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The map label for this gene is ydbM [H]

Identifier: 73538871

GI number: 73538871

Start: 1783171

End: 1784379

Strand: Reverse

Name: ydbM [H]

Synonym: Reut_B5046

Alternate gene names: 73538871

Gene position: 1784379-1783171 (Counterclockwise)

Preceding gene: 73538874

Following gene: 73538870

Centisome position: 65.45

GC content: 67.99

Gene sequence:

>1209_bases
ATGTCCCTGTCTTCCCTGCGCCGGCTGCCGAGCAGCGAGGCGCTGCTCGGCGATGTGCTCGCCCAGTTGACGCCTCGCCT
TGCGGCAACCGCCGCGCAGCACGACGCCGCGGCGAGCTTTCCTCACGAGAACTTCACGCTGCTGCACCAGTACGGTTTGA
TCTCGCAGGTAGTGCCGCGCCCACACGGTGGCGGCGGAGCGGGGTTGGCAGAGGCGCGCCGCATCATCGATGCGGTGGCC
AGCGGCGATGCCGCGACGGCGCTGGTGCTGACCATGACCTATCTGCAGCATCGCGCGATCGGCCGAGCCGATACGCACTG
GACCGAAGCGGTACGCAAACAGGTATTCGCGAGCGCGGTTGAAGATGGCGGACTGATCAATTCGCTGCGAGTGGAGCCAG
ACCTTGGCTCGCCTGCCCGCGGTGGCTTGCCGGGCACCGTTGCCACGCGCCTGGCGAACGGATGGCGGCTTAGCGGCCGC
AAGCTGTACAGCACCGGCATTCCGGCATTGCGCTGGCTGTCGGTCTGGGCACGCACCGACGAGCCACAGCCGCGCGTCGG
GGTGTTCCTCGTGCCCCGGCCCGGGAGGGACACGGCGGGAATCCGCATCGTGGAGAACTGGAATCACATGGGCCTGCGCG
CGTCGGGCAGCCATGAGACGGTGCTCGACAATGTGTGGATTCCGCCCGAAAACGCCGTCGACATCCGCGAGCCTTCGGCG
TGGGCGCCCGCTGGCGCCAGCCAGGCCGATGTCGATGCCAATGCGGACCAGCAGGCATGGATGGTGGTGCTGCTCGGCAG
CCTTTATGACGCCGTGGCGCGTGCGGGCTTCGACTGGATCCTCGCCTTTGTGCGGGAGCGGACACCCGGAAGCCTTGGCG
CGCCGCTCGCGACACTGCCACGCGTGCAGGAAGCGATCGGCGAAATCGCGACGCTGCTGCATGCCAACCAGGCGCTGCTC
GACGATGCCGCCGCACGCACCGACGCCGGCACCCCGCCGACACCGACCGACAGCGGACTGTTAAAGTTCACGGTGACGGG
CAATGCGATCCGCGCGGTGGAGCTGGCGCTGCAGCTGTCGGGCAACCACGGCCTGAGCCGCAACAATCCGCTGGAACGCC
ATTACCGTGACGTGCTGTGCAGCCGCATCCATACGCCGCAGAATGATTCGATCCTCGTGGCGGCCGGGCGCGTGGCGCTC
GGACAATGA

Upstream 100 bases:

>100_bases
ATGCAGGATGCGTCGTTATCGAAACGGCGCGGCGGCGGTACGCTATATGGCATTCACAAGCGGTGCGTGGCTCGCGTACC
GACCCTGCAAGGAATCCACC

Downstream 100 bases:

>100_bases
CATATCAGGAGACACGGGATGAGTGAGTCCCCCACCGCGGGCCGCGCTTCGCTGGCGCCGCTGCGCGAGTTCATCACGGG
CCTGTCGGCGCTGCTGGATG

Product: acyl-CoA dehydrogenase

Products: gamma-butyrobetaine; Acceptor; gamma-butyrobetainyl-CoA [C]

Alternate protein names: NA

Number of amino acids: Translated: 402; Mature: 401

Protein sequence:

>402_residues
MSLSSLRRLPSSEALLGDVLAQLTPRLAATAAQHDAAASFPHENFTLLHQYGLISQVVPRPHGGGGAGLAEARRIIDAVA
SGDAATALVLTMTYLQHRAIGRADTHWTEAVRKQVFASAVEDGGLINSLRVEPDLGSPARGGLPGTVATRLANGWRLSGR
KLYSTGIPALRWLSVWARTDEPQPRVGVFLVPRPGRDTAGIRIVENWNHMGLRASGSHETVLDNVWIPPENAVDIREPSA
WAPAGASQADVDANADQQAWMVVLLGSLYDAVARAGFDWILAFVRERTPGSLGAPLATLPRVQEAIGEIATLLHANQALL
DDAAARTDAGTPPTPTDSGLLKFTVTGNAIRAVELALQLSGNHGLSRNNPLERHYRDVLCSRIHTPQNDSILVAAGRVAL
GQ

Sequences:

>Translated_402_residues
MSLSSLRRLPSSEALLGDVLAQLTPRLAATAAQHDAAASFPHENFTLLHQYGLISQVVPRPHGGGGAGLAEARRIIDAVA
SGDAATALVLTMTYLQHRAIGRADTHWTEAVRKQVFASAVEDGGLINSLRVEPDLGSPARGGLPGTVATRLANGWRLSGR
KLYSTGIPALRWLSVWARTDEPQPRVGVFLVPRPGRDTAGIRIVENWNHMGLRASGSHETVLDNVWIPPENAVDIREPSA
WAPAGASQADVDANADQQAWMVVLLGSLYDAVARAGFDWILAFVRERTPGSLGAPLATLPRVQEAIGEIATLLHANQALL
DDAAARTDAGTPPTPTDSGLLKFTVTGNAIRAVELALQLSGNHGLSRNNPLERHYRDVLCSRIHTPQNDSILVAAGRVAL
GQ
>Mature_401_residues
SLSSLRRLPSSEALLGDVLAQLTPRLAATAAQHDAAASFPHENFTLLHQYGLISQVVPRPHGGGGAGLAEARRIIDAVAS
GDAATALVLTMTYLQHRAIGRADTHWTEAVRKQVFASAVEDGGLINSLRVEPDLGSPARGGLPGTVATRLANGWRLSGRK
LYSTGIPALRWLSVWARTDEPQPRVGVFLVPRPGRDTAGIRIVENWNHMGLRASGSHETVLDNVWIPPENAVDIREPSAW
APAGASQADVDANADQQAWMVVLLGSLYDAVARAGFDWILAFVRERTPGSLGAPLATLPRVQEAIGEIATLLHANQALLD
DAAARTDAGTPPTPTDSGLLKFTVTGNAIRAVELALQLSGNHGLSRNNPLERHYRDVLCSRIHTPQNDSILVAAGRVALG
Q

Specific function: Catalyzes the reduction of crotonobetainyl-CoA to gamma-butyrobetainyl-CoA. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI4557233, Length=381, Percent_Identity=23.0971128608924, Blast_Score=75, Evalue=1e-13,
Organism=Escherichia coli, GI1786223, Length=377, Percent_Identity=23.0769230769231, Blast_Score=76, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI17534899, Length=363, Percent_Identity=24.2424242424242, Blast_Score=77, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17569725, Length=385, Percent_Identity=23.6363636363636, Blast_Score=67, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24646207, Length=373, Percent_Identity=24.6648793565684, Blast_Score=85, Evalue=1e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013107
- InterPro:   IPR006092
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR013786
- InterPro:   IPR009100 [H]

Pfam domain/function: PF08028 Acyl-CoA_dh_2; PF02770 Acyl-CoA_dh_M; PF02771 Acyl-CoA_dh_N [H]

EC number: 1.3.99.- [C]

Molecular weight: Translated: 42795; Mature: 42664

Theoretical pI: Translated: 7.18; Mature: 7.18

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.2 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
1.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLSSLRRLPSSEALLGDVLAQLTPRLAATAAQHDAAASFPHENFTLLHQYGLISQVVPR
CCHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCC
PHGGGGAGLAEARRIIDAVASGDAATALVLTMTYLQHRAIGRADTHWTEAVRKQVFASAV
CCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHH
EDGGLINSLRVEPDLGSPARGGLPGTVATRLANGWRLSGRKLYSTGIPALRWLSVWARTD
HCCCCEEEEEECCCCCCCCCCCCCHHHHHHHCCCEECCCCEEECCCCHHHHHHHHHHCCC
EPQPRVGVFLVPRPGRDTAGIRIVENWNHMGLRASGSHETVLDNVWIPPENAVDIREPSA
CCCCCEEEEEECCCCCCCCCEEEEECCCCCCEEECCCCCHHHCCCCCCCCCCCCCCCCCC
WAPAGASQADVDANADQQAWMVVLLGSLYDAVARAGFDWILAFVRERTPGSLGAPLATLP
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCCCHHHHH
RVQEAIGEIATLLHANQALLDDAAARTDAGTPPTPTDSGLLKFTVTGNAIRAVELALQLS
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEEECCCEEEEEEEEEEC
GNHGLSRNNPLERHYRDVLCSRIHTPQNDSILVAAGRVALGQ
CCCCCCCCCCHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCC
>Mature Secondary Structure 
SLSSLRRLPSSEALLGDVLAQLTPRLAATAAQHDAAASFPHENFTLLHQYGLISQVVPR
CHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCC
PHGGGGAGLAEARRIIDAVASGDAATALVLTMTYLQHRAIGRADTHWTEAVRKQVFASAV
CCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHH
EDGGLINSLRVEPDLGSPARGGLPGTVATRLANGWRLSGRKLYSTGIPALRWLSVWARTD
HCCCCEEEEEECCCCCCCCCCCCCHHHHHHHCCCEECCCCEEECCCCHHHHHHHHHHCCC
EPQPRVGVFLVPRPGRDTAGIRIVENWNHMGLRASGSHETVLDNVWIPPENAVDIREPSA
CCCCCEEEEEECCCCCCCCCEEEEECCCCCCEEECCCCCHHHCCCCCCCCCCCCCCCCCC
WAPAGASQADVDANADQQAWMVVLLGSLYDAVARAGFDWILAFVRERTPGSLGAPLATLP
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCCCHHHHH
RVQEAIGEIATLLHANQALLDDAAARTDAGTPPTPTDSGLLKFTVTGNAIRAVELALQLS
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEEECCCEEEEEEEEEEC
GNHGLSRNNPLERHYRDVLCSRIHTPQNDSILVAAGRVALGQ
CCCCCCCCCCHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: crotono-betaine; reduced acceptor; crotonobetainyl-CoA [C]

Specific reaction: reduced acceptor + crotono-betaine = Acceptor + gamma-butyrobetaine reduced acceptor + crotonobetainyl-CoA = Acceptor + gamma-butyrobetainyl-CoA [C]

General reaction: Oxidoreductases; Acting on the CH-CH group of donors; With other acceptors [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]