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The map label for this gene is nodT [H]

Identifier: 73537914

GI number: 73537914

Start: 720860

End: 722413

Strand: Reverse

Name: nodT [H]

Synonym: Reut_B4081

Alternate gene names: 73537914

Gene position: 722413-720860 (Counterclockwise)

Preceding gene: 73537915

Following gene: 73537913

Centisome position: 26.5

GC content: 68.98

Gene sequence:

>1554_bases
GTGAGGATATGGCTATGGATATGGCTAATGCCACTGGTGCCGGCCTTGTTCGCGTGCACCACAGTCGGACCGGATTACCA
CTTACCGGACACCGCCGCCGTACGCGCCCCGGAAGCCAACGGGAAGCTGCTGGGCAGTGCGAATCCCGCTGTATCGATCG
GCCCGGTCCCCGATGCGTGGTGGCAACTCTACAACGATCCCCGGCTCGACCGCCTGGTCCGCGAGGCGCTCGCGGCCAAC
ACGGATATCCGCGTGGCATCGGCCAACCTGCGCCGGGCCACGGCTGCGTTGCACGAGGTAGAGGCGGAGAACCTGCCGCA
AGGCGGCATCAGCGCGAGCGTCTCCCGCGCCCAGTTGTCGGGCCAGAGCTACCTGCAGACGACCAAGCCGCCGGTGTTCA
ACCTCGGGGACTTCGGGCCCGGCGTGTCCTACCTGATCGACTTCTTCGGCAAGCTTGCGCGGGCCGATGAAGCGGCGCTG
GCGAACATGCAGGCCAGCGAAGCAGCCCTCGACGCCGCCCGCGTTGGCGTGGCGGCCCAGACGGTGCGCGCCTACGTGCA
AGGCTGCGCGGCCAGCCATGAACTGGAAGTGGCCCGGCACCAGATTGCGCTGCAGGAACGTGCGGTCGATGCCACGCGCA
GACTCGCATCTGCCGGCCGGGCCGAACCCACGGACACCGTGCGCGCCCAGGCGCGTGTGGAGGCCTTGCGCGCCGCGCTG
CCCCCGCTGGCAGCCGCGCGCGAAGCCGCCGGGTTCCGACTGGCGCTGGTGCTCGGCAAGCCGCCGGCAGCCCTGCCAGC
AGAGGACATCGAATGCCACGAGGAACCGCCGCTGACACAACCGCTGCCGGTTGGCGACGGCGCCGCGCTACTCAAGCGCC
GGCCCGACATCCGGCAAGCCGAACGCGAACTGGCCGCTGCCACCGCGAAGATCGGGGTGGCCACGGCCGACCTGTATCCA
AGCATCCGGATCGGCGCGTCGGCCGGGCTAACCGGCTTGCTGAGCGACCTGGGCAGTGGGCCTACGGTCCGCTGGAGCAT
TGGCCCGATGCTGAGCTGGAATTTCCCCACCAATGGCGTGCGCCCGCGCATTGCACGCATGGAAGCCGGTGCAGATGCCG
CGCTCGCGCATTTTGATGGTGTGGTATTGCGAGCATTGCAGGAGACCGAAACCGCACTCAGCGCCTACGCGCGCGAGCTG
GAGCGACAGCACGCGCTGCAGCTCGCGCGCGACCAGGCAGTCGAAGCCGCCCGGCAGGAACGGCGGCGTTACGAGGCTGG
ACGTACGCCATACCTGGCGCGGCTGGATGCAGAGCGAACGCTGGCCGATGCGGAAGCTGCGCTCGCGGAGTCGGACAGCC
TTGTTGCCATGCGTCAGATCGACCTGTTTCTGGCGCTTGGCGGAGGGTGGCAGCAGCCTGAGGGGGCTCCGCGAGCGGAG
GAACGCGGCCACGACGCCTCTCTTCCATTGCCAAAATCGGATACTCGCCCGGACGCCGTCGTGCTCCTGCACGGTGCAGC
GCCACCCGCAAGGCCCTCTTCGCCCCCCGCCTGA

Upstream 100 bases:

>100_bases
CCGTGCGCATCACGTTTGATGCGGTCCCGCCGGAGGTGCGACTGATTTCGGGACGCACGGCCACAGTGTCCGTGCAGCAG
CCAGTCGCGGAGCGCAAGCC

Downstream 100 bases:

>100_bases
GGCCAAATCTCGCGCCAATTCAGCGCTTTGGCACGGCTTATCCGCGTCCGCAACCTTGGTTCACCCTAGTAATTCCCCCG
GTATGACCGTTGCCGATCCT

Product: RND efflux system outer membrane lipoprotein NodT

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 517; Mature: 517

Protein sequence:

>517_residues
MRIWLWIWLMPLVPALFACTTVGPDYHLPDTAAVRAPEANGKLLGSANPAVSIGPVPDAWWQLYNDPRLDRLVREALAAN
TDIRVASANLRRATAALHEVEAENLPQGGISASVSRAQLSGQSYLQTTKPPVFNLGDFGPGVSYLIDFFGKLARADEAAL
ANMQASEAALDAARVGVAAQTVRAYVQGCAASHELEVARHQIALQERAVDATRRLASAGRAEPTDTVRAQARVEALRAAL
PPLAAAREAAGFRLALVLGKPPAALPAEDIECHEEPPLTQPLPVGDGAALLKRRPDIRQAERELAAATAKIGVATADLYP
SIRIGASAGLTGLLSDLGSGPTVRWSIGPMLSWNFPTNGVRPRIARMEAGADAALAHFDGVVLRALQETETALSAYAREL
ERQHALQLARDQAVEAARQERRRYEAGRTPYLARLDAERTLADAEAALAESDSLVAMRQIDLFLALGGGWQQPEGAPRAE
ERGHDASLPLPKSDTRPDAVVLLHGAAPPARPSSPPA

Sequences:

>Translated_517_residues
MRIWLWIWLMPLVPALFACTTVGPDYHLPDTAAVRAPEANGKLLGSANPAVSIGPVPDAWWQLYNDPRLDRLVREALAAN
TDIRVASANLRRATAALHEVEAENLPQGGISASVSRAQLSGQSYLQTTKPPVFNLGDFGPGVSYLIDFFGKLARADEAAL
ANMQASEAALDAARVGVAAQTVRAYVQGCAASHELEVARHQIALQERAVDATRRLASAGRAEPTDTVRAQARVEALRAAL
PPLAAAREAAGFRLALVLGKPPAALPAEDIECHEEPPLTQPLPVGDGAALLKRRPDIRQAERELAAATAKIGVATADLYP
SIRIGASAGLTGLLSDLGSGPTVRWSIGPMLSWNFPTNGVRPRIARMEAGADAALAHFDGVVLRALQETETALSAYAREL
ERQHALQLARDQAVEAARQERRRYEAGRTPYLARLDAERTLADAEAALAESDSLVAMRQIDLFLALGGGWQQPEGAPRAE
ERGHDASLPLPKSDTRPDAVVLLHGAAPPARPSSPPA
>Mature_517_residues
MRIWLWIWLMPLVPALFACTTVGPDYHLPDTAAVRAPEANGKLLGSANPAVSIGPVPDAWWQLYNDPRLDRLVREALAAN
TDIRVASANLRRATAALHEVEAENLPQGGISASVSRAQLSGQSYLQTTKPPVFNLGDFGPGVSYLIDFFGKLARADEAAL
ANMQASEAALDAARVGVAAQTVRAYVQGCAASHELEVARHQIALQERAVDATRRLASAGRAEPTDTVRAQARVEALRAAL
PPLAAAREAAGFRLALVLGKPPAALPAEDIECHEEPPLTQPLPVGDGAALLKRRPDIRQAERELAAATAKIGVATADLYP
SIRIGASAGLTGLLSDLGSGPTVRWSIGPMLSWNFPTNGVRPRIARMEAGADAALAHFDGVVLRALQETETALSAYAREL
ERQHALQLARDQAVEAARQERRRYEAGRTPYLARLDAERTLADAEAALAESDSLVAMRQIDLFLALGGGWQQPEGAPRAE
ERGHDASLPLPKSDTRPDAVVLLHGAAPPARPSSPPA

Specific function: In Pathogenic Strains It Allows The Bacteria To Invade Brain Microvascular Endothelial Cells (Bmec) Thus Allowing It To Cross The Blood-Brain Barrier And Cause Neonatal Meningitis. [C]

