCCEEEEECCCEEECCCCHHHHHHHHHHHHH
ITGQLKLFAGKARPPRRSVLVSAAIEHVLALLAPRLTGVTLHVDGLHALPNIAVRADELK
HHCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHCCEEEEECCHHHCCCCEEEHHHHH
LEQVLLNLIGNALDAIASAAPAQGRIDVSVSADASAVTIQVRDNGTGISPEDLPRLFEPF
HHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCEEEEEEEECCCCCCCHHHHHHHHHHH
FTTKETGQGLGLGLAISSSIVREFGGQLSAANADGGGAVFTIVLTRAPVDAGAGVTQTH
HCCCCCCCCCEEHHHHHHHHHHHHCCCEEECCCCCCCEEEEEEEEECCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 3671068 [H]