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The map label for this gene is virS [H]

Identifier: 73538874

GI number: 73538874

Start: 1786348

End: 1787403

Strand: Reverse

Name: virS [H]

Synonym: Reut_B5049

Alternate gene names: 73538874

Gene position: 1787403-1786348 (Counterclockwise)

Preceding gene: 73538875

Following gene: 73538871

Centisome position: 65.57

GC content: 63.92

Gene sequence:

>1056_bases
GTGCAGACGGCCAGCGTCGGCAAGCTGATCCGCAGCGCCAGCCTGAACGGTTACATCGAACTGGTGGAGTCGCTCGGGCT
GGACCCCTACGCGTTCCTGCGCGGAGTCGGATTGTCGGCGCGGCTGCTGGAAGACCCGGAACGGCTGATCCCGAGCCATG
CCGTTCGCGAACTGCTCGAAGTCACGGCAGCTGCCACCGGCGTGGAAGATTTCGCGCTGCGGCTCGCGGCCCAGCGCTCG
TTCTCGAACCTCGGGCCGATCAGCCTGGTGCTGAAGGAAGAGCCCACGCCGCGGCTGGCGCTCGAGACGCTGTGCCGCTA
TCTCAAGCTGCTCAGCGCGTCGCTGATCACGCGTATCGAGGACAGCGGCAACACCGTGATCGTCCGCGAGGAACTCGTGC
CGAGTCCAGGGCTTGCCACGCGGCAGGCCATGGAGCTCGCCGTGGGTGTGAAGTTTCGCATCCTGCGCGAACTGATCGGT
CCGCGGTGGCGGCCCGTCGAGGTGTGCTTCACGCATCGCGCGCCGCTCGATGTATCGGCGCACCGTGTCTTCTTCGGTTG
CAAGCCGATTTTCAACCAGTCGTTCAATGGGCTGGTCTGCGCGGCGGCGGACTTGCAGATGCCACGAACGACGGAGAATG
CGGGCGCGGCACGCTTTGCGCGCGACTACCTTGAGACGGCGCTTCGGCAGCGTAGTGAAGGCATTCGTGAATCGTGCCGG
GAGTTGATCCTGGCTTTGCTGCCGGGTGGGCGCTGTACTGCGCAGCAACTGGCGCACCATCTGCGTGTCGACCGTCGCAC
GCTTTACCGGTATCTCAATGCGGAAGGGGTGACGTTTTCAGAGTTGCTCAATGAGGTGCGGGCGGAGTTGGTGATACGCC
ATCTTCGGGAAAGTGACCTGCCAGTGGGCGAGGTTTCAGCCTTGCTCGGATTCTCGGCGCAAAGCTGCTTCAGTCACTGG
TTTCGCGTGACGTTTGGGTGTAGTGCGTCTGAGTGGCGCAGGCAAACGATGTTCGCCGGTCCGCAAGCTCGCGCCGAAGC
GGTGCTGGAGCGATAA

Upstream 100 bases:

>100_bases
GTTCGGCGGCTACCACGGAGGAGCTGGCCAGGGACGTGCGGGAGTCGTACGAACGCCAGGGCAAGCTGCTGCGCTCGATC
GACTTCAAGCCGGAGTGATC

Downstream 100 bases:

>100_bases
GTGTGGCGCATCTGATCTGAAAGCGAAGCAAGAAGCATATCCAGCTGAGCCATCGCGCGTCAGCAACAACGTCTGGAACC
GTGGGTCAAGCGCCGGCAGC

Product: AraC family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 351; Mature: 351

Protein sequence:

>351_residues
MQTASVGKLIRSASLNGYIELVESLGLDPYAFLRGVGLSARLLEDPERLIPSHAVRELLEVTAAATGVEDFALRLAAQRS
FSNLGPISLVLKEEPTPRLALETLCRYLKLLSASLITRIEDSGNTVIVREELVPSPGLATRQAMELAVGVKFRILRELIG
PRWRPVEVCFTHRAPLDVSAHRVFFGCKPIFNQSFNGLVCAAADLQMPRTTENAGAARFARDYLETALRQRSEGIRESCR
ELILALLPGGRCTAQQLAHHLRVDRRTLYRYLNAEGVTFSELLNEVRAELVIRHLRESDLPVGEVSALLGFSAQSCFSHW
FRVTFGCSASEWRRQTMFAGPQARAEAVLER

Sequences:

