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The map label for this gene is yafC [C]

Identifier: 73539470

GI number: 73539470

Start: 2472809

End: 2473723

Strand: Direct

Name: yafC [C]

Synonym: Reut_B5648

Alternate gene names: 73539470

Gene position: 2472809-2473723 (Clockwise)

Preceding gene: 73539464

Following gene: 73539475

Centisome position: 90.71

GC content: 63.93

Gene sequence:

>915_bases
ATGGACAAACTGCTTGCACTGAAGATGTTCGTGGAGACCGTGGACGCAAAGGGATTCTCGGCCGCTGCGCGAAGGCTGGA
CCTGGCGACGTCGTCCGTGACGCGTGCGCTTGATGGACTGGAGGCGTCGCTCGGCGCCGTGCTGCTGAACCGCTCGACGC
GGCAGATCACGGTGACGGAGGCCGGCGCCACCTACTATCAGCGGGCTCGAAGGATCCTGGATGCCGTGGAAGAGGCTGAT
GCGCTGATCGCGGATCGAGGCGAGGAGCCGGTCGGGCAGTTGCGCGTGTCATTGCCGGTGGCCTTCGGGCGGCGGTGCAT
CGCGCCGTATCTCGGCGGCTGGCTGGCGAAGTATCCACAGCTCGAGGTCGACGTGACGCTGACCGACGATATCGTCGACC
TCGTGGGCGAGCGCGTCGATCTGTCCGTGCGGCTCGGCAGCCCTGCGTCGTATGACAATGTCGTCGCGCGTGAGATCGGG
CGCTTTCGTCGCCGGGTGGTCGCCAGTCCGGCCTATCTGGAAAGCCGGGGCTGTCCCGATGATCCCGTTGATCTGGTCAA
CCATCGTTGCCTTCGGTTCAGCTACGGCACGCGCGACCAGGTCTGGACATTTCGCCAGGGCGACAGCGAGACCAAAGTTC
CCGTCAGCGGACATTTTCGCAGCAACAACATCGACGTCTTGCGCGATATCGCGCTCGCGGGCGCCGGAATCGGCCTTCTG
CCGGACTGGCTGATCGATGAAGATATCGAAAGCCAACGACTGATGCCATTGTTCGATGCATGGTCAGTCAACCCGGATCA
GGCCAGTTCCGCAATCTCCGCCCTGTATCTGCCGAACCAGCGCGGTTCGCGCAGAATCGCGGCGTTCATGGATTTCCTCG
CAGCGCTGCCAGGGCCGACCCGGCGTCGGGACTGA

Upstream 100 bases:

>100_bases
AAGCGACCGCGTCGCGATCTTTGACGCGAATCTCTCGGCATAATCTGTCCGTGCCTTGGGTACGGACAAGCCAATTCAAT
CAACAAGGATCACGGCAAGG

Downstream 100 bases:

>100_bases
TCGCTCGCCCGTGCCGCGGCGGCGTGGTCTCAGCGCCGCGAAGCGATCGCCAGCGCCACCAGCGAGACCGTCGCAAGACC
GCTGCCTGCCGCGACCACGC

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: ORF2 [H]

Number of amino acids: Translated: 304; Mature: 304

Protein sequence:

>304_residues
MDKLLALKMFVETVDAKGFSAAARRLDLATSSVTRALDGLEASLGAVLLNRSTRQITVTEAGATYYQRARRILDAVEEAD
ALIADRGEEPVGQLRVSLPVAFGRRCIAPYLGGWLAKYPQLEVDVTLTDDIVDLVGERVDLSVRLGSPASYDNVVAREIG
RFRRRVVASPAYLESRGCPDDPVDLVNHRCLRFSYGTRDQVWTFRQGDSETKVPVSGHFRSNNIDVLRDIALAGAGIGLL
PDWLIDEDIESQRLMPLFDAWSVNPDQASSAISALYLPNQRGSRRIAAFMDFLAALPGPTRRRD

Sequences:

>Translated_304_residues
MDKLLALKMFVETVDAKGFSAAARRLDLATSSVTRALDGLEASLGAVLLNRSTRQITVTEAGATYYQRARRILDAVEEAD
ALIADRGEEPVGQLRVSLPVAFGRRCIAPYLGGWLAKYPQLEVDVTLTDDIVDLVGERVDLSVRLGSPASYDNVVAREIG
RFRRRVVASPAYLESRGCPDDPVDLVNHRCLRFSYGTRDQVWTFRQGDSETKVPVSGHFRSNNIDVLRDIALAGAGIGLL
PDWLIDEDIESQRLMPLFDAWSVNPDQASSAISALYLPNQRGSRRIAAFMDFLAALPGPTRRRD
>Mature_304_residues
MDKLLALKMFVETVDAKGFSAAARRLDLATSSVTRALDGLEASLGAVLLNRSTRQITVTEAGATYYQRARRILDAVEEAD
ALIADRGEEPVGQLRVSLPVAFGRRCIAPYLGGWLAKYPQLEVDVTLTDDIVDLVGERVDLSVRLGSPASYDNVVAREIG
RFRRRVVASPAYLESRGCPDDPVDLVNHRCLRFSYGTRDQVWTFRQGDSETKVPVSGHFRSNNIDVLRDIALAGAGIGLL
PDWLIDEDIESQRLMPLFDAWSVNPDQASSAISALYLPNQRGSRRIAAFMDFLAALPGPTRRRD

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1786401, Length=288, Percent_Identity=32.2916666666667, Blast_Score=151, Evalue=7e-38,
Organism=Escherichia coli, GI145693193, Length=298, Percent_Identity=29.5302013422819, Blast_Score=139, Evalue=2e-34,
Organism=Escherichia coli, GI1789440, Length=293, Percent_Identity=32.4232081911263, Blast_Score=136, Evalue=2e-33,
Organism=Escherichia coli, GI87081978, Length=291, Percent_Identity=32.3024054982818, Blast_Score=133, Evalue=1e-32,
Organism=Escherichia coli, GI1789639, Length=248, Percent_Identity=31.0483870967742, Blast_Score=127, Evalue=1e-30,
Organism=Escherichia coli, GI1787128, Length=287, Percent_Identity=29.9651567944251, Blast_Score=123, Evalue=1e-29,
Organism=Escherichia coli, GI1787589, Length=278, Percent_Identity=27.6978417266187, Blast_Score=117, Evalue=9e-28,
Organism=Escherichia coli, GI1789173, Length=295, Percent_Identity=25.7627118644068, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1787601, Length=155, Percent_Identity=23.2258064516129, Blast_Score=66, Evalue=3e-12,
Organism=Escherichia coli, GI1790011, Length=270, Percent_Identity=24.0740740740741, Blast_Score=64, Evalue=1e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 33534; Mature: 33534

Theoretical pI: Translated: 5.51; Mature: 5.51

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDKLLALKMFVETVDAKGFSAAARRLDLATSSVTRALDGLEASLGAVLLNRSTRQITVTE
CCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEE
AGATYYQRARRILDAVEEADALIADRGEEPVGQLRVSLPVAFGRRCIAPYLGGWLAKYPQ
CCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHEEEECCHHHHHHHHHHHHHHHHHHCCC
LEVDVTLTDDIVDLVGERVDLSVRLGSPASYDNVVAREIGRFRRRVVASPAYLESRGCPD
EEEEEEECHHHHHHCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHCCCHHHHCCCCCC
DPVDLVNHRCLRFSYGTRDQVWTFRQGDSETKVPVSGHFRSNNIDVLRDIALAGAGIGLL
CHHHHHCCCEEEEECCCCCCEEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCC
PDWLIDEDIESQRLMPLFDAWSVNPDQASSAISALYLPNQRGSRRIAAFMDFLAALPGPT
CHHHCCCCCCCCCCCCHHHCCCCCHHHHHHHHHEEECCCCCCCHHHHHHHHHHHHCCCCC
RRRD
CCCC
>Mature Secondary Structure
MDKLLALKMFVETVDAKGFSAAARRLDLATSSVTRALDGLEASLGAVLLNRSTRQITVTE
CCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEE
AGATYYQRARRILDAVEEADALIADRGEEPVGQLRVSLPVAFGRRCIAPYLGGWLAKYPQ
CCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHEEEECCHHHHHHHHHHHHHHHHHHCCC
LEVDVTLTDDIVDLVGERVDLSVRLGSPASYDNVVAREIGRFRRRVVASPAYLESRGCPD
EEEEEEECHHHHHHCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHCCCHHHHCCCCCC
DPVDLVNHRCLRFSYGTRDQVWTFRQGDSETKVPVSGHFRSNNIDVLRDIALAGAGIGLL
CHHHHHCCCEEEEECCCCCCEEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCC
PDWLIDEDIESQRLMPLFDAWSVNPDQASSAISALYLPNQRGSRRIAAFMDFLAALPGPT
CHHHCCCCCCCCCCCCHHHCCCCCHHHHHHHHHEEECCCCCCCHHHHHHHHHHHHCCCCC
RRRD
CCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8635745; 7542800 [H]