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The map label for this gene is oxlT [H]

Identifier: 73538479

GI number: 73538479

Start: 1342823

End: 1344142

Strand: Reverse

Name: oxlT [H]

Synonym: Reut_B4653

Alternate gene names: 73538479

Gene position: 1344142-1342823 (Counterclockwise)

Preceding gene: 73538480

Following gene: 73538478

Centisome position: 49.31

GC content: 64.32

Gene sequence:

>1320_bases
ATGGAACTGCAGCACAAGGAGTCCACGTCGCGCTTTGCGTCGCCGTGGGTACAGCTGGTCTTCGGCGTCATCTGTATGGC
GATGATTGCCAACATGCAGTATGGGTGGACGCTGTTCGTCAACCCGATCGATGAGAAGTACCACTGGGGCCGCACCGCGA
TTCAGGTCGCGTTCACGATCTTCGTCGTGACTGAAACCTGGCTCGTGCCGATCGAAGGCTATCTGGTCGACAAGTACGGC
CCGCGTCCCGTCGTCGTAGGCGGCGGCCTGCTGTGCGCCGTGGCATGGGTGCTGAATTCCATGGCGTCATCGCTGCCGAT
GCTGTACGTTGCGGCGGCCATCGGGGGTGTCGGTGCCGGCGCGGTCTATGGCACCTGCGTGGGCAATGCGCTCAAGTGGT
TCCCAAACCGGCGCGGCCTGGCCGCGGGCATCACGGCGGCGGGCTTCGGTGCGGGTTCCGCCATGACGGTGGTACCGATC
GCCAACATGATCAAGTCATCGGGCTATGAAGCCACGTTCCTGTGGTTCGGGCTGGGCCAGGGCCTGATCGTGTTCCTCCT
CGGCATGGCCCTGTACCCGCCGTCGGCGAAGATCCTGAGCGAGGTCAAGTCCACGCTGAAGGCAGCCGCCACCTACAACG
CCACGCCGCGCCAGGTGCTGAAGTCGCCGATCTTCTGGATCATGTACGCGATGTTCGTGATGATGGCCGCCGGCGGCCTG
ATGGCCACCGCGCAGCTCGGACCGATCGCCAAGGACTTCGGCTTGCATGACTCGCCGGTATCGATCCTCGGCCTGACGCT
GCCCGCACTGACCTTCGCGCTGACCATCGACCGCGTGCTCAACGGCCTGACCCGTCCGTTCTTCGGCTGGATCTCCGACC
ATATCGGCCGCGAGCGCACCATGTTCTTCGCTTTCGCGGTGGAAGCAGTCGGCATCCTGCTGCTGTCGAAATACGGGCAC
AACCCGGTGGCGTTCGTGGTGCTGACCGGCATCGTGTTCTTCGCCTGGGGCGAGATCTACAGCCTGTTCCCGGCGACCTG
CGGCGATACCTTCGGCCCGAAATTCGCTGCCACCAATGCCGGCTTGCTCTACACCGCCAAGGGCACGGCCGCGCTGCTGG
TACCGTTCTCGAGCGTGATCACCGCCGCGACCGGCGACTGGCATGCGGTGTTCGTGCTGGCCTCGGCCATGGCCGGACTG
TCCGCGCTGCTTGCACTCTTTGTGCTCAAGCCGATGCGTGAAGCGCATGCCCGCAAGTATGTGCATGCCAATACCACCAG
CCCGATGGGATACCGCGCCGTGCCGGAGGACCTGACCTGA

Upstream 100 bases:

>100_bases
GAACGGCTCAGCTGTTCGAGAAAGCGCAGTAAGCGAGAGGCGTCAGCAGGCGCCCGCATCTTCCACCACGGGTGGTTTCG
ACCGCCTAGAAGGAGACATC

Downstream 100 bases:

>100_bases
TCTGATGCAACGATGAAGAGAGCCGTACGGCGTGGCGCTGTCATCACGCAGCACAGACAGCGCAGCCGGTAGCACAATAC
GAGGAAGACAAGAATGAGAG

Product: major facilitator transporter

Products: NA

Alternate protein names: OFA; Oxalate:formate antiport protein; Oxalate:formate exchange protein [H]

Number of amino acids: Translated: 439; Mature: 439

Protein sequence:

>439_residues
MELQHKESTSRFASPWVQLVFGVICMAMIANMQYGWTLFVNPIDEKYHWGRTAIQVAFTIFVVTETWLVPIEGYLVDKYG
PRPVVVGGGLLCAVAWVLNSMASSLPMLYVAAAIGGVGAGAVYGTCVGNALKWFPNRRGLAAGITAAGFGAGSAMTVVPI
ANMIKSSGYEATFLWFGLGQGLIVFLLGMALYPPSAKILSEVKSTLKAAATYNATPRQVLKSPIFWIMYAMFVMMAAGGL
MATAQLGPIAKDFGLHDSPVSILGLTLPALTFALTIDRVLNGLTRPFFGWISDHIGRERTMFFAFAVEAVGILLLSKYGH
NPVAFVVLTGIVFFAWGEIYSLFPATCGDTFGPKFAATNAGLLYTAKGTAALLVPFSSVITAATGDWHAVFVLASAMAGL
SALLALFVLKPMREAHARKYVHANTTSPMGYRAVPEDLT

Sequences:

>Translated_439_residues
MELQHKESTSRFASPWVQLVFGVICMAMIANMQYGWTLFVNPIDEKYHWGRTAIQVAFTIFVVTETWLVPIEGYLVDKYG
PRPVVVGGGLLCAVAWVLNSMASSLPMLYVAAAIGGVGAGAVYGTCVGNALKWFPNRRGLAAGITAAGFGAGSAMTVVPI
ANMIKSSGYEATFLWFGLGQGLIVFLLGMALYPPSAKILSEVKSTLKAAATYNATPRQVLKSPIFWIMYAMFVMMAAGGL
MATAQLGPIAKDFGLHDSPVSILGLTLPALTFALTIDRVLNGLTRPFFGWISDHIGRERTMFFAFAVEAVGILLLSKYGH
NPVAFVVLTGIVFFAWGEIYSLFPATCGDTFGPKFAATNAGLLYTAKGTAALLVPFSSVITAATGDWHAVFVLASAMAGL
SALLALFVLKPMREAHARKYVHANTTSPMGYRAVPEDLT
>Mature_439_residues
MELQHKESTSRFASPWVQLVFGVICMAMIANMQYGWTLFVNPIDEKYHWGRTAIQVAFTIFVVTETWLVPIEGYLVDKYG
PRPVVVGGGLLCAVAWVLNSMASSLPMLYVAAAIGGVGAGAVYGTCVGNALKWFPNRRGLAAGITAAGFGAGSAMTVVPI
ANMIKSSGYEATFLWFGLGQGLIVFLLGMALYPPSAKILSEVKSTLKAAATYNATPRQVLKSPIFWIMYAMFVMMAAGGL
MATAQLGPIAKDFGLHDSPVSILGLTLPALTFALTIDRVLNGLTRPFFGWISDHIGRERTMFFAFAVEAVGILLLSKYGH
NPVAFVVLTGIVFFAWGEIYSLFPATCGDTFGPKFAATNAGLLYTAKGTAALLVPFSSVITAATGDWHAVFVLASAMAGL
SALLALFVLKPMREAHARKYVHANTTSPMGYRAVPEDLT

Specific function: Anion transporter that carries out the exchange of divalent oxalate with monovalent formate, the product of oxalate decarboxylation, at the plasma membrane, and in doing so catalyzes the vectorial portion of a proton-motive metabolic cycle that drives ATP

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. OFA (TC 2.A.1.11) family [H]

Homologues:

Organism=Homo sapiens, GI24431958, Length=436, Percent_Identity=22.9357798165138, Blast_Score=74, Evalue=4e-13,
Organism=Escherichia coli, GI1789969, Length=409, Percent_Identity=25.1833740831296, Blast_Score=103, Evalue=2e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196
- InterPro:   IPR004741 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 46972; Mature: 46972

Theoretical pI: Translated: 9.33; Mature: 9.33

Prosite motif: PS00626 RCC1_2 ; PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MELQHKESTSRFASPWVQLVFGVICMAMIANMQYGWTLFVNPIDEKYHWGRTAIQVAFTI
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCHHCCHHHHHHHHHH
FVVTETWLVPIEGYLVDKYGPRPVVVGGGLLCAVAWVLNSMASSLPMLYVAAAIGGVGAG
HEEHHHEEEEECCEEECCCCCCCEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCH
AVYGTCVGNALKWFPNRRGLAAGITAAGFGAGSAMTVVPIANMIKSSGYEATFLWFGLGQ
HHHHHHHHHHHHHCCCCCCCCCCCHHHCCCCCCCCHHHHHHHHHHCCCCCEEEEEEEHHH
GLIVFLLGMALYPPSAKILSEVKSTLKAAATYNATPRQVLKSPIFWIMYAMFVMMAAGGL
HHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHCHHHHHHHHHHHHHHCCCH
MATAQLGPIAKDFGLHDSPVSILGLTLPALTFALTIDRVLNGLTRPFFGWISDHIGRERT
HHHHHHCCCHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHH
MFFAFAVEAVGILLLSKYGHNPVAFVVLTGIVFFAWGEIYSLFPATCGDTFGPKFAATNA
HHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCHHCCCCCCCCCCCCCC
GLLYTAKGTAALLVPFSSVITAATGDWHAVFVLASAMAGLSALLALFVLKPMREAHARKY
CEEEEECCCEEEEEEHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHE
VHANTTSPMGYRAVPEDLT
EECCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MELQHKESTSRFASPWVQLVFGVICMAMIANMQYGWTLFVNPIDEKYHWGRTAIQVAFTI
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCHHCCHHHHHHHHHH
FVVTETWLVPIEGYLVDKYGPRPVVVGGGLLCAVAWVLNSMASSLPMLYVAAAIGGVGAG
HEEHHHEEEEECCEEECCCCCCCEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCH
AVYGTCVGNALKWFPNRRGLAAGITAAGFGAGSAMTVVPIANMIKSSGYEATFLWFGLGQ
HHHHHHHHHHHHHCCCCCCCCCCCHHHCCCCCCCCHHHHHHHHHHCCCCCEEEEEEEHHH
GLIVFLLGMALYPPSAKILSEVKSTLKAAATYNATPRQVLKSPIFWIMYAMFVMMAAGGL
HHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHCHHHHHHHHHHHHHHCCCH
MATAQLGPIAKDFGLHDSPVSILGLTLPALTFALTIDRVLNGLTRPFFGWISDHIGRERT
HHHHHHCCCHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHH
MFFAFAVEAVGILLLSKYGHNPVAFVVLTGIVFFAWGEIYSLFPATCGDTFGPKFAATNA
HHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCHHCCCCCCCCCCCCCC
GLLYTAKGTAALLVPFSSVITAATGDWHAVFVLASAMAGLSALLALFVLKPMREAHARKY
CEEEEECCCEEEEEEHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHE
VHANTTSPMGYRAVPEDLT
EECCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8636101; 9651403; 11919184; 11113128; 11274108; 11500368 [H]