Click here to switch to the map view.

The map label for this gene is crp [C]

Identifier: 73537878

GI number: 73537878

Start: 687868

End: 688650

Strand: Reverse

Name: crp [C]

Synonym: Reut_B4045

Alternate gene names: 73537878

Gene position: 688650-687868 (Counterclockwise)

Preceding gene: 73537880

Following gene: 73537877

Centisome position: 25.26

GC content: 70.11

Gene sequence:

>783_bases
ATGGGCATGGCTCAGCCCCCGGGCAGCGGGGCACGTGGCCCGTCAGGCATCCCGCGCGGCACACCGGGCGGCAACGCCGC
ACCGTCGCGCGCGGAGGCGGCCGCCACGCTGCAGGCGAGTGCCTGGTTTTCCCAGTTGCCGGGCCCACTGCGCGAGGCAC
TGCTGGACGATGGCACGTGGCGCCACCTCGCCGCCGGCGAGGCGCTGTTCGCGCGCGGCGATGCGTTTGACGGGCTTTAT
TGCGTTGCCAGCGGCACCATGCAGGTCGATGCCGCCGGCGAGTCCGGCAAGGCGGCGTTGCTCGGCCTGCTCGAAGCCGG
CGCCTGGTTCGGCGAGATCTGCCTGTTCGATGGCCTGCCACGCACTCACGACGCACGCGCGGTGCACGCCGCGCGGCTGT
GGCACGTCCCACGCGCGAGCCTCGAACGCCGGCTCGCTCAGCATCCCGCATGGTGGCGCGAGTTCGGCCTTCTGCTTGCG
GCCAAGACGCGGCTGGTCTTTGACTATGTCGAGGAAATGCAGCTGCTGCCGCCGGCCGCGCGCACGGCTCGTCGGCTGGC
AGCCATCGCGCGCGGCTATGGCAACCCGGCCCACGGCACGGACGATGCAACGCCTGCCGTTCAGGCCGTAAGGATTCCGC
AGGAACAGCTCGCGCAGATCCTCGGCCTGTCGCGGCAGACCGTCAATCAGGCGCTGCGCGAACTCGAATCGCGAGGGCTG
CTGCGGTTGCGGTATGGCAGCATCGAACTGCTCGATCTGACCGCACTCGAAATGCTCAACTGA

Upstream 100 bases:

>100_bases
TAGATTTATAGTATTGATCGCGTCCCGCGGCGTCTGTCTGATTTTTGACAGTCGGACGTGCTACGCCGTACGTATCAACC
CGAACACGACAGGAGACGAC

Downstream 100 bases:

>100_bases
ACTCGGTACGCGACATGATCACGCTTGACGCTCCCCGCCTGGACGCCTACCTCGCACGCCTTGGCCTCGACGCACCACCG
TCCCCCACGCTGGAATCCCT

Product: GntR family transcriptional regulator

Products: NA

Alternate protein names: Transcriptional Regulator Crp/Fnr Family; Transcriptional Regulator; CRP/FNR Family Transcriptional Regulator; Crp Family Transcriptional Regulator; Regulatory Protein; Transcription Regulator Protein; Crp/Fnr Family Transcriptional Regulator; Transcription Regulator Crp Family; GntR Family Transcriptional Regulator; Transcriptional Regulator Crp Family

Number of amino acids: Translated: 260; Mature: 259

Protein sequence:

>260_residues
MGMAQPPGSGARGPSGIPRGTPGGNAAPSRAEAAATLQASAWFSQLPGPLREALLDDGTWRHLAAGEALFARGDAFDGLY
CVASGTMQVDAAGESGKAALLGLLEAGAWFGEICLFDGLPRTHDARAVHAARLWHVPRASLERRLAQHPAWWREFGLLLA
AKTRLVFDYVEEMQLLPPAARTARRLAAIARGYGNPAHGTDDATPAVQAVRIPQEQLAQILGLSRQTVNQALRELESRGL
LRLRYGSIELLDLTALEMLN

Sequences:

>Translated_260_residues
MGMAQPPGSGARGPSGIPRGTPGGNAAPSRAEAAATLQASAWFSQLPGPLREALLDDGTWRHLAAGEALFARGDAFDGLY
CVASGTMQVDAAGESGKAALLGLLEAGAWFGEICLFDGLPRTHDARAVHAARLWHVPRASLERRLAQHPAWWREFGLLLA
AKTRLVFDYVEEMQLLPPAARTARRLAAIARGYGNPAHGTDDATPAVQAVRIPQEQLAQILGLSRQTVNQALRELESRGL
LRLRYGSIELLDLTALEMLN
>Mature_259_residues
GMAQPPGSGARGPSGIPRGTPGGNAAPSRAEAAATLQASAWFSQLPGPLREALLDDGTWRHLAAGEALFARGDAFDGLYC
VASGTMQVDAAGESGKAALLGLLEAGAWFGEICLFDGLPRTHDARAVHAARLWHVPRASLERRLAQHPAWWREFGLLLAA
KTRLVFDYVEEMQLLPPAARTARRLAAIARGYGNPAHGTDDATPAVQAVRIPQEQLAQILGLSRQTVNQALRELESRGLL
RLRYGSIELLDLTALEMLN

Specific function: This Protein Complexes With Cyclic AMP And Binds To Specific DNA Sites Near The Promoter To Regulate The Transcription Of Several Catabolite-Sensitive Operons. The Protein Induces A Severe Bend In The DNA. Acts As A Negative Regulator Of Its Own Synthesi

COG id: COG0664

COG function: function code T; cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 27826; Mature: 27695

Theoretical pI: Translated: 7.67; Mature: 7.67

Prosite motif: PS50042 CNMP_BINDING_3 ; PS51063 HTH_CRP_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGMAQPPGSGARGPSGIPRGTPGGNAAPSRAEAAATLQASAWFSQLPGPLREALLDDGTW
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCH
RHLAAGEALFARGDAFDGLYCVASGTMQVDAAGESGKAALLGLLEAGAWFGEICLFDGLP
HHHHCCCHHHCCCCCCCCEEEEECCCEEEECCCCCCHHHHHHHHHHCCHHHHHHHHCCCC
RTHDARAVHAARLWHVPRASLERRLAQHPAWWREFGLLLAAKTRLVFDYVEEMQLLPPAA
CCCCHHHHHHHHHHCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHH
RTARRLAAIARGYGNPAHGTDDATPAVQAVRIPQEQLAQILGLSRQTVNQALRELESRGL
HHHHHHHHHHHCCCCCCCCCCCCCHHHHHHCCCHHHHHHHHCCCHHHHHHHHHHHHHCCE
LRLRYGSIELLDLTALEMLN
EEEECCCEEEEHHHHHHHCC
>Mature Secondary Structure 
GMAQPPGSGARGPSGIPRGTPGGNAAPSRAEAAATLQASAWFSQLPGPLREALLDDGTW
CCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCH
RHLAAGEALFARGDAFDGLYCVASGTMQVDAAGESGKAALLGLLEAGAWFGEICLFDGLP
HHHHCCCHHHCCCCCCCCEEEEECCCEEEECCCCCCHHHHHHHHHHCCHHHHHHHHCCCC
RTHDARAVHAARLWHVPRASLERRLAQHPAWWREFGLLLAAKTRLVFDYVEEMQLLPPAA
CCCCHHHHHHHHHHCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHH
RTARRLAAIARGYGNPAHGTDDATPAVQAVRIPQEQLAQILGLSRQTVNQALRELESRGL
HHHHHHHHHHHCCCCCCCCCCCCCHHHHHHCCCHHHHHHHHCCCHHHHHHHHHHHHHCCE
LRLRYGSIELLDLTALEMLN
EEEECCCEEEEHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA