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The map label for this gene is nahR [H]

Identifier: 73539881

GI number: 73539881

Start: 201379

End: 202314

Strand: Reverse

Name: nahR [H]

Synonym: Reut_A0175

Alternate gene names: 73539881

Gene position: 202314-201379 (Counterclockwise)

Preceding gene: 73539883

Following gene: 73539879

Centisome position: 5.31

GC content: 68.48

Gene sequence:

>936_bases
ATGAATAGCCTACGCGGAATCGACCTGAACCTGCTGGTGGTGCTGGAAGCACTGCTGGCCGAACGCCATATCTCCCGGGC
CGCGCTGCGCCTGCACCTGAGCCAGCCGGCGGTCAGTCACGCGCTGGGACGGCTGCGGCAATTGCTGGACGACCCCATCC
TCGTACGCGGCAAGGGTGGACTGGTGCCGAGCGCCCGCGCCCATGAAATCGCCGGGCCGCTGGCAGAAGCGCTCGCGCAG
GTGCGCATCCTGTTGGGGCCCGGCGGTTTCCAGCCCGCCACGGCGCGCCGCACGTTCCGACTGGCGATGTCGGATTACGG
CGCGCTGGTGGTGCTGCCGCGGCTGTTGCGCGCGGTGCGAAAGGCGGCGCCGAATATCGATCTCGTCGTCACGCAGGCCA
GCCGCGAAGCCATGACGGCACAGGTGGCCGATGGCGAGATCGACATGGCGCTGGGCGTCTTCGCGCACCAGCCGGAAGGC
GTGCATGCCACGGCCCTGTTCGAGGAAAGCTACGCCTGCGCCGTCGATGCGGCAACCGTGCGCGATAACGGCAAGCTGGA
CCAGGTGGCTTACCTCGCGCGTTCACACGTGCTGGTGGCCACGCACAGCGAGCGCGTCGATGCCATCGATGCGGCTGTGG
CGAAGATTGGCGGAAGGCGCAAGATCGCTTGCGTGGTGCCGCACTGGAGCGTGGCGCCTGCATTGATCGCCGGCACCAAC
CTGGTCCTGACCACGGCACGCCGCAGCCTGGCGGCACTGGAAGCGGACCCGCGCTACGCGGTGTTCGATCCGCCGTTCCC
GCTGGACGACTTCACCTTCACCATGATCTGGCACGACCGCACCGAGGCCGACCCAGGCCACACCTGGCTGCGCGAACGCG
TGCAGGCCGCGGCAGCGACTCAGGAATCGGACGAGCCGATCAGCTTGCGCGGCTGA

Upstream 100 bases:

>100_bases
TGACATGGCGCACTCCGTAAGGCAATATTCGATGCCTGACAGTGTGAAATATCGCAGAATGAATTTCCAATTCTGCTTTC
ATACGTTTAACATTCGCCGA

Downstream 100 bases:

>100_bases
CGCGGAGGCGTCGACTTGCCGCTGGTCTGTGGCGGACCGGACTTTCGCACGGTGCCTTTGCCGCGCGGCGGCGGCTGTGA
ACCCGTGCCGCCACGGAATA

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 311; Mature: 311

Protein sequence:

>311_residues
MNSLRGIDLNLLVVLEALLAERHISRAALRLHLSQPAVSHALGRLRQLLDDPILVRGKGGLVPSARAHEIAGPLAEALAQ
VRILLGPGGFQPATARRTFRLAMSDYGALVVLPRLLRAVRKAAPNIDLVVTQASREAMTAQVADGEIDMALGVFAHQPEG
VHATALFEESYACAVDAATVRDNGKLDQVAYLARSHVLVATHSERVDAIDAAVAKIGGRRKIACVVPHWSVAPALIAGTN
LVLTTARRSLAALEADPRYAVFDPPFPLDDFTFTMIWHDRTEADPGHTWLRERVQAAAATQESDEPISLRG

Sequences:

