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The map label for this gene is pcaI [H]

Identifier: 73539407

GI number: 73539407

Start: 2403439

End: 2404179

Strand: Direct

Name: pcaI [H]

Synonym: Reut_B5585

Alternate gene names: 73539407

Gene position: 2403439-2404179 (Clockwise)

Preceding gene: 73539405

Following gene: 73539408

Centisome position: 88.16

GC content: 64.78

Gene sequence:

>741_bases
ATGCCCGGAGACAGTTTTTGCGCGCCGCGCCTTGCGGCCGGTTCCGGCACCTGCCAGACCTCTACCCGGACTGGAACGCA
AGTGATCAACAAGCTATTCGACTCGGTGGAAGCGGCGGTGGCCGGCATCCACGACGGCGCCACGATCCTGATCGGCGGTT
TCGGCATGGCAGGCATGCCCGCTGAACTGATCGATGCCCTGATCGCCCAAGGCGCGCGCGACCTCACCATCGTCAACAAC
AACGCCGGCAACGGCGACACCGGCCTGGCCGCGCTGCTGAAGACCAAACGCGTGCGCAAGATCATCTGTTCGTTCCCGCG
CCAGACGGACTCGTACGTGTTCGACTCGCTGTACCACGCTGGCGAAATCGAACTGGAACTGGTGCCGCAGGGCAACCTGG
CCGAGCGCATCCGCGCCGCCGGTGCCGGCATCGGCGGTTTCTTCACGCGCACGGCCTACGGCACGCCGCTGGCCGAAGGC
AAGGAAACGCGCATCATCGACGGCCAGGGCTATGTTTTCGAAAAGCCCATTCACGCCGACTTCGCCCTGATCAAGGCCGA
CAAGGCCGACCGCTGGGGCAACCTGACGTATCGCAAGACCGCTCGCAACTTCGGCCCGATCATGGCCATGGCTGCCAAGT
GCCCCATCGTGCAGGTGAGCCACGTGGTGGAACTGGGCGAGCTGGATCCCGAGCACATCGTGACGCCGGGCCTGTTCGTC
AAGCGCGTGGTGAAGGTCTGA

Upstream 100 bases:

>100_bases
TCAAGTTCGTAATTAGAACAAAACTGACGCACTTCTGTTGGAACACGTCTTGGCTAGTGCGCCATCACCGGTGCTTGCGC
CAGACGCCCGTCCGGCAGGC

Downstream 100 bases:

>100_bases
GCGAAGGAGAGCGAACATGCAAAAACTGACCCGCGACCAAATGGCCGCCCGCGTGGCCAAAGACATCCCCGAAGGTGCCG
TGGTGAACCTCGGCATCGGA

Product: coenzyme A transferase

Products: NA

Alternate protein names: Beta-ketoadipate:succinyl-CoA transferase subunit A [H]

Number of amino acids: Translated: 246; Mature: 245

Protein sequence:

>246_residues
MPGDSFCAPRLAAGSGTCQTSTRTGTQVINKLFDSVEAAVAGIHDGATILIGGFGMAGMPAELIDALIAQGARDLTIVNN
NAGNGDTGLAALLKTKRVRKIICSFPRQTDSYVFDSLYHAGEIELELVPQGNLAERIRAAGAGIGGFFTRTAYGTPLAEG
KETRIIDGQGYVFEKPIHADFALIKADKADRWGNLTYRKTARNFGPIMAMAAKCPIVQVSHVVELGELDPEHIVTPGLFV
KRVVKV

Sequences:

>Translated_246_residues
MPGDSFCAPRLAAGSGTCQTSTRTGTQVINKLFDSVEAAVAGIHDGATILIGGFGMAGMPAELIDALIAQGARDLTIVNN
NAGNGDTGLAALLKTKRVRKIICSFPRQTDSYVFDSLYHAGEIELELVPQGNLAERIRAAGAGIGGFFTRTAYGTPLAEG
KETRIIDGQGYVFEKPIHADFALIKADKADRWGNLTYRKTARNFGPIMAMAAKCPIVQVSHVVELGELDPEHIVTPGLFV
KRVVKV
>Mature_245_residues
PGDSFCAPRLAAGSGTCQTSTRTGTQVINKLFDSVEAAVAGIHDGATILIGGFGMAGMPAELIDALIAQGARDLTIVNNN
AGNGDTGLAALLKTKRVRKIICSFPRQTDSYVFDSLYHAGEIELELVPQGNLAERIRAAGAGIGGFFTRTAYGTPLAEGK
ETRIIDGQGYVFEKPIHADFALIKADKADRWGNLTYRKTARNFGPIMAMAAKCPIVQVSHVVELGELDPEHIVTPGLFVK
RVVKV

Specific function: SHORT-CHAIN FATTY ACIDS METABOLISM. [C]

COG id: COG1788

COG function: function code I; Acyl CoA:acetate/3-ketoacid CoA transferase, alpha subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 3-oxoacid CoA-transferase subunit A family [H]

Homologues:

Organism=Homo sapiens, GI4557817, Length=266, Percent_Identity=41.3533834586466, Blast_Score=195, Evalue=4e-50,
Organism=Homo sapiens, GI11545841, Length=257, Percent_Identity=41.6342412451362, Blast_Score=177, Evalue=8e-45,
Organism=Escherichia coli, GI1788551, Length=214, Percent_Identity=42.9906542056075, Blast_Score=184, Evalue=5e-48,
Organism=Caenorhabditis elegans, GI17531517, Length=234, Percent_Identity=43.5897435897436, Blast_Score=186, Evalue=9e-48,
Organism=Drosophila melanogaster, GI21358325, Length=261, Percent_Identity=39.8467432950192, Blast_Score=187, Evalue=8e-48,
Organism=Drosophila melanogaster, GI24655794, Length=242, Percent_Identity=41.7355371900826, Blast_Score=186, Evalue=1e-47,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012792
- InterPro:   IPR004165
- InterPro:   IPR004163 [H]

Pfam domain/function: PF01144 CoA_trans [H]

EC number: =2.8.3.6 [H]

Molecular weight: Translated: 26172; Mature: 26041

Theoretical pI: Translated: 7.98; Mature: 7.98

Prosite motif: PS01273 COA_TRANSF_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPGDSFCAPRLAAGSGTCQTSTRTGTQVINKLFDSVEAAVAGIHDGATILIGGFGMAGMP
CCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCC
AELIDALIAQGARDLTIVNNNAGNGDTGLAALLKTKRVRKIICSFPRQTDSYVFDSLYHA
HHHHHHHHHCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCC
GEIELELVPQGNLAERIRAAGAGIGGFFTRTAYGTPLAEGKETRIIDGQGYVFEKPIHAD
CCEEEEEECCCCHHHHHHHHCCCCCHHHHHHCCCCCCCCCCCEEEECCCCCEEECCCCCC
FALIKADKADRWGNLTYRKTARNFGPIMAMAAKCPIVQVSHVVELGELDPEHIVTPGLFV
EEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCHHHHCCCHHHH
KRVVKV
HHHHCC
>Mature Secondary Structure 
PGDSFCAPRLAAGSGTCQTSTRTGTQVINKLFDSVEAAVAGIHDGATILIGGFGMAGMP
CCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCC
AELIDALIAQGARDLTIVNNNAGNGDTGLAALLKTKRVRKIICSFPRQTDSYVFDSLYHA
HHHHHHHHHCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCC
GEIELELVPQGNLAERIRAAGAGIGGFFTRTAYGTPLAEGKETRIIDGQGYVFEKPIHAD
CCEEEEEECCCCHHHHHHHHCCCCCHHHHHHCCCCCCCCCCCEEEECCCCCEEECCCCCC
FALIKADKADRWGNLTYRKTARNFGPIMAMAAKCPIVQVSHVVELGELDPEHIVTPGLFV
EEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCHHHHCCCHHHH
KRVVKV
HHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1624453; 6780551 [H]