Click here to switch to the map view.

The map label for this gene is bepF [H]

Identifier: 73538165

GI number: 73538165

Start: 994673

End: 995905

Strand: Reverse

Name: bepF [H]

Synonym: Reut_B4335

Alternate gene names: 73538165

Gene position: 995905-994673 (Counterclockwise)

Preceding gene: 73538166

Following gene: 73538164

Centisome position: 36.53

GC content: 66.1

Gene sequence:

>1233_bases
ATGAGTACCCTGAATCGACGCACGTTGATCGCGATTGCCATCGTGGTCGTCCTCGGCGCCGGCGTTGCCACCTCCATGCT
GCAGCCATGGCATGGCGGCGAGGCGCATGCCAACACGCCGCCGCCGGCTCCGACTATTGAAGTGGCAAACGTGGTCGGCA
AGACCATTACCGAATGGGACGAGTTCTCGGGCCGTATCGAAGCCGTGGACCGCGTGGAAATCCGCCCGCGCGTTTCCGGC
ACGATTGAAACGGTGCATTTCCGCGAAGGCTCGATCGTGAAGAAGGGCGATCCGCTGTTCACGATCGATCCGCGTCCGTA
CGCGGCTGAAGTGGCGCGCGCCGAGGCAGCGCTGGCCGCGGCTCAGGTGCGCGCCTCGCACGCGCAGACCGAGAAGGCGC
GCGCCCAGCGCCTGCTGGACGACAACGCCATCTCGAAGCGCGAATTTGACGAGCGCATCAACGCCGCCAGCGAACTGTCC
GCCGACGTGCGCGGCGCGCAGGCGGCGCTAGAGGTGGCGAAGCTGAACCTGAGCTATACGCGCATCGTTGCGCCGGTATC
GGGCAAGGTATCGCGTGCGGAAATCACGGTAGGCAACCTTGTCGCAGCGGGCGCCGCATCGCCGCCGCTGACGTCGGTGG
TGTCGGTCTCACCGGTGTATGCAAGTTTCGATGTCGACGAGCAGAGCTACCTGCGCTATACCGCGCCCGGTGCCGGCGGC
GGCAAGAACGGCCTGCCGGTGTTCCTGGGCCTGGCTAACGAGGACGGCAATCCGCACGAGGGCAAGATCCACTCGATCGA
CAACCGGCTCGATACGCGCAGCGGCACCATCCGCGTGCGCGCGGTGTTCGACAACGAGGATGGCCGCCTGTTGCCGGGCC
TGTATGCGAAGGTCAAGCTTGGGGGCGGTTCGCCGCACGACGCCGTGCTGATCAACGACCGCGCGATCGGCACTGACCAG
GGCAAGAAGTTCGTGCTCGTGGTCGATAAGGCCAACAAGCTGACCTATCGCGAAGTCGACCTCGGGCCGACCTTTGAAGG
GCTGCGCGTGATCCGCAAGGGTTTGAAGCCCGGCGAGAGCATCGTCGTGAACGGCCTGCAGCGTGTGCGCCCCGGCGATA
CGGTGGCACCGAAGCCCGTCTCGATGGCGTTCCGCAGCGAACTGGAGCCACGCCCCAACGCGCCTGACCGCAAGCAGGCG
GCCGCCGAGGCCGAAGGCAAGCCCGTCAGCTAA

Upstream 100 bases:

>100_bases
AAGCTCCGGACCGCATTCCGCGGCCCGGCCGGCGGCGTTCGTGCTTTCGCAGCCTTTTGCTTTTCCAGTTGAAGAAAACC
CGCAACAGGAGTGAAGAGAA

Downstream 100 bases:

>100_bases
GCAGGCAGACAAGCCCCAACACAGACAGTCAGGCGCTTTGCTTCCCCGCATGTGCATGGCGCCCGCCACGGCGGGCCGCC
AGGGGGGCTTGCATGCCGAA

Product: secretion protein HlyD

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 410; Mature: 409

Protein sequence:

>410_residues
MSTLNRRTLIAIAIVVVLGAGVATSMLQPWHGGEAHANTPPPAPTIEVANVVGKTITEWDEFSGRIEAVDRVEIRPRVSG
TIETVHFREGSIVKKGDPLFTIDPRPYAAEVARAEAALAAAQVRASHAQTEKARAQRLLDDNAISKREFDERINAASELS
ADVRGAQAALEVAKLNLSYTRIVAPVSGKVSRAEITVGNLVAAGAASPPLTSVVSVSPVYASFDVDEQSYLRYTAPGAGG
GKNGLPVFLGLANEDGNPHEGKIHSIDNRLDTRSGTIRVRAVFDNEDGRLLPGLYAKVKLGGGSPHDAVLINDRAIGTDQ
GKKFVLVVDKANKLTYREVDLGPTFEGLRVIRKGLKPGESIVVNGLQRVRPGDTVAPKPVSMAFRSELEPRPNAPDRKQA
AAEAEGKPVS

Sequences:

>Translated_410_residues
MSTLNRRTLIAIAIVVVLGAGVATSMLQPWHGGEAHANTPPPAPTIEVANVVGKTITEWDEFSGRIEAVDRVEIRPRVSG
TIETVHFREGSIVKKGDPLFTIDPRPYAAEVARAEAALAAAQVRASHAQTEKARAQRLLDDNAISKREFDERINAASELS
ADVRGAQAALEVAKLNLSYTRIVAPVSGKVSRAEITVGNLVAAGAASPPLTSVVSVSPVYASFDVDEQSYLRYTAPGAGG
GKNGLPVFLGLANEDGNPHEGKIHSIDNRLDTRSGTIRVRAVFDNEDGRLLPGLYAKVKLGGGSPHDAVLINDRAIGTDQ
GKKFVLVVDKANKLTYREVDLGPTFEGLRVIRKGLKPGESIVVNGLQRVRPGDTVAPKPVSMAFRSELEPRPNAPDRKQA
AAEAEGKPVS
>Mature_409_residues
STLNRRTLIAIAIVVVLGAGVATSMLQPWHGGEAHANTPPPAPTIEVANVVGKTITEWDEFSGRIEAVDRVEIRPRVSGT
IETVHFREGSIVKKGDPLFTIDPRPYAAEVARAEAALAAAQVRASHAQTEKARAQRLLDDNAISKREFDERINAASELSA
DVRGAQAALEVAKLNLSYTRIVAPVSGKVSRAEITVGNLVAAGAASPPLTSVVSVSPVYASFDVDEQSYLRYTAPGAGGG
KNGLPVFLGLANEDGNPHEGKIHSIDNRLDTRSGTIRVRAVFDNEDGRLLPGLYAKVKLGGGSPHDAVLINDRAIGTDQG
KKFVLVVDKANKLTYREVDLGPTFEGLRVIRKGLKPGESIVVNGLQRVRPGDTVAPKPVSMAFRSELEPRPNAPDRKQAA
AEAEGKPVS

Specific function: May contribute to resistance to some drugs, such as deoxycholate, sodium dodecyl sulfate and nalidixic acid, in the absence of BepD and BepE [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Periplasm (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family [H]

Homologues:

Organism=Escherichia coli, GI1789929, Length=374, Percent_Identity=31.8181818181818, Blast_Score=177, Evalue=1e-45,
Organism=Escherichia coli, GI1786668, Length=384, Percent_Identity=32.5520833333333, Blast_Score=166, Evalue=3e-42,
Organism=Escherichia coli, GI1789665, Length=348, Percent_Identity=31.3218390804598, Blast_Score=155, Evalue=6e-39,
Organism=Escherichia coli, GI87082036, Length=346, Percent_Identity=29.1907514450867, Blast_Score=151, Evalue=8e-38,
Organism=Escherichia coli, GI87081796, Length=381, Percent_Identity=25.1968503937008, Blast_Score=91, Evalue=2e-19,
Organism=Escherichia coli, GI87081951, Length=232, Percent_Identity=31.4655172413793, Blast_Score=81, Evalue=2e-16,
Organism=Escherichia coli, GI1789637, Length=252, Percent_Identity=29.3650793650794, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1790519, Length=251, Percent_Identity=26.2948207171315, Blast_Score=63, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006143 [H]

