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The map label for this gene is alsR [H]

Identifier: 73538466

GI number: 73538466

Start: 1325531

End: 1326460

Strand: Reverse

Name: alsR [H]

Synonym: Reut_B4639

Alternate gene names: 73538466

Gene position: 1326460-1325531 (Counterclockwise)

Preceding gene: 73538469

Following gene: 73538465

Centisome position: 48.66

GC content: 67.1

Gene sequence:

>930_bases
ATGATTCCGGATCTGAACCAATTGCGCTGCTTTATCGCCGTGGGCGAGGAGCTGCACTTTGGCCGTGCCGCCACGCGGCT
TTTCATGACGCAATCGCCGCTGAGCCGGCAGATCCGCATGCTGGAGGAATCGCTCGGCGTACGGCTGTTCGACCGCAACA
GCCGCGTGGTACGCCTGACCGCGGCCGGCAGCGCCTTGCTCGACGACGCGCGGCGCCTGCTGGCACTGGCGGGTCACGCG
GTGGACGTGGCGCGGCGGATCGACAAGGGCGTCAGCGGCAAGGTACGCGTCGGCTTCACCGCCGTGGCCGGCTACGAACT
GGTGCCCAACCTGATCGCCCGGGCCATGCAGGAGTTGCCGGAGATCGAGGTGACCCTGCATGAGATGGTGACCGTCGCGC
AGATTGAGGCCTTGCAGGCAGGGACCATCGACCTGGGCTTCCTGCGGCCGCTGCCGGACGTGGATCCGGAGCTGCAATGG
CGGCCCGCGGTCAGTGAGCCGCTGCTGCTTGCCATGCATGCGACACATGCGCTGGCGGCGCGGGAGCGCATCGCCGCCGA
AGATCTGGCGGGCCAGACATTCATCCAGTACTCCGCCACCGAAGGCAAATATTTCCATGATCTGATCGGCTCGGTGCTCG
CCGGCGCCGGCCGTCCGCCACGTGTGGTGCAGCAGATGAGCCAGACGCATAGCGTGCTCGCGCTGGTGCGCGCTGGACTG
GGGCTGGCGCTGGTGCCGGCATCGGCGCGGCATCTGCATTTCCCGGGCGTCGTGTTGCGGCCGATCTGGCGCGACGATGT
GCGAGCGGAACTGCGGTTGGTGTGGCGCGATGCGAACCGCAACCCGGCGTGCCGGGTGTTTGCGGATTTTGCGGCGATGC
ATCTTGCAAGCGCGAAGGAGCTCAGCCAGACGTTGACAGCCTCGGACTGA

Upstream 100 bases:

>100_bases
GCGTCTTGGAGCGGTTGTCGATGGGCCGAGTATAGGAACGCCATCCATGCATGTCTAAGCTATAGTTTGCATCGATCAAT
CCAACTATTGGCATGATGCA

Downstream 100 bases:

>100_bases
GGTGCCTCGCGGTGTCTACCATTCTTCAATCGATGCGGTGGTTCTTACACGCCGCATCGACGGGTGTGCGGTTTGTGTGA
CGTGACATGCTGGAACGAAA

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: Als operon regulatory protein [H]

Number of amino acids: Translated: 309; Mature: 309

Protein sequence:

>309_residues
MIPDLNQLRCFIAVGEELHFGRAATRLFMTQSPLSRQIRMLEESLGVRLFDRNSRVVRLTAAGSALLDDARRLLALAGHA
VDVARRIDKGVSGKVRVGFTAVAGYELVPNLIARAMQELPEIEVTLHEMVTVAQIEALQAGTIDLGFLRPLPDVDPELQW
RPAVSEPLLLAMHATHALAARERIAAEDLAGQTFIQYSATEGKYFHDLIGSVLAGAGRPPRVVQQMSQTHSVLALVRAGL
GLALVPASARHLHFPGVVLRPIWRDDVRAELRLVWRDANRNPACRVFADFAAMHLASAKELSQTLTASD

Sequences:

>Translated_309_residues
MIPDLNQLRCFIAVGEELHFGRAATRLFMTQSPLSRQIRMLEESLGVRLFDRNSRVVRLTAAGSALLDDARRLLALAGHA
VDVARRIDKGVSGKVRVGFTAVAGYELVPNLIARAMQELPEIEVTLHEMVTVAQIEALQAGTIDLGFLRPLPDVDPELQW
RPAVSEPLLLAMHATHALAARERIAAEDLAGQTFIQYSATEGKYFHDLIGSVLAGAGRPPRVVQQMSQTHSVLALVRAGL
GLALVPASARHLHFPGVVLRPIWRDDVRAELRLVWRDANRNPACRVFADFAAMHLASAKELSQTLTASD
>Mature_309_residues
MIPDLNQLRCFIAVGEELHFGRAATRLFMTQSPLSRQIRMLEESLGVRLFDRNSRVVRLTAAGSALLDDARRLLALAGHA
VDVARRIDKGVSGKVRVGFTAVAGYELVPNLIARAMQELPEIEVTLHEMVTVAQIEALQAGTIDLGFLRPLPDVDPELQW
RPAVSEPLLLAMHATHALAARERIAAEDLAGQTFIQYSATEGKYFHDLIGSVLAGAGRPPRVVQQMSQTHSVLALVRAGL
GLALVPASARHLHFPGVVLRPIWRDDVRAELRLVWRDANRNPACRVFADFAAMHLASAKELSQTLTASD

Specific function: Regulates the expression of the alsSD operon for acetoin biosynthesis [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1787879, Length=288, Percent_Identity=35.4166666666667, Blast_Score=168, Evalue=5e-43,
Organism=Escherichia coli, GI2367136, Length=292, Percent_Identity=31.8493150684932, Blast_Score=146, Evalue=2e-36,
Organism=Escherichia coli, GI1788887, Length=294, Percent_Identity=31.6326530612245, Blast_Score=138, Evalue=6e-34,
Organism=Escherichia coli, GI1788748, Length=249, Percent_Identity=31.7269076305221, Blast_Score=117, Evalue=8e-28,
Organism=Escherichia coli, GI1790399, Length=278, Percent_Identity=30.5755395683453, Blast_Score=113, Evalue=2e-26,
Organism=Escherichia coli, GI145693105, Length=292, Percent_Identity=28.7671232876712, Blast_Score=102, Evalue=3e-23,
Organism=Escherichia coli, GI157672245, Length=242, Percent_Identity=32.2314049586777, Blast_Score=95, Evalue=6e-21,
Organism=Escherichia coli, GI1790262, Length=226, Percent_Identity=28.7610619469027, Blast_Score=78, Evalue=7e-16,
Organism=Escherichia coli, GI1787530, Length=247, Percent_Identity=24.2914979757085, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1787806, Length=250, Percent_Identity=27.6, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1787601, Length=289, Percent_Identity=26.643598615917, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI1790208, Length=149, Percent_Identity=33.5570469798658, Blast_Score=72, Evalue=4e-14,
Organism=Escherichia coli, GI1786713, Length=94, Percent_Identity=41.4893617021277, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI48994962, Length=72, Percent_Identity=48.6111111111111, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI87081904, Length=154, Percent_Identity=31.8181818181818, Blast_Score=66, Evalue=2e-12,
Organism=Escherichia coli, GI1788626, Length=243, Percent_Identity=27.1604938271605, Blast_Score=65, Evalue=6e-12,
Organism=Escherichia coli, GI1788296, Length=234, Percent_Identity=26.4957264957265, Blast_Score=62, Evalue=4e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 33860; Mature: 33860

Theoretical pI: Translated: 8.29; Mature: 8.29

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIPDLNQLRCFIAVGEELHFGRAATRLFMTQSPLSRQIRMLEESLGVRLFDRNSRVVRLT
CCCCHHHHEEEEEECCHHHCCHHHHHHHHCCCHHHHHHHHHHHHHCEEEEECCCCEEEEE
AAGSALLDDARRLLALAGHAVDVARRIDKGVSGKVRVGFTAVAGYELVPNLIARAMQELP
ECCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEEHHHHHHHHHHHHHHHHHCC
EIEVTLHEMVTVAQIEALQAGTIDLGFLRPLPDVDPELQWRPAVSEPLLLAMHATHALAA
CHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCCCCCCCEECCCCCCCHHHHHHHHHHHHH
RERIAAEDLAGQTFIQYSATEGKYFHDLIGSVLAGAGRPPRVVQQMSQTHSVLALVRAGL
HHHHHHHHHCCCEEEEEECCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCC
GLALVPASARHLHFPGVVLRPIWRDDVRAELRLVWRDANRNPACRVFADFAAMHLASAKE
CEEEECCCCCEEECCCCEECCCCHHHHHHHHEEEEECCCCCCHHHHHHHHHHHHHHHHHH
LSQTLTASD
HHHHHCCCC
>Mature Secondary Structure
MIPDLNQLRCFIAVGEELHFGRAATRLFMTQSPLSRQIRMLEESLGVRLFDRNSRVVRLT
CCCCHHHHEEEEEECCHHHCCHHHHHHHHCCCHHHHHHHHHHHHHCEEEEECCCCEEEEE
AAGSALLDDARRLLALAGHAVDVARRIDKGVSGKVRVGFTAVAGYELVPNLIARAMQELP
ECCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEEHHHHHHHHHHHHHHHHHCC
EIEVTLHEMVTVAQIEALQAGTIDLGFLRPLPDVDPELQWRPAVSEPLLLAMHATHALAA
CHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCCCCCCCEECCCCCCCHHHHHHHHHHHHH
RERIAAEDLAGQTFIQYSATEGKYFHDLIGSVLAGAGRPPRVVQQMSQTHSVLALVRAGL
HHHHHHHHHCCCEEEEEECCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCC
GLALVPASARHLHFPGVVLRPIWRDDVRAELRLVWRDANRNPACRVFADFAAMHLASAKE
CEEEECCCCCEEECCCCEECCCCHHHHHHHHEEEEECCCCCCHHHHHHHHHHHHHHHHHH
LSQTLTASD
HHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7685336; 9353933; 9384377 [H]