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The map label for this gene is ywbI [H]

Identifier: 73537917

GI number: 73537917

Start: 725683

End: 726591

Strand: Direct

Name: ywbI [H]

Synonym: Reut_B4084

Alternate gene names: 73537917

Gene position: 725683-726591 (Clockwise)

Preceding gene: 73537905

Following gene: 73537924

Centisome position: 26.62

GC content: 66.12

Gene sequence:

>909_bases
ATGCCTATTGATATCCGCGCGCTACGCTACTTTGTCGAAACTGCGCGACTGAGGAGTTTTACGCAGGCGGCCACGTCGCT
ATTCGTCACGCAATCGACTATCAGCAAGATGGTTCGCCAGCTGGAGGACGAGGTCGGGCAGCCGCTGCTGATCCGCGAAG
GCAAGACGGTGCGACTGACCGACGTGGGCCGTGTGGTGTATGAGCGCGGCCAGGAAGCGCTCGGCGTTGTGCACCGGCTC
ACGCTGGAGGTGGCGGATCTGTCATCGCTGGGACGCGGACAGTTGACCGTCGGCATTCCGCCCATGGTCAACCTGTTCTT
TTCGCCCGCGGTCAGCGCATTCCGCAAACGCTATCCGAATCTCGAACTGCATCTGGCCGAGCATGGCGGCCATCTGGTCG
AACAGATGGTGGCCAGCGGCGAACTGGAGGTGGGTGCCACGGTGCTGCCGGTGGACGACGGCGTGGAACTGGCCACCCAG
CCGTTCGCCAACTATCCGATCTGGGCAGTGGGGCCGCGCAAGGCGGCCTGGGCGCGCGGCAAGACCGTCAGCCTGGCGGC
GCTGCGCGATGAACCGCTGGTGTTGCTGACTGACGCGTTCTCGCTCACGCACAAGCTGCGCCTGGCGTTCCTGGAGGCGC
GCATGGAGCCGCGCGTGGTCGCGCAAAGCGGCCACTGGGATTTCCTGGCGTCAATGGCGGCTGCCGGGCTCGGTACGACG
TTCCTGCCTCAGCCCTTCCTGGCACGGTTGCAGGACCGCGACAACCTTGCGGTGGCGCGGCTGACGGAGCCGGCGATGGA
CTGGGCACTGGCGCATACCTGGCTGCCGGGCCGCTATCTTTCGCACGCGGCGCGGGCATGGCTCGCGGTCTGCGACGAAG
TACTGGGCGGGAAGACGCTGTCGGCGTGA

Upstream 100 bases:

>100_bases
CGGAGCGTGGAAGCGAAGTGTAGTCAAATGGCGGCCATTCCAATCATGATTTAAAATTCCTGGAATCATTCAATATTTTC
ATGGAAGTGCAGACACCGTC

Downstream 100 bases:

>100_bases
ACCTGTCTTGTCCCGGTGGGCTTGGGGCAGGCCGAATTGCTGGCGAGCACAGCAATGGTGGGCGGTGATCGTCCTATCGG
ACTTCTGGTGAAGGATAGAG

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 302; Mature: 301

Protein sequence:

>302_residues
MPIDIRALRYFVETARLRSFTQAATSLFVTQSTISKMVRQLEDEVGQPLLIREGKTVRLTDVGRVVYERGQEALGVVHRL
TLEVADLSSLGRGQLTVGIPPMVNLFFSPAVSAFRKRYPNLELHLAEHGGHLVEQMVASGELEVGATVLPVDDGVELATQ
PFANYPIWAVGPRKAAWARGKTVSLAALRDEPLVLLTDAFSLTHKLRLAFLEARMEPRVVAQSGHWDFLASMAAAGLGTT
FLPQPFLARLQDRDNLAVARLTEPAMDWALAHTWLPGRYLSHAARAWLAVCDEVLGGKTLSA

Sequences:

>Translated_302_residues
MPIDIRALRYFVETARLRSFTQAATSLFVTQSTISKMVRQLEDEVGQPLLIREGKTVRLTDVGRVVYERGQEALGVVHRL
TLEVADLSSLGRGQLTVGIPPMVNLFFSPAVSAFRKRYPNLELHLAEHGGHLVEQMVASGELEVGATVLPVDDGVELATQ
PFANYPIWAVGPRKAAWARGKTVSLAALRDEPLVLLTDAFSLTHKLRLAFLEARMEPRVVAQSGHWDFLASMAAAGLGTT
FLPQPFLARLQDRDNLAVARLTEPAMDWALAHTWLPGRYLSHAARAWLAVCDEVLGGKTLSA
>Mature_301_residues
PIDIRALRYFVETARLRSFTQAATSLFVTQSTISKMVRQLEDEVGQPLLIREGKTVRLTDVGRVVYERGQEALGVVHRLT
LEVADLSSLGRGQLTVGIPPMVNLFFSPAVSAFRKRYPNLELHLAEHGGHLVEQMVASGELEVGATVLPVDDGVELATQP
FANYPIWAVGPRKAAWARGKTVSLAALRDEPLVLLTDAFSLTHKLRLAFLEARMEPRVVAQSGHWDFLASMAAAGLGTTF
LPQPFLARLQDRDNLAVARLTEPAMDWALAHTWLPGRYLSHAARAWLAVCDEVLGGKTLSA

Specific function: Positive Regulatory Protein For The Cyn Operon. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI157672245, Length=300, Percent_Identity=30.3333333333333, Blast_Score=117, Evalue=1e-27,
Organism=Escherichia coli, GI1790399, Length=294, Percent_Identity=27.5510204081633, Blast_Score=94, Evalue=1e-20,
Organism=Escherichia coli, GI1788297, Length=264, Percent_Identity=25.3787878787879, Blast_Score=90, Evalue=1e-19,
Organism=Escherichia coli, GI1788887, Length=244, Percent_Identity=28.2786885245902, Blast_Score=81, Evalue=9e-17,
Organism=Escherichia coli, GI1788748, Length=295, Percent_Identity=26.4406779661017, Blast_Score=79, Evalue=3e-16,
Organism=Escherichia coli, GI1787879, Length=289, Percent_Identity=26.9896193771626, Blast_Score=79, Evalue=3e-16,
Organism=Escherichia coli, GI1790208, Length=246, Percent_Identity=23.5772357723577, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI145693105, Length=184, Percent_Identity=23.3695652173913, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1787530, Length=239, Percent_Identity=25.1046025104602, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1788481, Length=310, Percent_Identity=26.1290322580645, Blast_Score=66, Evalue=3e-12,
Organism=Escherichia coli, GI2367136, Length=247, Percent_Identity=21.8623481781377, Blast_Score=65, Evalue=7e-12,
Organism=Escherichia coli, GI145693193, Length=126, Percent_Identity=31.7460317460317, Blast_Score=65, Evalue=7e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 33169; Mature: 33038

Theoretical pI: Translated: 7.84; Mature: 7.84

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPIDIRALRYFVETARLRSFTQAATSLFVTQSTISKMVRQLEDEVGQPLLIREGKTVRLT
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCEEEEH
DVGRVVYERGQEALGVVHRLTLEVADLSSLGRGQLTVGIPPMVNLFFSPAVSAFRKRYPN
HHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCEEEECCCHHHHHHHHHHHHHHHHHCCC
LELHLAEHGGHLVEQMVASGELEVGATVLPVDDGVELATQPFANYPIWAVGPRKAAWARG
CEEEEHHCCCHHHHHHHHCCCEECCEEEEECCCCCHHHCCCCCCCCEEEECCCHHHHCCC
KTVSLAALRDEPLVLLTDAFSLTHKLRLAFLEARMEPRVVAQSGHWDFLASMAAAGLGTT
CEEEEEEECCCCEEEEECHHHHHHHHHHHHHHHCCCCEEEECCCCHHHHHHHHHHCCCCC
FLPQPFLARLQDRDNLAVARLTEPAMDWALAHTWLPGRYLSHAARAWLAVCDEVLGGKTL
CCCCHHHHHHCCCCCEEEEEHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCC
SA
CC
>Mature Secondary Structure 
PIDIRALRYFVETARLRSFTQAATSLFVTQSTISKMVRQLEDEVGQPLLIREGKTVRLT
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCEEEEH
DVGRVVYERGQEALGVVHRLTLEVADLSSLGRGQLTVGIPPMVNLFFSPAVSAFRKRYPN
HHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCEEEECCCHHHHHHHHHHHHHHHHHCCC
LELHLAEHGGHLVEQMVASGELEVGATVLPVDDGVELATQPFANYPIWAVGPRKAAWARG
CEEEEHHCCCHHHHHHHHCCCEECCEEEEECCCCCHHHCCCCCCCCEEEECCCHHHHCCC
KTVSLAALRDEPLVLLTDAFSLTHKLRLAFLEARMEPRVVAQSGHWDFLASMAAAGLGTT
CEEEEEEECCCCEEEEECHHHHHHHHHHHHHHHCCCCEEEECCCCHHHHHHHHHHCCCCC
FLPQPFLARLQDRDNLAVARLTEPAMDWALAHTWLPGRYLSHAARAWLAVCDEVLGGKTL
CCCCHHHHHHCCCCCEEEEEHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCC
SA
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7934828; 9384377 [H]