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The map label for this gene is sdsB [H]

Identifier: 73539073

GI number: 73539073

Start: 1999144

End: 2000082

Strand: Reverse

Name: sdsB [H]

Synonym: Reut_B5250

Alternate gene names: 73539073

Gene position: 2000082-1999144 (Counterclockwise)

Preceding gene: 73539076

Following gene: 73539069

Centisome position: 73.37

GC content: 68.69

Gene sequence:

>939_bases
ATGCTCAGCTTGCGTCGTCTCGAGCATTTCGCGGTGCTGGCCGAAGAGCGCAGCTTCTCGCGCGCCGCGCGCCGGCTCAA
CCTGACCCAGCCGGCGCTGACGCGCAGCATCCAGACGCTCGAGGAAACGCTGGAGCTTCAACTGGTGGACCGTGCCGCGA
GCGGGCTGGTGCTGACGGAAGCCGGCGCAATGGTGCTGGAGCGTTCACGCCGCATGCTCGGCGATGTGCGTGCGCTGCAG
CGCGAAGCGGGGCGGCTGCGCGGCTTCGAGACGGGGACGGTGAACTTTGGCGTCGGCTCTTTCCCTGCCGCGGCCTTCCT
CGGCTCCGTAATGACACGCGTGGCGCGCGACTATCCCGGGCTGGTGGTACGCGTGGAAACCGAGAGCTGGCGTCGGCTGC
TCGAAAAGCTGCAGCGCGACGAGCTCGATTTTGTCGTGGCCGTGACCCACAGCCTGCCGCCGCCGGCGGATTTCCAGGTG
CGGGAGTTGCCAGCGCAGCGCATGGGGTTCTTCGTACGGCCGGGGCATCCGTTGGCGGGGCTCGGTCAGGAGGCGGTGCG
CGGGCAGATTGCCGGTTTTGGGCTTGCCACGACCACGCTGCCGCCACGCGCGCGCAGCGAACTGGCAGCGCTTTTCGGAC
TGCCCAGTGCCGACGAACTGCCGGTACGGCTGGAGTGTGACAACGTGCAGGTGTTGTGCGAGGTGGCCGGCGCGTCTGAC
GCGGTGCTGTTCGCGACCCACGAGGCCGTGCGCAGGGAGTTGGCCGCGGGAACGCTGGCGCCACTGATACTGGAATACCT
CGCTCCGGCGCCTTTACCGCTGACGCTGGTGTACCCCGGTGGACGCAATCTGTCAGGCGCAGCCCAGTTGCTGGTCGGGC
TGCTGGAGGAGTGTGCCGGCTGTCCTGTCACGCCACAAGCGCCTCCGCCGGCCGGCTGA

Upstream 100 bases:

>100_bases
GCGCTCGATGCTCTCTGGCAGGTCTGCGAGCCGAGTATAGGGATTGCCGTACCGTGAAATCCAATGCATATTTGTGGCCT
TCCCTATGAAATAAATCTAT

Downstream 100 bases:

>100_bases
GCGCTACTGGTCCTTCACTTCGACCCGAATCCCTTCCGGCGCCACGGTGATCGCGCCGGGTTCGACGTCCTTGCCGCCGA
AGCGCAGCTCCTCCGGCTTG

Product: regulatory protein LysR

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 312; Mature: 312

Protein sequence:

>312_residues
MLSLRRLEHFAVLAEERSFSRAARRLNLTQPALTRSIQTLEETLELQLVDRAASGLVLTEAGAMVLERSRRMLGDVRALQ
REAGRLRGFETGTVNFGVGSFPAAAFLGSVMTRVARDYPGLVVRVETESWRRLLEKLQRDELDFVVAVTHSLPPPADFQV
RELPAQRMGFFVRPGHPLAGLGQEAVRGQIAGFGLATTTLPPRARSELAALFGLPSADELPVRLECDNVQVLCEVAGASD
AVLFATHEAVRRELAAGTLAPLILEYLAPAPLPLTLVYPGGRNLSGAAQLLVGLLEECAGCPVTPQAPPPAG

Sequences:

