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The map label for this gene is yybE [H]

Identifier: 73539133

GI number: 73539133

Start: 2074034

End: 2074924

Strand: Direct

Name: yybE [H]

Synonym: Reut_B5310

Alternate gene names: 73539133

Gene position: 2074034-2074924 (Clockwise)

Preceding gene: 73539128

Following gene: 73539134

Centisome position: 76.08

GC content: 69.7

Gene sequence:

>891_bases
ATGGAGACACGGGATATCGAATACATCCTGGCCGTGGAGCGGTGCTGCGGCATCGGCCGAGCGGCGGAGTCGCTGGGCAT
CACCCAGCCGGCGCTGACCAAGGCGGTGCAGCGCGTCGAGGCGCAGGTTGGCGTGCCGCTGTTCGAGCGCACGGCCAATG
GCATGAGCACCACGCAAGCGGGTCGGCACTTTATCGAGCGCGCGCGCCGCATCCAGCTCGAATACGAGGATGCGCTCAAG
GAGATGCAGGGGATCCGCACCGGCGAGTTGGGCGTGCTGCGGCTCGGATACTCGCCGTCGCTGCCCAATTCGATCGTGCT
GGACGCCTGCCGCAGGCTGCTGAAGGAGCGCCCGGTGGCCCGTCTGCGTCTGCGCCGCCGCCTGGCGCGCGACCTGATGG
ACCTGCTCACGGCCGGCGAACTGGATCTTGCCGTAGCGCCCGTACCGAGGCAGGCCACCGACATCCTGGCCATTGAAGAG
CTGTTCGACGACCGCCTCGTGGTGGTGGCCGATGAAGCTCATCCGCTGCAGCAGCGGCGCAACCTGCGCCTGGCCGACCT
GTGCGGCCAGGAATGGCTGCTGCCGGAGGGCCATATCGTGCTGCGCCAGCAGGTCGACGAGGCCTTCCGCCGGCAAGGGC
TGCCGCCGCCGGCGATGCGGGTGGAAGTGGACTTCGGCACCGCATCGCTTTTTGGGCTGATCCGTGGCACGCCCATGCTG
AGCGTATCGAGCGGCCACGCCGAGGCCGGGCTGCCGGGCCTGAAGCCGCTCGACGTGGGGCTGGACGAACTCGACTTGCG
GCGGCGCATCGGCGTGGTGACGCGCGCCGGCGCCTACCTGTCGCCGCTGGCGCAACGCATGGCCGCGCTGCTGCGCGAAC
AGGTCGGGTGA

Upstream 100 bases:

>100_bases
TCGGCGTCTCCATGCTGTATGTCTGGTGGAGTCTGTAAGATGAGCGCCATCACCACAATGCAGGCTTGGCTATAAAGTCA
TAACCAACAGGAATGCTGGC

Downstream 100 bases:

>100_bases
CCGACTGAGCGGACTGCCGGGAATGGGCCTTACCTCCAAGCTGGCAGAGTCGCTTTCGGCGCTGAAACACCGGGTGTACA
GGGCGTCTTTGCCCCAGTGC

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 296; Mature: 296

Protein sequence:

>296_residues
METRDIEYILAVERCCGIGRAAESLGITQPALTKAVQRVEAQVGVPLFERTANGMSTTQAGRHFIERARRIQLEYEDALK
EMQGIRTGELGVLRLGYSPSLPNSIVLDACRRLLKERPVARLRLRRRLARDLMDLLTAGELDLAVAPVPRQATDILAIEE
LFDDRLVVVADEAHPLQQRRNLRLADLCGQEWLLPEGHIVLRQQVDEAFRRQGLPPPAMRVEVDFGTASLFGLIRGTPML
SVSSGHAEAGLPGLKPLDVGLDELDLRRRIGVVTRAGAYLSPLAQRMAALLREQVG

Sequences:

>Translated_296_residues
METRDIEYILAVERCCGIGRAAESLGITQPALTKAVQRVEAQVGVPLFERTANGMSTTQAGRHFIERARRIQLEYEDALK
EMQGIRTGELGVLRLGYSPSLPNSIVLDACRRLLKERPVARLRLRRRLARDLMDLLTAGELDLAVAPVPRQATDILAIEE
LFDDRLVVVADEAHPLQQRRNLRLADLCGQEWLLPEGHIVLRQQVDEAFRRQGLPPPAMRVEVDFGTASLFGLIRGTPML
SVSSGHAEAGLPGLKPLDVGLDELDLRRRIGVVTRAGAYLSPLAQRMAALLREQVG
>Mature_296_residues
METRDIEYILAVERCCGIGRAAESLGITQPALTKAVQRVEAQVGVPLFERTANGMSTTQAGRHFIERARRIQLEYEDALK
EMQGIRTGELGVLRLGYSPSLPNSIVLDACRRLLKERPVARLRLRRRLARDLMDLLTAGELDLAVAPVPRQATDILAIEE
LFDDRLVVVADEAHPLQQRRNLRLADLCGQEWLLPEGHIVLRQQVDEAFRRQGLPPPAMRVEVDFGTASLFGLIRGTPML
SVSSGHAEAGLPGLKPLDVGLDELDLRRRIGVVTRAGAYLSPLAQRMAALLREQVG

