BacMap

Definition	Ralstonia eutropha JMP134 chromosome chromosome 2, complete sequence.
Accession	NC_007348
Length	2,726,152

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The map label for this gene is dmpC [H]

Identifier: 73539511

GI number: 73539511

Start: 2519447

End: 2520901

Strand: Direct

Name: dmpC [H]

Synonym: Reut_B5689

Alternate gene names: 73539511

Gene position: 2519447-2520901 (Clockwise)

Preceding gene: 73539510

Following gene: 73539512

Centisome position: 92.42

GC content: 66.94

Gene sequence:

>1455_bases
GTGAAGCAATTCCGCAATTTCATCAATGGCGAGTTCGTCGCCACCAACAAGACCTTTGAGAACCGCGCGCCAGTGGATAA
CCGGGTAATCGGGCGCGTGCACGAGGCGGGGCAGGCTGAGGTGGATGCCGCCGTTGCCGCCGCGCGCGCCGCGCTGCATG
GCGACTGGGGGCGCATGCCGGTAGCCCGGCGCGTTGAACTGCTGCATGCCGTGGCCGACGAGATCAATCGTCGCTTCGAC
GATTTCCTCGAAGCCGAGCTGGCCGACACCGGCAAGCCGCGCAGCCTCGCCGCGCATATCGACATCCCGCGCGGCGCCGC
CAACTTCAAGGTCTTCGCCGACATCGTCAAGAACGCACCCACCGAAAGCTTCGAGATGACCACGCCGGACGGTGGCACGG
CGATCAGTTACGCGCTGCGCGCCCCGCTGGGCGTGGTGGCGGTGGTCTGCCCGTGGAACCTGCCGCTGCTGCTCATGACG
TGGAAGGTGGGCCCCGCGCTGGCCTGCGGCAACACGGTGATCGTCAAGCCTTCCGAGGAGACGCCGGCCACGGCCACGCT
GCTGGGCGAGGTGATGGAGAAGGTCGGCGTGCCAAAAGGCGTCTACAACGTGCTGCACGGCTTTGGTCCGGGCTCGGCGG
GCGAGTTCCTGACACGCCATCCCGGCGTCAACGGCATTACATTCACCGGCGAGACGCGCACTGGCGAGGCCATCATGGCC
GCGGCGGCAAAGGGCGTGCGGCCGGTCAGCTTCGAGCTTGGCGGCAAGAACGCGGGCATCGTTTTTGCCGATGCCGACTT
CGACAAGGCCGTGGCCGGCATCGCGCGCAGCGCGTTTGAGAACTGCGGGCAGGTCTGCCTGGGCACCGAGCGTGTGTATG
TGCAGCGGCCGATTTTCGACAGGTTCGTGCAGGCGCTCAAGGAGAAAGCCGAATCGCTGCGCATCGGGCCGTCCGACGCC
CCGGGCGTGGGCCTTGGCCCGCTGATCTCGGCGGAGCACAAGGCCAAGGTGATGTCCTACTACGACGTGGCGCGCAGCGA
GGGCGCGACAGTGGTGACCGGGGGCGGCGCACCGTCCATGCCGCCGGAGCTTGCCGAAGGCCATTGGGTGCAGCCGACGA
TCTGGACCGGCCTGCCCGAAAGCGCGCGCGTAATCCGGGAAGAAATCTTCGGCCCCTGCTGCCACATCGCACCGTTCGAC
ACCGAGGAGGAGGCCATCGCCCTGGCCAATGCCACGGACTATGGGCTGGCCACCACGGTCTGGACGCAGGACCTCGGCAC
GGCTCACCGCATGGCGCGCGCCATCGACGTCGGGCTGTGCTGGATCAATAGCTGGTTCCTGCGCGATCTCCGCACGGCAT
TCGGCGGGGCCAAGGCGTCGGGTATCGGTCGTGAGGGCGGCGTGCATTCCCTGGAGTTCTACACCGAACTGCGCAATGTG
ATGGTGAAGCTATGA

Upstream 100 bases:

>100_bases
CAGGACGAAGCTTGTGCACGCGCCGGCCTGCACGCCATCGGCCTGCAATGAAACTTTTTTCTCAACCAGGACAGGGACTG
TCTGCCTCGGGAATCCGACC

Downstream 100 bases:

