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The map label for this gene is ligD

Identifier: 73538904

GI number: 73538904

Start: 1817933

End: 1820638

Strand: Direct

Name: ligD

Synonym: Reut_B5079

Alternate gene names: NA

Gene position: 1817933-1820638 (Clockwise)

Preceding gene: 73538902

Following gene: 73538905

Centisome position: 66.68

GC content: 67.89

Gene sequence:

>2706_bases
ATGGCCAAGACCACGCGCCAGACCCCTGACGACACCCGCGGCACGCGTAGCACCCGAACTGCGGAGCCCGCGCGCAAGCG
CCCGGCCGACGCGCTCGGCAAGTATCGCCAGATGCGGGATTTCGCAGCCACGCCCGAACCCGGCGGCACGCGCCAGCGCG
CCAGGGCAACGCCAAAGGCAAAGCGCGCCGGCACCTTGTCCTTCGTCATCCAGAAGCACGCTGCGCGGCGGTTGCATTAT
GACTTCCGGCTGGAACTCGACGGCACGCTGAAAAGCTGGGCCGTGCCAAAGGGTCCGAGCCTGGACCCCGCCGACAAGCG
CATGGCGGTGCATGTGGAAGACCATCCGCTCGACTATGCGGGCTTCGAGGGCGTGATCCCGCCGGGCCACTACGGCGCTG
GCACGGTGATCGTGTGGGATCGTGGGATCTGGGTGCCCGACGGCGATGCCGATGCGGCCTATCGCGCCGGCAAGCTCAAG
TTCGAGTTGCGCGGCGAAAAGCTGCATGGCCACTGGACGCTGGTGCGCATGCACGGCAGCCGGCAGAAGGAGCAGGATGC
CTGGCTGCTGATCAAGGAGCGCGACGATGCGGCGGTGCCCGCATCCGAATTCGACGTGACCGAAGCGCTGCCCGACAGCG
TGCTGGCCGGCACATCGGCCGCGCGCAAGACCACCGGGCGAAGGGCCGCTACGAACGCTACGAAGCCCGGCAACGGCGCC
AAGGACAGCACCAAGGACAGCGCCAGAACCAAGCCCTTGCCGCTCCCACGTCGCGCCACTGCCGCAGCACTGCCGCTCGC
GCTGTCGCCGCAACTGGCCACGCTGGTCGAGCGAGCGCCCCCCGATGCCGATGCATGGCGCTACGAGATCAAGTTCGACG
GCTACCGCATGCTGGCCCGTATCGACGGCGACGACGTGCGCTTGTTTACGCGCCAGGGCCACGACTGGACATCGCGCCTC
AAGACGCTCGCGCGCGAAGTGCGCGCGCTCGGATTGCCCGATGGCTGGCTCGATGGGGAAATCGTCGTGCTCGGCAAGCA
CGGCGAGACCGATTTCCAGGCCTTGCAGAATGCCTTCGAGACGTCGCACGTGGAATCGATCCAGTACTTCGTCTTCGACC
TGCCGTTCTATGCCGGCCACGACCTGCGCAAGGCGCCGCTGTCCGAACGGCGCGCGCTGCTGCGGCGCCTGTTCGAGAAC
AACACCGGCACACGCCTGCGCTTCAGCGAGGAATTCGAAGCCGCCCCCGACGAAATGCTCGACGCTGCCTGTCGCATGAA
GCTCGAAGGCGTGATCGGCAAGCGCATCGACGCGCCGTATGTCAGCACGCGCAGCAACACGTGGATCAAGCTCAAATGCA
CGCAGCGCCAGGAGTTCGTGATCGGCGGCTTTACCGAGCCCAAGGGCAGCCGCCAGGGTCTCGGCTCCCTGCTGCTCGGC
GTGCACGACAGCGCCGGGCGCCTGCGTTATGCGGGCAATGTGGGAACGGGGTTCGATACGCGCTCGCTGGCCAGCCTGCG
CGAACAGCTGGATGCGCAGCGCACGGACAAGGCGCCCTTCCATGAGCTGCCCTCCTCGATCAAGGGGCTGTGGGTTCGGC
CGCGGCTCGTGGCCGAGGTGTCGTTCGGATCGTGGACGCGCGAAGGCCGCGTGCGCCATGCCGTGTTCCATGGCTTGCGC
AGCGATAAACCCGCCAGCGCGGTGTCCGTGGAAAAGCCCGCCGCACCCGCCGGCCGCAAGACGGCGGCCACAACCGCAGC
CAGGAGCGCGCCAGCCACCACACGCAAGGGCAAACCCACGGCGGCGAACGGCAAGGTCGCCATCAGTCACTCGGAGCGCG
TCATCGATACCGCCAGCGGGCTGACCAAGGGAGACCTGGTGCGCTACTACGAAAGCGCGGCGCCACTGATGCTGCCGCAT
CTGCGCGGCCGCCCCATCGCCATGGTGCGGGCGCCGGCCGGCGTCGCCGGCCAGCAGTTTTTCCAGCGGCATGGCGACAC
GCTAAAGATCGACGGCGTCAACGTGCTCGATCCGGACCTGTGGCCGGGTCATCCGGCGCTGCTCGAGATCGTCTCGGAGC
ACGCACTGGTGGCCGCGGCGCAGCTTAATGTGGTGGAGTTCCATACCTGGAATGCCAACAAGCGCAGCATGGACCGGCCC
AACCGCATCATCTTCGATCTCGACCCCGGGGAGGGCGTGCCGTGGCCGCACATGCGCGAAGCCGCGGCGCTGATGAAGGC
GTGGCTTGACGAACTCGGGCTCGCCAGTTTCCTGAAGACCAGCGGCGGCAAGGGCCTGCACGTGGTGGTGCCGCTGACAC
CGCGCGCGGGCTGGGATGAGGTCAAGGAGTTTGCCCACGGTGTGGTGCTGCACATGGCCGTGACGATTCCGCAGCGCTTC
GTGGCCAAGAGCGGCGCGGGCAACCGCATTGGCAAGATTTTCATCGATTACCTGCGCAATGGCGTTGGCGCCACGACGGC
CGCGGCATTCTCCGCGCGGGCGCGCCCCGGCCTGGGCGTGTCGGTTCCGCTTGCGTGGGACGAGCTCGACGGGCTCGAGG
CCTCCGACCAGTGGACCGTCGCCAATGTGGCGCCTCGCCTGGACGAGCTGGCACGCCACGACCCCTGGGACACTTATGCG
GACACCCGCCAGACCATCACGCGCGCTGCCACCAGGCTGGCTCGCGCCGGAAGGAGCAAGCCATGA

Upstream 100 bases:

>100_bases
CGACTCAGGTGTAGGACTGGCGCCGATTTCGGCGCGCCAGGGCCGTGCCTAAGCTGAAGCCACCGAGGTTCGCCTCCTTG
CAAGGTGAGGCTGGTTCACC

Downstream 100 bases:

>100_bases
CCCGATCCTTGATTCCCTATCTCCGCCATGTGCGCCTGGCTGGCGCCGCCGGGCCGCACTTTTCCCGGCGCGCGCTGGCC
GCCGCGTTGCTGATCGCCGT

Product: ATP-dependent DNA ligase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 901; Mature: 900

Protein sequence:

>901_residues
MAKTTRQTPDDTRGTRSTRTAEPARKRPADALGKYRQMRDFAATPEPGGTRQRARATPKAKRAGTLSFVIQKHAARRLHY
DFRLELDGTLKSWAVPKGPSLDPADKRMAVHVEDHPLDYAGFEGVIPPGHYGAGTVIVWDRGIWVPDGDADAAYRAGKLK
FELRGEKLHGHWTLVRMHGSRQKEQDAWLLIKERDDAAVPASEFDVTEALPDSVLAGTSAARKTTGRRAATNATKPGNGA
KDSTKDSARTKPLPLPRRATAAALPLALSPQLATLVERAPPDADAWRYEIKFDGYRMLARIDGDDVRLFTRQGHDWTSRL
KTLAREVRALGLPDGWLDGEIVVLGKHGETDFQALQNAFETSHVESIQYFVFDLPFYAGHDLRKAPLSERRALLRRLFEN
NTGTRLRFSEEFEAAPDEMLDAACRMKLEGVIGKRIDAPYVSTRSNTWIKLKCTQRQEFVIGGFTEPKGSRQGLGSLLLG
VHDSAGRLRYAGNVGTGFDTRSLASLREQLDAQRTDKAPFHELPSSIKGLWVRPRLVAEVSFGSWTREGRVRHAVFHGLR
SDKPASAVSVEKPAAPAGRKTAATTAARSAPATTRKGKPTAANGKVAISHSERVIDTASGLTKGDLVRYYESAAPLMLPH
LRGRPIAMVRAPAGVAGQQFFQRHGDTLKIDGVNVLDPDLWPGHPALLEIVSEHALVAAAQLNVVEFHTWNANKRSMDRP
NRIIFDLDPGEGVPWPHMREAAALMKAWLDELGLASFLKTSGGKGLHVVVPLTPRAGWDEVKEFAHGVVLHMAVTIPQRF
VAKSGAGNRIGKIFIDYLRNGVGATTAAAFSARARPGLGVSVPLAWDELDGLEASDQWTVANVAPRLDELARHDPWDTYA
DTRQTITRAATRLARAGRSKP

Sequences:

>Translated_901_residues
MAKTTRQTPDDTRGTRSTRTAEPARKRPADALGKYRQMRDFAATPEPGGTRQRARATPKAKRAGTLSFVIQKHAARRLHY
DFRLELDGTLKSWAVPKGPSLDPADKRMAVHVEDHPLDYAGFEGVIPPGHYGAGTVIVWDRGIWVPDGDADAAYRAGKLK
FELRGEKLHGHWTLVRMHGSRQKEQDAWLLIKERDDAAVPASEFDVTEALPDSVLAGTSAARKTTGRRAATNATKPGNGA
KDSTKDSARTKPLPLPRRATAAALPLALSPQLATLVERAPPDADAWRYEIKFDGYRMLARIDGDDVRLFTRQGHDWTSRL
KTLAREVRALGLPDGWLDGEIVVLGKHGETDFQALQNAFETSHVESIQYFVFDLPFYAGHDLRKAPLSERRALLRRLFEN
NTGTRLRFSEEFEAAPDEMLDAACRMKLEGVIGKRIDAPYVSTRSNTWIKLKCTQRQEFVIGGFTEPKGSRQGLGSLLLG
VHDSAGRLRYAGNVGTGFDTRSLASLREQLDAQRTDKAPFHELPSSIKGLWVRPRLVAEVSFGSWTREGRVRHAVFHGLR
SDKPASAVSVEKPAAPAGRKTAATTAARSAPATTRKGKPTAANGKVAISHSERVIDTASGLTKGDLVRYYESAAPLMLPH
LRGRPIAMVRAPAGVAGQQFFQRHGDTLKIDGVNVLDPDLWPGHPALLEIVSEHALVAAAQLNVVEFHTWNANKRSMDRP
NRIIFDLDPGEGVPWPHMREAAALMKAWLDELGLASFLKTSGGKGLHVVVPLTPRAGWDEVKEFAHGVVLHMAVTIPQRF
VAKSGAGNRIGKIFIDYLRNGVGATTAAAFSARARPGLGVSVPLAWDELDGLEASDQWTVANVAPRLDELARHDPWDTYA
DTRQTITRAATRLARAGRSKP
>Mature_900_residues
AKTTRQTPDDTRGTRSTRTAEPARKRPADALGKYRQMRDFAATPEPGGTRQRARATPKAKRAGTLSFVIQKHAARRLHYD
FRLELDGTLKSWAVPKGPSLDPADKRMAVHVEDHPLDYAGFEGVIPPGHYGAGTVIVWDRGIWVPDGDADAAYRAGKLKF
ELRGEKLHGHWTLVRMHGSRQKEQDAWLLIKERDDAAVPASEFDVTEALPDSVLAGTSAARKTTGRRAATNATKPGNGAK
DSTKDSARTKPLPLPRRATAAALPLALSPQLATLVERAPPDADAWRYEIKFDGYRMLARIDGDDVRLFTRQGHDWTSRLK
TLAREVRALGLPDGWLDGEIVVLGKHGETDFQALQNAFETSHVESIQYFVFDLPFYAGHDLRKAPLSERRALLRRLFENN
TGTRLRFSEEFEAAPDEMLDAACRMKLEGVIGKRIDAPYVSTRSNTWIKLKCTQRQEFVIGGFTEPKGSRQGLGSLLLGV
HDSAGRLRYAGNVGTGFDTRSLASLREQLDAQRTDKAPFHELPSSIKGLWVRPRLVAEVSFGSWTREGRVRHAVFHGLRS
DKPASAVSVEKPAAPAGRKTAATTAARSAPATTRKGKPTAANGKVAISHSERVIDTASGLTKGDLVRYYESAAPLMLPHL
RGRPIAMVRAPAGVAGQQFFQRHGDTLKIDGVNVLDPDLWPGHPALLEIVSEHALVAAAQLNVVEFHTWNANKRSMDRPN
RIIFDLDPGEGVPWPHMREAAALMKAWLDELGLASFLKTSGGKGLHVVVPLTPRAGWDEVKEFAHGVVLHMAVTIPQRFV
AKSGAGNRIGKIFIDYLRNGVGATTAAAFSARARPGLGVSVPLAWDELDGLEASDQWTVANVAPRLDELARHDPWDTYAD
TRQTITRAATRLARAGRSKP