>Translated_312_residues
MLSLRRLEHFAVLAEERSFSRAARRLNLTQPALTRSIQTLEETLELQLVDRAASGLVLTEAGAMVLERSRRMLGDVRALQ
REAGRLRGFETGTVNFGVGSFPAAAFLGSVMTRVARDYPGLVVRVETESWRRLLEKLQRDELDFVVAVTHSLPPPADFQV
RELPAQRMGFFVRPGHPLAGLGQEAVRGQIAGFGLATTTLPPRARSELAALFGLPSADELPVRLECDNVQVLCEVAGASD
AVLFATHEAVRRELAAGTLAPLILEYLAPAPLPLTLVYPGGRNLSGAAQLLVGLLEECAGCPVTPQAPPPAG
>Mature_312_residues
MLSLRRLEHFAVLAEERSFSRAARRLNLTQPALTRSIQTLEETLELQLVDRAASGLVLTEAGAMVLERSRRMLGDVRALQ
REAGRLRGFETGTVNFGVGSFPAAAFLGSVMTRVARDYPGLVVRVETESWRRLLEKLQRDELDFVVAVTHSLPPPADFQV
RELPAQRMGFFVRPGHPLAGLGQEAVRGQIAGFGLATTTLPPRARSELAALFGLPSADELPVRLECDNVQVLCEVAGASD
AVLFATHEAVRRELAAGTLAPLILEYLAPAPLPLTLVYPGGRNLSGAAQLLVGLLEECAGCPVTPQAPPPAG

Specific function: Activates the transcription of the sdsA gene for sodium dodecyl sulfate (SDS) degradation [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1787601, Length=179, Percent_Identity=30.7262569832402, Blast_Score=104, Evalue=9e-24,
Organism=Escherichia coli, GI157672245, Length=186, Percent_Identity=30.6451612903226, Blast_Score=80, Evalue=1e-16,
Organism=Escherichia coli, GI145693105, Length=176, Percent_Identity=28.9772727272727, Blast_Score=78, Evalue=7e-16,
Organism=Escherichia coli, GI1789639, Length=127, Percent_Identity=30.7086614173228, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI1787879, Length=182, Percent_Identity=31.3186813186813, Blast_Score=72, Evalue=6e-14,
Organism=Escherichia coli, GI1790399, Length=145, Percent_Identity=26.8965517241379, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI2367136, Length=247, Percent_Identity=28.7449392712551, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1787128, Length=193, Percent_Identity=26.4248704663212, Blast_Score=69, Evalue=4e-13,
Organism=Escherichia coli, GI1788748, Length=146, Percent_Identity=28.0821917808219, Blast_Score=69, Evalue=5e-13,
Organism=Escherichia coli, GI1788297, Length=151, Percent_Identity=29.1390728476821, Blast_Score=66, Evalue=3e-12,
Organism=Escherichia coli, GI87081904, Length=179, Percent_Identity=29.0502793296089, Blast_Score=66, Evalue=3e-12,
Organism=Escherichia coli, GI87082024, Length=176, Percent_Identity=30.1136363636364, Blast_Score=65, Evalue=6e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 33582; Mature: 33582

Theoretical pI: Translated: 6.53; Mature: 6.53

Prosite motif: PS50931 HTH_LYSR ; PS00630 IMP_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLSLRRLEHFAVLAEERSFSRAARRLNLTQPALTRSIQTLEETLELQLVDRAASGLVLTE
CCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEH
AGAMVLERSRRMLGDVRALQREAGRLRGFETGTVNFGVGSFPAAAFLGSVMTRVARDYPG
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEECCCCCHHHHHHHHHHHHHHHHCCCC
LVVRVETESWRRLLEKLQRDELDFVVAVTHSLPPPADFQVRELPAQRMGFFVRPGHPLAG
EEEEEECHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCHHHHCCHHHCCEEECCCCCCCC
LGQEAVRGQIAGFGLATTTLPPRARSELAALFGLPSADELPVRLECDNVQVLCEVAGASD
CCHHHHHHHHHCCCEEECCCCCHHHHHHHHHHCCCCCCCCCEEEECCCEEEEEEECCCCC
AVLFATHEAVRRELAAGTLAPLILEYLAPAPLPLTLVYPGGRNLSGAAQLLVGLLEECAG
EEEEHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCCHHHHHHHHHHHHHCC
CPVTPQAPPPAG
CCCCCCCCCCCC
>Mature Secondary Structure
MLSLRRLEHFAVLAEERSFSRAARRLNLTQPALTRSIQTLEETLELQLVDRAASGLVLTE
CCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEH
AGAMVLERSRRMLGDVRALQREAGRLRGFETGTVNFGVGSFPAAAFLGSVMTRVARDYPG
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEECCCCCHHHHHHHHHHHHHHHHCCCC
LVVRVETESWRRLLEKLQRDELDFVVAVTHSLPPPADFQVRELPAQRMGFFVRPGHPLAG
EEEEEECHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCHHHHCCHHHCCEEECCCCCCCC
LGQEAVRGQIAGFGLATTTLPPRARSELAALFGLPSADELPVRLECDNVQVLCEVAGASD
CCHHHHHHHHHCCCEEECCCCCHHHHHHHHHHCCCCCCCCCEEEECCCEEEEEEECCCCC
AVLFATHEAVRRELAAGTLAPLILEYLAPAPLPLTLVYPGGRNLSGAAQLLVGLLEECAG
EEEEHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCCHHHHHHHHHHHHHCC
CPVTPQAPPPAG
CCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1587481 [H]