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The map label for this gene is celR [H]

Identifier: 73538355

GI number: 73538355

Start: 1200487

End: 1201569

Strand: Direct

Name: celR [H]

Synonym: Reut_B4528

Alternate gene names: 73538355

Gene position: 1200487-1201569 (Clockwise)

Preceding gene: 73538353

Following gene: 73538359

Centisome position: 44.04

GC content: 67.5

Gene sequence:

>1083_bases
TTGTATCCTCCCGGCACTGCTTCCCGAAATGGCATGTCCGACTCCATCCGCCCCCCTCCATCCGAACGCACCGGCAAACC
GCGCCGCATCACCATTCATGACGTGGCACGCGCGGCCGGGGTGTCGCTGACGACCGTATCGCATTCACTGAATGACCGTG
GCGTCGTAGATCCCGCCACGCGGGCGCGTGTAAAGCGCATCGCGGCAGAACTCGGCTACCGGCCCAGCGTGCGTGCGCAG
CGCCTGCAGTCCGGCCGCGCGAACTGCATTGCGCTGCTGTCATCGATGCCGTTCGCGGTGGCAGGCGGCACGTCGCGGCT
CGGATTCATGATGGAAGTCGCAGCCATTGCCGCGGAAGCCGCCATGGCGCGCGGGCTCGGCGTCGTGCTGGTGCCGCCGC
TGGAAGGCGCCGGGGGCTTGCTGGAAACGCTCGACATCGATGGTGCGATCGTGATCGAGCCACTGGCCGGCGACCCGCAT
ATCGCACGCCTGCGCGAGCGCGGTGTGAGCATCGTGTCGATCGGCCGCGAACCGCTTACCGACAGCCCGGTGCCCTACGT
GGACCTGCAATCGGCAGACACCGCGCGCATGCTGCTGGAACACTTGCATACGCACGGCCGTAAGCAGATTGGCCTGATGA
TCGGCGACGCTGCGAGGCAATCATATGTGGAAACCGAGCGCGTCTACCGCGAATTCACGCAAGCGAACGGGCTGCCCTGC
ACACTGGTCAAGGCGCCCGAGGCGCAAGGCGAAGCTGCCGGTGCCGAGGCCTGCGCGCAGTTGCTGGCACAGCTGCCCAG
TCTCGATGCACTGTGCGCGCCCGTGGACGCCTTCGCCGTGGGCGCGATGGAGCATCTGAACAAGTCCGGCAAGCGCGTGC
CGGACGATGTGCAGGTCGTGACACGCTACGACGGCATCCGCGCGCGTACCGCGCACCCGCCGCTCACCGCCGTCAATCTG
CACCTCGAGCGCGTCGCCGCGCTGGCCGTGGATCTGCTGTTTGCGCACCTGTCCGGCGATCGCAGCCGGCAAACCGTGGT
GGGCCCGGCGCCGGAGCTCATTGTGCGCGCATCGTCAGCCTAA

Upstream 100 bases:

>100_bases
AGATAGACGAGTCGATGTTCCATGTCGGATCTGGTCAGGGCTGTCATTTCATTCGCACGCGAATGTTATCACGCGGCCCT
GTGCCGGGATTCTGCCCCTG

Downstream 100 bases:

>100_bases
CCGCGCAGCAGGACGACCGCGCCCGAAACCAGCGCGAACGCCAGCACGCCCACGCGCAGCATGCGCTGGTTGATGCGCCG
ATGGACGAGGTGGCTCGCCA

Product: LacI family transcription regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 360; Mature: 360

Protein sequence:

>360_residues
MYPPGTASRNGMSDSIRPPPSERTGKPRRITIHDVARAAGVSLTTVSHSLNDRGVVDPATRARVKRIAAELGYRPSVRAQ
RLQSGRANCIALLSSMPFAVAGGTSRLGFMMEVAAIAAEAAMARGLGVVLVPPLEGAGGLLETLDIDGAIVIEPLAGDPH
IARLRERGVSIVSIGREPLTDSPVPYVDLQSADTARMLLEHLHTHGRKQIGLMIGDAARQSYVETERVYREFTQANGLPC
TLVKAPEAQGEAAGAEACAQLLAQLPSLDALCAPVDAFAVGAMEHLNKSGKRVPDDVQVVTRYDGIRARTAHPPLTAVNL
HLERVAALAVDLLFAHLSGDRSRQTVVGPAPELIVRASSA

Sequences:

>Translated_360_residues
MYPPGTASRNGMSDSIRPPPSERTGKPRRITIHDVARAAGVSLTTVSHSLNDRGVVDPATRARVKRIAAELGYRPSVRAQ
RLQSGRANCIALLSSMPFAVAGGTSRLGFMMEVAAIAAEAAMARGLGVVLVPPLEGAGGLLETLDIDGAIVIEPLAGDPH
IARLRERGVSIVSIGREPLTDSPVPYVDLQSADTARMLLEHLHTHGRKQIGLMIGDAARQSYVETERVYREFTQANGLPC
TLVKAPEAQGEAAGAEACAQLLAQLPSLDALCAPVDAFAVGAMEHLNKSGKRVPDDVQVVTRYDGIRARTAHPPLTAVNL
HLERVAALAVDLLFAHLSGDRSRQTVVGPAPELIVRASSA
>Mature_360_residues
MYPPGTASRNGMSDSIRPPPSERTGKPRRITIHDVARAAGVSLTTVSHSLNDRGVVDPATRARVKRIAAELGYRPSVRAQ
RLQSGRANCIALLSSMPFAVAGGTSRLGFMMEVAAIAAEAAMARGLGVVLVPPLEGAGGLLETLDIDGAIVIEPLAGDPH
IARLRERGVSIVSIGREPLTDSPVPYVDLQSADTARMLLEHLHTHGRKQIGLMIGDAARQSYVETERVYREFTQANGLPC
TLVKAPEAQGEAAGAEACAQLLAQLPSLDALCAPVDAFAVGAMEHLNKSGKRVPDDVQVVTRYDGIRARTAHPPLTAVNL
HLERVAALAVDLLFAHLSGDRSRQTVVGPAPELIVRASSA

Specific function: Binds to the 14-bp operator sequence 5'-TGGGAGCGCTCCCA- 3' in the upstream regions of cellulase genes; these operator sequences are modulated by cellobiose [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lacI-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1787948, Length=345, Percent_Identity=26.9565217391304, Blast_Score=78, Evalue=7e-16,
Organism=Escherichia coli, GI1787906, Length=280, Percent_Identity=29.2857142857143, Blast_Score=76, Evalue=3e-15,
Organism=Escherichia coli, GI1786540, Length=319, Percent_Identity=25.705329153605, Blast_Score=68, Evalue=7e-13,
Organism=Escherichia coli, GI1787580, Length=327, Percent_Identity=24.1590214067278, Blast_Score=63, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000843
- InterPro:   IPR010982
- InterPro:   IPR001761 [H]

Pfam domain/function: PF00356 LacI; PF00532 Peripla_BP_1 [H]

EC number: NA

Molecular weight: Translated: 38068; Mature: 38068

Theoretical pI: Translated: 8.35; Mature: 8.35

Prosite motif: PS50932 HTH_LACI_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYPPGTASRNGMSDSIRPPPSERTGKPRRITIHDVARAAGVSLTTVSHSLNDRGVVDPAT
CCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEHHHHHHHHCCEEEEEECCCCCCCCCCHHH
RARVKRIAAELGYRPSVRAQRLQSGRANCIALLSSMPFAVAGGTSRLGFMMEVAAIAAEA
HHHHHHHHHHHCCCCCHHHHHHHCCCHHHHHHHHCCCEEEECCCHHHHHHHHHHHHHHHH
AMARGLGVVLVPPLEGAGGLLETLDIDGAIVIEPLAGDPHIARLRERGVSIVSIGREPLT
HHHCCCCEEEECCCCCCCCCEEEECCCCEEEEEECCCCHHHHHHHHCCCEEEEECCCCCC
DSPVPYVDLQSADTARMLLEHLHTHGRKQIGLMIGDAARQSYVETERVYREFTQANGLPC
CCCCCEEECCCCCHHHHHHHHHHHCCCCEEEEEECHHHHHHHHHHHHHHHHHHHCCCCCE
TLVKAPEAQGEAAGAEACAQLLAQLPSLDALCAPVDAFAVGAMEHLNKSGKRVPDDVQVV
EEEECCCCCCCCCCHHHHHHHHHHCCCCHHHHCCHHHHHHHHHHHHHHCCCCCCCHHHHH
TRYDGIRARTAHPPLTAVNLHLERVAALAVDLLFAHLSGDRSRQTVVGPAPELIVRASSA
HHCCCCEEECCCCCCEEEHHHHHHHHHHHHHHHHHHHCCCCCCCEEECCCHHHEEEECCC
>Mature Secondary Structure
MYPPGTASRNGMSDSIRPPPSERTGKPRRITIHDVARAAGVSLTTVSHSLNDRGVVDPAT
CCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEHHHHHHHHCCEEEEEECCCCCCCCCCHHH
RARVKRIAAELGYRPSVRAQRLQSGRANCIALLSSMPFAVAGGTSRLGFMMEVAAIAAEA
HHHHHHHHHHHCCCCCHHHHHHHCCCHHHHHHHHCCCEEEECCCHHHHHHHHHHHHHHHH
AMARGLGVVLVPPLEGAGGLLETLDIDGAIVIEPLAGDPHIARLRERGVSIVSIGREPLT
HHHCCCCEEEECCCCCCCCCEEEECCCCEEEEEECCCCHHHHHHHHCCCEEEEECCCCCC
DSPVPYVDLQSADTARMLLEHLHTHGRKQIGLMIGDAARQSYVETERVYREFTQANGLPC
CCCCCEEECCCCCHHHHHHHHHHHCCCCEEEEEECHHHHHHHHHHHHHHHHHHHCCCCCE
TLVKAPEAQGEAAGAEACAQLLAQLPSLDALCAPVDAFAVGAMEHLNKSGKRVPDDVQVV
EEEECCCCCCCCCCHHHHHHHHHHCCCCHHHHCCHHHHHHHHHHHHHHCCCCCCCHHHHH
TRYDGIRARTAHPPLTAVNLHLERVAALAVDLLFAHLSGDRSRQTVVGPAPELIVRASSA
HHCCCCEEECCCCCCEEEHHHHHHHHHHHHHHHHHHHCCCCCCCEEECCCHHHEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10224066 [H]