>Translated_351_residues
MQTASVGKLIRSASLNGYIELVESLGLDPYAFLRGVGLSARLLEDPERLIPSHAVRELLEVTAAATGVEDFALRLAAQRS
FSNLGPISLVLKEEPTPRLALETLCRYLKLLSASLITRIEDSGNTVIVREELVPSPGLATRQAMELAVGVKFRILRELIG
PRWRPVEVCFTHRAPLDVSAHRVFFGCKPIFNQSFNGLVCAAADLQMPRTTENAGAARFARDYLETALRQRSEGIRESCR
ELILALLPGGRCTAQQLAHHLRVDRRTLYRYLNAEGVTFSELLNEVRAELVIRHLRESDLPVGEVSALLGFSAQSCFSHW
FRVTFGCSASEWRRQTMFAGPQARAEAVLER
>Mature_351_residues
MQTASVGKLIRSASLNGYIELVESLGLDPYAFLRGVGLSARLLEDPERLIPSHAVRELLEVTAAATGVEDFALRLAAQRS
FSNLGPISLVLKEEPTPRLALETLCRYLKLLSASLITRIEDSGNTVIVREELVPSPGLATRQAMELAVGVKFRILRELIG
PRWRPVEVCFTHRAPLDVSAHRVFFGCKPIFNQSFNGLVCAAADLQMPRTTENAGAARFARDYLETALRQRSEGIRESCR
ELILALLPGGRCTAQQLAHHLRVDRRTLYRYLNAEGVTFSELLNEVRAELVIRHLRESDLPVGEVSALLGFSAQSCFSHW
FRVTFGCSASEWRRQTMFAGPQARAEAVLER

Specific function: May have a role in the regulation of proteins necessary for virulence [H]

COG id: COG2207

COG function: function code K; AraC-type DNA-binding domain-containing proteins

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH araC/xylS-type DNA-binding domain [H]

Homologues:

None

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009057
- InterPro:   IPR012287
- InterPro:   IPR018060 [H]

Pfam domain/function: PF00165 HTH_AraC [H]

EC number: NA

Molecular weight: Translated: 39042; Mature: 39042

Theoretical pI: Translated: 8.40; Mature: 8.40

Prosite motif: PS00041 HTH_ARAC_FAMILY_1 ; PS01124 HTH_ARAC_FAMILY_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQTASVGKLIRSASLNGYIELVESLGLDPYAFLRGVGLSARLLEDPERLIPSHAVRELLE
CCCHHHHHHHHHHCCHHHHHHHHHCCCCHHHHHHCCCCHHHHHCCHHHHCHHHHHHHHHH
VTAAATGVEDFALRLAAQRSFSNLGPISLVLKEEPTPRLALETLCRYLKLLSASLITRIE
HHHHHCCHHHHHHHHHHHHHCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHC
DSGNTVIVREELVPSPGLATRQAMELAVGVKFRILRELIGPRWRPVEVCFTHRAPLDVSA
CCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEHEEEECCCCCCCCC
HRVFFGCKPIFNQSFNGLVCAAADLQMPRTTENAGAARFARDYLETALRQRSEGIRESCR
CHHEECCCHHHCCCCCCEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
ELILALLPGGRCTAQQLAHHLRVDRRTLYRYLNAEGVTFSELLNEVRAELVIRHLRESDL
HHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCC
PVGEVSALLGFSAQSCFSHWFRVTFGCSASEWRRQTMFAGPQARAEAVLER
CHHHHHHHHCCCHHHHHHHHHHHHCCCCHHHHHHHHHCCCCHHHHHHHHCC
>Mature Secondary Structure
MQTASVGKLIRSASLNGYIELVESLGLDPYAFLRGVGLSARLLEDPERLIPSHAVRELLE
CCCHHHHHHHHHHCCHHHHHHHHHCCCCHHHHHHCCCCHHHHHCCHHHHCHHHHHHHHHH
VTAAATGVEDFALRLAAQRSFSNLGPISLVLKEEPTPRLALETLCRYLKLLSASLITRIE
HHHHHCCHHHHHHHHHHHHHCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHC
DSGNTVIVREELVPSPGLATRQAMELAVGVKFRILRELIGPRWRPVEVCFTHRAPLDVSA
CCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEHEEEECCCCCCCCC
HRVFFGCKPIFNQSFNGLVCAAADLQMPRTTENAGAARFARDYLETALRQRSEGIRESCR
CHHEECCCHHHCCCCCCEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
ELILALLPGGRCTAQQLAHHLRVDRRTLYRYLNAEGVTFSELLNEVRAELVIRHLRESDL
HHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCC
PVGEVSALLGFSAQSCFSHWFRVTFGCSASEWRRQTMFAGPQARAEAVLER
CHHHHHHHHCCCHHHHHHHHHHHHCCCCHHHHHHHHHCCCCHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8472958; 9634230; 12218036 [H]