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The map label for this gene is acoR [H]

Identifier: 73539370

GI number: 73539370

Start: 2353335

End: 2355311

Strand: Direct

Name: acoR [H]

Synonym: Reut_B5548

Alternate gene names: 73539370

Gene position: 2353335-2355311 (Clockwise)

Preceding gene: 73539368

Following gene: 73539371

Centisome position: 86.32

GC content: 67.02

Gene sequence:

>1977_bases
ATGGACCTGCGGCAACGCGATCACATCGAGACGGTAGTCCAGGCCACCAGCTACCTGCCCCCGCCTGCCTTGCCCGCGGA
CCGGCCCACGCACGACGCCGTGATCCAGAATTCATGGCGGCGCTGCGTGCACCAGTACGGACTGGATCCTTCGCGCATGC
AGGAAGCGCGCATCCTGCCGCAGACACGCCTGCGCGAGCACCAGCAACGCATCGACGATTTCGCGCGCATTGCGCGTCAT
GGGCTGGAAAGCCTGTATGCGCAGGTGGCAGGGCTGGGCTACGTGGTGCTGCTGACCGACGCGCAGGGCGTGACCGTTGA
CTACATCGGCGACGCGCGTACCGATACCGATCTGCGCCACGCCGGCCTGTACCTGGGCGCGGAATGGAGCGAGAGCGGAG
CCGGCACCTGCGCGGTCGGCACGGCGCTGGTCACTGGCGAAGCACTGACCGTGCATCAGGCCGACCATTTCGACGCCACG
CATATTCCGCTCACTTGCACGGCGGCGCCGCTGTTCGACTCGCGCGGAAATCTCAGTGCGATCCTCGACATTTCCGCGCT
GACTTCGCCGCATGCCAAGGAGAGCCAGGGCCTGGCGCTGCAGATGGTGCGCATCTATGCGGCGCATATCGAGAATGCGA
ACTTCCTGCGCGTGCATCATCGCGACTGGATCCTCAAGCTCAACGTGGCGCCTGAGTTTGTCGACGTGAATCCGGAATAC
CTGCTCGCGCTCGACGACTGCGGCCGCATCGTCGGGCACAACCACCGCGCGCGGCGCATGCTGGAAGGGGAGCTATCCAC
TGGCACGGTGCTCGGCCAGTCGTTCGAGACGCTGTTCAACGCGCGGCTGGAAGACCTGAGCCGCTATGTCTACTCGCGCC
CGAGCGAGCAGCGGCTCGTCGCGCTGAACCGCAGTGGGGGGCTACTCTATCTGAGCGTGATGCCGCCCGCGCTGCGCTGG
CAGGCCGGCGCCCGCGAAGAACGCCTCGCGCCGTTGCCAGAGCCGCTCGCGGCATTGTGTGGCGGCGATGCCGCGCTGCA
GCAGCAATTGCAGCGCGCGGCGCGCCTGGTCGATTCGCCGATCAACCTGCTGATCAATGGCGAGACCGGCAGCGGCAAGG
AGTACTTCGCCAAGGCGCTGCATCAGGCGAGCGCCCGGCGCGGCCAGCCGTTCGTTGCAGTGAACTGCGCTGCGATTCCT
GAAACGCTGATCGAAAGCGAGCTGTTCGGCCACCTGCCCAACAGCTTCTCGGGGGCCGGTCCGCGCGGCAAGCGCGGGTT
AATCCAGGAAGCCGACGGCGGCACGCTGTTCCTCGACGAGATCGGCGACATGCCGCGCGAGCTGCAGTCGCGTCTGCTGC
GCGTGCTGGCCGAGGGCGAGGTCTTGCCGATCGGTGCGGCACGCCCGATACCGGTCAGGCTGCGCGTGATTTCCGCCACG
CATCATCGGCTGGAGGATCTGGTCGCGCAAGGACGCTTCCGCGAAGACCTGTTCTACCGGCTCAACGGCGCGCGCTTCGC
GCTGCCACCGCTGCGCGAGCGCACGGACCTTGACTGGCTAGTGCAGAAGATGCTCGACGCTGGCGGCCAGCGCGGCATCG
CGCTGTCGCCGCAGGCGCGCGAACAGCTTTGCCGCCATCGCTGGCCCGGCAACTTGCGTGAATTGCGTAACGTGCTCGAG
TACGCGCGTGCGGTCTGCTCGGACGGCTACATCGATCTGCACGACCTTCCCGATGCCCTTGGCGCTCCTGCGGCAATGAC
AGCCGTGCAGGCGCTACCCGCGCAAGAGCAAGAGGGCGACACTAAGGCGATGCCGCCGGAAGCCATGCTGCTGATGCAGT
ACCTGCGCGCGTCGGGCTGGAACCTGAGCGCGGTAGCGCGCCAGATCGGCATCAGCCGCATGACGCTGTACCGCCGCATG
GAGCGCTACGGCATCCAGTCTCCGAACCGCCGCGATGGCGAAGGGCCGCTGCAGTAG

Upstream 100 bases:

>100_bases
AGCACAGAGGCGCGCGACGACGTGTCCGGTTCGCCAGTTCGCCAAAGTGCCGCCCGCGGCGCATGGCGCAGACCGCAGCG
AAGACAACCAGGAGACAGCG

Downstream 100 bases:

>100_bases
CGCTCGCCCCGATACGGTTGTCCAGTGCTGTACACCTGCGCTGTGACACCTGTCACACCGTGAGCACCGCCAGGCCCCTT
TTGGTGGCCCTCTGACCCGC

Product: Fis-type helix-turn-helix domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 658; Mature: 658

Protein sequence:

>658_residues
MDLRQRDHIETVVQATSYLPPPALPADRPTHDAVIQNSWRRCVHQYGLDPSRMQEARILPQTRLREHQQRIDDFARIARH
GLESLYAQVAGLGYVVLLTDAQGVTVDYIGDARTDTDLRHAGLYLGAEWSESGAGTCAVGTALVTGEALTVHQADHFDAT
HIPLTCTAAPLFDSRGNLSAILDISALTSPHAKESQGLALQMVRIYAAHIENANFLRVHHRDWILKLNVAPEFVDVNPEY
LLALDDCGRIVGHNHRARRMLEGELSTGTVLGQSFETLFNARLEDLSRYVYSRPSEQRLVALNRSGGLLYLSVMPPALRW
QAGAREERLAPLPEPLAALCGGDAALQQQLQRAARLVDSPINLLINGETGSGKEYFAKALHQASARRGQPFVAVNCAAIP
ETLIESELFGHLPNSFSGAGPRGKRGLIQEADGGTLFLDEIGDMPRELQSRLLRVLAEGEVLPIGAARPIPVRLRVISAT
HHRLEDLVAQGRFREDLFYRLNGARFALPPLRERTDLDWLVQKMLDAGGQRGIALSPQAREQLCRHRWPGNLRELRNVLE
YARAVCSDGYIDLHDLPDALGAPAAMTAVQALPAQEQEGDTKAMPPEAMLLMQYLRASGWNLSAVARQIGISRMTLYRRM
ERYGIQSPNRRDGEGPLQ

Sequences:

>Translated_658_residues
MDLRQRDHIETVVQATSYLPPPALPADRPTHDAVIQNSWRRCVHQYGLDPSRMQEARILPQTRLREHQQRIDDFARIARH
GLESLYAQVAGLGYVVLLTDAQGVTVDYIGDARTDTDLRHAGLYLGAEWSESGAGTCAVGTALVTGEALTVHQADHFDAT
HIPLTCTAAPLFDSRGNLSAILDISALTSPHAKESQGLALQMVRIYAAHIENANFLRVHHRDWILKLNVAPEFVDVNPEY
LLALDDCGRIVGHNHRARRMLEGELSTGTVLGQSFETLFNARLEDLSRYVYSRPSEQRLVALNRSGGLLYLSVMPPALRW
QAGAREERLAPLPEPLAALCGGDAALQQQLQRAARLVDSPINLLINGETGSGKEYFAKALHQASARRGQPFVAVNCAAIP
ETLIESELFGHLPNSFSGAGPRGKRGLIQEADGGTLFLDEIGDMPRELQSRLLRVLAEGEVLPIGAARPIPVRLRVISAT
HHRLEDLVAQGRFREDLFYRLNGARFALPPLRERTDLDWLVQKMLDAGGQRGIALSPQAREQLCRHRWPGNLRELRNVLE
YARAVCSDGYIDLHDLPDALGAPAAMTAVQALPAQEQEGDTKAMPPEAMLLMQYLRASGWNLSAVARQIGISRMTLYRRM
ERYGIQSPNRRDGEGPLQ
>Mature_658_residues
MDLRQRDHIETVVQATSYLPPPALPADRPTHDAVIQNSWRRCVHQYGLDPSRMQEARILPQTRLREHQQRIDDFARIARH
GLESLYAQVAGLGYVVLLTDAQGVTVDYIGDARTDTDLRHAGLYLGAEWSESGAGTCAVGTALVTGEALTVHQADHFDAT
HIPLTCTAAPLFDSRGNLSAILDISALTSPHAKESQGLALQMVRIYAAHIENANFLRVHHRDWILKLNVAPEFVDVNPEY
LLALDDCGRIVGHNHRARRMLEGELSTGTVLGQSFETLFNARLEDLSRYVYSRPSEQRLVALNRSGGLLYLSVMPPALRW
QAGAREERLAPLPEPLAALCGGDAALQQQLQRAARLVDSPINLLINGETGSGKEYFAKALHQASARRGQPFVAVNCAAIP
ETLIESELFGHLPNSFSGAGPRGKRGLIQEADGGTLFLDEIGDMPRELQSRLLRVLAEGEVLPIGAARPIPVRLRVISAT
HHRLEDLVAQGRFREDLFYRLNGARFALPPLRERTDLDWLVQKMLDAGGQRGIALSPQAREQLCRHRWPGNLRELRNVLE
YARAVCSDGYIDLHDLPDALGAPAAMTAVQALPAQEQEGDTKAMPPEAMLLMQYLRASGWNLSAVARQIGISRMTLYRRM
ERYGIQSPNRRDGEGPLQ

Specific function: Required for sigma-54-dependent transcription of acoXABC [H]

COG id: COG3284

COG function: function code QK; Transcriptional activator of acetoin/glycerol metabolism

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 sigma-54 factor interaction domain [H]

Homologues:

Organism=Escherichia coli, GI1789233, Length=325, Percent_Identity=44.6153846153846, Blast_Score=249, Evalue=3e-67,
Organism=Escherichia coli, GI1790299, Length=335, Percent_Identity=40.5970149253731, Blast_Score=221, Evalue=9e-59,
Organism=Escherichia coli, GI1788905, Length=321, Percent_Identity=40.809968847352, Blast_Score=219, Evalue=3e-58,
Organism=Escherichia coli, GI1788550, Length=307, Percent_Identity=41.042345276873, Blast_Score=213, Evalue=4e-56,
Organism=Escherichia coli, GI1790437, Length=309, Percent_Identity=39.8058252427184, Blast_Score=211, Evalue=1e-55,
Organism=Escherichia coli, GI87082117, Length=331, Percent_Identity=42.2960725075529, Blast_Score=209, Evalue=5e-55,
Organism=Escherichia coli, GI1786524, Length=327, Percent_Identity=41.5902140672783, Blast_Score=202, Evalue=6e-53,
Organism=Escherichia coli, GI1789087, Length=401, Percent_Identity=33.9152119700748, Blast_Score=182, Evalue=7e-47,
Organism=Escherichia coli, GI1787583, Length=307, Percent_Identity=36.1563517915309, Blast_Score=178, Evalue=1e-45,
Organism=Escherichia coli, GI87082152, Length=312, Percent_Identity=39.1025641025641, Blast_Score=174, Evalue=1e-44,
Organism=Escherichia coli, GI87081872, Length=311, Percent_Identity=36.9774919614148, Blast_Score=167, Evalue=2e-42,
Organism=Escherichia coli, GI87081858, Length=654, Percent_Identity=25.0764525993884, Blast_Score=153, Evalue=4e-38,
Organism=Escherichia coli, GI1789828, Length=277, Percent_Identity=33.2129963898917, Blast_Score=131, Evalue=1e-31,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR020441
- InterPro:   IPR009057
- InterPro:   IPR002197
- InterPro:   IPR002078 [H]

Pfam domain/function: PF02954 HTH_8; PF00158 Sigma54_activat [H]

EC number: NA

Molecular weight: Translated: 72806; Mature: 72806

Theoretical pI: Translated: 6.89; Mature: 6.89

Prosite motif: PS00675 SIGMA54_INTERACT_1 ; PS00676 SIGMA54_INTERACT_2 ; PS00688 SIGMA54_INTERACT_3 ; PS50045 SIGMA54_INTERACT_4

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDLRQRDHIETVVQATSYLPPPALPADRPTHDAVIQNSWRRCVHQYGLDPSRMQEARILP
CCCCHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHCCC
QTRLREHQQRIDDFARIARHGLESLYAQVAGLGYVVLLTDAQGVTVDYIGDARTDTDLRH
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCEEEECCCCCCCCCHHH
AGLYLGAEWSESGAGTCAVGTALVTGEALTVHQADHFDATHIPLTCTAAPLFDSRGNLSA
CCEEEECCCCCCCCCCHHHHHHHHCCCEEEEECCCCCCCCCCCEEEEECCCCCCCCCEEE
ILDISALTSPHAKESQGLALQMVRIYAAHIENANFLRVHHRDWILKLNVAPEFVDVNPEY
EEEEHHHCCCCCCCCCCHHHHHHHHHHHHCCCCCEEEEECCCEEEEEECCCCEEECCCCE
LLALDDCGRIVGHNHRARRMLEGELSTGTVLGQSFETLFNARLEDLSRYVYSRPSEQRLV
EEEEHHHHHHHCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEE
ALNRSGGLLYLSVMPPALRWQAGAREERLAPLPEPLAALCGGDAALQQQLQRAARLVDSP
EEECCCCEEEEEECCCHHHHCCCCCCCCCCCCCHHHHHHHCCHHHHHHHHHHHHHHHCCC
INLLINGETGSGKEYFAKALHQASARRGQPFVAVNCAAIPETLIESELFGHLPNSFSGAG
CEEEEECCCCCCHHHHHHHHHHHHHHCCCCEEEEEHHHHHHHHHHHHHHHCCCCCCCCCC
PRGKRGLIQEADGGTLFLDEIGDMPRELQSRLLRVLAEGEVLPIGAARPIPVRLRVISAT
CCCCCCCCEECCCCEEEHHHHCCCHHHHHHHHHHHHHCCCEEECCCCCCCCEEEEEEHHH
HHRLEDLVAQGRFREDLFYRLNGARFALPPLRERTDLDWLVQKMLDAGGQRGIALSPQAR
HHHHHHHHHCCCHHHHHHHHCCCCEECCCCCCCCCCHHHHHHHHHHCCCCCCEEECHHHH
EQLCRHRWPGNLRELRNVLEYARAVCSDGYIDLHDLPDALGAPAAMTAVQALPAQEQEGD
HHHHHHCCCCCHHHHHHHHHHHHHHHCCCCEEHHCCCHHHCCCHHHHHHHHCCCCCCCCC
TKAMPPEAMLLMQYLRASGWNLSAVARQIGISRMTLYRRMERYGIQSPNRRDGEGPLQ
CCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCC
>Mature Secondary Structure
MDLRQRDHIETVVQATSYLPPPALPADRPTHDAVIQNSWRRCVHQYGLDPSRMQEARILP
CCCCHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHCCC
QTRLREHQQRIDDFARIARHGLESLYAQVAGLGYVVLLTDAQGVTVDYIGDARTDTDLRH
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCEEEECCCCCCCCCHHH
AGLYLGAEWSESGAGTCAVGTALVTGEALTVHQADHFDATHIPLTCTAAPLFDSRGNLSA
CCEEEECCCCCCCCCCHHHHHHHHCCCEEEEECCCCCCCCCCCEEEEECCCCCCCCCEEE
ILDISALTSPHAKESQGLALQMVRIYAAHIENANFLRVHHRDWILKLNVAPEFVDVNPEY
EEEEHHHCCCCCCCCCCHHHHHHHHHHHHCCCCCEEEEECCCEEEEEECCCCEEECCCCE
LLALDDCGRIVGHNHRARRMLEGELSTGTVLGQSFETLFNARLEDLSRYVYSRPSEQRLV
EEEEHHHHHHHCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEE
ALNRSGGLLYLSVMPPALRWQAGAREERLAPLPEPLAALCGGDAALQQQLQRAARLVDSP
EEECCCCEEEEEECCCHHHHCCCCCCCCCCCCCHHHHHHHCCHHHHHHHHHHHHHHHCCC
INLLINGETGSGKEYFAKALHQASARRGQPFVAVNCAAIPETLIESELFGHLPNSFSGAG
CEEEEECCCCCCHHHHHHHHHHHHHHCCCCEEEEEHHHHHHHHHHHHHHHCCCCCCCCCC
PRGKRGLIQEADGGTLFLDEIGDMPRELQSRLLRVLAEGEVLPIGAARPIPVRLRVISAT
CCCCCCCCEECCCCEEEHHHHCCCHHHHHHHHHHHHHCCCEEECCCCCCCCEEEEEEHHH
HHRLEDLVAQGRFREDLFYRLNGARFALPPLRERTDLDWLVQKMLDAGGQRGIALSPQAR
HHHHHHHHHCCCHHHHHHHHCCCCEECCCCCCCCCCHHHHHHHHHHCCCCCCEEECHHHH
EQLCRHRWPGNLRELRNVLEYARAVCSDGYIDLHDLPDALGAPAAMTAVQALPAQEQEGD
HHHHHHCCCCCHHHHHHHHHHHHHHHCCCCEEHHCCCHHHCCCHHHHHHHHCCCCCCCCC
TKAMPPEAMLLMQYLRASGWNLSAVARQIGISRMTLYRRMERYGIQSPNRRDGEGPLQ
CCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1378052 [H]