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The map label for this gene is aaeB [H]

Identifier: 73537916

GI number: 73537916

Start: 723490

End: 725538

Strand: Reverse

Name: aaeB [H]

Synonym: Reut_B4083

Alternate gene names: 73537916

Gene position: 725538-723490 (Counterclockwise)

Preceding gene: 73537918

Following gene: 73537915

Centisome position: 26.61

GC content: 68.52

Gene sequence:

>2049_bases
ATGCGCCCCCAAACCAGAACACTAAAACTCGATCTCATGGCCATGCGGCCGAATGCAAGACAGTGGCTGTTTTCGCTGAA
AGCATTCCTGGCCGCCATGCTCGCGCTCTATATCGCGCTTGCGCTCGGCCTGCCGCGGCCGTACTGGGCCATGGCGACGG
TGTACTTCGTCTCGCATCCGCTGACAGGCGCCACGCGTTCCAAGGCCGCGTATCGCGTCGCCGGCACCGTGCTGGGCGCC
GCCGCCGCCGTGGCGACCGTGCCGCTGCTGATCAACATGCCCATCGTGCTGATGGGCGCCATCTCGCTGTGGATCGTCGC
GCTTGTCTACCTGTCACTGCTGCAGCGCTCGCCGCGCGCGTATGTGTTTCTGCTGGCGGCGTACACGCTGCCGATCGTGG
CGCTGCCGGCGGTGGACCAGCCCGCGCAGATCTTCGACCTGGCCGTCGCGCGCATCGAAGAAATCGTCATCGGCATTGTC
TGCGCGGGCCTGGTCGGGTCGATCATCCTGCCGGCCAAGGTCGCTCCGGCCCTGCGCGCACGCGCCGCGAGCTGGCTGGC
GGATGCCGCGGCATGGGCTGACGACATCCTCTGCGCGAATCCTCGGGCCGACGCAGGGCGCCATCGCCTCGCCGCCGACA
TCCTCGCGTTGGATCAATTGATCGCCCAGCTTTCGTACGACACCGAAAGCGCCGGTTCCTTGCGCCATGCGCGCGCCTTG
CGGGCACGCATGACTACGCTGATGCCGTTGCTGTCCGCGCTGTCTGCGGTGCTGCAGGCGCTACGCATGCATCCGGCCGG
CGTGCCGGCACCGCTCGCGCAGGCGTTGTCGGCGCTCTCGCAATGGCTGCGCGGTGGCCTGGCTGGCTCGCCGCCGCATG
CGGATCGCCATGCGCTCGCCAGCGCCGCCGCAGACAGCTGGCACGCGCAGTTGCTCACGGCGGCAAGCAGCCAGCTCACG
CAACTGGCCGCGTTGTGCAGCGACAGCGCAGCGCTCCAGCATGGCATCGGCGACCGGCCCGACCAGCCGCTTCCGAAACT
GAGCGATTCCCCCGCTGCCGCAACCATGCCGGCAAGGGGTGCCCTGCATCACGACCACGGCATGCTGCTGTTCGGTGCCG
CGTCCACCGGGCTGGCGGTGTTCTGCGCCGGACTGCTGTGGATCTTCTCGGGCTGGACAGACGGCGCCGGGCCGGTGGCA
GTGTCCTCCATCGCATGCTGCTTCTTCGCGACCATCGACGAGCCGCGGCCGGTCGCGCGATCTTTCCTGCGCTGGAGCGC
GGTCTGCTTCGTCGTGGCCTCGTTCTACCTGTTCCTGGTGGTACCGCATGCGCAGAACTTCGAGGCGCTCGCTGGCATGC
TGGCCGTGCCCTACCTTGGCATCGGCATGCTGATCACACGGCCCGGCTTCAACCTGATTGCCATGCTGCTGTCGGTGAAC
ACGGCATCGTTCGCCAATATCCAGAGCGTCTACGACGCCAATTTCCTTGGCACGTTCAACGGCAGCCTTGCCAATGCCGC
GGCCATGCTGTTCGCACCGTTGTGGGCGCTGGCCACGCGTCCGTTCGGCGCAAGCGTGGCCGCGCGCCGGCTGATCCGCG
CTAGCTGGCAGGACCTGGCCGGCGCCGCCGCATGGCCGGGTGCGGACCATGACGCGAAGCTTGGCGCGCGCATGCTGGAT
CGCCTCGGCCAGTTGGTGCCACGGCTTGGCGCCGTGCGCGCCGGCCCGGATGGCTTCAGCGAACTGCATGTTGGATTCTG
CGCACTGGCGCTGCGGCGCGCGCTGCCGTCGTTACCCACCGTCGCACGGCGGCCCGTCCGGCGTGTGCTGGCACTGGTGG
CGCGCCACTACCGTGCACGCCTGCGCAGCGGCCATGCCGCAGCGCCGTCCCCCGAATTGCCCGCTTGCATCGACTTGGCT
ATCGCCCAGATCGCCGCGCTGCCGGGGCATCGGGACGAGGCGATTGCCGCGCTCGTCGTACTGCGTGTCACGCTGCACGA
GCCACACGTCCCCGGCGTACCGGATACAGGAGCCGGCGTTGAACACTGA