Specific function: Unknown

COG id: COG1793

COG function: function code L; ATP-dependent DNA ligase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATP-dependent DNA ligase family [H]

Homologues:

Organism=Homo sapiens, GI4557719, Length=255, Percent_Identity=27.843137254902, Blast_Score=73, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI71985269, Length=302, Percent_Identity=28.1456953642384, Blast_Score=80, Evalue=3e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012309
- InterPro:   IPR012310
- InterPro:   IPR014146
- InterPro:   IPR002755
- InterPro:   IPR014144
- InterPro:   IPR014145
- InterPro:   IPR012340
- InterPro:   IPR016027 [H]

Pfam domain/function: PF04679 DNA_ligase_A_C; PF01068 DNA_ligase_A_M; PF01896 DNA_primase_S [H]

EC number: NA

Molecular weight: Translated: 98872; Mature: 98741

Theoretical pI: Translated: 10.41; Mature: 10.41

Prosite motif: PS50160 DNA_LIGASE_A3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKTTRQTPDDTRGTRSTRTAEPARKRPADALGKYRQMRDFAATPEPGGTRQRARATPKA
CCCCCCCCCCCCCCCCCCCCCCHHHCCCHHHHHHHHHHHHHCCCCCCCCCHHHHHCCCCH
KRAGTLSFVIQKHAARRLHYDFRLELDGTLKSWAVPKGPSLDPADKRMAVHVEDHPLDYA
HHCCHHHHHHHHHHHHHCCEEEEEEECCCHHHCCCCCCCCCCCCCCEEEEEEECCCCCCC
GFEGVIPPGHYGAGTVIVWDRGIWVPDGDADAAYRAGKLKFELRGEKLHGHWTLVRMHGS
CCCCCCCCCCCCCCEEEEEECCEECCCCCCCHHHHCCCEEEEEECCEECCEEEEEEECCC
RQKEQDAWLLIKERDDAAVPASEFDVTEALPDSVLAGTSAARKTTGRRAATNATKPGNGA
CCCCCCCEEEEECCCCCCCCCCCCCHHHHCCHHHHHCCCHHHHHCCCHHCCCCCCCCCCC
KDSTKDSARTKPLPLPRRATAAALPLALSPQLATLVERAPPDADAWRYEIKFDGYRMLAR
CCCCCCCCCCCCCCCCCCHHHHHCCEECCHHHHHHHHHCCCCCCCEEEEEEECCEEEEEE
IDGDDVRLFTRQGHDWTSRLKTLAREVRALGLPDGWLDGEIVVLGKHGETDFQALQNAFE
ECCCCEEEEEECCCCHHHHHHHHHHHHHHCCCCCCCCCCEEEEEECCCCHHHHHHHHHHH
TSHVESIQYFVFDLPFYAGHDLRKAPLSERRALLRRLFENNTGTRLRFSEEFEAAPDEML
HHHHHHEEEEEEECCHHCCCCHHCCCHHHHHHHHHHHHHCCCCCEEEECHHHCCCHHHHH
DAACRMKLEGVIGKRIDAPYVSTRSNTWIKLKCTQRQEFVIGGFTEPKGSRQGLGSLLLG
HHHHHHHHHHHHHCCCCCCCEECCCCCEEEEEECCCCEEEEECCCCCCCCHHHHHHHHEE
VHDSAGRLRYAGNVGTGFDTRSLASLREQLDAQRTDKAPFHELPSSIKGLWVRPRLVAEV
EECCCCCEEEECCCCCCCCHHHHHHHHHHHHHHCCCCCCHHHCCHHHCCEEECCEEEEEE
SFGSWTREGRVRHAVFHGLRSDKPASAVSVEKPAAPAGRKTAATTAARSAPATTRKGKPT
CCCCCCCCCCHHHHHHHHHCCCCCCCCEECCCCCCCCCCCHHHHHHHCCCCCCCCCCCCC
AANGKVAISHSERVIDTASGLTKGDLVRYYESAAPLMLPHLRGRPIAMVRAPAGVAGQQF
CCCCEEEEECCCHHHHHHCCCCHHHHHHHHHHCCCEECCCCCCCCEEEEECCCCCHHHHH
FQRHGDTLKIDGVNVLDPDLWPGHPALLEIVSEHALVAAAQLNVVEFHTWNANKRSMDRP
