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The map label for this gene is rocF [H]

Identifier: 73537887

GI number: 73537887

Start: 693950

End: 694864

Strand: Direct

Name: rocF [H]

Synonym: Reut_B4054

Alternate gene names: 73537887

Gene position: 693950-694864 (Clockwise)

Preceding gene: 73537886

Following gene: 73537890

Centisome position: 25.46

GC content: 64.48

Gene sequence:

>915_bases
ATGAAGCCGATTACCCTGTTTGGCGCGCCGACGGATGTCGGCGCAAGCACCAGAGGCTGCACGATGGGCCCCGAAGCGCT
GCGCATTGCCGACATCGTCCCGGCGCTTGCGCGGATGGGGCTCGATGTCAGCGACGCCGGCAATATTGCTGGTCCGGTGA
ATCCGCTCGCGCCGCCGGTACAGGGCCTGCGCCATCTCGATGAGGTGGTGGCGTGGAATCGCGGCGTGTTCGAGGCCAGT
ACGCGCATTCTCCAGGCGGGCCGGATGCCGGTCCTGCTTGGCGGTGACCACTGCCTGGCGGTCGGATCGGTCAGTGCAGT
CGCCCGTCATTGCCGGGAGGCAGGCCGGAAGCTCGTCGTACTCTGGCTCGATGCCCATGCCGATGCCAATATCGGGACCA
GTACGCCGACCGGCAATATGCATGGCATGCCAGTGGCCTGCCTGTGCGGCGACGGCCCCACGCCACTGACCACGCTCGGC
GGCCAGCCGCCGGCGGTACGTCCCGAGGAAATCCGGCAAGTTGGCATCCGCAGCGTCGATGCGCAGGAAAAGCTGCGGCT
GCATGCGCTGGGCCTCAAGGTGTTCGATATGCGCTATATCGACGAGTACGGCATGCGCCAGACCATGGAGCAGGCGCTCG
CCGGCGTTGATGACGACACGCACCTGCACGTGAGCTTCGACGTCGATTTCATCGATTCGGCCATCGCGCCCGGCGTCGGT
ACGACGGTGCTGGGCGGACCCACGTATCGCGAGACACAACTCTGCATGGAAATGATCGCTGATACGGGACGATTGTCTTC
GCTGGACGTAATGGAGCTCAACCCTGCCTGCGATGTGCGTAATGAGACAGCACGGCTGGTGGTCGATTTCCTGGAAAGCC
TGTTTGGCAAGTCCACGCTACTGCGGGCGCGCTGA

Upstream 100 bases:

>100_bases
AACCTTGCGGCGTTACCCGGTGCCACACACGAGAAAGGTAGCGACATTCCGGCGTTCGCGCCGGTACAGCCGTCACCAAA
CATGCTCAGGAGGTCGCGCC

Downstream 100 bases:

>100_bases
CGGGCGCTCGCACGCCAAAAACTAAGGGGCGCCATGGTGGCGCCCCTTGTGCATCGGAAATGACTCGCTCAGGCGTGCAG
TGCCGCAGCAGCGGTGGACT

Product: arginase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 304; Mature: 304

Protein sequence:

>304_residues
MKPITLFGAPTDVGASTRGCTMGPEALRIADIVPALARMGLDVSDAGNIAGPVNPLAPPVQGLRHLDEVVAWNRGVFEAS
TRILQAGRMPVLLGGDHCLAVGSVSAVARHCREAGRKLVVLWLDAHADANIGTSTPTGNMHGMPVACLCGDGPTPLTTLG
GQPPAVRPEEIRQVGIRSVDAQEKLRLHALGLKVFDMRYIDEYGMRQTMEQALAGVDDDTHLHVSFDVDFIDSAIAPGVG
TTVLGGPTYRETQLCMEMIADTGRLSSLDVMELNPACDVRNETARLVVDFLESLFGKSTLLRAR

Sequences:

>Translated_304_residues
MKPITLFGAPTDVGASTRGCTMGPEALRIADIVPALARMGLDVSDAGNIAGPVNPLAPPVQGLRHLDEVVAWNRGVFEAS
TRILQAGRMPVLLGGDHCLAVGSVSAVARHCREAGRKLVVLWLDAHADANIGTSTPTGNMHGMPVACLCGDGPTPLTTLG
GQPPAVRPEEIRQVGIRSVDAQEKLRLHALGLKVFDMRYIDEYGMRQTMEQALAGVDDDTHLHVSFDVDFIDSAIAPGVG
TTVLGGPTYRETQLCMEMIADTGRLSSLDVMELNPACDVRNETARLVVDFLESLFGKSTLLRAR
>Mature_304_residues
MKPITLFGAPTDVGASTRGCTMGPEALRIADIVPALARMGLDVSDAGNIAGPVNPLAPPVQGLRHLDEVVAWNRGVFEAS
TRILQAGRMPVLLGGDHCLAVGSVSAVARHCREAGRKLVVLWLDAHADANIGTSTPTGNMHGMPVACLCGDGPTPLTTLG
GQPPAVRPEEIRQVGIRSVDAQEKLRLHALGLKVFDMRYIDEYGMRQTMEQALAGVDDDTHLHVSFDVDFIDSAIAPGVG
TTVLGGPTYRETQLCMEMIADTGRLSSLDVMELNPACDVRNETARLVVDFLESLFGKSTLLRAR

Specific function: Controls arginine catabolism [H]

COG id: COG0010

COG function: function code E; Arginase/agmatinase/formimionoglutamate hydrolase, arginase family

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the arginase family [H]

Homologues:

Organism=Homo sapiens, GI4502215, Length=305, Percent_Identity=35.0819672131148, Blast_Score=167, Evalue=1e-41,
Organism=Homo sapiens, GI10947139, Length=278, Percent_Identity=35.6115107913669, Blast_Score=159, Evalue=3e-39,
Organism=Caenorhabditis elegans, GI71996843, Length=224, Percent_Identity=30.8035714285714, Blast_Score=105, Evalue=2e-23,
Organism=Saccharomyces cerevisiae, GI6325146, Length=207, Percent_Identity=41.5458937198068, Blast_Score=155, Evalue=5e-39,
Organism=Drosophila melanogaster, GI24638886, Length=309, Percent_Identity=30.7443365695793, Blast_Score=150, Evalue=1e-36,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014033
- InterPro:   IPR006035
- InterPro:   IPR020855 [H]

Pfam domain/function: PF00491 Arginase [H]

EC number: =3.5.3.1 [H]

Molecular weight: Translated: 32384; Mature: 32384

Theoretical pI: Translated: 5.35; Mature: 5.35

Prosite motif: PS00147 ARGINASE_1 ; PS00148 ARGINASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
6.2 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
6.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKPITLFGAPTDVGASTRGCTMGPEALRIADIVPALARMGLDVSDAGNIAGPVNPLAPPV
CCCEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHH
QGLRHLDEVVAWNRGVFEASTRILQAGRMPVLLGGDHCLAVGSVSAVARHCREAGRKLVV
HHHHHHHHHHHHCCCHHHHHHHHHHCCCCEEEECCCCEEEHHHHHHHHHHHHHCCCEEEE
LWLDAHADANIGTSTPTGNMHGMPVACLCGDGPTPLTTLGGQPPAVRPEEIRQVGIRSVD
EEEECCCCCCCCCCCCCCCCCCCCEEEEECCCCCCCCCCCCCCCCCCHHHHHHHCCCCCC
AQEKLRLHALGLKVFDMRYIDEYGMRQTMEQALAGVDDDTHLHVSFDVDFIDSAIAPGVG
HHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEHHHHHHHHCCCCC
TTVLGGPTYRETQLCMEMIADTGRLSSLDVMELNPACDVRNETARLVVDFLESLFGKSTL
CEEECCCCCHHHHHHHHHHHCCCCCCCCEEEECCCCCCCCCHHHHHHHHHHHHHHCCCHH
LRAR
HCCC
>Mature Secondary Structure
MKPITLFGAPTDVGASTRGCTMGPEALRIADIVPALARMGLDVSDAGNIAGPVNPLAPPV
CCCEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHH
QGLRHLDEVVAWNRGVFEASTRILQAGRMPVLLGGDHCLAVGSVSAVARHCREAGRKLVV
HHHHHHHHHHHHCCCHHHHHHHHHHCCCCEEEECCCCEEEHHHHHHHHHHHHHCCCEEEE
LWLDAHADANIGTSTPTGNMHGMPVACLCGDGPTPLTTLGGQPPAVRPEEIRQVGIRSVD
EEEECCCCCCCCCCCCCCCCCCCCEEEEECCCCCCCCCCCCCCCCCCHHHHHHHCCCCCC
AQEKLRLHALGLKVFDMRYIDEYGMRQTMEQALAGVDDDTHLHVSFDVDFIDSAIAPGVG
HHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEHHHHHHHHCCCCC
TTVLGGPTYRETQLCMEMIADTGRLSSLDVMELNPACDVRNETARLVVDFLESLFGKSTL
CEEECCCCCHHHHHHHHHHHCCCCCCCCEEEECCCCCCCCCHHHHHHHHHHHHHHCCCHH
LRAR
HCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8647285; 10196128 [H]