>100_bases
GCGAAAGCGATTTTCAGGTACCCGAGACCCGCTACGTGAGAACAGGTGCGGTGACAACGCACATCCATGACGTTGGCCGG
GGTTCGCCCGTGCTGCTGCT

Product: betaine-aldehyde dehydrogenase

Products: 5-carboxymethyl-2-hydroxymuconate; NADH; H+

Alternate protein names: HMSD [H]

Number of amino acids: Translated: 484; Mature: 484

Protein sequence:

>484_residues
MKQFRNFINGEFVATNKTFENRAPVDNRVIGRVHEAGQAEVDAAVAAARAALHGDWGRMPVARRVELLHAVADEINRRFD
DFLEAELADTGKPRSLAAHIDIPRGAANFKVFADIVKNAPTESFEMTTPDGGTAISYALRAPLGVVAVVCPWNLPLLLMT
WKVGPALACGNTVIVKPSEETPATATLLGEVMEKVGVPKGVYNVLHGFGPGSAGEFLTRHPGVNGITFTGETRTGEAIMA
AAAKGVRPVSFELGGKNAGIVFADADFDKAVAGIARSAFENCGQVCLGTERVYVQRPIFDRFVQALKEKAESLRIGPSDA
PGVGLGPLISAEHKAKVMSYYDVARSEGATVVTGGGAPSMPPELAEGHWVQPTIWTGLPESARVIREEIFGPCCHIAPFD
TEEEAIALANATDYGLATTVWTQDLGTAHRMARAIDVGLCWINSWFLRDLRTAFGGAKASGIGREGGVHSLEFYTELRNV
MVKL

Sequences:

>Translated_484_residues
MKQFRNFINGEFVATNKTFENRAPVDNRVIGRVHEAGQAEVDAAVAAARAALHGDWGRMPVARRVELLHAVADEINRRFD
DFLEAELADTGKPRSLAAHIDIPRGAANFKVFADIVKNAPTESFEMTTPDGGTAISYALRAPLGVVAVVCPWNLPLLLMT
WKVGPALACGNTVIVKPSEETPATATLLGEVMEKVGVPKGVYNVLHGFGPGSAGEFLTRHPGVNGITFTGETRTGEAIMA
AAAKGVRPVSFELGGKNAGIVFADADFDKAVAGIARSAFENCGQVCLGTERVYVQRPIFDRFVQALKEKAESLRIGPSDA
PGVGLGPLISAEHKAKVMSYYDVARSEGATVVTGGGAPSMPPELAEGHWVQPTIWTGLPESARVIREEIFGPCCHIAPFD
TEEEAIALANATDYGLATTVWTQDLGTAHRMARAIDVGLCWINSWFLRDLRTAFGGAKASGIGREGGVHSLEFYTELRNV
MVKL
>Mature_484_residues
MKQFRNFINGEFVATNKTFENRAPVDNRVIGRVHEAGQAEVDAAVAAARAALHGDWGRMPVARRVELLHAVADEINRRFD
DFLEAELADTGKPRSLAAHIDIPRGAANFKVFADIVKNAPTESFEMTTPDGGTAISYALRAPLGVVAVVCPWNLPLLLMT
WKVGPALACGNTVIVKPSEETPATATLLGEVMEKVGVPKGVYNVLHGFGPGSAGEFLTRHPGVNGITFTGETRTGEAIMA
AAAKGVRPVSFELGGKNAGIVFADADFDKAVAGIARSAFENCGQVCLGTERVYVQRPIFDRFVQALKEKAESLRIGPSDA
PGVGLGPLISAEHKAKVMSYYDVARSEGATVVTGGGAPSMPPELAEGHWVQPTIWTGLPESARVIREEIFGPCCHIAPFD
TEEEAIALANATDYGLATTVWTQDLGTAHRMARAIDVGLCWINSWFLRDLRTAFGGAKASGIGREGGVHSLEFYTELRNV
MVKL

Specific function: 2-hydroxymuconic acid semialdehyde can be converted to 2-hydroxypent-2,4-dienoate either directly by the action of 2- hydroxymuconic semialdehyde hydrolase (HMSH) or by the action of three sequential enzymes, the first of which is HMSD [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aldehyde dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI12007648, Length=485, Percent_Identity=41.0309278350515, Blast_Score=387, Evalue=1e-107,
Organism=Homo sapiens, GI25952152, Length=482, Percent_Identity=37.9668049792531, Blast_Score=322, Evalue=3e-88,
Organism=Homo sapiens, GI115387104, Length=472, Percent_Identity=36.4406779661017, Blast_Score=313, Evalue=2e-85,
Organism=Homo sapiens, GI153266822, Length=486, Percent_Identity=36.4197530864198, Blast_Score=303, Evalue=2e-82,
Organism=Homo sapiens, GI25777732, Length=483, Percent_Identity=36.231884057971, Blast_Score=301, Evalue=8e-82,
Organism=Homo sapiens, GI25777724, Length=489, Percent_Identity=34.9693251533742, Blast_Score=299, Evalue=4e-81,
Organism=Homo sapiens, GI21361176, Length=486, Percent_Identity=35.59670781893, Blast_Score=296, Evalue=3e-80,
Organism=Homo sapiens, GI25777730, Length=483, Percent_Identity=35.4037267080745, Blast_Score=292, Evalue=5e-79,
Organism=Homo sapiens, GI25777728, Length=427, Percent_Identity=35.1288056206089, Blast_Score=274, Evalue=1e-73,
Organism=Homo sapiens, GI238814322, Length=486, Percent_Identity=33.5390946502058, Blast_Score=265, Evalue=7e-71,
Organism=Homo sapiens, GI301500698, Length=482, Percent_Identity=33.402489626556, Blast_Score=263, Evalue=3e-70,
Organism=Homo sapiens, GI21614513, Length=480, Percent_Identity=34.7916666666667, Blast_Score=256, Evalue=3e-68,
Organism=Homo sapiens, GI25777726, Length=489, Percent_Identity=31.4928425357873, Blast_Score=248, Evalue=7e-66,
Organism=Homo sapiens, GI4507229, Length=482, Percent_Identity=36.7219917012448, Blast_Score=241, Evalue=1e-63,
Organism=Homo sapiens, GI25777721, Length=495, Percent_Identity=35.959595959596, Blast_Score=233, Evalue=2e-61,
Organism=Homo sapiens, GI11095441, Length=481, Percent_Identity=30.7692307692308, Blast_Score=218, Evalue=1e-56,
Organism=Homo sapiens, GI310128093, Length=478, Percent_Identity=28.0334728033473, Blast_Score=168, Evalue=1e-41,
Organism=Homo sapiens, GI310128103, Length=478, Percent_Identity=28.0334728033473, Blast_Score=168, Evalue=1e-41,
Organism=Homo sapiens, GI188035924, Length=478, Percent_Identity=28.0334728033473, Blast_Score=168, Evalue=1e-41,
Organism=Homo sapiens, GI206597441, Length=447, Percent_Identity=28.6353467561521, Blast_Score=152, Evalue=7e-37,
Organism=Homo sapiens, GI206597439, Length=447, Percent_Identity=28.6353467561521, Blast_Score=152, Evalue=7e-37,
Organism=Homo sapiens, GI22907049, Length=447, Percent_Identity=28.6353467561521, Blast_Score=152, Evalue=7e-37,
Organism=Homo sapiens, GI4557303, Length=430, Percent_Identity=27.2093023255814, Blast_Score=150, Evalue=3e-36,
Organism=Homo sapiens, GI73466520, Length=430, Percent_Identity=27.2093023255814, Blast_Score=150, Evalue=3e-36,
Organism=Homo sapiens, GI310128091, Length=340, Percent_Identity=30, Blast_Score=149, Evalue=7e-36,
Organism=Homo sapiens, GI223972651, Length=333, Percent_Identity=30.9309309309309, Blast_Score=140, Evalue=2e-33,
Organism=Homo sapiens, GI71773324, Length=351, Percent_Identity=28.4900284900285, Blast_Score=133, Evalue=4e-31,
