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The map label for this gene is panE [C]

Identifier: 73538792

GI number: 73538792

Start: 1694365

End: 1695264

Strand: Reverse

Name: panE [C]

Synonym: Reut_B4967

Alternate gene names: 73538792

Gene position: 1695264-1694365 (Counterclockwise)

Preceding gene: 73538804

Following gene: 73538791

Centisome position: 62.19

GC content: 65.78

Gene sequence:

>900_bases
ATGAAAGTCGCCATCATGGGCGCCGGAGCCGTCGGCTGCTACTACGGCGGAATGCTAGCGAGGGCCGGCCACGAAGTCAT
CCTGATCGCCCGCCCGCAACACGTACAGGCCATCGAAGCAACCGGCCTGCGGCTCGAAACGCAATCGTTCGATGAACAGG
TCAAGGTGTCGGCCAGCTCGGACCCCAGCGCCGTACAGGGCGCTGACCTCGTCCTCTTCTGCGTGAAATCGACCGACACC
CAAAGCGCCGCGCTGGCGATGAAGCCGGCGCTTGCCAAGAGCGCGCTGGTGCTGTCGCTACAGAATGGCGTGGAGAACGC
CGACACGCTGCGCAGCCTGCTGGAGCAGGAGGTGGCCGCGGCAGTGGTCTACGTGGCTACTGAAATGGCTGGCCCCGGAC
ATGTCAGGCACCACGGCCGCGGCGAACTCGTGATCGAGCCGACCAGTCACGGCGCAAACCTAGCCGCGATATTTGCCGCC
GCAGGCGTGCCAGTCGAAACCTCCGACAATGTGCGCGGCGCGCTGTGGGCCAAGCTGATCCTGAACTGCGCATACAACGC
ACTGTCGGCCATTACGCAACTGCCATACGGACGCCTTGTTCGCGGCGAGGGCGTCGAGGCCGTGATGCGCGACGTGATGG
AGGAATGCTTCGCCGTCGCGCGCGCCGAAGGCGTGAAGCTGCCCGACGATGTCGCGCTGGCGATCCGCCGCATTGCGGAG
ACCATGCCCGGACAGTCGTCATCGACGGCGCAGGACCTCGCGCGCGGCAAGCGCAGCGAGATCGATCATCTCAACGGCCT
GATCGTGCGCCGCGGCGACGCGCTGGGCATCCCAGTGCCAGCCAACCGGGTGCTGCACGCACTGGTAAGGCTGATCGAGG
ACAAGCAGCAACACGGCTGA

Upstream 100 bases:

>100_bases
GCAAGCCCCCGCCGAAGACCCCGGCAAAAACAGCGATCACCCGCCGAGAACCCTGCCCCTGCCATAATCCTTCATCCCAA
CCCCCCGGAGCATGACAATC

Downstream 100 bases:

>100_bases
TTGCTGTCCAGATGTGGGGGTGGCAAATGTCCCGACATGGATATGCGCCGGCCGCATAAGGCCCAGCGATATCATTCCTT
GACCCTGCCATTGCCCGTTC

Product: ketopantoate reductase ApbA/PanE

Products: NA

Alternate protein names: Ketopantoate reductase; KPA reductase; KPR [H]

Number of amino acids: Translated: 299; Mature: 299

Protein sequence:

>299_residues
MKVAIMGAGAVGCYYGGMLARAGHEVILIARPQHVQAIEATGLRLETQSFDEQVKVSASSDPSAVQGADLVLFCVKSTDT
QSAALAMKPALAKSALVLSLQNGVENADTLRSLLEQEVAAAVVYVATEMAGPGHVRHHGRGELVIEPTSHGANLAAIFAA
AGVPVETSDNVRGALWAKLILNCAYNALSAITQLPYGRLVRGEGVEAVMRDVMEECFAVARAEGVKLPDDVALAIRRIAE
TMPGQSSSTAQDLARGKRSEIDHLNGLIVRRGDALGIPVPANRVLHALVRLIEDKQQHG

Sequences:

>Translated_299_residues
MKVAIMGAGAVGCYYGGMLARAGHEVILIARPQHVQAIEATGLRLETQSFDEQVKVSASSDPSAVQGADLVLFCVKSTDT
QSAALAMKPALAKSALVLSLQNGVENADTLRSLLEQEVAAAVVYVATEMAGPGHVRHHGRGELVIEPTSHGANLAAIFAA
AGVPVETSDNVRGALWAKLILNCAYNALSAITQLPYGRLVRGEGVEAVMRDVMEECFAVARAEGVKLPDDVALAIRRIAE
TMPGQSSSTAQDLARGKRSEIDHLNGLIVRRGDALGIPVPANRVLHALVRLIEDKQQHG
>Mature_299_residues
MKVAIMGAGAVGCYYGGMLARAGHEVILIARPQHVQAIEATGLRLETQSFDEQVKVSASSDPSAVQGADLVLFCVKSTDT
QSAALAMKPALAKSALVLSLQNGVENADTLRSLLEQEVAAAVVYVATEMAGPGHVRHHGRGELVIEPTSHGANLAAIFAA
AGVPVETSDNVRGALWAKLILNCAYNALSAITQLPYGRLVRGEGVEAVMRDVMEECFAVARAEGVKLPDDVALAIRRIAE
TMPGQSSSTAQDLARGKRSEIDHLNGLIVRRGDALGIPVPANRVLHALVRLIEDKQQHG

Specific function: Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid [H]

COG id: COG1893

COG function: function code H; Ketopantoate reductase

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ketopantoate reductase family [H]

Homologues:

Organism=Escherichia coli, GI1786627, Length=310, Percent_Identity=28.3870967741935, Blast_Score=96, Evalue=3e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008927
- InterPro:   IPR003710
- InterPro:   IPR013752
- InterPro:   IPR013332
- InterPro:   IPR013328
- InterPro:   IPR016040 [H]

Pfam domain/function: PF02558 ApbA; PF08546 ApbA_C [H]

EC number: =1.1.1.169 [H]

Molecular weight: Translated: 31534; Mature: 31534

Theoretical pI: Translated: 6.60; Mature: 6.60

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKVAIMGAGAVGCYYGGMLARAGHEVILIARPQHVQAIEATGLRLETQSFDEQVKVSASS
CEEEEEECCHHHHHHHHHHHHCCCCEEEEECCCHHHHHHHCCCEEECCCCCCCEEEECCC
DPSAVQGADLVLFCVKSTDTQSAALAMKPALAKSALVLSLQNGVENADTLRSLLEQEVAA
CCCCCCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHEEEHHCCCCCHHHHHHHHHHHHHH
AVVYVATEMAGPGHVRHHGRGELVIEPTSHGANLAAIFAAAGVPVETSDNVRGALWAKLI
HHHHHHHHCCCCCCCCCCCCCCEEEEECCCCCCHHHHHHHCCCCCCCCCCCHHHHHHHHH
LNCAYNALSAITQLPYGRLVRGEGVEAVMRDVMEECFAVARAEGVKLPDDVALAIRRIAE
HHHHHHHHHHHHHCCCCCEECCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHH
TMPGQSSSTAQDLARGKRSEIDHLNGLIVRRGDALGIPVPANRVLHALVRLIEDKQQHG
HCCCCCCCHHHHHHCCCHHHHHHHCCEEEECCCCCCCCCCHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MKVAIMGAGAVGCYYGGMLARAGHEVILIARPQHVQAIEATGLRLETQSFDEQVKVSASS
CEEEEEECCHHHHHHHHHHHHCCCCEEEEECCCHHHHHHHCCCEEECCCCCCCEEEECCC
DPSAVQGADLVLFCVKSTDTQSAALAMKPALAKSALVLSLQNGVENADTLRSLLEQEVAA
CCCCCCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHEEEHHCCCCCHHHHHHHHHHHHHH
AVVYVATEMAGPGHVRHHGRGELVIEPTSHGANLAAIFAAAGVPVETSDNVRGALWAKLI
HHHHHHHHCCCCCCCCCCCCCCEEEEECCCCCCHHHHHHHCCCCCCCCCCCHHHHHHHHH
LNCAYNALSAITQLPYGRLVRGEGVEAVMRDVMEECFAVARAEGVKLPDDVALAIRRIAE
HHHHHHHHHHHHHCCCCCEECCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHH
TMPGQSSSTAQDLARGKRSEIDHLNGLIVRRGDALGIPVPANRVLHALVRLIEDKQQHG
HCCCCCCCHHHHHHCCCHHHHHHHCCEEEECCCCCCCCCCHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9389475 [H]