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The map label for this gene is kipR [H]

Identifier: 73539367

GI number: 73539367

Start: 2349424

End: 2350179

Strand: Reverse

Name: kipR [H]

Synonym: Reut_B5545

Alternate gene names: 73539367

Gene position: 2350179-2349424 (Counterclockwise)

Preceding gene: 73539369

Following gene: 73539365

Centisome position: 86.21

GC content: 67.46

Gene sequence:

>756_bases
ATGACACTCAAGACACTGGACGGCGCGCTGGCCTTGCTGACCCACTTCACCGTGCGGCAGCCGACCTGGGGCGTGCGCGA
ACTCGCCAAGCACAGCGGCGTGCACTATGCCGTGGTGCACCGCGTGCTGGCGACCTTTGCCGCCAACGGCTTCCTCGTGC
AGGACGCGGCCACCGGCAAATACTCGCTGGGCTTGCGCCTGTTCGAGCTGGGCCAGGTCGTGCGCAAGAGCTTCTCGCCC
GACGAGATCGTGCGGCCCGTGCTGGAAAAGCTGGCGGCGCAAAGCGGTGAGACGGTCTTCCTGTCATGGCTCGATGGCCA
TGAGGGGCTATGCGTTGGCCTGGTGCAAAGCCAGCACCAGTTGCGCTTTTCGATCGAACTCGGCGAGCGCTTTCCGCTGT
ATGCGGGCGCGCATGCCAAGGCCATGCTCGCCTTCCAGGACGACGCGTTCCGCGACGAGGTCTATCGACAGGGCATGGAA
AAGATGGGACCGCACACCACGCTCGACCGCGATACGATCGAAGCGCAGCTCGCCGAGGTACGCGAGCAGGGCTGGGCCCA
CACGCGCGAGGAAGCCGCCGCGACCGTGGCCGGGCTGGCGCTGCCGCTGCGGTCGCGCGACCACAGCACGGTGATTGGCT
CTGTGGCCATTGCCGGCCCGCAGCAGCGGCTTGGCGAAGACGCGGTGCCGCGCCTGCTCGAAGCCCTGCGCGATGCGAGT
GGCCGGCTCGAGGATGTGATCGGGTTCGTGCGCTGA

Upstream 100 bases:

>100_bases
CGTCGGCGTGGTTATCGCCGTGACGCCGGATCCACCGAAGGATTGAGCACAGCGCCGCTTGTCCCGTACCATGCTGCCCC
ATGCGAAGCAGGAAATCGGT

Downstream 100 bases:

>100_bases
TACCGTATCAACCGGCCAGCAACGCCTGCCCCACAGCACCGCTGAACACGCGCTGGCCGATGACGTGGCCCAGCGCGCGG
TAGCTTTCCCACTGCGCCTC

Product: regulatory protein IclR

Products: NA

Alternate protein names: Kip operon repressor protein [H]

Number of amino acids: Translated: 251; Mature: 250

Protein sequence:

>251_residues
MTLKTLDGALALLTHFTVRQPTWGVRELAKHSGVHYAVVHRVLATFAANGFLVQDAATGKYSLGLRLFELGQVVRKSFSP
DEIVRPVLEKLAAQSGETVFLSWLDGHEGLCVGLVQSQHQLRFSIELGERFPLYAGAHAKAMLAFQDDAFRDEVYRQGME
KMGPHTTLDRDTIEAQLAEVREQGWAHTREEAAATVAGLALPLRSRDHSTVIGSVAIAGPQQRLGEDAVPRLLEALRDAS
GRLEDVIGFVR

Sequences:

>Translated_251_residues
MTLKTLDGALALLTHFTVRQPTWGVRELAKHSGVHYAVVHRVLATFAANGFLVQDAATGKYSLGLRLFELGQVVRKSFSP
DEIVRPVLEKLAAQSGETVFLSWLDGHEGLCVGLVQSQHQLRFSIELGERFPLYAGAHAKAMLAFQDDAFRDEVYRQGME
KMGPHTTLDRDTIEAQLAEVREQGWAHTREEAAATVAGLALPLRSRDHSTVIGSVAIAGPQQRLGEDAVPRLLEALRDAS
GRLEDVIGFVR
>Mature_250_residues
TLKTLDGALALLTHFTVRQPTWGVRELAKHSGVHYAVVHRVLATFAANGFLVQDAATGKYSLGLRLFELGQVVRKSFSPD
EIVRPVLEKLAAQSGETVFLSWLDGHEGLCVGLVQSQHQLRFSIELGERFPLYAGAHAKAMLAFQDDAFRDEVYRQGMEK
MGPHTTLDRDTIEAQLAEVREQGWAHTREEAAATVAGLALPLRSRDHSTVIGSVAIAGPQQRLGEDAVPRLLEALRDASG
RLEDVIGFVR

Specific function: Transcriptional repressor of the kip gene-containing operon [H]

COG id: COG1414

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 iclR-ED (iclR effector binding) domain [H]

Homologues:

Organism=Escherichia coli, GI87082359, Length=230, Percent_Identity=28.2608695652174, Blast_Score=96, Evalue=3e-21,
Organism=Escherichia coli, GI1786715, Length=247, Percent_Identity=24.2914979757085, Blast_Score=94, Evalue=7e-21,
Organism=Escherichia coli, GI1788131, Length=234, Percent_Identity=28.2051282051282, Blast_Score=91, Evalue=7e-20,
Organism=Escherichia coli, GI1786468, Length=249, Percent_Identity=25.7028112449799, Blast_Score=91, Evalue=7e-20,
Organism=Escherichia coli, GI1789999, Length=248, Percent_Identity=28.6290322580645, Blast_Score=87, Evalue=7e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014757
- InterPro:   IPR005471
- InterPro:   IPR011991 [H]

Pfam domain/function: PF09339 HTH_IclR; PF01614 IclR [H]

EC number: NA

Molecular weight: Translated: 27575; Mature: 27444

Theoretical pI: Translated: 6.68; Mature: 6.68

Prosite motif: PS51077 HTH_ICLR ; PS51078 ICLR_ED

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTLKTLDGALALLTHFTVRQPTWGVRELAKHSGVHYAVVHRVLATFAANGFLVQDAATGK
CCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCHHHHHHHHHHHHHCCCEEEECCCCCC
YSLGLRLFELGQVVRKSFSPDEIVRPVLEKLAAQSGETVFLSWLDGHEGLCVGLVQSQHQ
HHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCEEEEEEECCCCCEEEHHHHCCCC
LRFSIELGERFPLYAGAHAKAMLAFQDDAFRDEVYRQGMEKMGPHTTLDRDTIEAQLAEV
EEEEEEECCCCCCEECCCHHEEEEECCHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHH
REQGWAHTREEAAATVAGLALPLRSRDHSTVIGSVAIAGPQQRLGEDAVPRLLEALRDAS
HHHCCCHHHHHHHHHHHHHHHHCCCCCCCHHEEHEEECCCHHHHCHHHHHHHHHHHHHCC
GRLEDVIGFVR
CHHHHHHHHCC
>Mature Secondary Structure 
TLKTLDGALALLTHFTVRQPTWGVRELAKHSGVHYAVVHRVLATFAANGFLVQDAATGK
CCCHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCHHHHHHHHHHHHHCCCEEEECCCCCC
YSLGLRLFELGQVVRKSFSPDEIVRPVLEKLAAQSGETVFLSWLDGHEGLCVGLVQSQHQ
HHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCEEEEEEECCCCCEEEHHHHCCCC
LRFSIELGERFPLYAGAHAKAMLAFQDDAFRDEVYRQGMEKMGPHTTLDRDTIEAQLAEV
EEEEEEECCCCCCEECCCHHEEEEECCHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHH
REQGWAHTREEAAATVAGLALPLRSRDHSTVIGSVAIAGPQQRLGEDAVPRLLEALRDAS
HHHCCCHHHHHHHHHHHHHHHHCCCCCCCHHEEHEEECCCHHHHCHHHHHHHHHHHHHCC
GRLEDVIGFVR
CHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8969502; 9384377 [H]