Upstream 100 bases:

>100_bases
TTTTAAATCATGATTGGAATGGCCGCCATTTGACTACACTTCGCTTCCACGCTCCGCTTGCGCCTGCGTCCGGCAACAGG
GCCGTACCAGGCGGCGCACG

Downstream 100 bases:

>100_bases
AATCGACCTTTACGGCGTGTTCGTGCCTGCTCTGCTGGTGCTGATGCTTGCAGCGTTCGCGGCCACCACATGCGTGCGCG
TGCTGCTCGCGCGGCTCGGG

Product: fusaric acid resistance protein

Products: NA

Alternate protein names: pHBA efflux pump protein B [H]

Number of amino acids: Translated: 682; Mature: 682

Protein sequence:

>682_residues
MRPQTRTLKLDLMAMRPNARQWLFSLKAFLAAMLALYIALALGLPRPYWAMATVYFVSHPLTGATRSKAAYRVAGTVLGA
AAAVATVPLLINMPIVLMGAISLWIVALVYLSLLQRSPRAYVFLLAAYTLPIVALPAVDQPAQIFDLAVARIEEIVIGIV
CAGLVGSIILPAKVAPALRARAASWLADAAAWADDILCANPRADAGRHRLAADILALDQLIAQLSYDTESAGSLRHARAL
RARMTTLMPLLSALSAVLQALRMHPAGVPAPLAQALSALSQWLRGGLAGSPPHADRHALASAAADSWHAQLLTAASSQLT
QLAALCSDSAALQHGIGDRPDQPLPKLSDSPAAATMPARGALHHDHGMLLFGAASTGLAVFCAGLLWIFSGWTDGAGPVA
VSSIACCFFATIDEPRPVARSFLRWSAVCFVVASFYLFLVVPHAQNFEALAGMLAVPYLGIGMLITRPGFNLIAMLLSVN
TASFANIQSVYDANFLGTFNGSLANAAAMLFAPLWALATRPFGASVAARRLIRASWQDLAGAAAWPGADHDAKLGARMLD
RLGQLVPRLGAVRAGPDGFSELHVGFCALALRRALPSLPTVARRPVRRVLALVARHYRARLRSGHAAAPSPELPACIDLA
IAQIAALPGHRDEAIAALVVLRVTLHEPHVPGVPDTGAGVEH

Sequences:

>Translated_682_residues
MRPQTRTLKLDLMAMRPNARQWLFSLKAFLAAMLALYIALALGLPRPYWAMATVYFVSHPLTGATRSKAAYRVAGTVLGA
AAAVATVPLLINMPIVLMGAISLWIVALVYLSLLQRSPRAYVFLLAAYTLPIVALPAVDQPAQIFDLAVARIEEIVIGIV
CAGLVGSIILPAKVAPALRARAASWLADAAAWADDILCANPRADAGRHRLAADILALDQLIAQLSYDTESAGSLRHARAL
RARMTTLMPLLSALSAVLQALRMHPAGVPAPLAQALSALSQWLRGGLAGSPPHADRHALASAAADSWHAQLLTAASSQLT
QLAALCSDSAALQHGIGDRPDQPLPKLSDSPAAATMPARGALHHDHGMLLFGAASTGLAVFCAGLLWIFSGWTDGAGPVA
VSSIACCFFATIDEPRPVARSFLRWSAVCFVVASFYLFLVVPHAQNFEALAGMLAVPYLGIGMLITRPGFNLIAMLLSVN
TASFANIQSVYDANFLGTFNGSLANAAAMLFAPLWALATRPFGASVAARRLIRASWQDLAGAAAWPGADHDAKLGARMLD
RLGQLVPRLGAVRAGPDGFSELHVGFCALALRRALPSLPTVARRPVRRVLALVARHYRARLRSGHAAAPSPELPACIDLA
IAQIAALPGHRDEAIAALVVLRVTLHEPHVPGVPDTGAGVEH
>Mature_682_residues
MRPQTRTLKLDLMAMRPNARQWLFSLKAFLAAMLALYIALALGLPRPYWAMATVYFVSHPLTGATRSKAAYRVAGTVLGA
AAAVATVPLLINMPIVLMGAISLWIVALVYLSLLQRSPRAYVFLLAAYTLPIVALPAVDQPAQIFDLAVARIEEIVIGIV
CAGLVGSIILPAKVAPALRARAASWLADAAAWADDILCANPRADAGRHRLAADILALDQLIAQLSYDTESAGSLRHARAL
RARMTTLMPLLSALSAVLQALRMHPAGVPAPLAQALSALSQWLRGGLAGSPPHADRHALASAAADSWHAQLLTAASSQLT
QLAALCSDSAALQHGIGDRPDQPLPKLSDSPAAATMPARGALHHDHGMLLFGAASTGLAVFCAGLLWIFSGWTDGAGPVA
VSSIACCFFATIDEPRPVARSFLRWSAVCFVVASFYLFLVVPHAQNFEALAGMLAVPYLGIGMLITRPGFNLIAMLLSVN
TASFANIQSVYDANFLGTFNGSLANAAAMLFAPLWALATRPFGASVAARRLIRASWQDLAGAAAWPGADHDAKLGARMLD
RLGQLVPRLGAVRAGPDGFSELHVGFCALALRRALPSLPTVARRPVRRVLALVARHYRARLRSGHAAAPSPELPACIDLA
IAQIAALPGHRDEAIAALVVLRVTLHEPHVPGVPDTGAGVEH

Specific function: Efflux pump whose substrates are p-hydroxybenzoic acid (pHBA), 6-hydroxy-2-naphthoic and 2-hydroxycinnamate. Could function as a metabolic relief valve, allowing to eliminate certain compounds when they accumulate to high levels in the cell [H]

COG id: COG1289

COG function: function code S; Predicted membrane protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aromatic acid exporter ArAE (TC 2.A.85) family [H]

Homologues:

Organism=Escherichia coli, GI1787933, Length=555, Percent_Identity=27.5675675675676, Blast_Score=102, Evalue=9e-23,
Organism=Escherichia coli, GI1789636, Length=507, Percent_Identity=23.6686390532544, Blast_Score=93, Evalue=6e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006726 [H]

Pfam domain/function: PF04632 FUSC [H]

EC number: NA

Molecular weight: Translated: 71938; Mature: 71938

Theoretical pI: Translated: 10.00; Mature: 10.00

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRPQTRTLKLDLMAMRPNARQWLFSLKAFLAAMLALYIALALGLPRPYWAMATVYFVSHP
CCCCCCEEEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCC
LTGATRSKAAYRVAGTVLGAAAAVATVPLLINMPIVLMGAISLWIVALVYLSLLQRSPRA
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCH
YVFLLAAYTLPIVALPAVDQPAQIFDLAVARIEEIVIGIVCAGLVGSIILPAKVAPALRA
HHHHHHHHHHHHHEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RAASWLADAAAWADDILCANPRADAGRHRLAADILALDQLIAQLSYDTESAGSLRHARAL
HHHHHHHHHHHHHHHHEECCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHH
RARMTTLMPLLSALSAVLQALRMHPAGVPAPLAQALSALSQWLRGGLAGSPPHADRHALA
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHH
SAAADSWHAQLLTAASSQLTQLAALCSDSAALQHGIGDRPDQPLPKLSDSPAAATMPARG
HHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCC
ALHHDHGMLLFGAASTGLAVFCAGLLWIFSGWTDGAGPVAVSSIACCFFATIDEPRPVAR
CCCCCCCEEEEECCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCCCCHHHH
SFLRWSAVCFVVASFYLFLVVPHAQNFEALAGMLAVPYLGIGMLITRPGFNLIAMLLSVN
HHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHC
TASFANIQSVYDANFLGTFNGSLANAAAMLFAPLWALATRPFGASVAARRLIRASWQDLA
CHHHHHHHHHHCCCCEECCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHC
GAAAWPGADHDAKLGARMLDRLGQLVPRLGAVRAGPDGFSELHVGFCALALRRALPSLPT
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCH
VARRPVRRVLALVARHYRARLRSGHAAAPSPELPACIDLAIAQIAALPGHRDEAIAALVV
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHH
LRVTLHEPHVPGVPDTGAGVEH
HHHHHCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MRPQTRTLKLDLMAMRPNARQWLFSLKAFLAAMLALYIALALGLPRPYWAMATVYFVSHP
CCCCCCEEEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCC
LTGATRSKAAYRVAGTVLGAAAAVATVPLLINMPIVLMGAISLWIVALVYLSLLQRSPRA
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCH
YVFLLAAYTLPIVALPAVDQPAQIFDLAVARIEEIVIGIVCAGLVGSIILPAKVAPALRA
HHHHHHHHHHHHHEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RAASWLADAAAWADDILCANPRADAGRHRLAADILALDQLIAQLSYDTESAGSLRHARAL
HHHHHHHHHHHHHHHHEECCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHH
RARMTTLMPLLSALSAVLQALRMHPAGVPAPLAQALSALSQWLRGGLAGSPPHADRHALA
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHH
SAAADSWHAQLLTAASSQLTQLAALCSDSAALQHGIGDRPDQPLPKLSDSPAAATMPARG
HHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCC
ALHHDHGMLLFGAASTGLAVFCAGLLWIFSGWTDGAGPVAVSSIACCFFATIDEPRPVAR
CCCCCCCEEEEECCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCCCCHHHH
SFLRWSAVCFVVASFYLFLVVPHAQNFEALAGMLAVPYLGIGMLITRPGFNLIAMLLSVN
HHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHC
TASFANIQSVYDANFLGTFNGSLANAAAMLFAPLWALATRPFGASVAARRLIRASWQDLA
CHHHHHHHHHHCCCCEECCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHC
GAAAWPGADHDAKLGARMLDRLGQLVPRLGAVRAGPDGFSELHVGFCALALRRALPSLPT
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCH
VARRPVRRVLALVARHYRARLRSGHAAAPSPELPACIDLAIAQIAALPGHRDEAIAALVV
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHH
LRVTLHEPHVPGVPDTGAGVEH
HHHHHCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA