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The map label for this gene is mhpT [H]

Identifier: 73538697

GI number: 73538697

Start: 1587966

End: 1589180

Strand: Reverse

Name: mhpT [H]

Synonym: Reut_B4872

Alternate gene names: 73538697

Gene position: 1589180-1587966 (Counterclockwise)

Preceding gene: 73538698

Following gene: 73538696

Centisome position: 58.29

GC content: 66.83

Gene sequence:

>1215_bases
ATGCAAACTTCAACCGTAGTACGCGCCGAGGCAACCTCGGGCGCGGCGCTGACGCTCGGTCTCTGCTTTGTCGTCGCGCT
GCTGGAAGGGCTCGATTTGCAGTCGATCGGTGTCGCCGCGCCCCGCATGGCGCGGGAGTTCGGCCTGTCGGTCAGCGAGA
TGGGACTGGCGTTCAGCGCCGGGACGTTCGGCCTGCTGCCCGGCGCCATGCTGGGCGGACGGCTGGCCGACCGCATCGGA
CGCAAGCGTGTGCTGATCGTAGCCACCGCGCTGTTCGGCATCTTTTCCATCGCGACGGCGCACACCGTCGACTTCTGGAG
CCTGCTGGCCATCCGTGTCGCCACCGGCATGGGTCTGGGCGGCGCCATGCCGAACCTGATTGCGATCTGCTCGGAATCGG
TGCCGGCCAGGCTGCGCAATACCGCCGTCAGCATCATGTACTGCGGCATCCCGTTCGGCGGCGCCGTGGCGGCGGTGATT
GGCATTCTCTCCGCCGGAGACACCGGATGGCGCCACATTTTCTATGTCGGCGGCTTTGGGCCGCTGCTCGTCGTGCCGCT
GCTGCTGATGCTGCAGGACTCGCGTCGTTTCGATCCGCCGCACGGTGAGTCGGTGAAGCCGCCGCCGGTGGCGTGGGCGC
TCTTCGGGGAGCGCCGCGCGATGGCCACCGCATGCATCTGGATCAGCTACTTCTTCACCCTGATCGTGCTGTATTTCCTG
CTGAACTGGCTGCCGTCGCTGATGGTGGCGAACGGCCTGAGCCGGCCACAGGCGGGTGTAGTGCAGATCGTGTTCAACAT
CGGCGGTGGCGTCGGAGCGCTAGGCATCGGGATGCTGATGGATAAGGGTCGCCCGCGTGCGGTGGTGTCGGGCATGTATG
CGGGGATTATCGTCGCGCTCGCCACGCTGGCGGCCGCTTCGGGCATGACCTGGATGGCACTCGGCGCCTTCCTGGCAGGC
CTGTTCGTCATCGGTGCGCAGTCGGTGCTCTATGCGCTGGCAGCCGCGTATTACCCGATGGCGGTGCGCGGCACCGGCGT
GGGCACCGCAGTCGCGGTGGGGCGGCTCGGGTCCATCGCGGGACCCATGCTGGCGGGGCAACTGCTGGCCATGGGCAAGA
ACGCGAGCACGATCATCGGCGCAAGTATTCCGATCACCATCATCTCGGCCGTTGCCGCATTGCTGCTGTTGCAGCGGCCC
GCGGCTAAAGACTGA

Upstream 100 bases:

>100_bases
TGCGCGTATCCGAAGACGGCGCGCTACGCCGGCTCCGGCGACATCAACGATGCGGCCAACTTCCGCTGCCTCTGACTTCC
GCGCCAAGCAAGGAACCACC

Downstream 100 bases:

>100_bases
CCAGGGCAACAAGAGATCACAAGAGAAGGAAGGAGAAAGCGAGACAATGAAACGCAAGAGCATTCACCGTGCCGGCCAGG
GGTTCCTGGCGCTGGCGGCG

Product: putative 3-hydroxyphenylpropionic transporter MhpT

Products: Proton [Cytoplasm]; 3-(3-hydroxyphenyl)propionate [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 404; Mature: 404

Protein sequence:

>404_residues
MQTSTVVRAEATSGAALTLGLCFVVALLEGLDLQSIGVAAPRMAREFGLSVSEMGLAFSAGTFGLLPGAMLGGRLADRIG
RKRVLIVATALFGIFSIATAHTVDFWSLLAIRVATGMGLGGAMPNLIAICSESVPARLRNTAVSIMYCGIPFGGAVAAVI
GILSAGDTGWRHIFYVGGFGPLLVVPLLLMLQDSRRFDPPHGESVKPPPVAWALFGERRAMATACIWISYFFTLIVLYFL
LNWLPSLMVANGLSRPQAGVVQIVFNIGGGVGALGIGMLMDKGRPRAVVSGMYAGIIVALATLAAASGMTWMALGAFLAG
LFVIGAQSVLYALAAAYYPMAVRGTGVGTAVAVGRLGSIAGPMLAGQLLAMGKNASTIIGASIPITIISAVAALLLLQRP
AAKD

Sequences:

>Translated_404_residues
MQTSTVVRAEATSGAALTLGLCFVVALLEGLDLQSIGVAAPRMAREFGLSVSEMGLAFSAGTFGLLPGAMLGGRLADRIG
RKRVLIVATALFGIFSIATAHTVDFWSLLAIRVATGMGLGGAMPNLIAICSESVPARLRNTAVSIMYCGIPFGGAVAAVI
GILSAGDTGWRHIFYVGGFGPLLVVPLLLMLQDSRRFDPPHGESVKPPPVAWALFGERRAMATACIWISYFFTLIVLYFL
LNWLPSLMVANGLSRPQAGVVQIVFNIGGGVGALGIGMLMDKGRPRAVVSGMYAGIIVALATLAAASGMTWMALGAFLAG
LFVIGAQSVLYALAAAYYPMAVRGTGVGTAVAVGRLGSIAGPMLAGQLLAMGKNASTIIGASIPITIISAVAALLLLQRP
AAKD
>Mature_404_residues
MQTSTVVRAEATSGAALTLGLCFVVALLEGLDLQSIGVAAPRMAREFGLSVSEMGLAFSAGTFGLLPGAMLGGRLADRIG
RKRVLIVATALFGIFSIATAHTVDFWSLLAIRVATGMGLGGAMPNLIAICSESVPARLRNTAVSIMYCGIPFGGAVAAVI
GILSAGDTGWRHIFYVGGFGPLLVVPLLLMLQDSRRFDPPHGESVKPPPVAWALFGERRAMATACIWISYFFTLIVLYFL
LNWLPSLMVANGLSRPQAGVVQIVFNIGGGVGALGIGMLMDKGRPRAVVSGMYAGIIVALATLAAASGMTWMALGAFLAG
LFVIGAQSVLYALAAAYYPMAVRGTGVGTAVAVGRLGSIAGPMLAGQLLAMGKNASTIIGASIPITIISAVAALLLLQRP
AAKD

Specific function: Could be a transporter for 3-phenylpropionate (hydrocinnamic acid) [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family [H]

Homologues:

Organism=Escherichia coli, GI87081723, Length=384, Percent_Identity=50, Blast_Score=325, Evalue=4e-90,
Organism=Escherichia coli, GI1789152, Length=393, Percent_Identity=23.9185750636132, Blast_Score=82, Evalue=9e-17,
Organism=Escherichia coli, GI87082231, Length=430, Percent_Identity=23.7209302325581, Blast_Score=71, Evalue=2e-13,
Organism=Escherichia coli, GI87082320, Length=386, Percent_Identity=23.5751295336788, Blast_Score=66, Evalue=3e-12,
Organism=Escherichia coli, GI87082404, Length=301, Percent_Identity=25.5813953488372, Blast_Score=65, Evalue=6e-12,
Organism=Escherichia coli, GI1786229, Length=361, Percent_Identity=23.5457063711911, Blast_Score=63, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004746
- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196
- InterPro:   IPR005829 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 41596; Mature: 41596

Theoretical pI: Translated: 10.28; Mature: 10.28

Prosite motif: PS50850 MFS ; PS00216 SUGAR_TRANSPORT_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
4.5 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
4.5 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQTSTVVRAEATSGAALTLGLCFVVALLEGLDLQSIGVAAPRMAREFGLSVSEMGLAFSA
CCCCCEEEEECCCCHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHCCCHHHHCCEECC
GTFGLLPGAMLGGRLADRIGRKRVLIVATALFGIFSIATAHTVDFWSLLAIRVATGMGLG
CCHHHCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
GAMPNLIAICSESVPARLRNTAVSIMYCGIPFGGAVAAVIGILSAGDTGWRHIFYVGGFG
CCHHHHHHHHCCCCCHHHHHHEEEEEEECCCCHHHHHHHHHHHCCCCCCCEEEEEECCCH
PLLVVPLLLMLQDSRRFDPPHGESVKPPPVAWALFGERRAMATACIWISYFFTLIVLYFL
HHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHH
LNWLPSLMVANGLSRPQAGVVQIVFNIGGGVGALGIGMLMDKGRPRAVVSGMYAGIIVAL
HHHHHHHHHHCCCCCCCCCCEEEEEECCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHH
ATLAAASGMTWMALGAFLAGLFVIGAQSVLYALAAAYYPMAVRGTGVGTAVAVGRLGSIA
HHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCHHHHHHHHHHHHH
GPMLAGQLLAMGKNASTIIGASIPITIISAVAALLLLQRPAAKD
HHHHHHHHHHCCCCCCEEECCCCHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MQTSTVVRAEATSGAALTLGLCFVVALLEGLDLQSIGVAAPRMAREFGLSVSEMGLAFSA
CCCCCEEEEECCCCHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHCCCHHHHCCEECC
GTFGLLPGAMLGGRLADRIGRKRVLIVATALFGIFSIATAHTVDFWSLLAIRVATGMGLG
CCHHHCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
GAMPNLIAICSESVPARLRNTAVSIMYCGIPFGGAVAAVIGILSAGDTGWRHIFYVGGFG
CCHHHHHHHHCCCCCHHHHHHEEEEEEECCCCHHHHHHHHHHHCCCCCCCEEEEEECCCH
PLLVVPLLLMLQDSRRFDPPHGESVKPPPVAWALFGERRAMATACIWISYFFTLIVLYFL
HHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHH
LNWLPSLMVANGLSRPQAGVVQIVFNIGGGVGALGIGMLMDKGRPRAVVSGMYAGIIVAL
HHHHHHHHHHCCCCCCCCCCEEEEEECCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHH
ATLAAASGMTWMALGAFLAGLFVIGAQSVLYALAAAYYPMAVRGTGVGTAVAVGRLGSIA
HHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCHHHHHHHHHHHHH
GPMLAGQLLAMGKNASTIIGASIPITIISAVAALLLLQRPAAKD
HHHHHHHHHHCCCCCCEEECCCCHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; 3-(3-hydroxyphenyl)propionate [Periplasm] [C]

Specific reaction: Proton [Periplasm] + 3-(3-hydroxyphenyl)propionate [Periplasm] = Proton [Cytoplasm] + 3-(3-hydroxyphenyl)propionate [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]