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The map label for this gene is mhpR [H]

Identifier: 73539975

GI number: 73539975

Start: 299000

End: 299782

Strand: Reverse

Name: mhpR [H]

Synonym: Reut_A0269

Alternate gene names: 73539975

Gene position: 299782-299000 (Counterclockwise)

Preceding gene: 73539981

Following gene: 73539974

Centisome position: 7.88

GC content: 65.52

Gene sequence:

>783_bases
ATGACCAAGTACGCCAACGTGCGGGGGTTGTCACGCGGCCTGCAGGTGCTGCGGGCGCTCAATGCCATGGAAAACGGCCG
TGCCACCAGCCAGCAGCTCAGCGAGGCCACGGGCCTGCACCGGACCACCGTGCGGCGTTTGCTGGAAACACTGGTCGAAG
AAGGCTTCGTGCGGCGCAGTACATCGGACGACAGCTTCCGCCTGACACTCGACGTGCGCGCGCTCAGCGAAGGCTTCACC
GACGACGAACGCATCGCCACCATCGCGCCGCCGATCATGGGGCGGCTGCTGCAGCGCGTAGTGTGGCCGTCCGACCTGAC
CACGCCCGACGGCGACGCCATGATCATCCGCGAAACCACGCACCGCTTCAGCCCGCTGTCGTTTCACCGCTCCATGGTCG
GCAGGCGGCTGCCGATCCTGCTGACCTCCGCGGGCCGCGTGTATTTCTCGATGTGCCCGGATGCCGAACGCGAAGACATT
CTCGAAGTGCTGCGCTCAGGCGCGGGCGGCGAACAGCAGCTCAAGCTGGCGATGGACGACGCGTATATCCGCAACCTGAT
CCGGCAGACCCGCAAGGATGGATTCGGGTCGAATCATGGTGACTGGGCGGATCAGAAGAAGATCGGGGCGGTGGCCGTAG
CGATCCAGGCGGAGGGGCGGGTGCTGGCGAGCCTGAATGTCGTTTATCTGGAGCAAGCGATCAGTCCGGCAGAGGCGACG
CGGCGGTTTGTGCCGGAGTTGCAGCAGGCGGCGAAGGAGATGGTAGCTGCGTTGAGCGCGTAG

Upstream 100 bases:

>100_bases
TTTGCGATTTTCAGAGGAGTCTAGGCATCCGCCAGCGCGCGCTCAAACATTTCTATAAAATGTGCAAGGAGTGCACATCT
TTGATTTTTAAGGATTTTCG

Downstream 100 bases:

>100_bases
TCGCGGCGTAAGCCGCCCCGCGGTTGCGCACCGCCCCGACGATTCCCCGATTTGGCGTAGATTGACGCTTCTAGCCCCTG
CAATCGGAAAATCCCTATAA

Product: DNA-binding transcriptional activator MhpR

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 260; Mature: 259

Protein sequence:

>260_residues
MTKYANVRGLSRGLQVLRALNAMENGRATSQQLSEATGLHRTTVRRLLETLVEEGFVRRSTSDDSFRLTLDVRALSEGFT
DDERIATIAPPIMGRLLQRVVWPSDLTTPDGDAMIIRETTHRFSPLSFHRSMVGRRLPILLTSAGRVYFSMCPDAEREDI
LEVLRSGAGGEQQLKLAMDDAYIRNLIRQTRKDGFGSNHGDWADQKKIGAVAVAIQAEGRVLASLNVVYLEQAISPAEAT
RRFVPELQQAAKEMVAALSA

Sequences:

>Translated_260_residues
MTKYANVRGLSRGLQVLRALNAMENGRATSQQLSEATGLHRTTVRRLLETLVEEGFVRRSTSDDSFRLTLDVRALSEGFT
DDERIATIAPPIMGRLLQRVVWPSDLTTPDGDAMIIRETTHRFSPLSFHRSMVGRRLPILLTSAGRVYFSMCPDAEREDI
LEVLRSGAGGEQQLKLAMDDAYIRNLIRQTRKDGFGSNHGDWADQKKIGAVAVAIQAEGRVLASLNVVYLEQAISPAEAT
RRFVPELQQAAKEMVAALSA
>Mature_259_residues
TKYANVRGLSRGLQVLRALNAMENGRATSQQLSEATGLHRTTVRRLLETLVEEGFVRRSTSDDSFRLTLDVRALSEGFTD
DERIATIAPPIMGRLLQRVVWPSDLTTPDGDAMIIRETTHRFSPLSFHRSMVGRRLPILLTSAGRVYFSMCPDAEREDIL
EVLRSGAGGEQQLKLAMDDAYIRNLIRQTRKDGFGSNHGDWADQKKIGAVAVAIQAEGRVLASLNVVYLEQAISPAEATR
RFVPELQQAAKEMVAALSA

Specific function: Activator of the mhpRABCDEF operon coding for components of the 3-hydroxyphenylpropionate degradation pathway [H]

COG id: COG1414

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 iclR-ED (iclR effector binding) domain [H]

Homologues:

Organism=Escherichia coli, GI145693096, Length=253, Percent_Identity=49.802371541502, Blast_Score=251, Evalue=4e-68,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014757
- InterPro:   IPR005471
- InterPro:   IPR011991 [H]

Pfam domain/function: PF09339 HTH_IclR; PF01614 IclR [H]

EC number: NA

Molecular weight: Translated: 28809; Mature: 28678

Theoretical pI: Translated: 9.07; Mature: 9.07

Prosite motif: PS51077 HTH_ICLR ; PS51078 ICLR_ED

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKYANVRGLSRGLQVLRALNAMENGRATSQQLSEATGLHRTTVRRLLETLVEEGFVRRS
CCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCHHHHHHHHHHHHHHHCCHHCCC
TSDDSFRLTLDVRALSEGFTDDERIATIAPPIMGRLLQRVVWPSDLTTPDGDAMIIRETT
CCCCCEEEEEEHHHHHCCCCCCCCCHHHCCHHHHHHHHHHHCCCCCCCCCCCEEEEECCC
HRFSPLSFHRSMVGRRLPILLTSAGRVYFSMCPDAEREDILEVLRSGAGGEQQLKLAMDD
CCCCHHHHHHHHHCCCCCEEEECCCCEEEEECCCCCHHHHHHHHHCCCCCHHHHHHHHHH
AYIRNLIRQTRKDGFGSNHGDWADQKKIGAVAVAIQAEGRVLASLNVVYLEQAISPAEAT
HHHHHHHHHHHHCCCCCCCCCCCHHHHHCCEEEEEECCCEEEHHHHHHHHHHHCCHHHHH
RRFVPELQQAAKEMVAALSA
HHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
TKYANVRGLSRGLQVLRALNAMENGRATSQQLSEATGLHRTTVRRLLETLVEEGFVRRS
CCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCHHHHHHHHHHHHHHHCCHHCCC
TSDDSFRLTLDVRALSEGFTDDERIATIAPPIMGRLLQRVVWPSDLTTPDGDAMIIRETT
CCCCCEEEEEEHHHHHCCCCCCCCCHHHCCHHHHHHHHHHHCCCCCCCCCCCEEEEECCC
HRFSPLSFHRSMVGRRLPILLTSAGRVYFSMCPDAEREDILEVLRSGAGGEQQLKLAMDD
CCCCHHHHHHHHHCCCCCEEEECCCCEEEEECCCCCHHHHHHHHHCCCCCHHHHHHHHHH
AYIRNLIRQTRKDGFGSNHGDWADQKKIGAVAVAIQAEGRVLASLNVVYLEQAISPAEAT
HHHHHHHHHHHHCCCCCCCCCCCHHHHHCCEEEEEECCCEEEHHHHHHHHHHHCCHHHHH
RRFVPELQQAAKEMVAALSA
HHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]