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The map label for this gene is pntAB [H]

Identifier: 73539114

GI number: 73539114

Start: 2053521

End: 2053886

Strand: Reverse

Name: pntAB [H]

Synonym: Reut_B5291

Alternate gene names: 73539114

Gene position: 2053886-2053521 (Counterclockwise)

Preceding gene: 73539115

Following gene: 73539113

Centisome position: 75.34

GC content: 64.48

Gene sequence:

>366_bases
ATGGAAATGGTGAACCACACGGTGATCAACCTGATCATCTTCGTGCTGGCGATCTACGTGGGCTACCACGTGGTGTGGAC
GGTCACGCCCGCGCTGCACACGCCGCTGATGGCGGTAACCAATGCAATCTCGGCCATCATCATCGTCGGCGCGATGCTGG
CCGCTGGCCTGACTGAAGGCGGCGTGGGCCGCGCGATGGGCACGCTTGCGGTGGCACTGGCTGCGGTCAACGTGTTCGGC
GGCTTCCTCGTCACGCAACGCATGCTAGAGATGTTCCGCAAGAAGGCGCCGAAGGTGAAGGCCGAGGCGCAGCCCGCAAA
GACGCCCGCGCACGCCGGCGGAGAACTGGTGGAGATGCCGCGATGA

Upstream 100 bases:

>100_bases
AAGGACGGCCAGTTCTCGCTCAACCTCGAAGACGACATCGTCGCGGCTTGCCTGATGACGCGGCGCGAAGAAGCGGCGCT
GGCCGGTTAAGGAGACAACC

Downstream 100 bases:

>100_bases
ACGGACTGTCCATGAATACCGTGACGCTGTTCTACCTGGGCGCGTCAGTCTGCTTTATCCAGGCCCTCAAAGGGCTTTCG
CACCCGGCTTCGGCCCGCAA

Product: NAD(P) transhydrogenase subunit alpha

Products: NA

Alternate protein names: Nicotinamide nucleotide transhydrogenase subunit alpha 2; Proton-translocating transhydrogenase component 2; Pyridine nucleotide transhydrogenase subunit alpha 2; dII [H]

Number of amino acids: Translated: 121; Mature: 121

Protein sequence:

>121_residues
MEMVNHTVINLIIFVLAIYVGYHVVWTVTPALHTPLMAVTNAISAIIIVGAMLAAGLTEGGVGRAMGTLAVALAAVNVFG
GFLVTQRMLEMFRKKAPKVKAEAQPAKTPAHAGGELVEMPR

Sequences:

>Translated_121_residues
MEMVNHTVINLIIFVLAIYVGYHVVWTVTPALHTPLMAVTNAISAIIIVGAMLAAGLTEGGVGRAMGTLAVALAAVNVFG
GFLVTQRMLEMFRKKAPKVKAEAQPAKTPAHAGGELVEMPR
>Mature_121_residues
MEMVNHTVINLIIFVLAIYVGYHVVWTVTPALHTPLMAVTNAISAIIIVGAMLAAGLTEGGVGRAMGTLAVALAAVNVFG
GFLVTQRMLEMFRKKAPKVKAEAQPAKTPAHAGGELVEMPR

Specific function: The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane [H]

COG id: COG3288

COG function: function code C; NAD/NADP transhydrogenase alpha subunit

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI122939155, Length=83, Percent_Identity=53.0120481927711, Blast_Score=88, Evalue=2e-18,
Organism=Homo sapiens, GI122939153, Length=83, Percent_Identity=53.0120481927711, Blast_Score=88, Evalue=2e-18,
Organism=Escherichia coli, GI1787887, Length=86, Percent_Identity=58.1395348837209, Blast_Score=101, Evalue=2e-23,
Organism=Caenorhabditis elegans, GI17550456, Length=84, Percent_Identity=53.5714285714286, Blast_Score=91, Evalue=2e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: =1.6.1.2 [H]

Molecular weight: Translated: 12765; Mature: 12765

Theoretical pI: Translated: 10.16; Mature: 10.16

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
6.6 %Met     (Translated Protein)
6.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
6.6 %Met     (Mature Protein)
6.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEMVNHTVINLIIFVLAIYVGYHVVWTVTPALHTPLMAVTNAISAIIIVGAMLAAGLTEG
CCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
GVGRAMGTLAVALAAVNVFGGFLVTQRMLEMFRKKAPKVKAEAQPAKTPAHAGGELVEMP
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCC
R
C
>Mature Secondary Structure
MEMVNHTVINLIIFVLAIYVGYHVVWTVTPALHTPLMAVTNAISAIIIVGAMLAAGLTEG
CCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
GVGRAMGTLAVALAAVNVFGGFLVTQRMLEMFRKKAPKVKAEAQPAKTPAHAGGELVEMP
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCC
R
C

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8075801 [H]