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The map label for this gene is qor [H]

Identifier: 73539951

GI number: 73539951

Start: 269737

End: 270717

Strand: Direct

Name: qor [H]

Synonym: Reut_A0245

Alternate gene names: 73539951

Gene position: 269737-270717 (Clockwise)

Preceding gene: 73539950

Following gene: 73539954

Centisome position: 7.09

GC content: 66.46

Gene sequence:

>981_bases
ATGCTGACCGCCCGCGTCATACGCGTCCACGAATTTGGCCCACCCGAAGCGATGCAGCTCGAGCGCATGGAGCTGCCACC
GCCCGCCGAAGGCGAGGTAGTGGTGCGCCAGACGGCGATGGGCTTTAACTTCATTGATATCTACCAGCGCCGCGGCACGT
ATCCCTTGCCACCGGGCACCGGCCTTGGCCATGAGGCCGCCGGCGTGGTCGAGGCAGTCGGTGCGGGCGTGAGGGGGTTT
GCGCCGGGCGACCGCGTGGCCTACATGAATGCGGGGCTTGGTGCCTATGCCGACTACCGCAACGTGCCGGCCGCGAAGCT
GGTACGCGTGCCGGACAGCATTTCCGACGAGCAGGCTGCCGCCGTCATCTTCAAGGGGATGACTGCGCAATACCTGGTGC
GCCATACCCATGCCGTGAAGGCGGGCGATGCGGTGCTGATCCATGCCGCCGCGGGCGGTGTGGGCCAGATACTGAGCAGC
TGGGCCAAGGCGCTGGGCGCCTATGTGATTGGCACTGCTGGCTCGCCGGAGAAGTGCGAACTCGCGCGCCGGATGGGCTG
TGACGTGGCCATCGACTATCGCAGCGGCGATTGGGTCAAGGCCGTACGCGAGGCCACCGGCGGACGTGGCGTGCGCGTCG
TATATGACGCGGTGGGCAAGGACACCTTTTTGGGCTCGCTCGATTGCGCGCAGCAGTTCGGCCTGGTGGTGCTGTACGGT
GCCGCGTCTGGCCCGGCGCCGGCGATCGAACCCGAACTGCTGAACAAGAAGGGTTGCCTGTTCCTGACGCGACCTTCGGT
GTTTCCGCACAACGCGGACCCGGATATGTTCCGCGCCAACGCGAAGGACCTGTTCGACGCCGTTACCGCCGGCCATGTGA
AGGTGGAGATCGGCGCGCGTTTCGCGCTGCAGGACGTTGCCAAAGCGCATGCCGCCGCAGAGTCCCGGGCGACGACCGGG
GCAATCGTATTGCTCCCGTAG

Upstream 100 bases:

>100_bases
TGCATGTGCTGCGACCTGACGTGATCGCTTGCGTCTGAGCCCGGGCACGTTTTCGCAAAACCGGAAATAATCGGGTCTTC
CCAGTCAGAGGAGACCCGGC

Downstream 100 bases:

>100_bases
TGTCGATCAGACTTGCTGCGTTGCGGACGCCGCGTGCCAGTGCTGGTCGCGGCAAACACTGATCTCCACCGTCACGTGCA
CGAGTTCCTCGTGCACGGAC

Product: zinc-containing alcohol dehydrogenase superfamily protein

Products: NA

Alternate protein names: NADPH:quinone reductase [H]

Number of amino acids: Translated: 326; Mature: 326

Protein sequence:

>326_residues
MLTARVIRVHEFGPPEAMQLERMELPPPAEGEVVVRQTAMGFNFIDIYQRRGTYPLPPGTGLGHEAAGVVEAVGAGVRGF
APGDRVAYMNAGLGAYADYRNVPAAKLVRVPDSISDEQAAAVIFKGMTAQYLVRHTHAVKAGDAVLIHAAAGGVGQILSS
WAKALGAYVIGTAGSPEKCELARRMGCDVAIDYRSGDWVKAVREATGGRGVRVVYDAVGKDTFLGSLDCAQQFGLVVLYG
AASGPAPAIEPELLNKKGCLFLTRPSVFPHNADPDMFRANAKDLFDAVTAGHVKVEIGARFALQDVAKAHAAAESRATTG
AIVLLP

Sequences:

>Translated_326_residues
MLTARVIRVHEFGPPEAMQLERMELPPPAEGEVVVRQTAMGFNFIDIYQRRGTYPLPPGTGLGHEAAGVVEAVGAGVRGF
APGDRVAYMNAGLGAYADYRNVPAAKLVRVPDSISDEQAAAVIFKGMTAQYLVRHTHAVKAGDAVLIHAAAGGVGQILSS
WAKALGAYVIGTAGSPEKCELARRMGCDVAIDYRSGDWVKAVREATGGRGVRVVYDAVGKDTFLGSLDCAQQFGLVVLYG
AASGPAPAIEPELLNKKGCLFLTRPSVFPHNADPDMFRANAKDLFDAVTAGHVKVEIGARFALQDVAKAHAAAESRATTG
AIVLLP
>Mature_326_residues
MLTARVIRVHEFGPPEAMQLERMELPPPAEGEVVVRQTAMGFNFIDIYQRRGTYPLPPGTGLGHEAAGVVEAVGAGVRGF
APGDRVAYMNAGLGAYADYRNVPAAKLVRVPDSISDEQAAAVIFKGMTAQYLVRHTHAVKAGDAVLIHAAAGGVGQILSS
WAKALGAYVIGTAGSPEKCELARRMGCDVAIDYRSGDWVKAVREATGGRGVRVVYDAVGKDTFLGSLDCAQQFGLVVLYG
AASGPAPAIEPELLNKKGCLFLTRPSVFPHNADPDMFRANAKDLFDAVTAGHVKVEIGARFALQDVAKAHAAAESRATTG
AIVLLP

Specific function: Unknown

COG id: COG0604

COG function: function code CR; NADPH:quinone reductase and related Zn-dependent oxidoreductases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily [H]

Homologues:

Organism=Homo sapiens, GI194239674, Length=327, Percent_Identity=29.6636085626911, Blast_Score=135, Evalue=4e-32,
Organism=Homo sapiens, GI13236495, Length=327, Percent_Identity=29.6636085626911, Blast_Score=135, Evalue=4e-32,
Organism=Homo sapiens, GI22538446, Length=326, Percent_Identity=30.3680981595092, Blast_Score=129, Evalue=3e-30,
Organism=Homo sapiens, GI22538444, Length=326, Percent_Identity=30.3680981595092, Blast_Score=129, Evalue=3e-30,
Organism=Homo sapiens, GI194239676, Length=210, Percent_Identity=34.7619047619048, Blast_Score=117, Evalue=1e-26,
Organism=Homo sapiens, GI24308257, Length=243, Percent_Identity=31.2757201646091, Blast_Score=112, Evalue=4e-25,
Organism=Homo sapiens, GI18379349, Length=318, Percent_Identity=26.7295597484277, Blast_Score=104, Evalue=1e-22,
Organism=Homo sapiens, GI28557745, Length=233, Percent_Identity=33.4763948497854, Blast_Score=97, Evalue=2e-20,
Organism=Homo sapiens, GI226059159, Length=245, Percent_Identity=27.7551020408163, Blast_Score=79, Evalue=8e-15,
Organism=Homo sapiens, GI226059133, Length=245, Percent_Identity=27.7551020408163, Blast_Score=79, Evalue=8e-15,
Organism=Homo sapiens, GI226056130, Length=245, Percent_Identity=27.7551020408163, Blast_Score=78, Evalue=9e-15,
Organism=Homo sapiens, GI67078404, Length=312, Percent_Identity=26.9230769230769, Blast_Score=77, Evalue=3e-14,
Organism=Homo sapiens, GI67078406, Length=280, Percent_Identity=27.1428571428571, Blast_Score=67, Evalue=2e-11,
Organism=Homo sapiens, GI47519420, Length=216, Percent_Identity=27.7777777777778, Blast_Score=67, Evalue=2e-11,
Organism=Homo sapiens, GI197927207, Length=189, Percent_Identity=25.9259259259259, Blast_Score=66, Evalue=5e-11,
Organism=Escherichia coli, GI1790485, Length=324, Percent_Identity=44.4444444444444, Blast_Score=271, Evalue=5e-74,
Organism=Escherichia coli, GI87081918, Length=206, Percent_Identity=28.6407766990291, Blast_Score=69, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI17507255, Length=204, Percent_Identity=29.4117647058824, Blast_Score=87, Evalue=8e-18,
Organism=Caenorhabditis elegans, GI17556000, Length=248, Percent_Identity=27.0161290322581, Blast_Score=67, Evalue=9e-12,
Organism=Caenorhabditis elegans, GI17536829, Length=317, Percent_Identity=25.2365930599369, Blast_Score=64, Evalue=1e-10,
Organism=Saccharomyces cerevisiae, GI6319520, Length=324, Percent_Identity=34.2592592592593, Blast_Score=184, Evalue=2e-47,
Organism=Saccharomyces cerevisiae, GI6323961, Length=257, Percent_Identity=26.8482490272374, Blast_Score=84, Evalue=4e-17,
Organism=Saccharomyces cerevisiae, GI6324486, Length=257, Percent_Identity=27.6264591439689, Blast_Score=81, Evalue=2e-16,
Organism=Saccharomyces cerevisiae, GI6323729, Length=253, Percent_Identity=25.296442687747, Blast_Score=79, Evalue=9e-16,
Organism=Drosophila melanogaster, GI45550423, Length=190, Percent_Identity=27.8947368421053, Blast_Score=71, Evalue=9e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013149
- InterPro:   IPR013154
- InterPro:   IPR002085
- InterPro:   IPR011032
- InterPro:   IPR016040
- InterPro:   IPR002364 [H]

Pfam domain/function: PF08240 ADH_N; PF00107 ADH_zinc_N [H]

EC number: =1.6.5.5 [H]

Molecular weight: Translated: 34322; Mature: 34322

Theoretical pI: Translated: 7.61; Mature: 7.61

Prosite motif: PS00059 ADH_ZINC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLTARVIRVHEFGPPEAMQLERMELPPPAEGEVVVRQTAMGFNFIDIYQRRGTYPLPPGT
CCCEEEEEEECCCCCHHHHHHHCCCCCCCCCCEEEEEECCCCCHHHHHHHCCCCCCCCCC
GLGHEAAGVVEAVGAGVRGFAPGDRVAYMNAGLGAYADYRNVPAAKLVRVPDSISDEQAA
CCCCHHHHHHHHHCCCCCCCCCCCEEEEEECCCCCCHHHCCCCHHHEEECCCCCCCHHHH
AVIFKGMTAQYLVRHTHAVKAGDAVLIHAAAGGVGQILSSWAKALGAYVIGTAGSPEKCE
HHHHCCCHHHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHHHHHCCEEEECCCCCHHHH
LARRMGCDVAIDYRSGDWVKAVREATGGRGVRVVYDAVGKDTFLGSLDCAQQFGLVVLYG
HHHHCCCCEEEECCCCHHHHHHHHHCCCCCEEEEEECCCCCCCCCCHHHHHHCCEEEEEE
AASGPAPAIEPELLNKKGCLFLTRPSVFPHNADPDMFRANAKDLFDAVTAGHVKVEIGAR
CCCCCCCCCCHHHCCCCCCEEEECCCCCCCCCCHHHHHCCHHHHHHHHHCCEEEEEECCH
FALQDVAKAHAAAESRATTGAIVLLP
HHHHHHHHHHHHHHCCCCCCEEEEEC
>Mature Secondary Structure
MLTARVIRVHEFGPPEAMQLERMELPPPAEGEVVVRQTAMGFNFIDIYQRRGTYPLPPGT
CCCEEEEEEECCCCCHHHHHHHCCCCCCCCCCEEEEEECCCCCHHHHHHHCCCCCCCCCC
GLGHEAAGVVEAVGAGVRGFAPGDRVAYMNAGLGAYADYRNVPAAKLVRVPDSISDEQAA
CCCCHHHHHHHHHCCCCCCCCCCCEEEEEECCCCCCHHHCCCCHHHEEECCCCCCCHHHH
AVIFKGMTAQYLVRHTHAVKAGDAVLIHAAAGGVGQILSSWAKALGAYVIGTAGSPEKCE
HHHHCCCHHHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHHHHHCCEEEECCCCCHHHH
LARRMGCDVAIDYRSGDWVKAVREATGGRGVRVVYDAVGKDTFLGSLDCAQQFGLVVLYG
HHHHCCCCEEEECCCCHHHHHHHHHCCCCCEEEEEECCCCCCCCCCHHHHHHCCEEEEEE
AASGPAPAIEPELLNKKGCLFLTRPSVFPHNADPDMFRANAKDLFDAVTAGHVKVEIGAR
CCCCCCCCCCHHHCCCCCCEEEECCCCCCCCCCHHHHHCCHHHHHHHHHCCEEEEEECCH
FALQDVAKAHAAAESRATTGAIVLLP
HHHHHHHHHHHHHHCCCCCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]