>Translated_311_residues
MNSLRGIDLNLLVVLEALLAERHISRAALRLHLSQPAVSHALGRLRQLLDDPILVRGKGGLVPSARAHEIAGPLAEALAQ
VRILLGPGGFQPATARRTFRLAMSDYGALVVLPRLLRAVRKAAPNIDLVVTQASREAMTAQVADGEIDMALGVFAHQPEG
VHATALFEESYACAVDAATVRDNGKLDQVAYLARSHVLVATHSERVDAIDAAVAKIGGRRKIACVVPHWSVAPALIAGTN
LVLTTARRSLAALEADPRYAVFDPPFPLDDFTFTMIWHDRTEADPGHTWLRERVQAAAATQESDEPISLRG
>Mature_311_residues
MNSLRGIDLNLLVVLEALLAERHISRAALRLHLSQPAVSHALGRLRQLLDDPILVRGKGGLVPSARAHEIAGPLAEALAQ
VRILLGPGGFQPATARRTFRLAMSDYGALVVLPRLLRAVRKAAPNIDLVVTQASREAMTAQVADGEIDMALGVFAHQPEG
VHATALFEESYACAVDAATVRDNGKLDQVAYLARSHVLVATHSERVDAIDAAVAKIGGRRKIACVVPHWSVAPALIAGTN
LVLTTARRSLAALEADPRYAVFDPPFPLDDFTFTMIWHDRTEADPGHTWLRERVQAAAATQESDEPISLRG

Specific function: Regulates the expression of the naphthalene (nahA-F) and salicylate (nahG-M) metabolism genes [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI87081684, Length=298, Percent_Identity=26.1744966442953, Blast_Score=103, Evalue=1e-23,
Organism=Escherichia coli, GI1790147, Length=302, Percent_Identity=23.1788079470199, Blast_Score=85, Evalue=7e-18,

Paralogues:

None

Copy number: 825 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 33495; Mature: 33495

Theoretical pI: Translated: 7.41; Mature: 7.41

Prosite motif: PS50931 HTH_LYSR ; PS00092 N6_MTASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNSLRGIDLNLLVVLEALLAERHISRAALRLHLSQPAVSHALGRLRQLLDDPILVRGKGG
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHEECCCHHHHHHHHHHHHHHCCCEEEEECCC
LVPSARAHEIAGPLAEALAQVRILLGPGGFQPATARRTFRLAMSDYGALVVLPRLLRAVR
CCCCCCHHHHHHHHHHHHHHEEEEECCCCCCCCHHHHHEEEHHHCCCHHHHHHHHHHHHH
KAAPNIDLVVTQASREAMTAQVADGEIDMALGVFAHQPEGVHATALFEESYACAVDAATV
HHCCCCEEEEEECCCHHHEEEECCCCEEEEEHHEECCCCCCEEEEEECCCCEEEEECEEE
RDNGKLDQVAYLARSHVLVATHSERVDAIDAAVAKIGGRRKIACVVPHWSVAPALIAGTN
CCCCCHHHHHHHHHCEEEEEECCCHHHHHHHHHHHCCCCCEEEEEECCCCCCHHHHHCCC
LVLTTARRSLAALEADPRYAVFDPPFPLDDFTFTMIWHDRTEADPGHTWLRERVQAAAAT
EEEEHHHHHHHHHCCCCCEEEECCCCCCCCCEEEEEEECCCCCCCCHHHHHHHHHHHHHC
QESDEPISLRG
CCCCCCEECCC
>Mature Secondary Structure
MNSLRGIDLNLLVVLEALLAERHISRAALRLHLSQPAVSHALGRLRQLLDDPILVRGKGG
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHEECCCHHHHHHHHHHHHHHCCCEEEEECCC
LVPSARAHEIAGPLAEALAQVRILLGPGGFQPATARRTFRLAMSDYGALVVLPRLLRAVR
CCCCCCHHHHHHHHHHHHHHEEEEECCCCCCCCHHHHHEEEHHHCCCHHHHHHHHHHHHH
KAAPNIDLVVTQASREAMTAQVADGEIDMALGVFAHQPEGVHATALFEESYACAVDAATV
HHCCCCEEEEEECCCHHHEEEECCCCEEEEEHHEECCCCCCEEEEEECCCCEEEEECEEE
RDNGKLDQVAYLARSHVLVATHSERVDAIDAAVAKIGGRRKIACVVPHWSVAPALIAGTN
CCCCCHHHHHHHHHCEEEEEECCCHHHHHHHHHHHCCCCCEEEEEECCCCCCHHHHHCCC
LVLTTARRSLAALEADPRYAVFDPPFPLDDFTFTMIWHDRTEADPGHTWLRERVQAAAAT
EEEEHHHHHHHHHCCCCCEEEECCCCCCCCCEEEEEEECCCCCCCCHHHHHHHHHHHHHC
QESDEPISLRG
CCCCCCEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2703465; 2848005 [H]