| Definition | Ralstonia eutropha JMP134 chromosome 1, complete sequence. |
|---|---|
| Accession | NC_007347 |
| Length | 3,806,533 |
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The map label for this gene is slt [H]
Identifier: 73539925
GI number: 73539925
Start: 244265
End: 246226
Strand: Direct
Name: slt [H]
Synonym: Reut_A0219
Alternate gene names: 73539925
Gene position: 244265-246226 (Clockwise)
Preceding gene: 73539923
Following gene: 73539926
Centisome position: 6.42
GC content: 65.65
Gene sequence:
>1962_bases ATGCTGAAGGCAGTATATCTGCGGCGTGCTGGGCAGGCCGCATCGGTCGCCGTGGCGTGTGCCGTGCTTTCCACCCCCGC GCTCGCGCAAAAGCGCCCGCAGCAGCAGGCTGCGCCGCGCGTGCAGGCCGCGCCGGTGATCCCGTCCGATCCCGACGACG CATTCGTTGCGCTGCGCGAAGCCGCGCGCAAGAACGACGTCGAGCGTGCGTACGCCATTTCGGCGACGCTGGTCGACTAC CCGATCCCGTCGTACGTCGAATATTTCCGCATCAAGCCGCAGATGTTCGACGGCAGCGGACTGGCTCGCATCGATGCGCC GGACGACCAGGTGCGCGCGTTCCTGCAACGCTACAAGGGTCAGGCCATTGCCGACCGCATGCGCAACGACTGGCTGCTGG TGCTCGGCAAGAAGCGCGACTGGGCCAACTTTGATGCGGAGTATCCGCAGTTCGTGCTCAAGGACGACACGCAGGTCGAG TGCTACGCGCTGCTGTCGCGCGCGCTCAAGGGGCAGAATGTGGCGGCCGATACGCGCAACGTGCTCAGCGATGTGCGCTA CTACGGCGAAGGCTGCGTCGACCTGATCGGCTATCTCGTGCAGAGCCAGCAGATCCAGCGCAGCGATGTCGCGTTCCAGG CGCGCCAGGCGCTGGAACAGAACCTCGTCACGCTGGCCGGCAGGATCGCGGCCACAGTGCCCGATGCGCGCGTGGACAGC GACACGCTGGCGACTATCGTCAAGATGGCGCGCAATGATCCGTCGCAGGCCGTGGCCTATCTGACAGCAAGCGGCGGCAG CCTGTCGCGCGATGAACAGGGTGCGGCTTGGGGAGTGATCGGTCAGTACGCGGCCAAGAAGCTGTTGCCCGATGCCGCCT TCTACTACCGCCGCCAGATGGACCTGGGCGGCAACCAGTGGATGTCGGACGAGTCGCAGGAGTGGCGCGTGCGCGCGGCG CTGCGGCAGGGCGACTGGAAGCAGGTGCGCCAGGCCATCGAGATGATGCGGCCCGAATTGCGCGCCAAGGACCCGGCCTG GACCTATTGGTACGGCCGCTCGCTGAAGGCGGATGGCCGCGACGCCGAGGCACAGCAGCAGTACCAGCAGATCGCGGGCC AGTTCAATTTCTATGGCCAGCTCGCCAGCGAAGAACTCGGCAACCGCATCACGCTGCCGGCGCGCACCACTGTGAGCGAT GCCGAGGCCATGACCATGCGCAGCCGTGCGGGCTTCCAGCGCGCGCAGAAGCTCTACAACATGAACCTGCGTTTCGAAGG CACGCGGGAATGGAACTGGGAACTGCGCGGCATGAGCGACCGCGAGCTGCTGGCTGCGGCCGAGTACGCACGCCGCGTCG AATTGCTGGACCGCACCGTCAACACGGCGGACCGCACGCGCGCCGAGCATGACTTCTCGCTACGCTTCCCGATGCCGTAT CGCGACCTCATGCAGCGCGCGACCGACGATGTCGGCCTCGACATGGCATGGGCCTACGGCCTGATCCGCCAGGAATCGCG CTTCATCATGAGTGCGCGTTCGTCGGCGGGCGCGCATGGGCTGATGCAGGTGATGCCGGCGACGGCAAAGTACGTGGCGC GCAAGATCGGCATGGCCGACTTCTCGCCATCGATGATGGGTGATCCCAACATCAACATCGTGCTGGGCACCAATTACCTG AGCATGGTGCTGACTGATCTCGACAGCTCGTGGACGCTGGCGTCGGCCGCTTACAACGCCGGTCCGGGGCGGCCCAAGGC CTGGCGCAGTACGCTGACGCGGCCGGTCGAAGGCGCGATCTTCGCCGAGACCATTCCGTTCAACGAAACGCGCACGTACG TGAAGAATGTGCTTTCCAACGCTACGTACTATGCTGCATTGATGAGCGGCCAGCCTCAGTCACTGAAGTCGCGCCTGGGC CAGGTTGCACCGTCGGCGGTGACCACCACCAGCCTGCCGTGA
Upstream 100 bases:
>100_bases GGCTGACATGGCGTGGGATAATGCCTGCAATCAAACCAATAATTGACGGTGGCAGCGTGCAAAGCTGGCGCCGTCTGACG TCACAATAAGGAAGCTAAGA
Downstream 100 bases:
>100_bases ACGCGTGCGCGCCCCGCCTTTCCGGGGCGCGTGCCATGGCCGGTCTGCCGCCACGTGCCGTTTTCCTCGCACGGAGGCAT CCATGCAGACCAGCAACGTC
Product: lytic transglycosylase, catalytic
Products: 1,6-Anhydrobond [C]
Alternate protein names: Exomuramidase; Peptidoglycan lytic exotransglycosylase; Slt70 [H]
Number of amino acids: Translated: 653; Mature: 653
Protein sequence:
>653_residues MLKAVYLRRAGQAASVAVACAVLSTPALAQKRPQQQAAPRVQAAPVIPSDPDDAFVALREAARKNDVERAYAISATLVDY PIPSYVEYFRIKPQMFDGSGLARIDAPDDQVRAFLQRYKGQAIADRMRNDWLLVLGKKRDWANFDAEYPQFVLKDDTQVE CYALLSRALKGQNVAADTRNVLSDVRYYGEGCVDLIGYLVQSQQIQRSDVAFQARQALEQNLVTLAGRIAATVPDARVDS DTLATIVKMARNDPSQAVAYLTASGGSLSRDEQGAAWGVIGQYAAKKLLPDAAFYYRRQMDLGGNQWMSDESQEWRVRAA LRQGDWKQVRQAIEMMRPELRAKDPAWTYWYGRSLKADGRDAEAQQQYQQIAGQFNFYGQLASEELGNRITLPARTTVSD AEAMTMRSRAGFQRAQKLYNMNLRFEGTREWNWELRGMSDRELLAAAEYARRVELLDRTVNTADRTRAEHDFSLRFPMPY RDLMQRATDDVGLDMAWAYGLIRQESRFIMSARSSAGAHGLMQVMPATAKYVARKIGMADFSPSMMGDPNINIVLGTNYL SMVLTDLDSSWTLASAAYNAGPGRPKAWRSTLTRPVEGAIFAETIPFNETRTYVKNVLSNATYYAALMSGQPQSLKSRLG QVAPSAVTTTSLP
Sequences:
>Translated_653_residues MLKAVYLRRAGQAASVAVACAVLSTPALAQKRPQQQAAPRVQAAPVIPSDPDDAFVALREAARKNDVERAYAISATLVDY PIPSYVEYFRIKPQMFDGSGLARIDAPDDQVRAFLQRYKGQAIADRMRNDWLLVLGKKRDWANFDAEYPQFVLKDDTQVE CYALLSRALKGQNVAADTRNVLSDVRYYGEGCVDLIGYLVQSQQIQRSDVAFQARQALEQNLVTLAGRIAATVPDARVDS DTLATIVKMARNDPSQAVAYLTASGGSLSRDEQGAAWGVIGQYAAKKLLPDAAFYYRRQMDLGGNQWMSDESQEWRVRAA LRQGDWKQVRQAIEMMRPELRAKDPAWTYWYGRSLKADGRDAEAQQQYQQIAGQFNFYGQLASEELGNRITLPARTTVSD AEAMTMRSRAGFQRAQKLYNMNLRFEGTREWNWELRGMSDRELLAAAEYARRVELLDRTVNTADRTRAEHDFSLRFPMPY RDLMQRATDDVGLDMAWAYGLIRQESRFIMSARSSAGAHGLMQVMPATAKYVARKIGMADFSPSMMGDPNINIVLGTNYL SMVLTDLDSSWTLASAAYNAGPGRPKAWRSTLTRPVEGAIFAETIPFNETRTYVKNVLSNATYYAALMSGQPQSLKSRLG QVAPSAVTTTSLP >Mature_653_residues MLKAVYLRRAGQAASVAVACAVLSTPALAQKRPQQQAAPRVQAAPVIPSDPDDAFVALREAARKNDVERAYAISATLVDY PIPSYVEYFRIKPQMFDGSGLARIDAPDDQVRAFLQRYKGQAIADRMRNDWLLVLGKKRDWANFDAEYPQFVLKDDTQVE CYALLSRALKGQNVAADTRNVLSDVRYYGEGCVDLIGYLVQSQQIQRSDVAFQARQALEQNLVTLAGRIAATVPDARVDS DTLATIVKMARNDPSQAVAYLTASGGSLSRDEQGAAWGVIGQYAAKKLLPDAAFYYRRQMDLGGNQWMSDESQEWRVRAA LRQGDWKQVRQAIEMMRPELRAKDPAWTYWYGRSLKADGRDAEAQQQYQQIAGQFNFYGQLASEELGNRITLPARTTVSD AEAMTMRSRAGFQRAQKLYNMNLRFEGTREWNWELRGMSDRELLAAAEYARRVELLDRTVNTADRTRAEHDFSLRFPMPY RDLMQRATDDVGLDMAWAYGLIRQESRFIMSARSSAGAHGLMQVMPATAKYVARKIGMADFSPSMMGDPNINIVLGTNYL SMVLTDLDSSWTLASAAYNAGPGRPKAWRSTLTRPVEGAIFAETIPFNETRTYVKNVLSNATYYAALMSGQPQSLKSRLG QVAPSAVTTTSLP
