Click here to switch to the map view.

The map label for this gene is 73539926

Identifier: 73539926

GI number: 73539926

Start: 246309

End: 247331

Strand: Direct

Name: 73539926

Synonym: Reut_A0220

Alternate gene names: NA

Gene position: 246309-247331 (Clockwise)

Preceding gene: 73539925

Following gene: 73539927

Centisome position: 6.47

GC content: 67.35

Gene sequence:

>1023_bases
ATGCAGACCAGCAACGTCCTCATCGTCGGTGGCGCCGGGTTTATCGGCAGCCATCTAGCTTCCCGGCTGGCCGGTGCCGC
CTCGGCGTCCGGCGCGCCGCTTGAACCGGGCTCCAATCCAGATTCCCCCATCGCACCCGAACGCATCGTGATCGGCACGC
GCAACGTGGAGCATGCGCAGCATCTGCTGCTGTTGCCGCGTGTGGAGGTGGTGGAACTCGGTCTGGCCGACAATGCGGCG
CTCGACGATGCGATTGGCCCGCTCGGCACGGACGGCATTGTCGTCAACCTGGTCGGGGTGCTGCACGGCGAGCGTGGTGA
CCCGTACGGGCCCGAGTTCGCGGCTGCCCATGTCGAAATCGTCGAGCAGGTGGTGGGTTCGTGCCTGCGCACCGGCGTCC
GCCGGCTGCTCCATATGAGCGCGCTGGGCGCGGACAGCCGCGGTCCGTCGATGTATCAGCGCAGCAAGGGCGACGGCGAA
CGGCTGGTGCGCGACAGCGGCCTGGACTGGACTGTGTTCCGCCCCTCCGTAGTCTTTGGTCCCGACGACCACTTCCTCAA
CCTGTTCGCGCATATGCAGGAGATCGCGCCGGTGGTGCCGCTGGCCTGCGCGCATGCGCGCTTCCAGCCGATCTACGTAC
TGGATGTGGTGCAGGCCTTCGTCAACGCCATGGTTACGCCCGCGACCATCGGACATGGCTATGACCTCGGCGGCCCCACG
GTGTACACGCTGGAAGAACTGGTGCGCTTTGCGGGCCGCGCATCGGGACACCCGCGCCCGGTGATCGCATTGCCCGACGC
GCTGGCACGCGTGCAGGCCGCAGTGATGGAGCACATGCCGGGCGATACGCTGCTCTCGCGCGACAACCTCGATTCGATGC
AGTTCGACAACGTGCTGCACGGGCCCATGGCGAGCGAACTCGGCCTGCATCCGGTCGGGCTGGAAGCCGTGATGACAGAC
GTGCTGGCCGGGCGCACCCGTGATGCCCAGCTCACGGTCATGCGCGCGAGCGTGCATCGGTAG

Upstream 100 bases:

>100_bases
ACCACCAGCCTGCCGTGAACGCGTGCGCGCCCCGCCTTTCCGGGGCGCGTGCCATGGCCGGTCTGCCGCCACGTGCCGTT
TTCCTCGCACGGAGGCATCC

Downstream 100 bases:

>100_bases
CGGACCCGGCTCGCAACGCCGCGCTTGCTTCTATGTGATCGGGATTCGCAGCCGTTGCGAGTCCTTTTCACTTTGAGAGC
GAACGCCGCGCTGGCAAAAT

Product: NAD-dependent epimerase/dehydratase:3-beta hydroxysteroid dehydrogenase/isomerase:dTDP-4-dehydrorhamnose reductase

Products: NAD+; ubiquinol

Alternate protein names: NADH Dehydrogenase; NADH-Ubiquinone Oxidoreductase; 3-Beta Hydroxysteroid Dehydrogenase/Isomerase; Nucleoside-Diphosphate-Sugar Epimerase; Oxidoreductase; NADH-Ubiquinone Oxidoreductase Subunit; 3-Beta Hydroxysteroid Dehydrogenase/Isomerase Family; NADH-Ubiquinone Oxireductase; NADH Dehydrogenase/Oxidoreductase-Like Protein; NADH-Ubiquinone Oxidoreductase Family Protein; NAD-Dependent Epimerase/Dehydratase Family Protein; NAD Dependent Epimerase/Dehydratase Family; NAD Dependent Epimerase/Dehydratase Family Protein; 3-Beta-Hydroxy-Delta(5)-Steroid Dehydrogenase; NADH Ubiquinone Oxidoreductase; Oxidoreductase Protein; Nucleoside-Diphosphate-Sugar Epimerases; NADH Dehydrogenase 1 Alpha Subcomplex; Dehydrogenase; NmrA-Like Protein; NADH Dehydrogenase/NADH Dehydrogenase Protein; Ubiquinone Dependent NADH Dehydrogenase; NADH Dehydrogenase Subunit; Homolog NADH Dehydrogenase; NADH Dehydrogenase-Like Protein; NAD Dependent Epimerase; Nucleoside-Diphosphate Sugar Epimerase; NADH-Ubiquinone Oxidoreductase -Like Protein; NADH-Ubiquinone Oxidoreductase Putativ; NADH-Quinone Oxidoreductase; Nucleoside-Diphosphate-Sugar Epimerase Protein; LOW QUALITY PROTEIN Oxidoreductase

Number of amino acids: Translated: 340; Mature: 340

Protein sequence:

>340_residues
MQTSNVLIVGGAGFIGSHLASRLAGAASASGAPLEPGSNPDSPIAPERIVIGTRNVEHAQHLLLLPRVEVVELGLADNAA
LDDAIGPLGTDGIVVNLVGVLHGERGDPYGPEFAAAHVEIVEQVVGSCLRTGVRRLLHMSALGADSRGPSMYQRSKGDGE
RLVRDSGLDWTVFRPSVVFGPDDHFLNLFAHMQEIAPVVPLACAHARFQPIYVLDVVQAFVNAMVTPATIGHGYDLGGPT
VYTLEELVRFAGRASGHPRPVIALPDALARVQAAVMEHMPGDTLLSRDNLDSMQFDNVLHGPMASELGLHPVGLEAVMTD
VLAGRTRDAQLTVMRASVHR

Sequences:

>Translated_340_residues
MQTSNVLIVGGAGFIGSHLASRLAGAASASGAPLEPGSNPDSPIAPERIVIGTRNVEHAQHLLLLPRVEVVELGLADNAA
LDDAIGPLGTDGIVVNLVGVLHGERGDPYGPEFAAAHVEIVEQVVGSCLRTGVRRLLHMSALGADSRGPSMYQRSKGDGE
RLVRDSGLDWTVFRPSVVFGPDDHFLNLFAHMQEIAPVVPLACAHARFQPIYVLDVVQAFVNAMVTPATIGHGYDLGGPT
VYTLEELVRFAGRASGHPRPVIALPDALARVQAAVMEHMPGDTLLSRDNLDSMQFDNVLHGPMASELGLHPVGLEAVMTD
VLAGRTRDAQLTVMRASVHR
>Mature_340_residues
MQTSNVLIVGGAGFIGSHLASRLAGAASASGAPLEPGSNPDSPIAPERIVIGTRNVEHAQHLLLLPRVEVVELGLADNAA
LDDAIGPLGTDGIVVNLVGVLHGERGDPYGPEFAAAHVEIVEQVVGSCLRTGVRRLLHMSALGADSRGPSMYQRSKGDGE
RLVRDSGLDWTVFRPSVVFGPDDHFLNLFAHMQEIAPVVPLACAHARFQPIYVLDVVQAFVNAMVTPATIGHGYDLGGPT
VYTLEELVRFAGRASGHPRPVIALPDALARVQAAVMEHMPGDTLLSRDNLDSMQFDNVLHGPMASELGLHPVGLEAVMTD
VLAGRTRDAQLTVMRASVHR

Specific function: Unknown

COG id: COG0702

COG function: function code MG; Predicted nucleoside-diphosphate-sugar epimerases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI6681764, Length=235, Percent_Identity=30.2127659574468, Blast_Score=103, Evalue=2e-22,
Organism=Caenorhabditis elegans, GI17556106, Length=257, Percent_Identity=26.0700389105058, Blast_Score=71, Evalue=8e-13,
Organism=Drosophila melanogaster, GI24667554, Length=256, Percent_Identity=28.125, Blast_Score=90, Evalue=3e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 1.6.5.3; 1.6.99.3

Molecular weight: Translated: 36036; Mature: 36036

Theoretical pI: Translated: 5.81; Mature: 5.81

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQTSNVLIVGGAGFIGSHLASRLAGAASASGAPLEPGSNPDSPIAPERIVIGTRNVEHAQ
CCCCCEEEEECCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCEEEEECCCHHHHH
HLLLLPRVEVVELGLADNAALDDAIGPLGTDGIVVNLVGVLHGERGDPYGPEFAAAHVEI
HHHHCCCCEEEEECCCCCCCHHHHCCCCCCCHHHHHHHHHHCCCCCCCCCCHHHHHHHHH
VEQVVGSCLRTGVRRLLHMSALGADSRGPSMYQRSKGDGERLVRDSGLDWTVFRPSVVFG
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHCCCCHHHHHHHCCCCEEEECCEEEEC
PDDHFLNLFAHMQEIAPVVPLACAHARFQPIYVLDVVQAFVNAMVTPATIGHGYDLGGPT
CCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCH
VYTLEELVRFAGRASGHPRPVIALPDALARVQAAVMEHMPGDTLLSRDNLDSMQFDNVLH
HHHHHHHHHHHHCCCCCCCCEEECCHHHHHHHHHHHHHCCCCCEECCCCCCHHHHHHHHC
GPMASELGLHPVGLEAVMTDVLAGRTRDAQLTVMRASVHR
CCCHHHCCCCCCCHHHHHHHHHHCCCCCCEEEEEECCCCC
>Mature Secondary Structure
MQTSNVLIVGGAGFIGSHLASRLAGAASASGAPLEPGSNPDSPIAPERIVIGTRNVEHAQ
CCCCCEEEEECCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCEEEEECCCHHHHH
HLLLLPRVEVVELGLADNAALDDAIGPLGTDGIVVNLVGVLHGERGDPYGPEFAAAHVEI
HHHHCCCCEEEEECCCCCCCHHHHCCCCCCCHHHHHHHHHHCCCCCCCCCCHHHHHHHHH
VEQVVGSCLRTGVRRLLHMSALGADSRGPSMYQRSKGDGERLVRDSGLDWTVFRPSVVFG
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHCCCCHHHHHHHCCCCEEEECCEEEEC
PDDHFLNLFAHMQEIAPVVPLACAHARFQPIYVLDVVQAFVNAMVTPATIGHGYDLGGPT
CCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCH
VYTLEELVRFAGRASGHPRPVIALPDALARVQAAVMEHMPGDTLLSRDNLDSMQFDNVLH
HHHHHHHHHHHHCCCCCCCCEEECCHHHHHHHHHHHHHCCCCCEECCCCCCHHHHHHHHC
GPMASELGLHPVGLEAVMTDVLAGRTRDAQLTVMRASVHR
CCCHHHCCCCCCCHHHHHHHHHHCCCCCCEEEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NADH; H+; ubiquinone

Specific reaction: NADH + H+ + ubiquinone = NAD+ + ubiquinol

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA