| Definition | Ralstonia eutropha JMP134 chromosome chromosome 2, complete sequence. |
|---|---|
| Accession | NC_007348 |
| Length | 2,726,152 |
Click here to switch to the map view.
The map label for this gene is ada [H]
Identifier: 73539138
GI number: 73539138
Start: 2078121
End: 2079650
Strand: Reverse
Name: ada [H]
Synonym: Reut_B5315
Alternate gene names: 73539138
Gene position: 2079650-2078121 (Counterclockwise)
Preceding gene: 73539141
Following gene: 73539137
Centisome position: 76.29
GC content: 67.97
Gene sequence:
>1530_bases ATGGAACTCGATCCCGACACCTGCTACAAGGCCGTGGCCTCGCATGACCGGCGCTTCGATGGCCGCTTCTTCGTCGGCGT GTCGTCCACGGGCATCTACTGCCGGCCCGTGTGCGCGGTGCGTACCCCGAAGCGCGAGAACTGCACGTTCTACGAAAGCG CCGCGGCGGCGGAGAAACACGGCTTTCGCCCCTGCCTACGCTGCCGCCCGGAACTCGCGCCGGGCCATGGGCTGGCCGAT ATCTCGGGCCGCCTCGCGCAAGCTGCCGCAACGCTGATCGACGAAGGCTTCATGGCCGATGCCGGCGTGGCTGCGCTTGC CGCACGCATCGGCGTGACCGAACGCCATCTGCATCGACTGTTCACCGCGCAGTTTGGTGTCTCGGTGCTCGAGTACGTGC AGACGCAGCGCCTGCTGCTGGCCAAGCGGCTGCTGACCGATACCGCGCTGCCCGTCACCGAAGTGGCGCTGGCCGCTGGT TTTGGCAGCGTGCGGCGCTTCAACGACGTGCTGCGCACGCGCTATGGCCTCACGCCCATGGCATTGCGCAAGCGCGCGTC GGACGGCGTGGCTGACCGGCTGGTGTTCGAACTCGGCTACCGGCCGCCGCTCGCATGGGAGGCGCTGCTGGGCTTTCTGG CGGTGCGCGCGGTCGATGGCATCGAGCAAGTGCGCGATGGCGCGTATGCGCGCACGCTGTCGGTCGAGAGCGGCGGCACC ACGCATCGCGGCTGGGTGCGCCTTGATCATGTGCCGGGGCGGCTCGTGTTGCGCGTGACATTGTCGGCGTCGCTCGCGCG CGTGATTCCGCAAGCGCTGGGCAAGGTGCGCCGGCTTTGCGACCTTGGCTGCCGGCCCGATATTGTCGACCGCCACCTTG GTGAGCTGGCCAGCGATGTGCCGGGCATGCGGCTGCCGGGCAGTGTCGACGGGTTCGAGATCGCCGTGCGCGCCGTGATC GGCCAGGTGATCTCGGTGGTGCAGGCGCGGCGCATCCTGGCGCGGCTCGGACAGACCGCAGGCGATGCCCTGCCGGCGCC CGCCATGCCGATCGACGGATGCGCGCCGCTGCAACATGGCTTTCCATCCGCCGCTGCGCTGGCAGCATTGCCGGATGCAG ACATGGTTGCCGCCGGCGTGTCACCGGGCAAGCTGCGTACACTGCGCGCACTTGCGCAACGCGTTGCCAGCGGTGCGCTT CCGCTGGAGCAGCACATGCCGCCCGAGCAGACCGTGGCGGCGCTGTGCGAGATTGACGGGATCGGCGACTGGACTGCGCA GTACGTCGCGATGCGCGCATTGGGCTGGCCTGACGCGTTCCCGGGGACCGACTACGCGTTGCGCAAGGTACTCGGCGTGA ACACCGTACGGGCCATGCAGGCGCGTACGGCGCAGTGGGCACCATGGCGCGCCTATGCGGCCATCCACTTGTGGCATCGC TATGAAGCGATGAAAACGCAAGGTGACGGCGCAGTGATACCTTTGCCCGACATAATTGCCAGCCATTCCGATATCGAGGT GACGACATGA
Upstream 100 bases:
>100_bases AGTCCATTGCCGTAACTGTGCCCCATGGCACGGTCGAAGGCCACAGGGGAATGTCCGAATCCAGCGGGTGCCTGGGTGCC TGACGCGGTAGCATGCACGC
Downstream 100 bases:
>100_bases TCAGCTACCGCCAGATCGACAGCCCGCTCGGCGCCATGCTGTTGCGTGTGCAGGACAGCTTCCTGACGGGCGTTTATTTC GAGGGGCAGAAGTACTATCC
Product: transcriptional regulator Ada
Products: NA
Alternate protein names: Regulatory protein of adaptative response; Methylated-DNA--protein-cysteine methyltransferase; O-6-methylguanine-DNA alkyltransferase [H]
Number of amino acids: Translated: 509; Mature: 509
Protein sequence:
>509_residues MELDPDTCYKAVASHDRRFDGRFFVGVSSTGIYCRPVCAVRTPKRENCTFYESAAAAEKHGFRPCLRCRPELAPGHGLAD ISGRLAQAAATLIDEGFMADAGVAALAARIGVTERHLHRLFTAQFGVSVLEYVQTQRLLLAKRLLTDTALPVTEVALAAG FGSVRRFNDVLRTRYGLTPMALRKRASDGVADRLVFELGYRPPLAWEALLGFLAVRAVDGIEQVRDGAYARTLSVESGGT THRGWVRLDHVPGRLVLRVTLSASLARVIPQALGKVRRLCDLGCRPDIVDRHLGELASDVPGMRLPGSVDGFEIAVRAVI GQVISVVQARRILARLGQTAGDALPAPAMPIDGCAPLQHGFPSAAALAALPDADMVAAGVSPGKLRTLRALAQRVASGAL PLEQHMPPEQTVAALCEIDGIGDWTAQYVAMRALGWPDAFPGTDYALRKVLGVNTVRAMQARTAQWAPWRAYAAIHLWHR YEAMKTQGDGAVIPLPDIIASHSDIEVTT
Sequences:
>Translated_509_residues MELDPDTCYKAVASHDRRFDGRFFVGVSSTGIYCRPVCAVRTPKRENCTFYESAAAAEKHGFRPCLRCRPELAPGHGLAD ISGRLAQAAATLIDEGFMADAGVAALAARIGVTERHLHRLFTAQFGVSVLEYVQTQRLLLAKRLLTDTALPVTEVALAAG FGSVRRFNDVLRTRYGLTPMALRKRASDGVADRLVFELGYRPPLAWEALLGFLAVRAVDGIEQVRDGAYARTLSVESGGT THRGWVRLDHVPGRLVLRVTLSASLARVIPQALGKVRRLCDLGCRPDIVDRHLGELASDVPGMRLPGSVDGFEIAVRAVI GQVISVVQARRILARLGQTAGDALPAPAMPIDGCAPLQHGFPSAAALAALPDADMVAAGVSPGKLRTLRALAQRVASGAL PLEQHMPPEQTVAALCEIDGIGDWTAQYVAMRALGWPDAFPGTDYALRKVLGVNTVRAMQARTAQWAPWRAYAAIHLWHR YEAMKTQGDGAVIPLPDIIASHSDIEVTT >Mature_509_residues MELDPDTCYKAVASHDRRFDGRFFVGVSSTGIYCRPVCAVRTPKRENCTFYESAAAAEKHGFRPCLRCRPELAPGHGLAD ISGRLAQAAATLIDEGFMADAGVAALAARIGVTERHLHRLFTAQFGVSVLEYVQTQRLLLAKRLLTDTALPVTEVALAAG FGSVRRFNDVLRTRYGLTPMALRKRASDGVADRLVFELGYRPPLAWEALLGFLAVRAVDGIEQVRDGAYARTLSVESGGT THRGWVRLDHVPGRLVLRVTLSASLARVIPQALGKVRRLCDLGCRPDIVDRHLGELASDVPGMRLPGSVDGFEIAVRAVI GQVISVVQARRILARLGQTAGDALPAPAMPIDGCAPLQHGFPSAAALAALPDADMVAAGVSPGKLRTLRALAQRVASGAL PLEQHMPPEQTVAALCEIDGIGDWTAQYVAMRALGWPDAFPGTDYALRKVLGVNTVRAMQARTAQWAPWRAYAAIHLWHR YEAMKTQGDGAVIPLPDIIASHSDIEVTT
Specific function: The methylated ADA protein acts as a positive regulator of its own synthesis, as well as that of other proteins. The transcription-activating function of the ADA protein resides in its N-terminus [H]
COG id: COG0122
COG function: function code L; 3-methyladenine DNA glycosylase/8-oxoguanine DNA glycosylase
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Contains 1 HTH araC/xylS-type DNA-binding domain [H]
Homologues:
Organism=Escherichia coli, GI1788383, Length=285, Percent_Identity=37.1929824561403, Blast_Score=167, Evalue=1e-42, Organism=Escherichia coli, GI1788542, Length=185, Percent_Identity=34.5945945945946, Blast_Score=88, Evalue=1e-18,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR004026 - InterPro: IPR010316 - InterPro: IPR011257 - InterPro: IPR003265 - InterPro: IPR003583 - InterPro: IPR009057 - InterPro: IPR012287 - InterPro: IPR018062 - InterPro: IPR018060 - InterPro: IPR023170 - InterPro: IPR012294 [H]
Pfam domain/function: PF02805 Ada_Zn_binding; PF06029 AlkA_N; PF00730 HhH-GPD [H]
EC number: =2.1.1.63 [H]
Molecular weight: Translated: 54846; Mature: 54846
Theoretical pI: Translated: 8.82; Mature: 8.82
Prosite motif: PS01124 HTH_ARAC_FAMILY_2
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
2.0 %Cys (Translated Protein) 2.0 %Met (Translated Protein) 3.9 %Cys+Met (Translated Protein) 2.0 %Cys (Mature Protein) 2.0 %Met (Mature Protein) 3.9 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MELDPDTCYKAVASHDRRFDGRFFVGVSSTGIYCRPVCAVRTPKRENCTFYESAAAAEKH CCCCHHHHHHHHHHCCCCCCCEEEEEECCCCEEEECCHHCCCCCCCCCCHHHHHHHHHHC GFRPCLRCRPELAPGHGLADISGRLAQAAATLIDEGFMADAGVAALAARIGVTERHLHRL CCCHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCHHHHHHHH FTAQFGVSVLEYVQTQRLLLAKRLLTDTALPVTEVALAAGFGSVRRFNDVLRTRYGLTPM HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCHHHHHHHHHHHHHCCCCHH ALRKRASDGVADRLVFELGYRPPLAWEALLGFLAVRAVDGIEQVRDGAYARTLSVESGGT HHHHHHCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCC THRGWVRLDHVPGRLVLRVTLSASLARVIPQALGKVRRLCDLGCRPDIVDRHLGELASDV CCCCCEEEECCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCC PGMRLPGSVDGFEIAVRAVIGQVISVVQARRILARLGQTAGDALPAPAMPIDGCAPLQHG CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHCC FPSAAALAALPDADMVAAGVSPGKLRTLRALAQRVASGALPLEQHMPPEQTVAALCEIDG CCCHHHHHHCCCCHHHCCCCCCHHHHHHHHHHHHHHHCCCCHHHCCCHHHHHHHHHHHCC IGDWTAQYVAMRALGWPDAFPGTDYALRKVLGVNTVRAMQARTAQWAPWRAYAAIHLWHR CCHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHH YEAMKTQGDGAVIPLPDIIASHSDIEVTT HHHHHCCCCCCEECCHHHHCCCCCCEECC >Mature Secondary Structure MELDPDTCYKAVASHDRRFDGRFFVGVSSTGIYCRPVCAVRTPKRENCTFYESAAAAEKH CCCCHHHHHHHHHHCCCCCCCEEEEEECCCCEEEECCHHCCCCCCCCCCHHHHHHHHHHC GFRPCLRCRPELAPGHGLADISGRLAQAAATLIDEGFMADAGVAALAARIGVTERHLHRL CCCHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCHHHHHHHH FTAQFGVSVLEYVQTQRLLLAKRLLTDTALPVTEVALAAGFGSVRRFNDVLRTRYGLTPM HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCHHHHHHHHHHHHHCCCCHH ALRKRASDGVADRLVFELGYRPPLAWEALLGFLAVRAVDGIEQVRDGAYARTLSVESGGT HHHHHHCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCC THRGWVRLDHVPGRLVLRVTLSASLARVIPQALGKVRRLCDLGCRPDIVDRHLGELASDV CCCCCEEEECCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCC PGMRLPGSVDGFEIAVRAVIGQVISVVQARRILARLGQTAGDALPAPAMPIDGCAPLQHG CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHCC FPSAAALAALPDADMVAAGVSPGKLRTLRALAQRVASGALPLEQHMPPEQTVAALCEIDG CCCHHHHHHCCCCHHHCCCCCCHHHHHHHHHHHHHHHCCCCHHHCCCHHHHHHHHHHHCC IGDWTAQYVAMRALGWPDAFPGTDYALRKVLGVNTVRAMQARTAQWAPWRAYAAIHLWHR CCHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHH YEAMKTQGDGAVIPLPDIIASHSDIEVTT HHHHHCCCCCCEECCHHHHCCCCCCEECC
PDB accession: NA
Resolution: NA
Structure class: Unstructured
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 9.0
TargetDB status: NA
Availability: NA
References: 9634230; 12218036 [H]