Specific function: Murein-degrading enzyme. Catalyzes the cleavage of the glycosidic bonds between N-acetylmuramic acid and N- acetylglucosamine residues in peptidoglycan. May play a role in recycling of muropeptides during cell elongation and/or cell division [H]
COG id: COG0741
COG function: function code M; Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains)
Gene ontology:
Cell location: Periplasm. Note=Tightly associated with the murein sacculus (By similarity) [H]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the transglycosylase slt family [H]
Homologues:
Organism=Escherichia coli, GI87082441, Length=591, Percent_Identity=25.5499153976311, Blast_Score=167, Evalue=1e-42,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR016026 - InterPro: IPR008258 - InterPro: IPR012289 - InterPro: IPR008939 - InterPro: IPR000189 [H]
Pfam domain/function: PF01464 SLT [H]
EC number: 3.2.1.- [C]
Molecular weight: Translated: 72932; Mature: 72932
Theoretical pI: Translated: 9.38; Mature: 9.38
Prosite motif: PS00013 PROKAR_LIPOPROTEIN
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.5 %Cys (Translated Protein) 3.5 %Met (Translated Protein) 4.0 %Cys+Met (Translated Protein) 0.5 %Cys (Mature Protein) 3.5 %Met (Mature Protein) 4.0 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MLKAVYLRRAGQAASVAVACAVLSTPALAQKRPQQQAAPRVQAAPVIPSDPDDAFVALRE CCCHHHHHHCCCHHHHHHHHHHHCCCHHHHCCCHHHHCCCCEECCCCCCCCCHHHHHHHH AARKNDVERAYAISATLVDYPIPSYVEYFRIKPQMFDGSGLARIDAPDDQVRAFLQRYKG HHHHCCHHHHHHHHHHHCCCCCHHHHHHHHCCCEEECCCCEEEECCCHHHHHHHHHHHCC QAIADRMRNDWLLVLGKKRDWANFDAEYPQFVLKDDTQVECYALLSRALKGQNVAADTRN HHHHHHHCCCEEEEEECCCCCCCCCCCCCCEEECCCCCHHHHHHHHHHHCCCCCHHHHHH VLSDVRYYGEGCVDLIGYLVQSQQIQRSDVAFQARQALEQNLVTLAGRIAATVPDARVDS HHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCH DTLATIVKMARNDPSQAVAYLTASGGSLSRDEQGAAWGVIGQYAAKKLLPDAAFYYRRQM HHHHHHHHHHCCCHHHEEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHH DLGGNQWMSDESQEWRVRAALRQGDWKQVRQAIEMMRPELRAKDPAWTYWYGRSLKADGR CCCCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHCHHHCCCCCCEEEEECCCCCCCCC DAEAQQQYQQIAGQFNFYGQLASEELGNRITLPARTTVSDAEAMTMRSRAGFQRAQKLYN CHHHHHHHHHHHHCHHHHHHHHHHHHCCEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHC MNLRFEGTREWNWELRGMSDRELLAAAEYARRVELLDRTVNTADRTRAEHDFSLRFPMPY CCEEEECCCCCCEEECCCCHHHHHHHHHHHHHHHHHHHHHCHHHHHCCCCCCEEECCCCH RDLMQRATDDVGLDMAWAYGLIRQESRFIMSARSSAGAHGLMQVMPATAKYVARKIGMAD HHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCC FSPSMMGDPNINIVLGTNYLSMVLTDLDSSWTLASAAYNAGPGRPKAWRSTLTRPVEGAI CCCCCCCCCCEEEEECCHHHHHHHHHCCCCCCHHHHHCCCCCCCCHHHHHHHCCCCCCCE FAETIPFNETRTYVKNVLSNATYYAALMSGQPQSLKSRLGQVAPSAVTTTSLP EEECCCCCHHHHHHHHHHCCCCEEEHHHCCCCHHHHHHHHHCCCCCCCCCCCC >Mature Secondary Structure MLKAVYLRRAGQAASVAVACAVLSTPALAQKRPQQQAAPRVQAAPVIPSDPDDAFVALRE CCCHHHHHHCCCHHHHHHHHHHHCCCHHHHCCCHHHHCCCCEECCCCCCCCCHHHHHHHH AARKNDVERAYAISATLVDYPIPSYVEYFRIKPQMFDGSGLARIDAPDDQVRAFLQRYKG HHHHCCHHHHHHHHHHHCCCCCHHHHHHHHCCCEEECCCCEEEECCCHHHHHHHHHHHCC QAIADRMRNDWLLVLGKKRDWANFDAEYPQFVLKDDTQVECYALLSRALKGQNVAADTRN HHHHHHHCCCEEEEEECCCCCCCCCCCCCCEEECCCCCHHHHHHHHHHHCCCCCHHHHHH VLSDVRYYGEGCVDLIGYLVQSQQIQRSDVAFQARQALEQNLVTLAGRIAATVPDARVDS HHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCH DTLATIVKMARNDPSQAVAYLTASGGSLSRDEQGAAWGVIGQYAAKKLLPDAAFYYRRQM HHHHHHHHHHCCCHHHEEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHH DLGGNQWMSDESQEWRVRAALRQGDWKQVRQAIEMMRPELRAKDPAWTYWYGRSLKADGR CCCCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHCHHHCCCCCCEEEEECCCCCCCCC DAEAQQQYQQIAGQFNFYGQLASEELGNRITLPARTTVSDAEAMTMRSRAGFQRAQKLYN CHHHHHHHHHHHHCHHHHHHHHHHHHCCEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHC MNLRFEGTREWNWELRGMSDRELLAAAEYARRVELLDRTVNTADRTRAEHDFSLRFPMPY CCEEEECCCCCCEEECCCCHHHHHHHHHHHHHHHHHHHHHCHHHHHCCCCCCEEECCCCH RDLMQRATDDVGLDMAWAYGLIRQESRFIMSARSSAGAHGLMQVMPATAKYVARKIGMAD HHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCC FSPSMMGDPNINIVLGTNYLSMVLTDLDSSWTLASAAYNAGPGRPKAWRSTLTRPVEGAI CCCCCCCCCCEEEEECCHHHHHHHHHCCCCCCHHHHHCCCCCCCCHHHHHHHCCCCCCCE FAETIPFNETRTYVKNVLSNATYYAALMSGQPQSLKSRLGQVAPSAVTTTSLP EEECCCCCHHHHHHHHHHCCCCEEEHHHCCCCHHHHHHHHHCCCCCCCCCCCC
PDB accession: NA
Resolution: NA
Structure class: Unstructured
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: Muramic Acid Residue (N-Acetylmuramic Acid And N-Acetylglucosamine Residues) [C]
Specific reaction: Cleavage Of The Beta-1,4-Glycosidic Bond Between N-Acetylmuramic Acid And N-Acetylglucosamine Residues, Thereby Conserving The Energy In A Newly Synthesized 1,6-Anhydrobond In The Muramic Acid Residue. [C]
General reaction: Cleavage Of The Beta-1,4-Glycosidic Bond [C]
Inhibitor: NA
Structure determination priority: 9.0
TargetDB status: NA
Availability: NA
References: 11206551; 11258796 [H]