Pfam domain/function: PF00529 HlyD [H]

EC number: NA

Molecular weight: Translated: 43637; Mature: 43506

Theoretical pI: Translated: 9.44; Mature: 9.44

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
0.7 %Met     (Translated Protein)
0.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.5 %Met     (Mature Protein)
0.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTLNRRTLIAIAIVVVLGAGVATSMLQPWHGGEAHANTPPPAPTIEVANVVGKTITEWD
CCCCCHHHHHHHHHHHHHCCCHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHH
EFSGRIEAVDRVEIRPRVSGTIETVHFREGSIVKKGDPLFTIDPRPYAAEVARAEAALAA
HHCCCEEEEEEEEECCCCCCEEEEEEECCCCEEECCCCEEEECCCCHHHHHHHHHHHHHH
AQVRASHAQTEKARAQRLLDDNAISKREFDERINAASELSADVRGAQAALEVAKLNLSYT
HHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHCCCEEE
RIVAPVSGKVSRAEITVGNLVAAGAASPPLTSVVSVSPVYASFDVDEQSYLRYTAPGAGG
EEEECCCCCCEEEEEEECCEEECCCCCCCCHHHEEECCEEEEECCCCCCEEEEECCCCCC
GKNGLPVFLGLANEDGNPHEGKIHSIDNRLDTRSGTIRVRAVFDNEDGRLLPGLYAKVKL
CCCCCEEEEEEECCCCCCCCCCEEECCCCCCCCCCEEEEEEEEECCCCCCCCCEEEEEEE
GGGSPHDAVLINDRAIGTDQGKKFVLVVDKANKLTYREVDLGPTFEGLRVIRKGLKPGES
CCCCCCCEEEEECCCCCCCCCCEEEEEEECCCCEEEEEECCCCCHHHHHHHHHHCCCCHH
IVVNGLQRVRPGDTVAPKPVSMAFRSELEPRPNAPDRKQAAAEAEGKPVS
HHHHHHHHCCCCCCCCCCCHHHHHHHCCCCCCCCCCHHHHHHHCCCCCCC
>Mature Secondary Structure 
STLNRRTLIAIAIVVVLGAGVATSMLQPWHGGEAHANTPPPAPTIEVANVVGKTITEWD
CCCCHHHHHHHHHHHHHCCCHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHH
EFSGRIEAVDRVEIRPRVSGTIETVHFREGSIVKKGDPLFTIDPRPYAAEVARAEAALAA
HHCCCEEEEEEEEECCCCCCEEEEEEECCCCEEECCCCEEEECCCCHHHHHHHHHHHHHH
AQVRASHAQTEKARAQRLLDDNAISKREFDERINAASELSADVRGAQAALEVAKLNLSYT
HHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHCCCEEE
RIVAPVSGKVSRAEITVGNLVAAGAASPPLTSVVSVSPVYASFDVDEQSYLRYTAPGAGG
EEEECCCCCCEEEEEEECCEEECCCCCCCCHHHEEECCEEEEECCCCCCEEEEECCCCCC
GKNGLPVFLGLANEDGNPHEGKIHSIDNRLDTRSGTIRVRAVFDNEDGRLLPGLYAKVKL
CCCCCEEEEEEECCCCCCCCCCEEECCCCCCCCCCEEEEEEEEECCCCCCCCCEEEEEEE
GGGSPHDAVLINDRAIGTDQGKKFVLVVDKANKLTYREVDLGPTFEGLRVIRKGLKPGES
CCCCCCCEEEEECCCCCCCCCCEEEEEEECCCCEEEEEECCCCCHHHHHHHHHHCCCCHH
IVVNGLQRVRPGDTVAPKPVSMAFRSELEPRPNAPDRKQAAAEAEGKPVS
HHHHHHHHCCCCCCCCCCCHHHHHHHCCCCCCCCCCHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12271122 [H]