Click here to switch to the map view.

The map label for this gene is 73537906

Identifier: 73537906

GI number: 73537906

Start: 713663

End: 715333

Strand: Reverse

Name: 73537906

Synonym: Reut_B4073

Alternate gene names: NA

Gene position: 715333-713663 (Counterclockwise)

Preceding gene: 73537907

Following gene: 73537904

Centisome position: 26.24

GC content: 67.92

Gene sequence:

>1671_bases
ATGACAAGACAGACCATGAACGATACTGCCCCCTCATCGTCCACTCCGCAGCCCACCCCGCAGCCCGGCCGGCGACAGTG
GCTGAGCCACCTGGCCGGCGCCGCCGTGACCACGGTTGCCGCCGCGGCCATGACCAGCCGGACCGCCAGCGCCGCCCCTG
CGGGCACGGCACCTGCCGCGTCCGGCCCCGGCACCGCCGGCGGTGGGACGCCAGACCCGATCGTGCTGATGCCGGCGTGG
CAGCTTTCACGCGAGATCCGCGGCGGCCGCCTGTCCTGCCGCCAGGTCATGAATGCCTACCTGGCGCATATCGACCGCGT
CAATCCGGTGACCAACGCCATCGTCGCGCTGCGGGATCGCGATGCCCTGATGCAGGAAGCCGCCGCTGCCGACGAGGCGT
TCGCCGCGCGCAAAGTGGCGGGATGGATGCACGGCGTGCCGCAGGCGCCGAAGGATCTGGCCCTCACGCGCGGCATTCGT
ACCACGTTCGGCTCGCCGATCTTCAAGGACAACGTGCCGACGTCCGACGCAATCATCGTAGAACGCGTGCGCAAATCCGG
CGCGATCCTGCTCGGCAAGACCAATACGCCCGAGTTCGGCCTGGGCTCGCAGACCTTCAACCCGGTGTATGGCCCCACGC
GCAATCCGTACGACAGCACGCGCACCGCGGGCGGCAGCAGCGGCGGCGCCGCGGCGGCACTGGCCATGCGTCTGCTGCCT
GTGGCGGACGGCAGCGATTTCGGCGGTTCGCTGCGCAACCCGGCCGGGTTCTGCAATGTTTATGGCTTCCGTCCTTCGGC
GGGACGCGTGCCCTATGGGCCCACGCCGGAAGTCTTTATCCAGCAGCTCGGCTATGAGGGCCCGATGGGCCGCACGGTCG
CTGACGTGGCCTTGCTACTCGCCACCCAGGCCGGCCCCGACCCGCGCACGCCGCAGGCGCTCGCGCCAGACCCAGTGCTC
GCCACGCTGACGCCGGACAACGTCATGGCCGCGCTGTCGACGAACCTGAAGGGCAAGCGCGTGGCATGGCTCGGCGACTG
GGACGGCTATCTGCCGATGGAAGACGGCATCCTTCAGCTGTGCGAGCAAGCCCTGCAGGCCTTCCCGGCCTTTGGCGTCG
GTGTCGACAAGATCAAGCCGCCTTTCTCACCCGAGCGCCTGTGGAAGACCTGGCTCGTGCACCGGCACTTCCTGGTCGGC
AACGGCATGCTGCCGTTCTACCGCGACGAAGCCAAGCGCGCGCTGCTCAAGCCCGAAGCGATCTGGGAAATCGAAGGTGC
GCTCAAGCTTAGCGGCGCGGACATCTATGCGGCCAGCGCCGACCGCAGCGCGTGGTATCAGGCTGTGGAAGGCGTCTTTG
CCAAATTCGACTACATCGCCGTGCCGACCGCACAGGTCTTTCCGTTCGATGTGCGTCAACCGTGGCCCAAGGAAATCGCT
GGCCGGCAAATGGATACCTACCACCGCTGGATGGAAGTCGTATTCCCGTGGACGTTGTCGGGCTGCCCGGCAATCAGCGT
GCCGGTCGGCTTCGGCAAGAACGGGCTGCCGATGGGCATGCAACTCATTGGCCGTCCGCGCGATGACCTGAGCGTCTTGC
GCCTGGCTCGGGCATACGAGCAGGAACGCGACTGGGTGGGCCGCCACCTGCCGCGCGCGGTGATGGCCTGA

Upstream 100 bases:

