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The map label for this gene is czcB [H]

Identifier: 73537802

GI number: 73537802

Start: 605131

End: 606354

Strand: Reverse

Name: czcB [H]

Synonym: Reut_B3969

Alternate gene names: 73537802

Gene position: 606354-605131 (Counterclockwise)

Preceding gene: 73537803

Following gene: 73537801

Centisome position: 22.24

GC content: 66.58

Gene sequence:

>1224_bases
ATGGCAATCACCAAGACCCAACGCAACGCGATCGTTGCCATCATCGGCGTCGGCGTGCTGGCTGGCGCCGCACTACTCTT
CAGCGGCCGTGGTCCCGGCGACGACCACGATCACGGCGAACACGCCGCGGAGCCGAGCAGCAACGAAAGTGGAAAGGAAG
ACAAGGCCACCGCATCGGCCAACGACGCGCATGCCGCCGACCGCATCGCCATGACGCCCGAGCAGATCCGCAGCGCCGGA
CTGGAATTGCACACAGCCGGCCCCGGCCGCGTGCAGGCCGCCGTGCAGTTTCCCGGCGAAATCCGCTTCAATGAAGACCG
CACCGCCCACGTCGTGCCGCGCGTGGTCGGCGTAGCCGAGTCCGTGCCGGCCGTGCTGGGTCAGCGCGTGAAGAAGGGAG
AACTGCTTGCGGTACTGGCCAGTACACAGCTTTCGGATCAGCGCAGCGAACTGCTGGCTGCGCAGAAGCGGCTGGAACTC
GCCCGCACGACCTATACGCGCGAGAAGCGCCTGTGGGAGGACAAGATCTCGGCCGAACAGGATTTTCTGGCCGCGCGCAC
CGCGCTGCAGGAAGCCGAGATCGCGGTGCGGAACGCGACCCAGAAGCTCACCGCAATCGGCGCCCGGCCGGCGTCGGCCG
GACTCAACAAGTTCGAGTTGCGCGCGCCGTTCGACGGCATCGTCGTCGAAAAGCACCTCGCACTCGGCGAAGCGGTAGCG
GCGGACACGACCGTCTTTACGATTTCCGATCTCGCCACCGTGTGGGCTGAGTTCGTGATCGCGCCGAAGGACCTGAGCCA
GGTACGGCTCGGCGAGAAAGTCAGCATCGCTTCCACCGCGTTCGACGGCACTGCCACGGGCACCGTGTCCTACGTGGGCT
CGCTGCTCGGCCAGCAGACACGCACCGCGACCGCGCGCGTAACGCTGTCGAACCCGGACATGGCATGGCGCCCCGGCCTC
TTCGTTACGGTCAGCGTGGCCGGACAGGAAACCGAAGTCCCCGTCGTCGTCGAAAGCGAAGCCGTGCAGACTGAAAGCAG
CCAGCCAATGGTCTATGTCGAGGTCCCAGGCGGCTTTGAGGCGCGCCCGGTCGCCACGGGACGCAGCGACGGCAAACGGA
TCGAGATCGTCAAGGGGCTGGAGCCAGGCGCACGCTACGTCGCACGCAACAGTTTCGTGCTGAAGGCCGAGCAAGGCAAG
GCCGGCGCCGAGCACGCCCACTGA

Upstream 100 bases:

>100_bases
CAGGCACGGGTGCGCTATCTCGGGGCCGTGGCCGCGACCTACCAGGCCGCCACGGCCATCGACCGCATGCTCGGCCGCTG
AGCGGCTACCAAGGATTCCC

Downstream 100 bases:

>100_bases
TCCGCAGGAGCTGACCATGTTCGAACGCATCATCCGCTTTGCCATCGAGCAGCGCTGGCTGGTCCTGCTGGCAGTGCTTG
GCATAGCGCTGCTGGGCCTC

Product: secretion protein HlyD

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 407; Mature: 406

Protein sequence:

>407_residues
MAITKTQRNAIVAIIGVGVLAGAALLFSGRGPGDDHDHGEHAAEPSSNESGKEDKATASANDAHAADRIAMTPEQIRSAG
LELHTAGPGRVQAAVQFPGEIRFNEDRTAHVVPRVVGVAESVPAVLGQRVKKGELLAVLASTQLSDQRSELLAAQKRLEL
ARTTYTREKRLWEDKISAEQDFLAARTALQEAEIAVRNATQKLTAIGARPASAGLNKFELRAPFDGIVVEKHLALGEAVA
ADTTVFTISDLATVWAEFVIAPKDLSQVRLGEKVSIASTAFDGTATGTVSYVGSLLGQQTRTATARVTLSNPDMAWRPGL
FVTVSVAGQETEVPVVVESEAVQTESSQPMVYVEVPGGFEARPVATGRSDGKRIEIVKGLEPGARYVARNSFVLKAEQGK
AGAEHAH

Sequences:

>Translated_407_residues
MAITKTQRNAIVAIIGVGVLAGAALLFSGRGPGDDHDHGEHAAEPSSNESGKEDKATASANDAHAADRIAMTPEQIRSAG
LELHTAGPGRVQAAVQFPGEIRFNEDRTAHVVPRVVGVAESVPAVLGQRVKKGELLAVLASTQLSDQRSELLAAQKRLEL
ARTTYTREKRLWEDKISAEQDFLAARTALQEAEIAVRNATQKLTAIGARPASAGLNKFELRAPFDGIVVEKHLALGEAVA
ADTTVFTISDLATVWAEFVIAPKDLSQVRLGEKVSIASTAFDGTATGTVSYVGSLLGQQTRTATARVTLSNPDMAWRPGL
FVTVSVAGQETEVPVVVESEAVQTESSQPMVYVEVPGGFEARPVATGRSDGKRIEIVKGLEPGARYVARNSFVLKAEQGK
AGAEHAH
>Mature_406_residues
AITKTQRNAIVAIIGVGVLAGAALLFSGRGPGDDHDHGEHAAEPSSNESGKEDKATASANDAHAADRIAMTPEQIRSAGL
ELHTAGPGRVQAAVQFPGEIRFNEDRTAHVVPRVVGVAESVPAVLGQRVKKGELLAVLASTQLSDQRSELLAAQKRLELA
RTTYTREKRLWEDKISAEQDFLAARTALQEAEIAVRNATQKLTAIGARPASAGLNKFELRAPFDGIVVEKHLALGEAVAA
DTTVFTISDLATVWAEFVIAPKDLSQVRLGEKVSIASTAFDGTATGTVSYVGSLLGQQTRTATARVTLSNPDMAWRPGLF
VTVSVAGQETEVPVVVESEAVQTESSQPMVYVEVPGGFEARPVATGRSDGKRIEIVKGLEPGARYVARNSFVLKAEQGKA
GAEHAH

Specific function: CzcA and CzcB together would act in zinc efflux nearly as effectively as the complete czc efflux system (CzcABC). The CzcB protein is thought to funnel zinc cations to the CzcA transport protein [H]

COG id: COG0845

COG function: function code M; Membrane-fusion protein

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family [H]

Homologues:

Organism=Escherichia coli, GI1786787, Length=377, Percent_Identity=24.6684350132626, Blast_Score=73, Evalue=4e-14,
Organism=Escherichia coli, GI1789929, Length=353, Percent_Identity=22.0963172804533, Blast_Score=62, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005695
- InterPro:   IPR006143 [H]

Pfam domain/function: PF00529 HlyD [H]

EC number: NA

Molecular weight: Translated: 43077; Mature: 42946

Theoretical pI: Translated: 6.26; Mature: 6.26

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
0.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAITKTQRNAIVAIIGVGVLAGAALLFSGRGPGDDHDHGEHAAEPSSNESGKEDKATASA
CCCCCCCCCEEEEEEHHHHHHHHHHEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
NDAHAADRIAMTPEQIRSAGLELHTAGPGRVQAAVQFPGEIRFNEDRTAHVVPRVVGVAE
CCCHHHHHHCCCHHHHHHCCCEEEECCCCEEEEEEECCCEEEECCCCCHHHHHHHHHHHH
SVPAVLGQRVKKGELLAVLASTQLSDQRSELLAAQKRLELARTTYTREKRLWEDKISAEQ
HHHHHHHHHCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHH
DFLAARTALQEAEIAVRNATQKLTAIGARPASAGLNKFELRAPFDGIVVEKHLALGEAVA
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHCCCCEEEEECCCCCEEEEHHHHHHHHHH
ADTTVFTISDLATVWAEFVIAPKDLSQVRLGEKVSIASTAFDGTATGTVSYVGSLLGQQT
CCCEEEEHHHHHHHHHHHEECCCCHHHHHCCCEEEEEEECCCCCCCHHHHHHHHHHCCCC
RTATARVTLSNPDMAWRPGLFVTVSVAGQETEVPVVVESEAVQTESSQPMVYVEVPGGFE
CCEEEEEEECCCCCCCCCCEEEEEEECCCCCCCCEEECCCHHCCCCCCCEEEEECCCCCC
ARPVATGRSDGKRIEIVKGLEPGARYVARNSFVLKAEQGKAGAEHAH
CCEECCCCCCCCEEEEEECCCCCHHHEECCCEEEEECCCCCCCCCCC
>Mature Secondary Structure 
AITKTQRNAIVAIIGVGVLAGAALLFSGRGPGDDHDHGEHAAEPSSNESGKEDKATASA
CCCCCCCCEEEEEEHHHHHHHHHHEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
NDAHAADRIAMTPEQIRSAGLELHTAGPGRVQAAVQFPGEIRFNEDRTAHVVPRVVGVAE
CCCHHHHHHCCCHHHHHHCCCEEEECCCCEEEEEEECCCEEEECCCCCHHHHHHHHHHHH
SVPAVLGQRVKKGELLAVLASTQLSDQRSELLAAQKRLELARTTYTREKRLWEDKISAEQ
HHHHHHHHHCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHH
DFLAARTALQEAEIAVRNATQKLTAIGARPASAGLNKFELRAPFDGIVVEKHLALGEAVA
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHCCCCEEEEECCCCCEEEEHHHHHHHHHH
ADTTVFTISDLATVWAEFVIAPKDLSQVRLGEKVSIASTAFDGTATGTVSYVGSLLGQQT
CCCEEEEHHHHHHHHHHHEECCCCHHHHHCCCEEEEEEECCCCCCCHHHHHHHHHHCCCC
RTATARVTLSNPDMAWRPGLFVTVSVAGQETEVPVVVESEAVQTESSQPMVYVEVPGGFE
CCEEEEEEECCCCCCCCCCEEEEEEECCCCCCCCEEECCCHHCCCCCCCEEEEECCCCCC
ARPVATGRSDGKRIEIVKGLEPGARYVARNSFVLKAEQGKAGAEHAH
CCEECCCCCCCCEEEEEECCCCCHHHEECCCEEEEECCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8829543 [H]