Organism=Homo sapiens, GI4502043, Length=351, Percent_Identity=28.4900284900285, Blast_Score=133, Evalue=4e-31,
Organism=Homo sapiens, GI238814371, Length=351, Percent_Identity=28.4900284900285, Blast_Score=133, Evalue=4e-31,
Organism=Homo sapiens, GI310128089, Length=327, Percent_Identity=29.3577981651376, Blast_Score=130, Evalue=3e-30,
Organism=Homo sapiens, GI73695881, Length=349, Percent_Identity=27.7936962750716, Blast_Score=129, Evalue=6e-30,
Organism=Homo sapiens, GI73695879, Length=349, Percent_Identity=27.7936962750716, Blast_Score=129, Evalue=6e-30,
Organism=Homo sapiens, GI310128097, Length=255, Percent_Identity=32.9411764705882, Blast_Score=127, Evalue=2e-29,
Organism=Homo sapiens, GI238859541, Length=462, Percent_Identity=26.4069264069264, Blast_Score=126, Evalue=5e-29,
Organism=Homo sapiens, GI25777736, Length=462, Percent_Identity=26.4069264069264, Blast_Score=125, Evalue=7e-29,
Organism=Homo sapiens, GI25777734, Length=462, Percent_Identity=26.4069264069264, Blast_Score=125, Evalue=7e-29,
Organism=Homo sapiens, GI310128095, Length=315, Percent_Identity=28.5714285714286, Blast_Score=117, Evalue=3e-26,
Organism=Homo sapiens, GI223972653, Length=333, Percent_Identity=27.6276276276276, Blast_Score=101, Evalue=1e-21,
Organism=Homo sapiens, GI310128087, Length=298, Percent_Identity=25.503355704698, Blast_Score=87, Evalue=4e-17,
Organism=Escherichia coli, GI1787558, Length=485, Percent_Identity=37.319587628866, Blast_Score=315, Evalue=6e-87,
Organism=Escherichia coli, GI1786504, Length=487, Percent_Identity=37.3716632443532, Blast_Score=308, Evalue=7e-85,
Organism=Escherichia coli, GI87082295, Length=488, Percent_Identity=36.4754098360656, Blast_Score=307, Evalue=1e-84,
Organism=Escherichia coli, GI87081896, Length=464, Percent_Identity=35.5603448275862, Blast_Score=289, Evalue=3e-79,
Organism=Escherichia coli, GI1787715, Length=488, Percent_Identity=36.2704918032787, Blast_Score=280, Evalue=2e-76,
Organism=Escherichia coli, GI1789015, Length=480, Percent_Identity=36.0416666666667, Blast_Score=278, Evalue=7e-76,
Organism=Escherichia coli, GI1787684, Length=484, Percent_Identity=32.8512396694215, Blast_Score=249, Evalue=2e-67,
Organism=Escherichia coli, GI87081926, Length=449, Percent_Identity=27.1714922048998, Blast_Score=165, Evalue=5e-42,
Organism=Escherichia coli, GI1788042, Length=487, Percent_Identity=30.1848049281314, Blast_Score=139, Evalue=3e-34,
Organism=Escherichia coli, GI1787250, Length=457, Percent_Identity=29.7592997811816, Blast_Score=139, Evalue=3e-34,
Organism=Escherichia coli, GI1787653, Length=384, Percent_Identity=25.2604166666667, Blast_Score=90, Evalue=3e-19,
Organism=Caenorhabditis elegans, GI17551164, Length=480, Percent_Identity=40.2083333333333, Blast_Score=335, Evalue=4e-92,
Organism=Caenorhabditis elegans, GI17562198, Length=486, Percent_Identity=38.0658436213992, Blast_Score=313, Evalue=2e-85,
Organism=Caenorhabditis elegans, GI25144435, Length=483, Percent_Identity=37.2670807453416, Blast_Score=312, Evalue=3e-85,
Organism=Caenorhabditis elegans, GI25143876, Length=480, Percent_Identity=35.8333333333333, Blast_Score=291, Evalue=4e-79,
Organism=Caenorhabditis elegans, GI25143874, Length=480, Percent_Identity=35.8333333333333, Blast_Score=291, Evalue=6e-79,