HHHCCCEEEECCCCEECCCCCCCCHHHHHHHHHHHHEEEEEEEEEEEEECCCCCCCCCCC
NRIIFDLDPGEGVPWPHMREAAALMKAWLDELGLASFLKTSGGKGLHVVVPLTPRAGWDE
CEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCHHH
VKEFAHGVVLHMAVTIPQRFVAKSGAGNRIGKIFIDYLRNGVGATTAAAFSARARPGLGV
HHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCHHHHHHHHCCCCCCCCE
SVPLAWDELDGLEASDQWTVANVAPRLDELARHDPWDTYADTRQTITRAATRLARAGRSK
EEEECHHHCCCCCCCCCEEEHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCC
P
C
>Mature Secondary Structure 
AKTTRQTPDDTRGTRSTRTAEPARKRPADALGKYRQMRDFAATPEPGGTRQRARATPKA
CCCCCCCCCCCCCCCCCCCCCHHHCCCHHHHHHHHHHHHHCCCCCCCCCHHHHHCCCCH
KRAGTLSFVIQKHAARRLHYDFRLELDGTLKSWAVPKGPSLDPADKRMAVHVEDHPLDYA
HHCCHHHHHHHHHHHHHCCEEEEEEECCCHHHCCCCCCCCCCCCCCEEEEEEECCCCCCC
GFEGVIPPGHYGAGTVIVWDRGIWVPDGDADAAYRAGKLKFELRGEKLHGHWTLVRMHGS
CCCCCCCCCCCCCCEEEEEECCEECCCCCCCHHHHCCCEEEEEECCEECCEEEEEEECCC
RQKEQDAWLLIKERDDAAVPASEFDVTEALPDSVLAGTSAARKTTGRRAATNATKPGNGA
CCCCCCCEEEEECCCCCCCCCCCCCHHHHCCHHHHHCCCHHHHHCCCHHCCCCCCCCCCC
KDSTKDSARTKPLPLPRRATAAALPLALSPQLATLVERAPPDADAWRYEIKFDGYRMLAR
CCCCCCCCCCCCCCCCCCHHHHHCCEECCHHHHHHHHHCCCCCCCEEEEEEECCEEEEEE
IDGDDVRLFTRQGHDWTSRLKTLAREVRALGLPDGWLDGEIVVLGKHGETDFQALQNAFE
ECCCCEEEEEECCCCHHHHHHHHHHHHHHCCCCCCCCCCEEEEEECCCCHHHHHHHHHHH
TSHVESIQYFVFDLPFYAGHDLRKAPLSERRALLRRLFENNTGTRLRFSEEFEAAPDEML
HHHHHHEEEEEEECCHHCCCCHHCCCHHHHHHHHHHHHHCCCCCEEEECHHHCCCHHHHH
DAACRMKLEGVIGKRIDAPYVSTRSNTWIKLKCTQRQEFVIGGFTEPKGSRQGLGSLLLG
HHHHHHHHHHHHHCCCCCCCEECCCCCEEEEEECCCCEEEEECCCCCCCCHHHHHHHHEE
VHDSAGRLRYAGNVGTGFDTRSLASLREQLDAQRTDKAPFHELPSSIKGLWVRPRLVAEV
EECCCCCEEEECCCCCCCCHHHHHHHHHHHHHHCCCCCCHHHCCHHHCCEEECCEEEEEE
SFGSWTREGRVRHAVFHGLRSDKPASAVSVEKPAAPAGRKTAATTAARSAPATTRKGKPT
CCCCCCCCCCHHHHHHHHHCCCCCCCCEECCCCCCCCCCCHHHHHHHCCCCCCCCCCCCC
AANGKVAISHSERVIDTASGLTKGDLVRYYESAAPLMLPHLRGRPIAMVRAPAGVAGQQF
CCCCEEEEECCCHHHHHHCCCCHHHHHHHHHHCCCEECCCCCCCCEEEEECCCCCHHHHH
FQRHGDTLKIDGVNVLDPDLWPGHPALLEIVSEHALVAAAQLNVVEFHTWNANKRSMDRP
HHHCCCEEEECCCCEECCCCCCCCHHHHHHHHHHHHEEEEEEEEEEEEECCCCCCCCCCC
NRIIFDLDPGEGVPWPHMREAAALMKAWLDELGLASFLKTSGGKGLHVVVPLTPRAGWDE
CEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCHHH
VKEFAHGVVLHMAVTIPQRFVAKSGAGNRIGKIFIDYLRNGVGATTAAAFSARARPGLGV
HHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCHHHHHHHHCCCCCCCCE
SVPLAWDELDGLEASDQWTVANVAPRLDELARHDPWDTYADTRQTITRAATRLARAGRSK
EEEECHHHCCCCCCCCCEEEHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCC
P
C

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]