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The map label for this gene is mmgC [H]

Identifier: 73539029

GI number: 73539029

Start: 1953909

End: 1955072

Strand: Direct

Name: mmgC [H]

Synonym: Reut_B5206

Alternate gene names: 73539029

Gene position: 1953909-1955072 (Clockwise)

Preceding gene: 73539028

Following gene: 73539030

Centisome position: 71.67

GC content: 66.15

Gene sequence:

>1164_bases
ATGCCCGCAAACATGGTTCTGCAACCGCCCAATCCCCGCTACTACACCGCCGACCACGAAGCATTCCGCGCCTCGGTCCG
CCGCTTCTTCGAGAAGGAAGTCGCCCCGCACGCCGAAGCCTGGGACGAGGCCGGCAGCTTTCCGCGCGAGCTGTACCGCA
AGGCCGCCGAAGCGGGCCTGCTGCAGCCCGGCTTTCCCGAGGCCTACGGCGGCGCGCCTTGCGACGCGTTCTACCGCATG
ATCCTGTTCGAAGAGCGCGCGTGGGGCGGCTCCGGCGGCATCGCGTCGGGGCTGTTCTCGCACACCATCGGCGCGCCGCC
GATTGCCGCGGTCGGCAGCGAAGCGATGAAGGCGCGCGTGTTGCCGCAGATCCTGTCCGGCGAGAAGATTTCCGCGCTCG
CCATCACCGAACCCGGCGCGGGCTCCGATGTCGCGCACCTGACCACATCGGCATGTCGTGAAGGCGACCACTACGTCGTC
AATGGCACCAAGCTCTACATTACGTCGGGCATGCGGGCCGACTACTTCACAGTCGCGGTACGCACCGGTGATCCGGGCGC
CAGTGGCGTGTCATTGCTGCTCATCGAAGGCGATACACCGGGCCTGTCGCGCACGGAACTCAAGAAGATGGGCTGGTGGG
CCTCCGACACCGCGCAGCTCTACTTCGACAACTGCCGAGTACCGGTCGACAACCTGATCGGCGAGGAAGGCAAGGGCTTC
GCCGCGATCACGAAGAACTTCAACCACGAACGCCTGGCCCTGGCGGCCGCAGCCTGCGGCTACGCGCAGGTGTGCTTCCA
CGACGCCCTCGCTTGGGCAGGCGATCGCCACACCTTCGGCAAGCGGCTGGCCGATCACCAGGTAGTGCGCCACCAGCTGG
TCGACATGGCCACGCGCATCGAAGCCACGCGCGCGATGCTGGACGACCTGGCCGCCCGACTGGACGACGGCGCGGCACCG
GTTGCGCAGATCGCCATGGCCAAGAACATGGCCACGCGTACTTTCCAGTTCTGTGCGGATCGCGCGGTGCAGTTGCTTGG
GGGCATGGGTTACATGCGTGGCAGCCGGGTGGAAAGGCTGTACCGGGAAGTGAAGGTCATGATGATCGGTGGGGGAGCGG
AGGAGATCATGAAGGATCTGGCGGCGCGGCAGTTGGGAATTTAG

Upstream 100 bases:

>100_bases
ACGTGGGCCCTGCCCGCGCACCAGCGCTCCGAGCCATTCAACGGCTTCCCGCTCTACGAGCTGCCCGATTGCCTGGCGCC
GGCCGCGGAGTGACCCGACA

Downstream 100 bases:

>100_bases
GCTGTTGTAGCCGGGGTGATCCGCGCAGCGTGGCGTGCCCGCGCACATCGCGTTCCGAGGTTCAGGCGGGCTTAGCAACG
AGGCCTTGTCCGACACATCA

Product: acyl-CoA dehydrogenase

Products: 2,3-dehydroacyl-CoA; reduced acceptor

Alternate protein names: NA

Number of amino acids: Translated: 387; Mature: 386

Protein sequence:

>387_residues
MPANMVLQPPNPRYYTADHEAFRASVRRFFEKEVAPHAEAWDEAGSFPRELYRKAAEAGLLQPGFPEAYGGAPCDAFYRM
ILFEERAWGGSGGIASGLFSHTIGAPPIAAVGSEAMKARVLPQILSGEKISALAITEPGAGSDVAHLTTSACREGDHYVV
NGTKLYITSGMRADYFTVAVRTGDPGASGVSLLLIEGDTPGLSRTELKKMGWWASDTAQLYFDNCRVPVDNLIGEEGKGF
AAITKNFNHERLALAAAACGYAQVCFHDALAWAGDRHTFGKRLADHQVVRHQLVDMATRIEATRAMLDDLAARLDDGAAP
VAQIAMAKNMATRTFQFCADRAVQLLGGMGYMRGSRVERLYREVKVMMIGGGAEEIMKDLAARQLGI

Sequences:

>Translated_387_residues
MPANMVLQPPNPRYYTADHEAFRASVRRFFEKEVAPHAEAWDEAGSFPRELYRKAAEAGLLQPGFPEAYGGAPCDAFYRM
ILFEERAWGGSGGIASGLFSHTIGAPPIAAVGSEAMKARVLPQILSGEKISALAITEPGAGSDVAHLTTSACREGDHYVV
NGTKLYITSGMRADYFTVAVRTGDPGASGVSLLLIEGDTPGLSRTELKKMGWWASDTAQLYFDNCRVPVDNLIGEEGKGF
AAITKNFNHERLALAAAACGYAQVCFHDALAWAGDRHTFGKRLADHQVVRHQLVDMATRIEATRAMLDDLAARLDDGAAP
VAQIAMAKNMATRTFQFCADRAVQLLGGMGYMRGSRVERLYREVKVMMIGGGAEEIMKDLAARQLGI
>Mature_386_residues
PANMVLQPPNPRYYTADHEAFRASVRRFFEKEVAPHAEAWDEAGSFPRELYRKAAEAGLLQPGFPEAYGGAPCDAFYRMI
LFEERAWGGSGGIASGLFSHTIGAPPIAAVGSEAMKARVLPQILSGEKISALAITEPGAGSDVAHLTTSACREGDHYVVN
GTKLYITSGMRADYFTVAVRTGDPGASGVSLLLIEGDTPGLSRTELKKMGWWASDTAQLYFDNCRVPVDNLIGEEGKGFA
AITKNFNHERLALAAAACGYAQVCFHDALAWAGDRHTFGKRLADHQVVRHQLVDMATRIEATRAMLDDLAARLDDGAAPV
AQIAMAKNMATRTFQFCADRAVQLLGGMGYMRGSRVERLYREVKVMMIGGGAEEIMKDLAARQLGI

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI4501857, Length=382, Percent_Identity=37.17277486911, Blast_Score=240, Evalue=1e-63,
Organism=Homo sapiens, GI187960098, Length=376, Percent_Identity=34.3085106382979, Blast_Score=214, Evalue=1e-55,
Organism=Homo sapiens, GI4557231, Length=376, Percent_Identity=34.3085106382979, Blast_Score=214, Evalue=2e-55,
Organism=Homo sapiens, GI7656849, Length=371, Percent_Identity=34.5013477088949, Blast_Score=211, Evalue=8e-55,
Organism=Homo sapiens, GI4501859, Length=375, Percent_Identity=31.7333333333333, Blast_Score=193, Evalue=2e-49,
Organism=Homo sapiens, GI226958412, Length=376, Percent_Identity=29.7872340425532, Blast_Score=191, Evalue=1e-48,
Organism=Homo sapiens, GI4557233, Length=372, Percent_Identity=35.752688172043, Blast_Score=191, Evalue=1e-48,
Organism=Homo sapiens, GI21361497, Length=368, Percent_Identity=31.25, Blast_Score=176, Evalue=5e-44,
Organism=Homo sapiens, GI226958414, Length=341, Percent_Identity=30.4985337243402, Blast_Score=175, Evalue=5e-44,
Organism=Homo sapiens, GI76496475, Length=396, Percent_Identity=30.5555555555556, Blast_Score=161, Evalue=8e-40,
Organism=Homo sapiens, GI4557235, Length=396, Percent_Identity=30.5555555555556, Blast_Score=161, Evalue=8e-40,
Organism=Homo sapiens, GI7669494, Length=342, Percent_Identity=29.2397660818713, Blast_Score=119, Evalue=6e-27,
Organism=Homo sapiens, GI4503943, Length=342, Percent_Identity=29.2397660818713, Blast_Score=118, Evalue=9e-27,
Organism=Homo sapiens, GI38505218, Length=278, Percent_Identity=28.0575539568345, Blast_Score=95, Evalue=1e-19,
Organism=Homo sapiens, GI211971008, Length=288, Percent_Identity=29.5138888888889, Blast_Score=84, Evalue=2e-16,
Organism=Homo sapiens, GI48976061, Length=288, Percent_Identity=29.5138888888889, Blast_Score=84, Evalue=2e-16,
Organism=Escherichia coli, GI87081958, Length=376, Percent_Identity=32.9787234042553, Blast_Score=203, Evalue=1e-53,
Organism=Escherichia coli, GI1786223, Length=362, Percent_Identity=27.9005524861878, Blast_Score=150, Evalue=9e-38,
Organism=Escherichia coli, GI87082384, Length=258, Percent_Identity=29.4573643410853, Blast_Score=78, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17570075, Length=375, Percent_Identity=36.2666666666667, Blast_Score=230, Evalue=1e-60,
Organism=Caenorhabditis elegans, GI17534899, Length=363, Percent_Identity=33.0578512396694, Blast_Score=213, Evalue=2e-55,
Organism=Caenorhabditis elegans, GI17538396, Length=372, Percent_Identity=34.9462365591398, Blast_Score=211, Evalue=6e-55,
Organism=Caenorhabditis elegans, GI17569725, Length=363, Percent_Identity=32.7823691460055, Blast_Score=211, Evalue=7e-55,
Organism=Caenorhabditis elegans, GI17505929, Length=368, Percent_Identity=33.4239130434783, Blast_Score=204, Evalue=4e-53,
Organism=Caenorhabditis elegans, GI17533517, Length=372, Percent_Identity=33.0645161290323, Blast_Score=196, Evalue=1e-50,
Organism=Caenorhabditis elegans, GI17551932, Length=371, Percent_Identity=31.8059299191375, Blast_Score=195, Evalue=3e-50,
Organism=Caenorhabditis elegans, GI17506239, Length=379, Percent_Identity=32.4538258575198, Blast_Score=186, Evalue=2e-47,
Organism=Caenorhabditis elegans, GI17508101, Length=381, Percent_Identity=30.7086614173228, Blast_Score=184, Evalue=7e-47,
Organism=Caenorhabditis elegans, GI71985184, Length=349, Percent_Identity=31.8051575931232, Blast_Score=170, Evalue=1e-42,
Organism=Caenorhabditis elegans, GI71990804, Length=281, Percent_Identity=33.0960854092527, Blast_Score=144, Evalue=8e-35,
Organism=Caenorhabditis elegans, GI71985192, Length=287, Percent_Identity=32.404181184669, Blast_Score=139, Evalue=2e-33,
Organism=Caenorhabditis elegans, GI32563615, Length=227, Percent_Identity=36.1233480176211, Blast_Score=134, Evalue=8e-32,
Organism=Caenorhabditis elegans, GI71982178, Length=284, Percent_Identity=28.5211267605634, Blast_Score=124, Evalue=1e-28,
Organism=Caenorhabditis elegans, GI17534353, Length=341, Percent_Identity=28.7390029325513, Blast_Score=111, Evalue=8e-25,
Organism=Caenorhabditis elegans, GI17531909, Length=240, Percent_Identity=26.6666666666667, Blast_Score=88, Evalue=7e-18,
Organism=Caenorhabditis elegans, GI17562446, Length=287, Percent_Identity=25.7839721254355, Blast_Score=76, Evalue=3e-14,
Organism=Drosophila melanogaster, GI24660351, Length=376, Percent_Identity=34.5744680851064, Blast_Score=211, Evalue=5e-55,
Organism=Drosophila melanogaster, GI24646207, Length=376, Percent_Identity=34.8404255319149, Blast_Score=184, Evalue=6e-47,
Organism=Drosophila melanogaster, GI21356377, Length=365, Percent_Identity=32.3287671232877, Blast_Score=184, Evalue=7e-47,
Organism=Drosophila melanogaster, GI21355753, Length=376, Percent_Identity=31.9148936170213, Blast_Score=183, Evalue=2e-46,
Organism=Drosophila melanogaster, GI24666513, Length=386, Percent_Identity=31.3471502590674, Blast_Score=180, Evalue=2e-45,
Organism=Drosophila melanogaster, GI281363737, Length=288, Percent_Identity=30.5555555555556, Blast_Score=154, Evalue=1e-37,
Organism=Drosophila melanogaster, GI19920834, Length=288, Percent_Identity=27.7777777777778, Blast_Score=96, Evalue=3e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006089
- InterPro:   IPR006092
- InterPro:   IPR006090
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR013786
- InterPro:   IPR009100 [H]

Pfam domain/function: PF00441 Acyl-CoA_dh_1; PF02770 Acyl-CoA_dh_M; PF02771 Acyl-CoA_dh_N [H]

EC number: 1.3.99.3

Molecular weight: Translated: 41880; Mature: 41749

Theoretical pI: Translated: 6.67; Mature: 6.67

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPANMVLQPPNPRYYTADHEAFRASVRRFFEKEVAPHAEAWDEAGSFPRELYRKAAEAGL
CCCCCEEECCCCCEECCCHHHHHHHHHHHHHHHCCCCHHHHHHCCCCHHHHHHHHHHCCC
LQPGFPEAYGGAPCDAFYRMILFEERAWGGSGGIASGLFSHTIGAPPIAAVGSEAMKARV
CCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHCCCCCCHHHHCHHHHHHHH
LPQILSGEKISALAITEPGAGSDVAHLTTSACREGDHYVVNGTKLYITSGMRADYFTVAV
HHHHHCCCCEEEEEEECCCCCCCHHHHHHHHHCCCCEEEECCEEEEEECCCCCCEEEEEE
RTGDPGASGVSLLLIEGDTPGLSRTELKKMGWWASDTAQLYFDNCRVPVDNLIGEEGKGF
ECCCCCCCCEEEEEEECCCCCCCHHHHHHHCCCCCCCHHEEECCCCCCHHHHCCCCCCCE
AAITKNFNHERLALAAAACGYAQVCFHDALAWAGDRHTFGKRLADHQVVRHQLVDMATRI
EEECCCCCHHHHHHHHHHCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHH
EATRAMLDDLAARLDDGAAPVAQIAMAKNMATRTFQFCADRAVQLLGGMGYMRGSRVERL
HHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHH
YREVKVMMIGGGAEEIMKDLAARQLGI
HHHHEEEEECCCHHHHHHHHHHHHCCC
>Mature Secondary Structure 
PANMVLQPPNPRYYTADHEAFRASVRRFFEKEVAPHAEAWDEAGSFPRELYRKAAEAGL
CCCCEEECCCCCEECCCHHHHHHHHHHHHHHHCCCCHHHHHHCCCCHHHHHHHHHHCCC
LQPGFPEAYGGAPCDAFYRMILFEERAWGGSGGIASGLFSHTIGAPPIAAVGSEAMKARV
CCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHCCCCCCHHHHCHHHHHHHH
LPQILSGEKISALAITEPGAGSDVAHLTTSACREGDHYVVNGTKLYITSGMRADYFTVAV
HHHHHCCCCEEEEEEECCCCCCCHHHHHHHHHCCCCEEEECCEEEEEECCCCCCEEEEEE
RTGDPGASGVSLLLIEGDTPGLSRTELKKMGWWASDTAQLYFDNCRVPVDNLIGEEGKGF
ECCCCCCCCEEEEEEECCCCCCCHHHHHHHCCCCCCCHHEEECCCCCCHHHHCCCCCCCE
AAITKNFNHERLALAAAACGYAQVCFHDALAWAGDRHTFGKRLADHQVVRHQLVDMATRI
EEECCCCCHHHHHHHHHHCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHH
EATRAMLDDLAARLDDGAAPVAQIAMAKNMATRTFQFCADRAVQLLGGMGYMRGSRVERL
HHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHH
YREVKVMMIGGGAEEIMKDLAARQLGI
HHHHEEEEECCCHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: acyl-CoA; acceptor

Specific reaction: acyl-CoA + acceptor = 2,3-dehydroacyl-CoA + reduced acceptor

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8759838; 8969508; 9384377 [H]