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The map label for this gene is 73538646

Identifier: 73538646

GI number: 73538646

Start: 1523593

End: 1524564

Strand: Reverse

Name: 73538646

Synonym: Reut_B4821

Alternate gene names: NA

Gene position: 1524564-1523593 (Counterclockwise)

Preceding gene: 73538647

Following gene: 73538645

Centisome position: 55.92

GC content: 61.11

Gene sequence:

>972_bases
ATGAGCCCGCTGCACCAGGACAGCATCATTATCGACGGCCTGAACATCTCGAAGTTCGAGCGGTCGGTGTTCGAAGACAT
GAAGAAGGGCGGCGTCACGGCCGCGAACTGTACGGTCTCGGTCTGGGACAATTTCACCAAGACCGTCGACAACATTGCGC
TGATGAAGCAGGCGATTCGCGACAACAGCGAACTGCTGACGCTCGTGCGCACCACGGAAGATATCCGCCGTGCAAAGCAT
GAGGGCAAGACCGGCGTGATCCTCGGCTTCCAGAACGCGCACGCTTTCGAGGACAACCTCGGCTATGTCGAAGCGTTCGC
CGACATGGGCGTGCGCGTCGTGCAACTCTGCTACAACACGCAGAACCTGGTGGGCACCGGATGCTACGAGCGCGACGGCG
GCCTGTCGGACTTCGGCCGCGAGGTGATCACCGAGATGAACCGCGTCGGGATCATGGTCGATCTGTCGCACGTTGGGGGC
AACACTTCGTCCGAGGCGATTGCGTTCTCGAAAAAGCCGGTCTGCTACTCGCACTGTCTGCCGTCGGGCCTCAAGGAACA
TCCGCGCAACAAGAGCGATGCGCAGCTGAAGGAGATCGCCGATGCGGGCGGCTTCGTCGGCGTGACGATGTTCGCGCCGT
TCCTCAAGCGCGGAATCGAGGCGACGGTCGACGACTACATCGAAGCGATCGACTACGTGGTCAACCTCATCGGCGAGGAT
GCGGTCGGCATCGGCACCGACTTCACGCAGGGCTACAGCACCGAGTTCTTCGACATGCTGACGCATGACAAGGGCCGCTA
CCGGCGCCTGACCAACTTCGGCAAGGTGATCAACCCTGAAGGGATCCGCACCATCGGCGATTTTCCGAACCTGACCGCGG
CGATGGAACGAGCTGGCTGGAAGGCATCTCGCATCCGCAAGATCATGGGCGAGAACTGGGTGCGCATCTTCAAGGAAGTG
TGGGGCGCCTGA

Upstream 100 bases:

>100_bases
CGACGCTGTCACCGAGCAGCGCGTGCGCCAGCAAATCTTCGCGCTGTGCGATCGCTTCCCGATCTACTGACCCGAACGAA
CGATAAGACTGGAGCCCCCC

Downstream 100 bases:

>100_bases
CCCCCGCACCGCGCCAGCTTTCCATCAAATCACCACAAACGGGACGGGCGTGCGCGATAGCGCGCGCTCGCGGGCGACGC
CGCGTCTACGCAACGCTACC

Product: membrane dipeptidase

Products: NA

Alternate protein names: ORF X [H]

Number of amino acids: Translated: 323; Mature: 322

Protein sequence:

>323_residues
MSPLHQDSIIIDGLNISKFERSVFEDMKKGGVTAANCTVSVWDNFTKTVDNIALMKQAIRDNSELLTLVRTTEDIRRAKH
EGKTGVILGFQNAHAFEDNLGYVEAFADMGVRVVQLCYNTQNLVGTGCYERDGGLSDFGREVITEMNRVGIMVDLSHVGG
NTSSEAIAFSKKPVCYSHCLPSGLKEHPRNKSDAQLKEIADAGGFVGVTMFAPFLKRGIEATVDDYIEAIDYVVNLIGED
AVGIGTDFTQGYSTEFFDMLTHDKGRYRRLTNFGKVINPEGIRTIGDFPNLTAAMERAGWKASRIRKIMGENWVRIFKEV
WGA

Sequences:

>Translated_323_residues
MSPLHQDSIIIDGLNISKFERSVFEDMKKGGVTAANCTVSVWDNFTKTVDNIALMKQAIRDNSELLTLVRTTEDIRRAKH
EGKTGVILGFQNAHAFEDNLGYVEAFADMGVRVVQLCYNTQNLVGTGCYERDGGLSDFGREVITEMNRVGIMVDLSHVGG
NTSSEAIAFSKKPVCYSHCLPSGLKEHPRNKSDAQLKEIADAGGFVGVTMFAPFLKRGIEATVDDYIEAIDYVVNLIGED
AVGIGTDFTQGYSTEFFDMLTHDKGRYRRLTNFGKVINPEGIRTIGDFPNLTAAMERAGWKASRIRKIMGENWVRIFKEV
WGA
>Mature_322_residues
SPLHQDSIIIDGLNISKFERSVFEDMKKGGVTAANCTVSVWDNFTKTVDNIALMKQAIRDNSELLTLVRTTEDIRRAKHE
GKTGVILGFQNAHAFEDNLGYVEAFADMGVRVVQLCYNTQNLVGTGCYERDGGLSDFGREVITEMNRVGIMVDLSHVGGN
TSSEAIAFSKKPVCYSHCLPSGLKEHPRNKSDAQLKEIADAGGFVGVTMFAPFLKRGIEATVDDYIEAIDYVVNLIGEDA
VGIGTDFTQGYSTEFFDMLTHDKGRYRRLTNFGKVINPEGIRTIGDFPNLTAAMERAGWKASRIRKIMGENWVRIFKEVW
GA

Specific function: Unknown

COG id: COG2355

COG function: function code E; Zn-dependent dipeptidase, microsomal dipeptidase homolog

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M19 family [H]

Homologues:

Organism=Homo sapiens, GI189458885, Length=291, Percent_Identity=25.085910652921, Blast_Score=118, Evalue=6e-27,
Organism=Homo sapiens, GI4758190, Length=291, Percent_Identity=25.085910652921, Blast_Score=118, Evalue=6e-27,
Organism=Homo sapiens, GI11641269, Length=291, Percent_Identity=25.085910652921, Blast_Score=109, Evalue=3e-24,
Organism=Homo sapiens, GI193211608, Length=279, Percent_Identity=22.9390681003584, Blast_Score=93, Evalue=3e-19,
Organism=Homo sapiens, GI193211610, Length=279, Percent_Identity=22.9390681003584, Blast_Score=90, Evalue=2e-18,
Organism=Drosophila melanogaster, GI281362638, Length=318, Percent_Identity=29.2452830188679, Blast_Score=140, Evalue=1e-33,
Organism=Drosophila melanogaster, GI281362636, Length=318, Percent_Identity=29.2452830188679, Blast_Score=140, Evalue=1e-33,
Organism=Drosophila melanogaster, GI221475880, Length=317, Percent_Identity=26.813880126183, Blast_Score=121, Evalue=7e-28,
Organism=Drosophila melanogaster, GI161083233, Length=310, Percent_Identity=25.1612903225806, Blast_Score=110, Evalue=2e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008257 [H]

Pfam domain/function: PF01244 Peptidase_M19 [H]

EC number: NA

Molecular weight: Translated: 35813; Mature: 35682

Theoretical pI: Translated: 5.93; Mature: 5.93

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSPLHQDSIIIDGLNISKFERSVFEDMKKGGVTAANCTVSVWDNFTKTVDNIALMKQAIR
CCCCCCCCEEEECCCHHHHHHHHHHHHHHCCCEEECCEEHHHHHHHHHHHHHHHHHHHHH
DNSELLTLVRTTEDIRRAKHEGKTGVILGFQNAHAFEDNLGYVEAFADMGVRVVQLCYNT
CCHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCHHHCCCHHHHHHHHHHHHHHHHHHCC
QNLVGTGCYERDGGLSDFGREVITEMNRVGIMVDLSHVGGNTSSEAIAFSKKPVCYSHCL
CHHHCCCCCCCCCCHHHHHHHHHHHHHHCEEEEEEHHCCCCCCCCCEEECCCCCHHHHHC
PSGLKEHPRNKSDAQLKEIADAGGFVGVTMFAPFLKRGIEATVDDYIEAIDYVVNLIGED
CCHHHHCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCC
AVGIGTDFTQGYSTEFFDMLTHDKGRYRRLTNFGKVINPEGIRTIGDFPNLTAAMERAGW
CCCCCCCCCCCCCHHHHHHHHCCCHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHCCC
KASRIRKIMGENWVRIFKEVWGA
HHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SPLHQDSIIIDGLNISKFERSVFEDMKKGGVTAANCTVSVWDNFTKTVDNIALMKQAIR
CCCCCCCEEEECCCHHHHHHHHHHHHHHCCCEEECCEEHHHHHHHHHHHHHHHHHHHHH
DNSELLTLVRTTEDIRRAKHEGKTGVILGFQNAHAFEDNLGYVEAFADMGVRVVQLCYNT
CCHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCHHHCCCHHHHHHHHHHHHHHHHHHCC
QNLVGTGCYERDGGLSDFGREVITEMNRVGIMVDLSHVGGNTSSEAIAFSKKPVCYSHCL
CHHHCCCCCCCCCCHHHHHHHHHHHHHHCEEEEEEHHCCCCCCCCCEEECCCCCHHHHHC
PSGLKEHPRNKSDAQLKEIADAGGFVGVTMFAPFLKRGIEATVDDYIEAIDYVVNLIGED
CCHHHHCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCC
AVGIGTDFTQGYSTEFFDMLTHDKGRYRRLTNFGKVINPEGIRTIGDFPNLTAAMERAGW
CCCCCCCCCCCCCHHHHHHHHCCCHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHCCC
KASRIRKIMGENWVRIFKEVWGA
HHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1313537 [H]