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The map label for this gene is 73539019

Identifier: 73539019

GI number: 73539019

Start: 1941607

End: 1942911

Strand: Direct

Name: 73539019

Synonym: Reut_B5196

Alternate gene names: NA

Gene position: 1941607-1942911 (Clockwise)

Preceding gene: 73539018

Following gene: 73539020

Centisome position: 71.22

GC content: 63.07

Gene sequence:

>1305_bases
ATGTCTTCTGCGCTCACACCCTTTTTGGCAGTACGGGAAGCCGCTCATCGACTGGACGGCACCTCGTCCGATTATGCGCG
GCTACTTGAGCTGGCGCACGAGAAGCAGTTCGTTCTGCTCGGTGAGGCCACTCACGGCACCGCCGACTTCTACCGAATGC
GTGCACAGATCACGCAGGCGCTGATAGCGGATGAAGGGTTCGATGCCGTTGCCATCGAAGGCGACTGGCCGGACGCGTGG
CGGGTCAATCGCTATGTGCATGGTGAAGGCCACGATGACAGCGTAATGGCTGTTGCCGACTTCCAGAGGTTCCCATCCTG
GATGTGGCGGAACCAGGAGTTCCTGTCATTCATCGAATGGCTGCGCGAACACAACGCCGGCCTGCCTGCGGAGCGGCGTA
CGGGCGTGTACGGCCTTGATCTTTACAGCCTGTATCGCTCCGCAGAGGCCGTGATCCGGTATCTCGCTCCCATCGACCCC
ATGCAGGCGGAGTCGGCCCGGCAGCATTATGCCGCGCTTGATCATGTGCGAGACCCCGCCGCCTATGGTTACCAGGCTGC
GACCGGGGCGCGCATGCCGGCCACGGAGGGCGCCATCCGGCAATTACTTCAGTTGCGCTGCGATGAAGCCGCCTACATCT
CTCGCAATGGCCTCGCTGCTATGGACTCGCACTATTTTGCGGAGCAGAACGCCTTGGTAGTGGTGAATGCCGAGGCCTAC
TACCGCGAGATGTTCGGGCGTCGCGTCAACACCTGGAATCTGCGCGACGCCCATATGGCGCAGACGCTGAACTCGCTGGC
CGAGTACAGGCAGCGGCGCGGCGGAAGCGGCCGTGCCGTGGTCTGGGCACACAATTCACACGTCGGCGATGCCAGCGCGA
CGGAGTCCCGCTTGCGCGGGGAGTGGACTCTCGGCCAACTGGTTCGCAAGCTGGCCGGGACGCGCGCGCTGCTGGTTGGC
TTTACTACTTATACAGGTTATGTGTGCGCGGCATCCGAGTGGGATGGCGATCCCGAGCGAAAGCGCATTGTCCCGGCACT
GCCCGGCAGTTGGGAGTCACTGTTTCACGCCACCGGACTGGACCGCTTCTTTCTTGCGCTGGGCGCCGGCGCAAGCCGGA
CGCTGTCCGAGGCCATGCTCGAGCGGGCGATTGGCGTGCTTTACCTGCCGCAGTCAGAACGGGCCAGCCACTATTTCGAT
GCATCCATCGCCGGCCAGTTCGACGCGCTGTTCCACCTGGATGAAACCGACGCGCTCGAACCCCTTCCCACGCCGCACAA
CGTGGGATCCTCATCGGTGCCTTGA

Upstream 100 bases:

>100_bases
AGGTCGTCGATCGACCAACGCTGGATACGCTGCTCAAGCGCATGCCCGCGCACGAATCGCGCGCCGAGGCCGCCTGACAG
CAAGCCCTGTATGGAACCCT

Downstream 100 bases:

>100_bases
GCTTCAGTGCGAAAACAGCACCGGAACCGTCATCGACGGGAGCAACGCGCGCGTGACTCCGGGGCGTCCATACATTTAAA
AGCTCACTGATGTTCAGAAA

Product: erythromycin esterase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 434; Mature: 433

Protein sequence:

>434_residues
MSSALTPFLAVREAAHRLDGTSSDYARLLELAHEKQFVLLGEATHGTADFYRMRAQITQALIADEGFDAVAIEGDWPDAW
RVNRYVHGEGHDDSVMAVADFQRFPSWMWRNQEFLSFIEWLREHNAGLPAERRTGVYGLDLYSLYRSAEAVIRYLAPIDP
MQAESARQHYAALDHVRDPAAYGYQAATGARMPATEGAIRQLLQLRCDEAAYISRNGLAAMDSHYFAEQNALVVVNAEAY
YREMFGRRVNTWNLRDAHMAQTLNSLAEYRQRRGGSGRAVVWAHNSHVGDASATESRLRGEWTLGQLVRKLAGTRALLVG
FTTYTGYVCAASEWDGDPERKRIVPALPGSWESLFHATGLDRFFLALGAGASRTLSEAMLERAIGVLYLPQSERASHYFD
ASIAGQFDALFHLDETDALEPLPTPHNVGSSSVP

Sequences:

>Translated_434_residues
MSSALTPFLAVREAAHRLDGTSSDYARLLELAHEKQFVLLGEATHGTADFYRMRAQITQALIADEGFDAVAIEGDWPDAW
RVNRYVHGEGHDDSVMAVADFQRFPSWMWRNQEFLSFIEWLREHNAGLPAERRTGVYGLDLYSLYRSAEAVIRYLAPIDP
MQAESARQHYAALDHVRDPAAYGYQAATGARMPATEGAIRQLLQLRCDEAAYISRNGLAAMDSHYFAEQNALVVVNAEAY
YREMFGRRVNTWNLRDAHMAQTLNSLAEYRQRRGGSGRAVVWAHNSHVGDASATESRLRGEWTLGQLVRKLAGTRALLVG
FTTYTGYVCAASEWDGDPERKRIVPALPGSWESLFHATGLDRFFLALGAGASRTLSEAMLERAIGVLYLPQSERASHYFD
ASIAGQFDALFHLDETDALEPLPTPHNVGSSSVP
>Mature_433_residues
SSALTPFLAVREAAHRLDGTSSDYARLLELAHEKQFVLLGEATHGTADFYRMRAQITQALIADEGFDAVAIEGDWPDAWR
VNRYVHGEGHDDSVMAVADFQRFPSWMWRNQEFLSFIEWLREHNAGLPAERRTGVYGLDLYSLYRSAEAVIRYLAPIDPM
QAESARQHYAALDHVRDPAAYGYQAATGARMPATEGAIRQLLQLRCDEAAYISRNGLAAMDSHYFAEQNALVVVNAEAYY
REMFGRRVNTWNLRDAHMAQTLNSLAEYRQRRGGSGRAVVWAHNSHVGDASATESRLRGEWTLGQLVRKLAGTRALLVGF
TTYTGYVCAASEWDGDPERKRIVPALPGSWESLFHATGLDRFFLALGAGASRTLSEAMLERAIGVLYLPQSERASHYFDA
SIAGQFDALFHLDETDALEPLPTPHNVGSSSVP

Specific function: Unknown

COG id: COG2312

COG function: function code R; Erythromycin esterase homolog

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: In the N-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007815
- InterPro:   IPR000836 [H]

Pfam domain/function: PF05139 Erythro_esteras; PF00156 Pribosyltran [H]

EC number: NA

Molecular weight: Translated: 48363; Mature: 48231

Theoretical pI: Translated: 5.96; Mature: 5.96

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSALTPFLAVREAAHRLDGTSSDYARLLELAHEKQFVLLGEATHGTADFYRMRAQITQA
CCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHHHH
LIADEGFDAVAIEGDWPDAWRVNRYVHGEGHDDSVMAVADFQRFPSWMWRNQEFLSFIEW
HHHCCCCCEEEEECCCCCCCEECEEEECCCCCCCEEEHHHHHHHHHHHHCCHHHHHHHHH
LREHNAGLPAERRTGVYGLDLYSLYRSAEAVIRYLAPIDPMQAESARQHYAALDHVRDPA
HHHCCCCCCCHHCCCEEEHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCH
AYGYQAATGARMPATEGAIRQLLQLRCDEAAYISRNGLAAMDSHYFAEQNALVVVNAEAY
HCCCCCCCCCCCCCCHHHHHHHHHHHCCCHHHCCCCCCHHHHHHHHHCCCCEEEEECHHH
YREMFGRRVNTWNLRDAHMAQTLNSLAEYRQRRGGSGRAVVWAHNSHVGDASATESRLRG
HHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCHHHHHHHCC
EWTLGQLVRKLAGTRALLVGFTTYTGYVCAASEWDGDPERKRIVPALPGSWESLFHATGL
CCCHHHHHHHHHCCEEEEEEEHHHCCEEEECCCCCCCHHHCEECCCCCCCHHHHHHHCCH
DRFFLALGAGASRTLSEAMLERAIGVLYLPQSERASHYFDASIAGQFDALFHLDETDALE
HHHHHHHCCCCHHHHHHHHHHHHHCEEECCCCCCCCHHCCCHHCCCCHHEEECCCCCCCC
PLPTPHNVGSSSVP
CCCCCCCCCCCCCC
>Mature Secondary Structure 
SSALTPFLAVREAAHRLDGTSSDYARLLELAHEKQFVLLGEATHGTADFYRMRAQITQA
CCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHHHH
LIADEGFDAVAIEGDWPDAWRVNRYVHGEGHDDSVMAVADFQRFPSWMWRNQEFLSFIEW
HHHCCCCCEEEEECCCCCCCEECEEEECCCCCCCEEEHHHHHHHHHHHHCCHHHHHHHHH
LREHNAGLPAERRTGVYGLDLYSLYRSAEAVIRYLAPIDPMQAESARQHYAALDHVRDPA
HHHCCCCCCCHHCCCEEEHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCH
AYGYQAATGARMPATEGAIRQLLQLRCDEAAYISRNGLAAMDSHYFAEQNALVVVNAEAY
HCCCCCCCCCCCCCCHHHHHHHHHHHCCCHHHCCCCCCHHHHHHHHHCCCCEEEEECHHH
YREMFGRRVNTWNLRDAHMAQTLNSLAEYRQRRGGSGRAVVWAHNSHVGDASATESRLRG
HHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCHHHHHHHCC
EWTLGQLVRKLAGTRALLVGFTTYTGYVCAASEWDGDPERKRIVPALPGSWESLFHATGL
CCCHHHHHHHHHCCEEEEEEEHHHCCEEEECCCCCCCHHHCEECCCCCCCHHHHHHHCCH
DRFFLALGAGASRTLSEAMLERAIGVLYLPQSERASHYFDASIAGQFDALFHLDETDALE
HHHHHHHCCCCHHHHHHHHHHHHHCEEECCCCCCCCHHCCCHHCCCCHHEEECCCCCCCC
PLPTPHNVGSSSVP
CCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]