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The map label for this gene is 73538497

Identifier: 73538497

GI number: 73538497

Start: 1366554

End: 1367531

Strand: Reverse

Name: 73538497

Synonym: Reut_B4671

Alternate gene names: NA

Gene position: 1367531-1366554 (Counterclockwise)

Preceding gene: 73538501

Following gene: 73538496

Centisome position: 50.16

GC content: 64.83

Gene sequence:

>978_bases
ATGAAAGTGTGCATCTATGGGGCAGGGGCCATCGGCGGCTATGTGGGCGCCCAACTGGCGCGCGCGGGGGCCGAAGTCAG
CTTCGTCGCGCGCGGTCCGCACCTGGCGGCCATGAAGGCCAACGGCGTTCGGCTGCTGATCGACGGCGAGGAGCGGGTGG
CCAGGGTCAACTGCACGAGTGATCCGCGCGAACTCGGTCCCCAGGATTATGTGTTTATCACGCTCAAGGCGCATTCGGTG
CCCGGCGTGGTGGATCTGATGCAGCCGCTGCTGGGACCGCAGACGGCGGTAGTCACGGGCGTCAACGGTATTCCTTACTG
GTATTTCTACAAGCATGGCGGCGAACTGGCGGGCAGCACGCTCGAAAGTGTGGACCCGGGCGGCAAGCAGTGGCGCGGCT
TCGGCCCCGAGCGTGCGATCGGTTGCGTCGTCTATCCCGCCGCGGAAATCATCGAACCGGGCGTGATCAAGCATGTGTAT
GGCAAGAAATTCCCGCTTGGCGAGCCGGATGGCAGCCAGTCGGACCGCGTCACACGACTGAGCGAGATGATGATGGCGGC
TGACCTGGAAGCGCCGGTGCGAGAAAACATCCGCGATGAAATCTGGCTCAAGCTGTGGGGCAACCTCTGTTTCAACCCGA
TCAGTGCGCTGACCCACGCCACCTTGGACGTCATCACAGCAAATCCCGCCACGCGGGCCCTGTCGCGCCAGATGATGCTG
GAGGCCCAGAGCATTGCCGAGTCATTCGGCGTGAAATTCCGCGTGGACGTCGAGCGCCGCATCAACGGCGCGGGCGCCGT
GGGCGCCCACAAGACGTCGATGCTGCAGGACCTGGAGGCGGGCCGCGCGATGGAAATCGACCCGTTGCTCACCGTCGTGC
AGGAGATGGGCCGCCTGGTCGGCCATCCGACGCCGATGTGCGATGCAGTACTGGGCCTCATCAAGCAGCGCGACGAAATG
GCGCGCCTGGCGGCCTGA

Upstream 100 bases:

>100_bases
TAGTTCGCTTGCGAGCGAAAATTAGGGTTGTCGTTCGGCCTTGTGGAATATAGTATGTGATATATCAATGAATACTATCG
AGCCATCAAGGAGACAGGCA

Downstream 100 bases:

>100_bases
TCGTCGGCATGACCTACGCCCCGTGCCACAGCCCGCGTGGCCGGGGCGCATTTGATGCATGCAAGTCCGCCGGGAAAGTC
ACCTTTTCGTGGCTTACCGC

Product: 2-dehydropantoate 2-reductase

Products: NA

Alternate protein names: Ketopantoate reductase; KPA reductase; KPR [H]

Number of amino acids: Translated: 325; Mature: 325

Protein sequence:

>325_residues
MKVCIYGAGAIGGYVGAQLARAGAEVSFVARGPHLAAMKANGVRLLIDGEERVARVNCTSDPRELGPQDYVFITLKAHSV
PGVVDLMQPLLGPQTAVVTGVNGIPYWYFYKHGGELAGSTLESVDPGGKQWRGFGPERAIGCVVYPAAEIIEPGVIKHVY
GKKFPLGEPDGSQSDRVTRLSEMMMAADLEAPVRENIRDEIWLKLWGNLCFNPISALTHATLDVITANPATRALSRQMML
EAQSIAESFGVKFRVDVERRINGAGAVGAHKTSMLQDLEAGRAMEIDPLLTVVQEMGRLVGHPTPMCDAVLGLIKQRDEM
ARLAA

Sequences:

>Translated_325_residues
MKVCIYGAGAIGGYVGAQLARAGAEVSFVARGPHLAAMKANGVRLLIDGEERVARVNCTSDPRELGPQDYVFITLKAHSV
PGVVDLMQPLLGPQTAVVTGVNGIPYWYFYKHGGELAGSTLESVDPGGKQWRGFGPERAIGCVVYPAAEIIEPGVIKHVY
GKKFPLGEPDGSQSDRVTRLSEMMMAADLEAPVRENIRDEIWLKLWGNLCFNPISALTHATLDVITANPATRALSRQMML
EAQSIAESFGVKFRVDVERRINGAGAVGAHKTSMLQDLEAGRAMEIDPLLTVVQEMGRLVGHPTPMCDAVLGLIKQRDEM
ARLAA
>Mature_325_residues
MKVCIYGAGAIGGYVGAQLARAGAEVSFVARGPHLAAMKANGVRLLIDGEERVARVNCTSDPRELGPQDYVFITLKAHSV
PGVVDLMQPLLGPQTAVVTGVNGIPYWYFYKHGGELAGSTLESVDPGGKQWRGFGPERAIGCVVYPAAEIIEPGVIKHVY
GKKFPLGEPDGSQSDRVTRLSEMMMAADLEAPVRENIRDEIWLKLWGNLCFNPISALTHATLDVITANPATRALSRQMML
EAQSIAESFGVKFRVDVERRINGAGAVGAHKTSMLQDLEAGRAMEIDPLLTVVQEMGRLVGHPTPMCDAVLGLIKQRDEM
ARLAA

Specific function: Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid [H]

COG id: COG1893

COG function: function code H; Ketopantoate reductase

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ketopantoate reductase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008927
- InterPro:   IPR003710
- InterPro:   IPR013752
- InterPro:   IPR013332
- InterPro:   IPR013328
- InterPro:   IPR016040 [H]

Pfam domain/function: PF02558 ApbA; PF08546 ApbA_C [H]

EC number: =1.1.1.169 [H]

Molecular weight: Translated: 35032; Mature: 35032

Theoretical pI: Translated: 6.63; Mature: 6.63

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
5.5 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
5.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKVCIYGAGAIGGYVGAQLARAGAEVSFVARGPHLAAMKANGVRLLIDGEERVARVNCTS
CEEEEEECCHHHHHHHHHHHHCCCCEEEEECCCEEEEEECCCEEEEEECCCCEEEEECCC
DPRELGPQDYVFITLKAHSVPGVVDLMQPLLGPQTAVVTGVNGIPYWYFYKHGGELAGST
CHHHCCCCCEEEEEEEECCCCCHHHHHHHHCCCCCEEEECCCCCCEEEEEECCCCCCCCH
LESVDPGGKQWRGFGPERAIGCVVYPAAEIIEPGVIKHVYGKKFPLGEPDGSQSDRVTRL
HHHCCCCCCCCCCCCCCCCEEEEEECHHHHHCCCHHHHHCCCCCCCCCCCCCCHHHHHHH
SEMMMAADLEAPVRENIRDEIWLKLWGNLCFNPISALTHATLDVITANPATRALSRQMML
HHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCHHHHHHHHHHHH
EAQSIAESFGVKFRVDVERRINGAGAVGAHKTSMLQDLEAGRAMEIDPLLTVVQEMGRLV
HHHHHHHHHCCEEEEEHHHHCCCCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHH
GHPTPMCDAVLGLIKQRDEMARLAA
CCCCHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MKVCIYGAGAIGGYVGAQLARAGAEVSFVARGPHLAAMKANGVRLLIDGEERVARVNCTS
CEEEEEECCHHHHHHHHHHHHCCCCEEEEECCCEEEEEECCCEEEEEECCCCEEEEECCC
DPRELGPQDYVFITLKAHSVPGVVDLMQPLLGPQTAVVTGVNGIPYWYFYKHGGELAGST
CHHHCCCCCEEEEEEEECCCCCHHHHHHHHCCCCCEEEECCCCCCEEEEEECCCCCCCCH
LESVDPGGKQWRGFGPERAIGCVVYPAAEIIEPGVIKHVYGKKFPLGEPDGSQSDRVTRL
HHHCCCCCCCCCCCCCCCCEEEEEECHHHHHCCCHHHHHCCCCCCCCCCCCCCHHHHHHH
SEMMMAADLEAPVRENIRDEIWLKLWGNLCFNPISALTHATLDVITANPATRALSRQMML
HHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCHHHHHHHHHHHH
EAQSIAESFGVKFRVDVERRINGAGAVGAHKTSMLQDLEAGRAMEIDPLLTVVQEMGRLV
HHHHHHHHHCCEEEEEHHHHCCCCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHH
GHPTPMCDAVLGLIKQRDEMARLAA
CCCCHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11214968 [H]