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The map label for this gene is czcC [H]

Identifier: 73537803

GI number: 73537803

Start: 606374

End: 607654

Strand: Reverse

Name: czcC [H]

Synonym: Reut_B3970

Alternate gene names: 73537803

Gene position: 607654-606374 (Counterclockwise)

Preceding gene: 73537804

Following gene: 73537802

Centisome position: 22.29

GC content: 69.01

Gene sequence:

>1281_bases
ATGAAACATGTAGTGATACCGCTGGGGCTGGCTTTCGTCTTGCTCGGCCCCGTTGCGCATGCCGCCACCGATGCGGCCAT
GCCGCCCGCCTTGCAGGACCAGCGCCCTGCACAACCACACGACGCCGCGGAGACGCGGGCCGTGCTGACTCTCGATACCG
CGCTGGCGCTTGCCATCGCCCGCAGCCCCACCCTTTCGGCTGCCCGACGGGAGCTCGATGCCACCGAAGGCGGCATCACG
CAAGCGCGCACGATCCCCAATCCGTCCGTCGGCTATGAGATGGAAGACACGCGGCGCGCATCGCGTACGACCACCGCGCA
AGTGAGCGTGCCGATCGAACTCGGCGGCAAACGCTCCGCTCGCATCGGCGCCGCACAGAAGGCGCGCGAGCTCGCCAGTG
CACAGTTCAGCAATGCCGAGTCGGACCTGCGCGCCACCGTGATTGGCGCGTTTTTCCAGGTGCTGGTGGCGCAAGAACGT
GTCAGCCTGGCGGAGAGTTCGGTCGGCATCGCCACGCGCGGCACGCAGGCCGCGGCAAGGCGCGTGGCGGCCGGCAAGGT
CTCGCCCGTGGAGCAGACCCGCGCCGAGGTCGAACAGGCCAATGCCGAACTCGAACTGGCCGAGGCGCGCGCCACGCTCG
ACGCGGCCCGCCAGCAGCTGGCCGCCCAATGGGGCAGCCAGCTGCCGGTGTTCGCGTCGGCAAGCGGCGACCTGGAGGCA
CTGCCGTCGCGGCCCCTGCCCAATGTCCTCGATGAAGCGCTCGATACCGCCCCGGAGATGCGCGCGAGCCAGAGCGAAAT
GGCACGGCGCCAGGCGATAGTCAACGTAGAACGCAGCCGCCAGTACCCCGACGTGACCGTGAGTGTCGGCGCCAAGCGCG
AATATTCGTCGGACCGCGGGTACTACCCGGTGCTCGGCATCTCGCTTCCCTTGCCGCTGTTCGACCGCAACCAGGGCAAC
CTGTACACGGCGATCCGGCAGGCCGACAAGGCCGCCGACGAATCGCGCGCCACGCGCGTACGGCTGGCCAGTGACCTGCG
CCAGGCCTCGAACCAGCTCGCGCTGTCTCGCAATAGCGCGCTGACGTTACGTCAGACCGTGCTGCCTGCCGCGCAGCGTG
CGTACCAGGCCGCGTCGCAAGGATTCGAAGCTGGCAAGTTCGCCTATCTCGAAGTGCTGGACGCCCAGCGCACGCTGCTG
CAGGCACGGGTGCGCTATCTCGGGGCCGTGGCCGCGACCTACCAGGCCGCCACGGCCATCGACCGCATGCTCGGCCGCTG
A

Upstream 100 bases:

>100_bases
CCCGGATCGACGGATCTCGCGGCGTGATTGCCGTCGGGGCGCGCACGCGCTTCTGACGCGGTCTCGCCGGTGTTCCTGGT
CTTCGATCCGGTGATACCCG

Downstream 100 bases:

>100_bases
GCGGCTACCAAGGATTCCCATGGCAATCACCAAGACCCAACGCAACGCGATCGTTGCCATCATCGGCGTCGGCGTGCTGG
CTGGCGCCGCACTACTCTTC

Product: Outer membrane efflux protein

Products: NA

Alternate protein names: Cation efflux system protein CzcC [H]

Number of amino acids: Translated: 426; Mature: 426

Protein sequence:

>426_residues
MKHVVIPLGLAFVLLGPVAHAATDAAMPPALQDQRPAQPHDAAETRAVLTLDTALALAIARSPTLSAARRELDATEGGIT
QARTIPNPSVGYEMEDTRRASRTTTAQVSVPIELGGKRSARIGAAQKARELASAQFSNAESDLRATVIGAFFQVLVAQER
VSLAESSVGIATRGTQAAARRVAAGKVSPVEQTRAEVEQANAELELAEARATLDAARQQLAAQWGSQLPVFASASGDLEA
LPSRPLPNVLDEALDTAPEMRASQSEMARRQAIVNVERSRQYPDVTVSVGAKREYSSDRGYYPVLGISLPLPLFDRNQGN
LYTAIRQADKAADESRATRVRLASDLRQASNQLALSRNSALTLRQTVLPAAQRAYQAASQGFEAGKFAYLEVLDAQRTLL
QARVRYLGAVAATYQAATAIDRMLGR

