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The map label for this gene is btr [H]

Identifier: 73538042

GI number: 73538042

Start: 851696

End: 852607

Strand: Reverse

Name: btr [H]

Synonym: Reut_B4212

Alternate gene names: 73538042

Gene position: 852607-851696 (Counterclockwise)

Preceding gene: 73538045

Following gene: 73538041

Centisome position: 31.28

GC content: 67.32

Gene sequence:

>912_bases
ATGTTGCTGACCACCCGCCCACCATCGCCCGATTCGATCCCGTGCTGCGCCGGATGCTCCATGGCACGTGTTTGCCTGGC
CGGGAACTGCGATTCCGACGGCGAGGGACCGGCGGACGGACTGGCCCAGCGCGTGATCCGCCTGCGCAAGGGCGAACCGC
TCTACCTGCTGGGCGATCCGCTCGCCGCGCTGTTCGCCGTCCGCGTGGGGACCGTCAAGACCCACGTAGCCACGGAAGAC
GGGCGCACCCAAGTGGTCGGCTTTCATTTCCCGGGGGAGGTCGTCGGCCTGGACAGCATTGGCCGGCGCCAATACGCGTC
GTATGCCACGGCGCTTGAAGACACCAAGGTCTGCATGATCCCCATGGACGTGCTGCGGCCGCTGGCGGCCTGCACGCCTG
CGCTCGCAAGCCGTGTGTTCCGCGCGCTGGACGGCTACGCGCAACGCACGCGGGCGCTGCAGACCTTGCTTGCGCTGATG
ACCGCGGAAGAACGCCTGGTCACCTTCCTGCTATGGATCTCGGAGGGGTTGGCGGCACGTGGCTTTTCGTCCAGCGAGTT
CATCCTGCGCATGAGCCGCGAGGAAATCGGCAGCTATATCGGCCTGACGCTGGAGACGGTCAGCCGGCAATTTTCGCGGC
TGGCGGAATGCGGGCTGATCCGTGTGAAGCACCGCAGCGTGGCGCTGGTCGACAAGGCCGGGCTGCGCGCCATTGCCGAC
CGTTCCGCGATTTCCCCGATTCCGCCCGGCACCAACCGCCGGCGAGGTGGCGAGCAGCGCGTGCCGGCACAGGCATTGCG
CACGTCGGCACCGGCATGGGCAACGCGGACCCAGCCCGCGACCGCCGCGATGCAGGCAGACAACCCGAAGATAAACCCGT
TTGCATGGGAGGCTGGCAATGGACAGCAATGA

Upstream 100 bases:

>100_bases
TCAAGGTTTTTGTGATTTGGTTTTCCCAGTTAATTTGATTATCTGGAAAAAACCAGCAAATAAACCGTCCAGTGTGAAAC
TCTATGCCGAGCTCCCCATC

Downstream 100 bases:

>100_bases
CCTGGTACGTGAGATCAAGGACGTGAATCTGGCCTATCTGCTGCTGGTGCAGCGCCTGATGCGCCAGAACGAGGCCGAGG
CACTGTTCCGGCTCGGCATC

Product: cyclic nucleotide-binding protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 303; Mature: 303

Protein sequence:

>303_residues
MLLTTRPPSPDSIPCCAGCSMARVCLAGNCDSDGEGPADGLAQRVIRLRKGEPLYLLGDPLAALFAVRVGTVKTHVATED
GRTQVVGFHFPGEVVGLDSIGRRQYASYATALEDTKVCMIPMDVLRPLAACTPALASRVFRALDGYAQRTRALQTLLALM
TAEERLVTFLLWISEGLAARGFSSSEFILRMSREEIGSYIGLTLETVSRQFSRLAECGLIRVKHRSVALVDKAGLRAIAD
RSAISPIPPGTNRRRGGEQRVPAQALRTSAPAWATRTQPATAAMQADNPKINPFAWEAGNGQQ

Sequences:

>Translated_303_residues
MLLTTRPPSPDSIPCCAGCSMARVCLAGNCDSDGEGPADGLAQRVIRLRKGEPLYLLGDPLAALFAVRVGTVKTHVATED
GRTQVVGFHFPGEVVGLDSIGRRQYASYATALEDTKVCMIPMDVLRPLAACTPALASRVFRALDGYAQRTRALQTLLALM
TAEERLVTFLLWISEGLAARGFSSSEFILRMSREEIGSYIGLTLETVSRQFSRLAECGLIRVKHRSVALVDKAGLRAIAD
RSAISPIPPGTNRRRGGEQRVPAQALRTSAPAWATRTQPATAAMQADNPKINPFAWEAGNGQQ
>Mature_303_residues
MLLTTRPPSPDSIPCCAGCSMARVCLAGNCDSDGEGPADGLAQRVIRLRKGEPLYLLGDPLAALFAVRVGTVKTHVATED
GRTQVVGFHFPGEVVGLDSIGRRQYASYATALEDTKVCMIPMDVLRPLAACTPALASRVFRALDGYAQRTRALQTLLALM
TAEERLVTFLLWISEGLAARGFSSSEFILRMSREEIGSYIGLTLETVSRQFSRLAECGLIRVKHRSVALVDKAGLRAIAD
RSAISPIPPGTNRRRGGEQRVPAQALRTSAPAWATRTQPATAAMQADNPKINPFAWEAGNGQQ

Specific function: May regulate gene expression in response to changes in oxygen levels or to changes in the redox potential of the bacterial environment [H]

COG id: COG0664

COG function: function code T; cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH crp-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1787595, Length=224, Percent_Identity=36.1607142857143, Blast_Score=164, Evalue=5e-42,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018490
- InterPro:   IPR000595
- InterPro:   IPR001808
- InterPro:   IPR012318
- InterPro:   IPR014710
- InterPro:   IPR018335
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00027 cNMP_binding; PF00325 Crp [H]

EC number: NA

Molecular weight: Translated: 32635; Mature: 32635

Theoretical pI: Translated: 9.16; Mature: 9.16

Prosite motif: PS00042 HTH_CRP_1 ; PS51063 HTH_CRP_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.6 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
2.6 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLLTTRPPSPDSIPCCAGCSMARVCLAGNCDSDGEGPADGLAQRVIRLRKGEPLYLLGDP
CCCCCCCCCCCCCCCCCCCHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHCCCCEEEECCH
LAALFAVRVGTVKTHVATEDGRTQVVGFHFPGEVVGLDSIGRRQYASYATALEDTKVCMI
HHHHHHHHHHHHEEEEECCCCCEEEEEEECCCCEECCCHHHHHHHHHHHHHHCCCCEEEE
PMDVLRPLAACTPALASRVFRALDGYAQRTRALQTLLALMTAEERLVTFLLWISEGLAAR
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHC
GFSSSEFILRMSREEIGSYIGLTLETVSRQFSRLAECGLIRVKHRSVALVDKAGLRAIAD
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCEEEEHHHHHHHHHH
RSAISPIPPGTNRRRGGEQRVPAQALRTSAPAWATRTQPATAAMQADNPKINPFAWEAGN
CCCCCCCCCCCCCCCCCCCCCCHHHHHCCCCCCCCCCCCCHHHEECCCCCCCCEEECCCC
GQQ
CCC
>Mature Secondary Structure
MLLTTRPPSPDSIPCCAGCSMARVCLAGNCDSDGEGPADGLAQRVIRLRKGEPLYLLGDP
CCCCCCCCCCCCCCCCCCCHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHCCCCEEEECCH
LAALFAVRVGTVKTHVATEDGRTQVVGFHFPGEVVGLDSIGRRQYASYATALEDTKVCMI
HHHHHHHHHHHHEEEEECCCCCEEEEEEECCCCEECCCHHHHHHHHHHHHHHCCCCEEEE
PMDVLRPLAACTPALASRVFRALDGYAQRTRALQTLLALMTAEERLVTFLLWISEGLAAR
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHC
GFSSSEFILRMSREEIGSYIGLTLETVSRQFSRLAECGLIRVKHRSVALVDKAGLRAIAD
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCEEEEHHHHHHHHHH
RSAISPIPPGTNRRRGGEQRVPAQALRTSAPAWATRTQPATAAMQADNPKINPFAWEAGN
CCCCCCCCCCCCCCCCCCCCCCHHHHHCCCCCCCCCCCCCHHHEECCCCCCCCEEECCCC
GQQ
CCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: Fe [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7693656; 12910271 [H]