Organism=Caenorhabditis elegans, GI71995606, Length=483, Percent_Identity=37.888198757764, Blast_Score=288, Evalue=5e-78,
Organism=Caenorhabditis elegans, GI32564736, Length=427, Percent_Identity=37.0023419203747, Blast_Score=279, Evalue=3e-75,
Organism=Caenorhabditis elegans, GI133930964, Length=484, Percent_Identity=32.8512396694215, Blast_Score=256, Evalue=2e-68,
Organism=Caenorhabditis elegans, GI71995613, Length=421, Percent_Identity=38.9548693586698, Blast_Score=251, Evalue=4e-67,
Organism=Caenorhabditis elegans, GI17534119, Length=485, Percent_Identity=31.1340206185567, Blast_Score=211, Evalue=5e-55,
Organism=Caenorhabditis elegans, GI71986308, Length=484, Percent_Identity=31.8181818181818, Blast_Score=210, Evalue=1e-54,
Organism=Caenorhabditis elegans, GI115534176, Length=481, Percent_Identity=29.9376299376299, Blast_Score=177, Evalue=1e-44,
Organism=Caenorhabditis elegans, GI17534447, Length=481, Percent_Identity=27.4428274428274, Blast_Score=140, Evalue=2e-33,
Organism=Caenorhabditis elegans, GI32564151, Length=444, Percent_Identity=27.027027027027, Blast_Score=137, Evalue=9e-33,
Organism=Caenorhabditis elegans, GI115532534, Length=356, Percent_Identity=28.6516853932584, Blast_Score=129, Evalue=3e-30,
Organism=Caenorhabditis elegans, GI32566756, Length=344, Percent_Identity=26.7441860465116, Blast_Score=123, Evalue=3e-28,
Organism=Caenorhabditis elegans, GI25146391, Length=344, Percent_Identity=26.7441860465116, Blast_Score=123, Evalue=3e-28,
Organism=Caenorhabditis elegans, GI25146394, Length=344, Percent_Identity=26.7441860465116, Blast_Score=123, Evalue=3e-28,
Organism=Caenorhabditis elegans, GI17564084, Length=350, Percent_Identity=28.5714285714286, Blast_Score=122, Evalue=3e-28,
Organism=Caenorhabditis elegans, GI71990744, Length=315, Percent_Identity=27.3015873015873, Blast_Score=92, Evalue=4e-19,
Organism=Saccharomyces cerevisiae, GI6320917, Length=487, Percent_Identity=37.3716632443532, Blast_Score=325, Evalue=1e-89,
Organism=Saccharomyces cerevisiae, GI6324950, Length=489, Percent_Identity=35.7873210633947, Blast_Score=310, Evalue=3e-85,
Organism=Saccharomyces cerevisiae, GI6323821, Length=488, Percent_Identity=35.4508196721311, Blast_Score=296, Evalue=6e-81,
Organism=Saccharomyces cerevisiae, GI6323822, Length=488, Percent_Identity=35.4508196721311, Blast_Score=294, Evalue=3e-80,
Organism=Saccharomyces cerevisiae, GI6325196, Length=490, Percent_Identity=33.469387755102, Blast_Score=276, Evalue=5e-75,
Organism=Saccharomyces cerevisiae, GI6319478, Length=479, Percent_Identity=32.776617954071, Blast_Score=251, Evalue=1e-67,
Organism=Saccharomyces cerevisiae, GI6321828, Length=471, Percent_Identity=26.5392781316348, Blast_Score=156, Evalue=6e-39,
Organism=Saccharomyces cerevisiae, GI6321826, Length=510, Percent_Identity=25.0980392156863, Blast_Score=107, Evalue=4e-24,
Organism=Saccharomyces cerevisiae, GI6323757, Length=303, Percent_Identity=24.7524752475248, Blast_Score=80, Evalue=5e-16,
Organism=Drosophila melanogaster, GI20129399, Length=483, Percent_Identity=35.6107660455487, Blast_Score=309, Evalue=2e-84,
Organism=Drosophila melanogaster, GI24650465, Length=488, Percent_Identity=36.8852459016393, Blast_Score=294, Evalue=1e-79,
Organism=Drosophila melanogaster, GI281362580, Length=482, Percent_Identity=34.4398340248963, Blast_Score=285, Evalue=4e-77,