Specific function: Positive Regulatory Protein For The Cyn Operon. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI157672245, Length=260, Percent_Identity=25.7692307692308, Blast_Score=91, Evalue=7e-20,
Organism=Escherichia coli, GI1790399, Length=308, Percent_Identity=28.2467532467532, Blast_Score=90, Evalue=2e-19,
Organism=Escherichia coli, GI1787879, Length=203, Percent_Identity=28.5714285714286, Blast_Score=83, Evalue=2e-17,
Organism=Escherichia coli, GI1789506, Length=233, Percent_Identity=24.8927038626609, Blast_Score=78, Evalue=7e-16,
Organism=Escherichia coli, GI145693105, Length=301, Percent_Identity=23.2558139534884, Blast_Score=78, Evalue=7e-16,
Organism=Escherichia coli, GI1788887, Length=203, Percent_Identity=33.0049261083744, Blast_Score=72, Evalue=6e-14,
Organism=Escherichia coli, GI2367136, Length=255, Percent_Identity=24.3137254901961, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1787530, Length=219, Percent_Identity=22.8310502283105, Blast_Score=66, Evalue=3e-12,
Organism=Escherichia coli, GI87081904, Length=297, Percent_Identity=25.9259259259259, Blast_Score=65, Evalue=5e-12,
Organism=Escherichia coli, GI1788297, Length=259, Percent_Identity=26.2548262548263, Blast_Score=64, Evalue=8e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 32786; Mature: 32786

Theoretical pI: Translated: 7.97; Mature: 7.97

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
METRDIEYILAVERCCGIGRAAESLGITQPALTKAVQRVEAQVGVPLFERTANGMSTTQA
CCCCHHHHHHHHHHHHCCCHHHHHCCCCCHHHHHHHHHHHHHHCCHHHHHHCCCCHHHHH
GRHFIERARRIQLEYEDALKEMQGIRTGELGVLRLGYSPSLPNSIVLDACRRLLKERPVA
HHHHHHHHHHCCCHHHHHHHHHHCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHCCHH
RLRLRRRLARDLMDLLTAGELDLAVAPVPRQATDILAIEELFDDRLVVVADEAHPLQQRR
HHHHHHHHHHHHHHHHHCCCCCEEECCCCCHHHHHHHHHHHHCCCEEEEECCCCHHHHHC
NLRLADLCGQEWLLPEGHIVLRQQVDEAFRRQGLPPPAMRVEVDFGTASLFGLIRGTPML
CCCHHHHCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCEEEEEECCHHHHHHHHHCCCEE
SVSSGHAEAGLPGLKPLDVGLDELDLRRRIGVVTRAGAYLSPLAQRMAALLREQVG
EECCCCCCCCCCCCCCHHCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
METRDIEYILAVERCCGIGRAAESLGITQPALTKAVQRVEAQVGVPLFERTANGMSTTQA
CCCCHHHHHHHHHHHHCCCHHHHHCCCCCHHHHHHHHHHHHHHCCHHHHHHCCCCHHHHH
GRHFIERARRIQLEYEDALKEMQGIRTGELGVLRLGYSPSLPNSIVLDACRRLLKERPVA
HHHHHHHHHHCCCHHHHHHHHHHCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHCCHH
RLRLRRRLARDLMDLLTAGELDLAVAPVPRQATDILAIEELFDDRLVVVADEAHPLQQRR
HHHHHHHHHHHHHHHHHCCCCCEEECCCCCHHHHHHHHHHHHCCCEEEEECCCCHHHHHC
NLRLADLCGQEWLLPEGHIVLRQQVDEAFRRQGLPPPAMRVEVDFGTASLFGLIRGTPML
CCCHHHHCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCEEEEEECCHHHHHHHHHCCCEE
SVSSGHAEAGLPGLKPLDVGLDELDLRRRIGVVTRAGAYLSPLAQRMAALLREQVG
EECCCCCCCCCCCCCCHHCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7584024; 9384377 [H]