>100_bases
CGGCCGCGAAATGGGCCGCGCCGTGTTCGACCACTATACCGAGACCAAATCGGTCATGATCGCCGTGTAATTGCCGCCGG
CTGCCGACGGGTTTCCCACC

Downstream 100 bases:

>100_bases
CGACGGAAAGACCGGTCAGCGGCGCGCGAGCGTCGCTGACGGCAGTTCGCCGAAGAACGCGCGGTACTGCGCTGCAAATC
GCGGCAGATGCTGGAAGCCG

Product: amidase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 556; Mature: 555

Protein sequence:

>556_residues
MTRQTMNDTAPSSSTPQPTPQPGRRQWLSHLAGAAVTTVAAAAMTSRTASAAPAGTAPAASGPGTAGGGTPDPIVLMPAW
QLSREIRGGRLSCRQVMNAYLAHIDRVNPVTNAIVALRDRDALMQEAAAADEAFAARKVAGWMHGVPQAPKDLALTRGIR
TTFGSPIFKDNVPTSDAIIVERVRKSGAILLGKTNTPEFGLGSQTFNPVYGPTRNPYDSTRTAGGSSGGAAAALAMRLLP
VADGSDFGGSLRNPAGFCNVYGFRPSAGRVPYGPTPEVFIQQLGYEGPMGRTVADVALLLATQAGPDPRTPQALAPDPVL
ATLTPDNVMAALSTNLKGKRVAWLGDWDGYLPMEDGILQLCEQALQAFPAFGVGVDKIKPPFSPERLWKTWLVHRHFLVG
NGMLPFYRDEAKRALLKPEAIWEIEGALKLSGADIYAASADRSAWYQAVEGVFAKFDYIAVPTAQVFPFDVRQPWPKEIA
GRQMDTYHRWMEVVFPWTLSGCPAISVPVGFGKNGLPMGMQLIGRPRDDLSVLRLARAYEQERDWVGRHLPRAVMA

Sequences:

>Translated_556_residues
MTRQTMNDTAPSSSTPQPTPQPGRRQWLSHLAGAAVTTVAAAAMTSRTASAAPAGTAPAASGPGTAGGGTPDPIVLMPAW
QLSREIRGGRLSCRQVMNAYLAHIDRVNPVTNAIVALRDRDALMQEAAAADEAFAARKVAGWMHGVPQAPKDLALTRGIR
TTFGSPIFKDNVPTSDAIIVERVRKSGAILLGKTNTPEFGLGSQTFNPVYGPTRNPYDSTRTAGGSSGGAAAALAMRLLP
VADGSDFGGSLRNPAGFCNVYGFRPSAGRVPYGPTPEVFIQQLGYEGPMGRTVADVALLLATQAGPDPRTPQALAPDPVL
ATLTPDNVMAALSTNLKGKRVAWLGDWDGYLPMEDGILQLCEQALQAFPAFGVGVDKIKPPFSPERLWKTWLVHRHFLVG
NGMLPFYRDEAKRALLKPEAIWEIEGALKLSGADIYAASADRSAWYQAVEGVFAKFDYIAVPTAQVFPFDVRQPWPKEIA
GRQMDTYHRWMEVVFPWTLSGCPAISVPVGFGKNGLPMGMQLIGRPRDDLSVLRLARAYEQERDWVGRHLPRAVMA
>Mature_555_residues
TRQTMNDTAPSSSTPQPTPQPGRRQWLSHLAGAAVTTVAAAAMTSRTASAAPAGTAPAASGPGTAGGGTPDPIVLMPAWQ
LSREIRGGRLSCRQVMNAYLAHIDRVNPVTNAIVALRDRDALMQEAAAADEAFAARKVAGWMHGVPQAPKDLALTRGIRT
TFGSPIFKDNVPTSDAIIVERVRKSGAILLGKTNTPEFGLGSQTFNPVYGPTRNPYDSTRTAGGSSGGAAAALAMRLLPV
ADGSDFGGSLRNPAGFCNVYGFRPSAGRVPYGPTPEVFIQQLGYEGPMGRTVADVALLLATQAGPDPRTPQALAPDPVLA
TLTPDNVMAALSTNLKGKRVAWLGDWDGYLPMEDGILQLCEQALQAFPAFGVGVDKIKPPFSPERLWKTWLVHRHFLVGN
GMLPFYRDEAKRALLKPEAIWEIEGALKLSGADIYAASADRSAWYQAVEGVFAKFDYIAVPTAQVFPFDVRQPWPKEIAG
RQMDTYHRWMEVVFPWTLSGCPAISVPVGFGKNGLPMGMQLIGRPRDDLSVLRLARAYEQERDWVGRHLPRAVMA

Specific function: Unknown

COG id: COG0154

COG function: function code J; Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the amidase family [H]

Homologues:

Organism=Homo sapiens, GI195972892, Length=249, Percent_Identity=35.7429718875502, Blast_Score=138, Evalue=1e-32,
Organism=Homo sapiens, GI222831590, Length=250, Percent_Identity=31.2, Blast_Score=110, Evalue=5e-24,
Organism=Homo sapiens, GI166795287, Length=188, Percent_Identity=27.6595744680851, Blast_Score=68, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17537465, Length=255, Percent_Identity=31.7647058823529, Blast_Score=114, Evalue=2e-25,
Organism=Caenorhabditis elegans, GI17538252, Length=197, Percent_Identity=35.5329949238579, Blast_Score=102, Evalue=6e-22,
Organism=Caenorhabditis elegans, GI17556264, Length=304, Percent_Identity=28.6184210526316, Blast_Score=92, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI17543272, Length=171, Percent_Identity=32.1637426900585, Blast_Score=88, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI71990152, Length=159, Percent_Identity=34.5911949685535, Blast_Score=85, Evalue=9e-17,
Organism=Caenorhabditis elegans, GI17556276, Length=354, Percent_Identity=26.271186440678, Blast_Score=81, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17556278, Length=354, Percent_Identity=26.271186440678, Blast_Score=80, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI17538254, Length=204, Percent_Identity=30.8823529411765, Blast_Score=74, Evalue=3e-13,
Organism=Saccharomyces cerevisiae, GI6319685, Length=448, Percent_Identity=27.0089285714286, Blast_Score=113, Evalue=8e-26,
Organism=Saccharomyces cerevisiae, GI6323950, Length=177, Percent_Identity=33.8983050847458, Blast_Score=75, Evalue=2e-14,
Organism=Saccharomyces cerevisiae, GI6320448, Length=231, Percent_Identity=25.5411255411255, Blast_Score=72, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24644968, Length=518, Percent_Identity=26.0617760617761, Blast_Score=123, Evalue=4e-28,
Organism=Drosophila melanogaster, GI45550774, Length=254, Percent_Identity=34.6456692913386, Blast_Score=122, Evalue=5e-28,
Organism=Drosophila melanogaster, GI24648435, Length=257, Percent_Identity=34.2412451361868, Blast_Score=122, Evalue=6e-28,
Organism=Drosophila melanogaster, GI24648437, Length=257, Percent_Identity=34.2412451361868, Blast_Score=122, Evalue=6e-28,
Organism=Drosophila melanogaster, GI24648113, Length=234, Percent_Identity=38.4615384615385, Blast_Score=116, Evalue=4e-26,
Organism=Drosophila melanogaster, GI21356731, Length=535, Percent_Identity=26.5420560747664, Blast_Score=113, Evalue=4e-25,
Organism=Drosophila melanogaster, GI161078093, Length=510, Percent_Identity=23.5294117647059, Blast_Score=112, Evalue=5e-25,
Organism=Drosophila melanogaster, GI24652985, Length=257, Percent_Identity=34.6303501945525, Blast_Score=110, Evalue=2e-24,
Organism=Drosophila melanogaster, GI19922090, Length=257, Percent_Identity=34.6303501945525, Blast_Score=110, Evalue=2e-24,
Organism=Drosophila melanogaster, GI24652981, Length=257, Percent_Identity=34.6303501945525, Blast_Score=110, Evalue=2e-24,
Organism=Drosophila melanogaster, GI24652983, Length=257, Percent_Identity=34.6303501945525, Blast_Score=110, Evalue=2e-24,
Organism=Drosophila melanogaster, GI24648441, Length=179, Percent_Identity=36.8715083798883, Blast_Score=96, Evalue=6e-20,
Organism=Drosophila melanogaster, GI24648439, Length=179, Percent_Identity=36.8715083798883, Blast_Score=96, Evalue=6e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000120
- InterPro:   IPR020556 [H]

Pfam domain/function: PF01425 Amidase [H]

EC number: =3.5.1.4 [H]

Molecular weight: Translated: 59734; Mature: 59603

Theoretical pI: Translated: 9.51; Mature: 9.51

Prosite motif: PS00571 AMIDASES

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTRQTMNDTAPSSSTPQPTPQPGRRQWLSHLAGAAVTTVAAAAMTSRTASAAPAGTAPAA
CCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCC
SGPGTAGGGTPDPIVLMPAWQLSREIRGGRLSCRQVMNAYLAHIDRVNPVTNAIVALRDR
CCCCCCCCCCCCCEEEECCHHHHHHHCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
DALMQEAAAADEAFAARKVAGWMHGVPQAPKDLALTRGIRTTFGSPIFKDNVPTSDAIIV
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCHHHHH
ERVRKSGAILLGKTNTPEFGLGSQTFNPVYGPTRNPYDSTRTAGGSSGGAAAALAMRLLP
HHHHHCCCEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHC
VADGSDFGGSLRNPAGFCNVYGFRPSAGRVPYGPTPEVFIQQLGYEGPMGRTVADVALLL
CCCCCCCCCCCCCCCCCEEEECCCCCCCCCCCCCCHHHHHHHHCCCCCCCHHHHHHHHHH
ATQAGPDPRTPQALAPDPVLATLTPDNVMAALSTNLKGKRVAWLGDWDGYLPMEDGILQL
HHCCCCCCCCCCCCCCCCEEEEECCHHHHHHHHCCCCCCEEEEEECCCCCCCHHHHHHHH
CEQALQAFPAFGVGVDKIKPPFSPERLWKTWLVHRHFLVGNGMLPFYRDEAKRALLKPEA
HHHHHHHCCCCCCCHHHCCCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCHH
IWEIEGALKLSGADIYAASADRSAWYQAVEGVFAKFDYIAVPTAQVFPFDVRQPWPKEIA
HEEECCCEEECCCEEEEECCCHHHHHHHHHHHHHHCCEEECCCCCCCCCCCCCCCCHHHH
GRQMDTYHRWMEVVFPWTLSGCPAISVPVGFGKNGLPMGMQLIGRPRDDLSVLRLARAYE
CCHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCCCCHHHHHHCCCCHHHHHHHHHHHHH
QERDWVGRHLPRAVMA
HHHHHHHHHCHHHHCC
>Mature Secondary Structure 
TRQTMNDTAPSSSTPQPTPQPGRRQWLSHLAGAAVTTVAAAAMTSRTASAAPAGTAPAA
CCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCC
SGPGTAGGGTPDPIVLMPAWQLSREIRGGRLSCRQVMNAYLAHIDRVNPVTNAIVALRDR
CCCCCCCCCCCCCEEEECCHHHHHHHCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
DALMQEAAAADEAFAARKVAGWMHGVPQAPKDLALTRGIRTTFGSPIFKDNVPTSDAIIV
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCHHHHH
ERVRKSGAILLGKTNTPEFGLGSQTFNPVYGPTRNPYDSTRTAGGSSGGAAAALAMRLLP
HHHHHCCCEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHC
VADGSDFGGSLRNPAGFCNVYGFRPSAGRVPYGPTPEVFIQQLGYEGPMGRTVADVALLL
CCCCCCCCCCCCCCCCCEEEECCCCCCCCCCCCCCHHHHHHHHCCCCCCCHHHHHHHHHH
ATQAGPDPRTPQALAPDPVLATLTPDNVMAALSTNLKGKRVAWLGDWDGYLPMEDGILQL
HHCCCCCCCCCCCCCCCCEEEEECCHHHHHHHHCCCCCCEEEEEECCCCCCCHHHHHHHH
CEQALQAFPAFGVGVDKIKPPFSPERLWKTWLVHRHFLVGNGMLPFYRDEAKRALLKPEA
HHHHHHHCCCCCCCHHHCCCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCHH
IWEIEGALKLSGADIYAASADRSAWYQAVEGVFAKFDYIAVPTAQVFPFDVRQPWPKEIA
HEEECCCEEECCCEEEEECCCHHHHHHHHHHHHHHCCEEECCCCCCCCCCCCCCCCHHHH
GRQMDTYHRWMEVVFPWTLSGCPAISVPVGFGKNGLPMGMQLIGRPRDDLSVLRLARAYE
CCHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCCCCHHHHHHCCCCHHHHHHHHHHHHH
QERDWVGRHLPRAVMA
HHHHHHHHHCHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9389475 [H]