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The map label for this gene is kipR [H]

Identifier: 73539365

GI number: 73539365

Start: 2345741

End: 2346466

Strand: Reverse

Name: kipR [H]

Synonym: Reut_B5543

Alternate gene names: 73539365

Gene position: 2346466-2345741 (Counterclockwise)

Preceding gene: 73539367

Following gene: 73539364

Centisome position: 86.07

GC content: 68.32

Gene sequence:

>726_bases
ATGCTCAAGACCCTCGATGGCGCACTGGCGCTGTTGACCCATTTCAATGCGCGCCAGCCAAGCTGGGGCGTGCGCGAACT
CGCCCGTGAAAGCGGCGTGCACCACGCGGTGGTCCACCGCGTGCTGGCGACGTTCGCCGCCAACGGCTTCCTGGTGCAGG
ACGCCGCCGGCCGCTATGGCCTTGGGCTGCGCTGGTTCGAACTCGGTCAGGTCATGCGCAAGACCTTCACGCCGGCCGAA
GTCGTGCAGCCCGCGCTGGAAGCGCTGGCGAGGCAGAGCGGGGAAACCGTGTTCCTGTCGTGGCTCGATGGCGAGGAGGG
CCTGTGCACGGACATCGCCCATAGCCAGCATCAGTTGCGCTTTTCGATTGAGGTCGGCCAGCGCTTCGCGCTGGATGCCG
GCGCGCATGCCAAGGCGATCCTGGCGTTCCAGCCGGAATCCCTGCGCGAGCGCGTGGCGCACCGCGCGGGCCTGTCCGTG
CAGGAGCTGGAAGCACGCCTCGCGCGGGTCCGCAGCGATGGCTGGTCCTATACCTGCGAGGAATCCACGGCCACCGTGGC
GGGCCTGGCAGTACCGCTGTACAGCCGAGATACGCGAACCGTAATCGGTTCGCTGGCGATTGCAGGTCCGCTGCAGCGCC
TGGACGAACAAGCCCTGCCGCGCCTGCTCGATGCGCTGCGGGCCGCACGCGACACCATCGGGCCGGTGACGGGATTCCTG
CGCTGA

Upstream 100 bases:

>100_bases
TTATCCGCGTTAACCCTGATTGTTCGGTAGGCCTACCGACGCCTAGCATTTCTCTCTATCAGAGACGTTGTCTCTATATA
AGAGACACAAGGCAGTCGAA

Downstream 100 bases:

>100_bases
CAACACACGGCGCGCCACCGGCCGGGCTGGCAGGGCGCGCGAAACGAGACAACACTAGGGAGGAAAGGTAGACATGACGC
CTATGCAAACAGAACTGAAC

Product: regulatory protein IclR

Products: NA

Alternate protein names: Kip operon repressor protein [H]

Number of amino acids: Translated: 241; Mature: 241

Protein sequence:

>241_residues
MLKTLDGALALLTHFNARQPSWGVRELARESGVHHAVVHRVLATFAANGFLVQDAAGRYGLGLRWFELGQVMRKTFTPAE
VVQPALEALARQSGETVFLSWLDGEEGLCTDIAHSQHQLRFSIEVGQRFALDAGAHAKAILAFQPESLRERVAHRAGLSV
QELEARLARVRSDGWSYTCEESTATVAGLAVPLYSRDTRTVIGSLAIAGPLQRLDEQALPRLLDALRAARDTIGPVTGFL
R

Sequences:

>Translated_241_residues
MLKTLDGALALLTHFNARQPSWGVRELARESGVHHAVVHRVLATFAANGFLVQDAAGRYGLGLRWFELGQVMRKTFTPAE
VVQPALEALARQSGETVFLSWLDGEEGLCTDIAHSQHQLRFSIEVGQRFALDAGAHAKAILAFQPESLRERVAHRAGLSV
QELEARLARVRSDGWSYTCEESTATVAGLAVPLYSRDTRTVIGSLAIAGPLQRLDEQALPRLLDALRAARDTIGPVTGFL
R
>Mature_241_residues
MLKTLDGALALLTHFNARQPSWGVRELARESGVHHAVVHRVLATFAANGFLVQDAAGRYGLGLRWFELGQVMRKTFTPAE
VVQPALEALARQSGETVFLSWLDGEEGLCTDIAHSQHQLRFSIEVGQRFALDAGAHAKAILAFQPESLRERVAHRAGLSV
QELEARLARVRSDGWSYTCEESTATVAGLAVPLYSRDTRTVIGSLAIAGPLQRLDEQALPRLLDALRAARDTIGPVTGFL
R

Specific function: Transcriptional repressor of the kip gene-containing operon [H]

COG id: COG1414

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 iclR-ED (iclR effector binding) domain [H]

Homologues:

Organism=Escherichia coli, GI87082359, Length=227, Percent_Identity=27.7533039647577, Blast_Score=83, Evalue=1e-17,
Organism=Escherichia coli, GI1786468, Length=248, Percent_Identity=23.7903225806452, Blast_Score=75, Evalue=5e-15,
Organism=Escherichia coli, GI1788131, Length=227, Percent_Identity=25.9911894273128, Blast_Score=67, Evalue=9e-13,
Organism=Escherichia coli, GI1789999, Length=244, Percent_Identity=27.4590163934426, Blast_Score=64, Evalue=9e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014757
- InterPro:   IPR005471
- InterPro:   IPR011991 [H]

Pfam domain/function: PF09339 HTH_IclR; PF01614 IclR [H]

EC number: NA

Molecular weight: Translated: 26329; Mature: 26329

Theoretical pI: Translated: 7.74; Mature: 7.74

Prosite motif: PS51077 HTH_ICLR ; PS51078 ICLR_ED

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLKTLDGALALLTHFNARQPSWGVRELARESGVHHAVVHRVLATFAANGFLVQDAAGRYG
CCCCHHHHHHHHHHCCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHCCCEEEECCCCCCC
LGLRWFELGQVMRKTFTPAEVVQPALEALARQSGETVFLSWLDGEEGLCTDIAHSQHQLR
CCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCHHHHHCCHHHEE
FSIEVGQRFALDAGAHAKAILAFQPESLRERVAHRAGLSVQELEARLARVRSDGWSYTCE
EEEECCCEEECCCCCCCEEEEEECCHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCEEEC
ESTATVAGLAVPLYSRDTRTVIGSLAIAGPLQRLDEQALPRLLDALRAARDTIGPVTGFL
CCCHHHHHHEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
R
C
>Mature Secondary Structure
MLKTLDGALALLTHFNARQPSWGVRELARESGVHHAVVHRVLATFAANGFLVQDAAGRYG
CCCCHHHHHHHHHHCCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHCCCEEEECCCCCCC
LGLRWFELGQVMRKTFTPAEVVQPALEALARQSGETVFLSWLDGEEGLCTDIAHSQHQLR
CCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCHHHHHCCHHHEE
FSIEVGQRFALDAGAHAKAILAFQPESLRERVAHRAGLSVQELEARLARVRSDGWSYTCE
EEEECCCEEECCCCCCCEEEEEECCHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCEEEC
ESTATVAGLAVPLYSRDTRTVIGSLAIAGPLQRLDEQALPRLLDALRAARDTIGPVTGFL
CCCHHHHHHEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
R
C

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8969502; 9384377 [H]