Organism=Drosophila melanogaster, GI62472918, Length=482, Percent_Identity=34.4398340248963, Blast_Score=285, Evalue=4e-77,
Organism=Drosophila melanogaster, GI62472926, Length=482, Percent_Identity=34.4398340248963, Blast_Score=285, Evalue=4e-77,
Organism=Drosophila melanogaster, GI62472936, Length=482, Percent_Identity=34.4398340248963, Blast_Score=285, Evalue=4e-77,
Organism=Drosophila melanogaster, GI21356737, Length=482, Percent_Identity=34.4398340248963, Blast_Score=285, Evalue=4e-77,
Organism=Drosophila melanogaster, GI24585660, Length=482, Percent_Identity=31.9502074688797, Blast_Score=253, Evalue=2e-67,
Organism=Drosophila melanogaster, GI24638878, Length=481, Percent_Identity=30.3534303534304, Blast_Score=194, Evalue=1e-49,
Organism=Drosophila melanogaster, GI24638876, Length=481, Percent_Identity=30.3534303534304, Blast_Score=194, Evalue=1e-49,
Organism=Drosophila melanogaster, GI24666674, Length=488, Percent_Identity=27.4590163934426, Blast_Score=154, Evalue=2e-37,
Organism=Drosophila melanogaster, GI281360301, Length=350, Percent_Identity=28.8571428571429, Blast_Score=132, Evalue=4e-31,
Organism=Drosophila melanogaster, GI281360303, Length=350, Percent_Identity=29.1428571428571, Blast_Score=132, Evalue=4e-31,
Organism=Drosophila melanogaster, GI45552499, Length=350, Percent_Identity=29.1428571428571, Blast_Score=132, Evalue=5e-31,
Organism=Drosophila melanogaster, GI281360299, Length=350, Percent_Identity=28.8571428571429, Blast_Score=132, Evalue=5e-31,
Organism=Drosophila melanogaster, GI281360297, Length=350, Percent_Identity=28.8571428571429, Blast_Score=132, Evalue=5e-31,
Organism=Drosophila melanogaster, GI281360295, Length=350, Percent_Identity=28.8571428571429, Blast_Score=132, Evalue=5e-31,
Organism=Drosophila melanogaster, GI24586250, Length=350, Percent_Identity=28.8571428571429, Blast_Score=132, Evalue=5e-31,
Organism=Drosophila melanogaster, GI24668425, Length=476, Percent_Identity=25.6302521008403, Blast_Score=123, Evalue=3e-28,
Organism=Drosophila melanogaster, GI24668417, Length=476, Percent_Identity=25.6302521008403, Blast_Score=123, Evalue=3e-28,
Organism=Drosophila melanogaster, GI24668413, Length=476, Percent_Identity=25.6302521008403, Blast_Score=123, Evalue=3e-28,
Organism=Drosophila melanogaster, GI281360293, Length=157, Percent_Identity=35.6687898089172, Blast_Score=95, Evalue=8e-20,
Organism=Drosophila melanogaster, GI28574525, Length=468, Percent_Identity=25.2136752136752, Blast_Score=94, Evalue=2e-19,
Organism=Drosophila melanogaster, GI28571798, Length=447, Percent_Identity=23.9373601789709, Blast_Score=89, Evalue=7e-18,
Organism=Drosophila melanogaster, GI28571796, Length=447, Percent_Identity=23.9373601789709, Blast_Score=89, Evalue=7e-18,
Organism=Drosophila melanogaster, GI28571794, Length=447, Percent_Identity=23.9373601789709, Blast_Score=89, Evalue=7e-18,
Organism=Drosophila melanogaster, GI28571806, Length=447, Percent_Identity=23.9373601789709, Blast_Score=89, Evalue=7e-18,
Organism=Drosophila melanogaster, GI28571802, Length=447, Percent_Identity=23.9373601789709, Blast_Score=89, Evalue=8e-18,
Organism=Drosophila melanogaster, GI28571800, Length=447, Percent_Identity=23.9373601789709, Blast_Score=89, Evalue=8e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016161
- InterPro:   IPR016163
- InterPro:   IPR016160
- InterPro:   IPR016162
- InterPro:   IPR015590
- InterPro:   IPR017628 [H]