COG id: COG1538

COG function: function code MU; Outer membrane protein

Gene ontology:

Cell location: Cell membrane; Lipid-anchor (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family [H]

Homologues:

Organism=Escherichia coli, GI1786785, Length=483, Percent_Identity=26.7080745341615, Blast_Score=112, Evalue=6e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003423
- InterPro:   IPR010131 [H]

Pfam domain/function: PF02321 OEP [H]

EC number: NA

Molecular weight: Translated: 55035; Mature: 55035

Theoretical pI: Translated: 6.27; Mature: 6.27

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRIWLWIWLMPLVPALFACTTVGPDYHLPDTAAVRAPEANGKLLGSANPAVSIGPVPDAW
CEEEHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEECCCCCCCEEECCCCCEEECCCCHHH
WQLYNDPRLDRLVREALAANTDIRVASANLRRATAALHEVEAENLPQGGISASVSRAQLS
HHHCCCCHHHHHHHHHHHCCCCEEEECCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHC
GQSYLQTTKPPVFNLGDFGPGVSYLIDFFGKLARADEAALANMQASEAALDAARVGVAAQ
CHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHH
TVRAYVQGCAASHELEVARHQIALQERAVDATRRLASAGRAEPTDTVRAQARVEALRAAL
HHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHC
PPLAAAREAAGFRLALVLGKPPAALPAEDIECHEEPPLTQPLPVGDGAALLKRRPDIRQA
CCHHHHHHCCCEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHCCCCHHHH
ERELAAATAKIGVATADLYPSIRIGASAGLTGLLSDLGSGPTVRWSIGPMLSWNFPTNGV
HHHHHHHHHHHCEEECCCCCCEEECCCCCHHHHHHHHCCCCEEEEECCCEEECCCCCCCC
RPRIARMEAGADAALAHFDGVVLRALQETETALSAYARELERQHALQLARDQAVEAARQE
CCHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RRRYEAGRTPYLARLDAERTLADAEAALAESDSLVAMRQIDLFLALGGGWQQPEGAPRAE
HHHHHCCCCCEEEECCHHHHHHHHHHHHHCCCCCHHHHHHEEEEEECCCCCCCCCCCCHH
ERGHDASLPLPKSDTRPDAVVLLHGAAPPARPSSPPA
HCCCCCCCCCCCCCCCCCEEEEEECCCCCCCCCCCCC
>Mature Secondary Structure
MRIWLWIWLMPLVPALFACTTVGPDYHLPDTAAVRAPEANGKLLGSANPAVSIGPVPDAW
CEEEHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEECCCCCCCEEECCCCCEEECCCCHHH
WQLYNDPRLDRLVREALAANTDIRVASANLRRATAALHEVEAENLPQGGISASVSRAQLS
HHHCCCCHHHHHHHHHHHCCCCEEEECCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHC
GQSYLQTTKPPVFNLGDFGPGVSYLIDFFGKLARADEAALANMQASEAALDAARVGVAAQ
CHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHH
TVRAYVQGCAASHELEVARHQIALQERAVDATRRLASAGRAEPTDTVRAQARVEALRAAL
HHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHC
PPLAAAREAAGFRLALVLGKPPAALPAEDIECHEEPPLTQPLPVGDGAALLKRRPDIRQA
CCHHHHHHCCCEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHCCCCHHHH
ERELAAATAKIGVATADLYPSIRIGASAGLTGLLSDLGSGPTVRWSIGPMLSWNFPTNGV
HHHHHHHHHHHCEEECCCCCCEEECCCCCHHHHHHHHCCCCEEEEECCCEEECCCCCCCC
RPRIARMEAGADAALAHFDGVVLRALQETETALSAYARELERQHALQLARDQAVEAARQE
CCHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RRRYEAGRTPYLARLDAERTLADAEAALAESDSLVAMRQIDLFLALGGGWQQPEGAPRAE
HHHHHCCCCCEEEECCHHHHHHHHHHHHHCCCCCHHHHHHEEEEEECCCCCCCCCCCCHH
ERGHDASLPLPKSDTRPDAVVLLHGAAPPARPSSPPA
HCCCCCCCCCCCCCCCCCEEEEEECCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2338917; 2622339 [H]