Sequences:

>Translated_426_residues
MKHVVIPLGLAFVLLGPVAHAATDAAMPPALQDQRPAQPHDAAETRAVLTLDTALALAIARSPTLSAARRELDATEGGIT
QARTIPNPSVGYEMEDTRRASRTTTAQVSVPIELGGKRSARIGAAQKARELASAQFSNAESDLRATVIGAFFQVLVAQER
VSLAESSVGIATRGTQAAARRVAAGKVSPVEQTRAEVEQANAELELAEARATLDAARQQLAAQWGSQLPVFASASGDLEA
LPSRPLPNVLDEALDTAPEMRASQSEMARRQAIVNVERSRQYPDVTVSVGAKREYSSDRGYYPVLGISLPLPLFDRNQGN
LYTAIRQADKAADESRATRVRLASDLRQASNQLALSRNSALTLRQTVLPAAQRAYQAASQGFEAGKFAYLEVLDAQRTLL
QARVRYLGAVAATYQAATAIDRMLGR
>Mature_426_residues
MKHVVIPLGLAFVLLGPVAHAATDAAMPPALQDQRPAQPHDAAETRAVLTLDTALALAIARSPTLSAARRELDATEGGIT
QARTIPNPSVGYEMEDTRRASRTTTAQVSVPIELGGKRSARIGAAQKARELASAQFSNAESDLRATVIGAFFQVLVAQER
VSLAESSVGIATRGTQAAARRVAAGKVSPVEQTRAEVEQANAELELAEARATLDAARQQLAAQWGSQLPVFASASGDLEA
LPSRPLPNVLDEALDTAPEMRASQSEMARRQAIVNVERSRQYPDVTVSVGAKREYSSDRGYYPVLGISLPLPLFDRNQGN
LYTAIRQADKAADESRATRVRLASDLRQASNQLALSRNSALTLRQTVLPAAQRAYQAASQGFEAGKFAYLEVLDAQRTLL
QARVRYLGAVAATYQAATAIDRMLGR

Specific function: CzcC protein appears to modify the specificity of the system, perhaps by acting on the CzcB protein. When the CzcC protein is added to CzcA and CzcB, the efflux system gains specificity for cadmium and cobalt [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell outer membrane (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003423 [H]

Pfam domain/function: PF02321 OEP [H]

EC number: NA

Molecular weight: Translated: 45559; Mature: 45559

Theoretical pI: Translated: 9.80; Mature: 9.80

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKHVVIPLGLAFVLLGPVAHAATDAAMPPALQDQRPAQPHDAAETRAVLTLDTALALAIA
CCEEEEHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHCCEEEEHHHHHHHHHH
RSPTLSAARRELDATEGGITQARTIPNPSVGYEMEDTRRASRTTTAQVSVPIELGGKRSA
CCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHCCCEEEEEEEEEECCCCCH
RIGAAQKARELASAQFSNAESDLRATVIGAFFQVLVAQERVSLAESSVGIATRGTQAAAR
HHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEECCHHHHHH
RVAAGKVSPVEQTRAEVEQANAELELAEARATLDAARQQLAAQWGSQLPVFASASGDLEA
HHHCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCCHHH
LPSRPLPNVLDEALDTAPEMRASQSEMARRQAIVNVERSRQYPDVTVSVGAKREYSSDRG
CCCCCCHHHHHHHHHCCHHHHCCHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCC
YYPVLGISLPLPLFDRNQGNLYTAIRQADKAADESRATRVRLASDLRQASNQLALSRNSA
CCEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
LTLRQTVLPAAQRAYQAASQGFEAGKFAYLEVLDAQRTLLQARVRYLGAVAATYQAATAI
HHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DRMLGR
HHHHCC
>Mature Secondary Structure
MKHVVIPLGLAFVLLGPVAHAATDAAMPPALQDQRPAQPHDAAETRAVLTLDTALALAIA
CCEEEEHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHCCEEEEHHHHHHHHHH
RSPTLSAARRELDATEGGITQARTIPNPSVGYEMEDTRRASRTTTAQVSVPIELGGKRSA
CCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHCCCEEEEEEEEEECCCCCH
RIGAAQKARELASAQFSNAESDLRATVIGAFFQVLVAQERVSLAESSVGIATRGTQAAAR
HHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEECCHHHHHH
RVAAGKVSPVEQTRAEVEQANAELELAEARATLDAARQQLAAQWGSQLPVFASASGDLEA
HHHCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCCHHH
LPSRPLPNVLDEALDTAPEMRASQSEMARRQAIVNVERSRQYPDVTVSVGAKREYSSDRG
CCCCCCHHHHHHHHHCCHHHHCCHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCC
YYPVLGISLPLPLFDRNQGNLYTAIRQADKAADESRATRVRLASDLRQASNQLALSRNSA
CCEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
LTLRQTVLPAAQRAYQAASQGFEAGKFAYLEVLDAQRTLLQARVRYLGAVAATYQAATAI
HHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DRMLGR
HHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2678100; 7766206 [H]