BacMap

Definition	Ralstonia eutropha JMP134 chromosome chromosome 2, complete sequence.
Accession	NC_007348
Length	2,726,152

Click here to switch to the map view.

The map label for this gene is fabG [H]

Identifier: 73539410

GI number: 73539410

Start: 2406245

End: 2406976

Strand: Direct

Name: fabG [H]

Synonym: Reut_B5588

Alternate gene names: 73539410

Gene position: 2406245-2406976 (Clockwise)

Preceding gene: 73539409

Following gene: 73539411

Centisome position: 88.27

GC content: 68.31

Gene sequence:

>732_bases
ATGTCTCTTCCCAACGCCACGATCGTCACCGGCGCCAGTTCCGGTATCGGGCGCGCCATCAGCGAAATGCTGCTGGCAGA
CGGCAATACCCGGGTGGTCAATATCGACTACACCGAGCCGGGCTGGTCGCACCCTAACATGACCTTTTTCCAGGCTGACC
TGACCAATGCCGAGGCGACACGCGCCGTGGCGGAGCAGGTCACCTCGCAGTTCGACGTCACGCGGCTCGTGAACAACGCG
GGCGCCACGCGTCCGGGCACGGCCGATTCGGCCACCGTGGCCGACCTCGACTATGTCGTCGGCCTGCACTTGCAGGCGGC
CATGCTGCTCACGCAGGCATGCCTGCCTGCGATGCGCGCCGCCGGGTTCGGCCGCGTGGTCAACATGGCTTCGCGCGCGG
CGCTGGGCAAGCCCGAGCGCGTGGTGTACTCGGCGACCAAGGCCGGGCTGATCGGCATGACCCGTACGCTGGCCATGGAG
CTCGGCGGCGACGGCATCACCGTGAACGCGGTGGCGCCGGGCCCGATCGCCACGGAGCTGTTCCGCAAGAGCAATCCCGA
AGGCAGCGAGCAGACCCGCCGCATCCTCGCGAGCATCGCCGTGAAGCGCATGGGCACGCCGGAAGACGTGGCACGCGCCG
CGCTGTTCTTCCTGTCGCCCGACAACGGGTTCGTCACGGGGCAAGTGCTCTACGTGTGCGGCGGCACCACGCTTGGCGTG
GCACCGGTCTGA

Upstream 100 bases:

>100_bases
GCTGCAGGGCCGACAGGCTCGCCGGTCCGGCGGCATGTAGTGAGTGAAGTCGCGATTGTTTGCAAGATCCGGTCCACGAG
CGGCCGGAGCGGAGTTGAAG

Downstream 100 bases:

>100_bases
GGCGCACGCCTGCTCAAGCATTCAAATAGAACAGACGTTATTAAAACGTCATATCAGGATGTGATCCTTTTCCCATGGGC
CACATCCGGCGAGGACAGCG

Product: NAD-dependent epimerase/dehydratase

Products: NA

Alternate protein names: 3-ketoacyl-acyl carrier protein reductase [H]

Number of amino acids: Translated: 243; Mature: 242

Protein sequence:

>243_residues
MSLPNATIVTGASSGIGRAISEMLLADGNTRVVNIDYTEPGWSHPNMTFFQADLTNAEATRAVAEQVTSQFDVTRLVNNA
GATRPGTADSATVADLDYVVGLHLQAAMLLTQACLPAMRAAGFGRVVNMASRAALGKPERVVYSATKAGLIGMTRTLAME
LGGDGITVNAVAPGPIATELFRKSNPEGSEQTRRILASIAVKRMGTPEDVARAALFFLSPDNGFVTGQVLYVCGGTTLGV
APV

Sequences:

>Translated_243_residues
MSLPNATIVTGASSGIGRAISEMLLADGNTRVVNIDYTEPGWSHPNMTFFQADLTNAEATRAVAEQVTSQFDVTRLVNNA
GATRPGTADSATVADLDYVVGLHLQAAMLLTQACLPAMRAAGFGRVVNMASRAALGKPERVVYSATKAGLIGMTRTLAME
LGGDGITVNAVAPGPIATELFRKSNPEGSEQTRRILASIAVKRMGTPEDVARAALFFLSPDNGFVTGQVLYVCGGTTLGV
APV
>Mature_242_residues
SLPNATIVTGASSGIGRAISEMLLADGNTRVVNIDYTEPGWSHPNMTFFQADLTNAEATRAVAEQVTSQFDVTRLVNNAG
ATRPGTADSATVADLDYVVGLHLQAAMLLTQACLPAMRAAGFGRVVNMASRAALGKPERVVYSATKAGLIGMTRTLAMEL
GGDGITVNAVAPGPIATELFRKSNPEGSEQTRRILASIAVKRMGTPEDVARAALFFLSPDNGFVTGQVLYVCGGTTLGVA
PV

Specific function: Fatty acid biosynthesis pathway; first reduction step. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI15277342, Length=247, Percent_Identity=35.2226720647773, Blast_Score=115, Evalue=5e-26,
Organism=Homo sapiens, GI32483357, Length=248, Percent_Identity=33.0645161290323, Blast_Score=92, Evalue=4e-19,
Organism=Homo sapiens, GI19923817, Length=252, Percent_Identity=28.968253968254, Blast_Score=90, Evalue=2e-18,
Organism=Homo sapiens, GI66933014, Length=203, Percent_Identity=30.5418719211823, Blast_Score=89, Evalue=5e-18,
Organism=Homo sapiens, GI40254992, Length=238, Percent_Identity=31.0924369747899, Blast_Score=86, Evalue=4e-17,
Organism=Homo sapiens, GI59889578, Length=220, Percent_Identity=31.8181818181818, Blast_Score=83, Evalue=2e-16,
Organism=Homo sapiens, GI126723750, Length=252, Percent_Identity=30.1587301587302, Blast_Score=75, Evalue=5e-14,
Organism=Homo sapiens, GI5031737, Length=241, Percent_Identity=29.8755186721992, Blast_Score=72, Evalue=6e-13,
Organism=Homo sapiens, GI7705925, Length=237, Percent_Identity=31.2236286919831, Blast_Score=70, Evalue=1e-12,
Organism=Escherichia coli, GI1787335, Length=236, Percent_Identity=33.8983050847458, Blast_Score=116, Evalue=2e-27,
Organism=Escherichia coli, GI87082100, Length=249, Percent_Identity=30.9236947791165, Blast_Score=103, Evalue=1e-23,
Organism=Escherichia coli, GI87082160, Length=240, Percent_Identity=32.5, Blast_Score=96, Evalue=3e-21,
Organism=Escherichia coli, GI1789208, Length=238, Percent_Identity=29.8319327731092, Blast_Score=92, Evalue=3e-20,
Organism=Escherichia coli, GI1787905, Length=239, Percent_Identity=32.2175732217573, Blast_Score=89, Evalue=3e-19,
Organism=Escherichia coli, GI2367175, Length=245, Percent_Identity=30.2040816326531, Blast_Score=79, Evalue=3e-16,
Organism=Escherichia coli, GI1789378, Length=248, Percent_Identity=27.8225806451613, Blast_Score=79, Evalue=3e-16,
Organism=Escherichia coli, GI1790717, Length=243, Percent_Identity=27.1604938271605, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI2367365, Length=232, Percent_Identity=28.448275862069, Blast_Score=75, Evalue=4e-15,
Organism=Escherichia coli, GI1786812, Length=242, Percent_Identity=27.2727272727273, Blast_Score=70, Evalue=8e-14,
Organism=Escherichia coli, GI1788459, Length=243, Percent_Identity=28.8065843621399, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1789057, Length=219, Percent_Identity=26.027397260274, Blast_Score=64, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17561402, Length=243, Percent_Identity=29.2181069958848, Blast_Score=94, Evalue=4e-20,
Organism=Caenorhabditis elegans, GI25147288, Length=245, Percent_Identity=31.8367346938775, Blast_Score=94, Evalue=5e-20,
Organism=Caenorhabditis elegans, GI17560676, Length=243, Percent_Identity=30.0411522633745, Blast_Score=87, Evalue=7e-18,
Organism=Caenorhabditis elegans, GI17562910, Length=260, Percent_Identity=30, Blast_Score=87, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI17555706, Length=241, Percent_Identity=31.5352697095436, Blast_Score=86, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI71994604, Length=248, Percent_Identity=30.241935483871, Blast_Score=86, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI71994600, Length=249, Percent_Identity=29.718875502008, Blast_Score=86, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI17538480, Length=261, Percent_Identity=30.2681992337165, Blast_Score=86, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI17559104, Length=259, Percent_Identity=28.1853281853282, Blast_Score=80, Evalue=8e-16,
Organism=Caenorhabditis elegans, GI115534694, Length=248, Percent_Identity=29.0322580645161, Blast_Score=79, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17562904, Length=256, Percent_Identity=28.90625, Blast_Score=78, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI17551412, Length=257, Percent_Identity=28.0155642023346, Blast_Score=75, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI17538486, Length=257, Percent_Identity=26.4591439688716, Blast_Score=74, Evalue=7e-14,
Organism=Caenorhabditis elegans, GI17560332, Length=259, Percent_Identity=28.1853281853282, Blast_Score=74, Evalue=9e-14,
Organism=Caenorhabditis elegans, GI17563726, Length=260, Percent_Identity=28.0769230769231, Blast_Score=70, Evalue=8e-13,
Organism=Caenorhabditis elegans, GI17560150, Length=260, Percent_Identity=28.4615384615385, Blast_Score=67, Evalue=9e-12,
Organism=Caenorhabditis elegans, GI17562990, Length=257, Percent_Identity=27.6264591439689, Blast_Score=66, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17562906, Length=258, Percent_Identity=27.1317829457364, Blast_Score=64, Evalue=8e-11,
Organism=Saccharomyces cerevisiae, GI6322861, Length=248, Percent_Identity=29.8387096774194, Blast_Score=76, Evalue=5e-15,
Organism=Saccharomyces cerevisiae, GI6324126, Length=186, Percent_Identity=29.5698924731183, Blast_Score=69, Evalue=9e-13,
Organism=Saccharomyces cerevisiae, GI6323882, Length=192, Percent_Identity=30.2083333333333, Blast_Score=64, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24639444, Length=240, Percent_Identity=31.6666666666667, Blast_Score=97, Evalue=1e-20,
Organism=Drosophila melanogaster, GI23397609, Length=248, Percent_Identity=32.6612903225806, Blast_Score=96, Evalue=1e-20,
Organism=Drosophila melanogaster, GI21355319, Length=242, Percent_Identity=30.1652892561983, Blast_Score=92, Evalue=4e-19,
Organism=Drosophila melanogaster, GI24643142, Length=237, Percent_Identity=29.535864978903, Blast_Score=79, Evalue=3e-15,
Organism=Drosophila melanogaster, GI24644339, Length=244, Percent_Identity=28.6885245901639, Blast_Score=77, Evalue=1e-14,
Organism=Drosophila melanogaster, GI28571526, Length=244, Percent_Identity=29.5081967213115, Blast_Score=73, Evalue=2e-13,
Organism=Drosophila melanogaster, GI21357041, Length=249, Percent_Identity=29.3172690763052, Blast_Score=72, Evalue=5e-13,
Organism=Drosophila melanogaster, GI221331216, Length=241, Percent_Identity=31.1203319502075, Blast_Score=71, Evalue=6e-13,
Organism=Drosophila melanogaster, GI24665247, Length=241, Percent_Identity=31.1203319502075, Blast_Score=71, Evalue=6e-13,
Organism=Drosophila melanogaster, GI24644337, Length=195, Percent_Identity=32.8205128205128, Blast_Score=70, Evalue=1e-12,
Organism=Drosophila melanogaster, GI18859837, Length=186, Percent_Identity=30.1075268817204, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI221331218, Length=240, Percent_Identity=30, Blast_Score=66, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24665243, Length=240, Percent_Identity=30, Blast_Score=65, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011284
- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: =1.1.1.100 [H]

Molecular weight: Translated: 25300; Mature: 25169

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: PS00061 ADH_SHORT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLPNATIVTGASSGIGRAISEMLLADGNTRVVNIDYTEPGWSHPNMTFFQADLTNAEAT
CCCCCCEEEECCCCCHHHHHHHHHHCCCCEEEEEEECCCCCCCCCCCEEEEECCCCHHHH
RAVAEQVTSQFDVTRLVNNAGATRPGTADSATVADLDYVVGLHLQAAMLLTQACLPAMRA
HHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AGFGRVVNMASRAALGKPERVVYSATKAGLIGMTRTLAMELGGDGITVNAVAPGPIATEL
CCHHHHHHHHHHHHCCCCCCEEEEHHHCCHHHHHHHHHHEECCCCEEEEEECCCHHHHHH
FRKSNPEGSEQTRRILASIAVKRMGTPEDVARAALFFLSPDNGFVTGQVLYVCGGTTLGV
HHCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHEEEEEECCCCCEEEEEEEEEECCCEECC
APV
CCC
>Mature Secondary Structure 
SLPNATIVTGASSGIGRAISEMLLADGNTRVVNIDYTEPGWSHPNMTFFQADLTNAEAT
CCCCCEEEECCCCCHHHHHHHHHHCCCCEEEEEEECCCCCCCCCCCEEEEECCCCHHHH
RAVAEQVTSQFDVTRLVNNAGATRPGTADSATVADLDYVVGLHLQAAMLLTQACLPAMRA
HHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AGFGRVVNMASRAALGKPERVVYSATKAGLIGMTRTLAMELGGDGITVNAVAPGPIATEL
CCHHHHHHHHHHHHCCCCCCEEEEHHHCCHHHHHHHHHHEECCCCEEEEEECCCHHHHHH
FRKSNPEGSEQTRRILASIAVKRMGTPEDVARAALFFLSPDNGFVTGQVLYVCGGTTLGV
HHCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHEEEEEECCCCCEEEEEEEEEECCCEECC
APV
CCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10360571 [H]