Pfam domain/function: PF00171 Aldedh [H]

EC number: 1.2.1.60

Molecular weight: Translated: 51764; Mature: 51764

Theoretical pI: Translated: 6.15; Mature: 6.15

Prosite motif: PS00687 ALDEHYDE_DEHYDR_GLU ; PS00070 ALDEHYDE_DEHYDR_CYS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKQFRNFINGEFVATNKTFENRAPVDNRVIGRVHEAGQAEVDAAVAAARAALHGDWGRMP
CCHHHHHHCCCEEEECCCCCCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCCC
VARRVELLHAVADEINRRFDDFLEAELADTGKPRSLAAHIDIPRGAANFKVFADIVKNAP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCCCHHHHHHHHHCCC
TESFEMTTPDGGTAISYALRAPLGVVAVVCPWNLPLLLMTWKVGPALACGNTVIVKPSEE
CCCEEEECCCCCCHHHHHHHCCCCEEEEEECCCCCEEEEEECCCCCEECCCEEEEECCCC
TPATATLLGEVMEKVGVPKGVYNVLHGFGPGSAGEFLTRHPGVNGITFTGETRTGEAIMA
CCHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCCCHHHCCCCCCCEEEECCCCCCHHHHH
AAAKGVRPVSFELGGKNAGIVFADADFDKAVAGIARSAFENCGQVCLGTERVYVQRPIFD
HHHCCCCEEEEEECCCCCCEEEECCCHHHHHHHHHHHHHHHCCCEEECCCEEEEECCHHH
RFVQALKEKAESLRIGPSDAPGVGLGPLISAEHKAKVMSYYDVARSEGATVVTGGGAPSM
HHHHHHHHHHHHEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCEEEECCCCCCC
PPELAEGHWVQPTIWTGLPESARVIREEIFGPCCHIAPFDTEEEAIALANATDYGLATTV
CHHHCCCCCCCCHHCCCCCHHHHHHHHHHCCCEECCCCCCCCCCEEEEECCCCCCCEEEH
WTQDLGTAHRMARAIDVGLCWINSWFLRDLRTAFGGAKASGIGREGGVHSLEFYTELRNV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHH
MVKL
HHCC
>Mature Secondary Structure
MKQFRNFINGEFVATNKTFENRAPVDNRVIGRVHEAGQAEVDAAVAAARAALHGDWGRMP
CCHHHHHHCCCEEEECCCCCCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCCC
VARRVELLHAVADEINRRFDDFLEAELADTGKPRSLAAHIDIPRGAANFKVFADIVKNAP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCCCHHHHHHHHHCCC
TESFEMTTPDGGTAISYALRAPLGVVAVVCPWNLPLLLMTWKVGPALACGNTVIVKPSEE
CCCEEEECCCCCCHHHHHHHCCCCEEEEEECCCCCEEEEEECCCCCEECCCEEEEECCCC
TPATATLLGEVMEKVGVPKGVYNVLHGFGPGSAGEFLTRHPGVNGITFTGETRTGEAIMA
CCHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCCCHHHCCCCCCCEEEECCCCCCHHHHH
AAAKGVRPVSFELGGKNAGIVFADADFDKAVAGIARSAFENCGQVCLGTERVYVQRPIFD
HHHCCCCEEEEEECCCCCCEEEECCCHHHHHHHHHHHHHHHCCCEEECCCEEEEECCHHH
RFVQALKEKAESLRIGPSDAPGVGLGPLISAEHKAKVMSYYDVARSEGATVVTGGGAPSM
HHHHHHHHHHHHEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCEEEECCCCCCC
PPELAEGHWVQPTIWTGLPESARVIREEIFGPCCHIAPFDTEEEAIALANATDYGLATTV
CHHHCCCCCCCCHHCCCCCHHHHHHHHHHCCCEECCCCCCCCCCEEEEECCCCCCCEEEH
WTQDLGTAHRMARAIDVGLCWINSWFLRDLRTAFGGAKASGIGREGGVHSLEFYTELRNV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHH
MVKL
HHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: 5-carboxymethyl-2-hydroxymuconate semialdehyde; H2O; NAD+

Specific reaction: 5-carboxymethyl-2-hydroxymuconate semialdehyde + H2O + NAD+ = 5-carboxymethyl-2-hydroxymuconate + NADH + H+

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2194577 [H]