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The map label for this gene is fabF [H]

Identifier: 73537761

GI number: 73537761

Start: 558429

End: 559679

Strand: Reverse

Name: fabF [H]

Synonym: Reut_B3927

Alternate gene names: 73537761

Gene position: 559679-558429 (Counterclockwise)

Preceding gene: 73537762

Following gene: 73537760

Centisome position: 20.53

GC content: 66.83

Gene sequence:

>1251_bases
ATGCGGCTTGATACAATGGCCGCACCCCGCGTCTCCCACTCAACACATTCCGTGTCGCCGCTCCATCTTTCGCATTTCAC
TGCCACCAGTTGCATCGGCACCGGGCTTGACGACACGGTGAGCGCACTGCGGGAACAGCGCGGCGGCCTCGCGCCGTGCC
AGTTCGGTGATATCCGGCTCGATACCTGGGTCGGCGAAGTGCCGGGCGTCGACAGCGTCACCCTGCCGCCGGGATTGGCG
GATTTTGCCTGCCGCAACAATAGCCTGGCCCTGCTCGCGCTGGAACAGGATGGCTTCGCCGACCGGGTACGCGAGGCGGT
GGCACGCTACGGCGCGGACCGCATCGGCGTATTCCTCGGCACCAGCACGGCGGGCGTGCTGCAGACTGAACTTGCCTACC
GGCAACGCGATCCGCAAACGGGCGCGTTGCCTGCAGGCCTCAGCTATGCCGGTACCCACAGTCCGTATTCGCTGCCGGGC
TTCGTACGCGCGTATTTTGGCTTGCAGGGCCCGGCCAACGCGGTGTCGTCGGCGTGTTCATCCGGCGCAAAAGTATTCAC
GTCGGCGCGCCGCCTGATTGAAGCCGGACTGATCGATGCAGCCGTCGTCGGCGGCGTGGACTCGTTGTGCCACACCACGC
TGTATGGCTTCGGCTCGCTCGAATTGCTCTCCAACCAGCCATGCCGGCCATTCGATGCCGATCGCAACGGCATCTCGATC
GGTGAGGCCGCCGCCTTTGTGCTGGTCGAGCGCACGCCCGATCCCGCACCGGACGGTGCGATCCTGCTGCTTGGCATCGG
CGAGTCGAGCGACGCACACCATATGTCGGCACCGCACCCGGAAGGCCTGGGCGCCAGCATGGCCATGGAGCAGGCGCTGA
CCCGTGCCGGCGTGTCGCCGGAACAGGTCGATTACGTGAACCTGCACGGTACCGCCACGCGCGCCAATGACGCCACGGAA
GCGCGCGCGATCTCGGCATTGCTGCCGGGCACGCCATGCAGTTCCACCAAGGGCGCCACGGGGCATACGCTTGGCGCCGC
GGGCGCACTCGAAGCGGTGATCAGCGCACTGGCCCTGCGCCACGGGCTGCTGCCGGCTGGCATCAACACCACGCAGATCG
ATCCCGCGCTTGCGGTGGACTACTGCCTTGCAACGCGCGAACAGCCGCTGCGCCATGTGCTCAGCAATGCGTTCGGCTTC
GGCGGTTCCAACTGCAGCCTGCTGCTGGGCCGCGCAACGGGCGCGCAATGA

Upstream 100 bases:

>100_bases
CCGCACTGCACGACCGTGCTGCCCAAACTGCTTGCAACAATTACCGACGCGGGCCTGCGCTGCGTGACGCTGCGTGCCGG
CATGGCGGCATGGGACTTGC

Downstream 100 bases:

>100_bases
CCATGCGCACACCGCTTATCGCTTTCATCGATGGCATCGGGGTGCTCGGCCCGGGGTTGAGCGGCTGGGCACAGGCCAAC
GAGGTGCTTGCCGGACGGCA

Product: 3-oxoacyl-(acyl carrier protein) synthase I

Products: NA

Alternate protein names: 3-oxoacyl-[acyl-carrier-protein] synthase II; Beta-ketoacyl-ACP synthase II; KAS II [H]

Number of amino acids: Translated: 416; Mature: 416

Protein sequence:

>416_residues
MRLDTMAAPRVSHSTHSVSPLHLSHFTATSCIGTGLDDTVSALREQRGGLAPCQFGDIRLDTWVGEVPGVDSVTLPPGLA
DFACRNNSLALLALEQDGFADRVREAVARYGADRIGVFLGTSTAGVLQTELAYRQRDPQTGALPAGLSYAGTHSPYSLPG
FVRAYFGLQGPANAVSSACSSGAKVFTSARRLIEAGLIDAAVVGGVDSLCHTTLYGFGSLELLSNQPCRPFDADRNGISI
GEAAAFVLVERTPDPAPDGAILLLGIGESSDAHHMSAPHPEGLGASMAMEQALTRAGVSPEQVDYVNLHGTATRANDATE
ARAISALLPGTPCSSTKGATGHTLGAAGALEAVISALALRHGLLPAGINTTQIDPALAVDYCLATREQPLRHVLSNAFGF
GGSNCSLLLGRATGAQ

Sequences:

>Translated_416_residues
MRLDTMAAPRVSHSTHSVSPLHLSHFTATSCIGTGLDDTVSALREQRGGLAPCQFGDIRLDTWVGEVPGVDSVTLPPGLA
DFACRNNSLALLALEQDGFADRVREAVARYGADRIGVFLGTSTAGVLQTELAYRQRDPQTGALPAGLSYAGTHSPYSLPG
FVRAYFGLQGPANAVSSACSSGAKVFTSARRLIEAGLIDAAVVGGVDSLCHTTLYGFGSLELLSNQPCRPFDADRNGISI
GEAAAFVLVERTPDPAPDGAILLLGIGESSDAHHMSAPHPEGLGASMAMEQALTRAGVSPEQVDYVNLHGTATRANDATE
ARAISALLPGTPCSSTKGATGHTLGAAGALEAVISALALRHGLLPAGINTTQIDPALAVDYCLATREQPLRHVLSNAFGF
GGSNCSLLLGRATGAQ
>Mature_416_residues
MRLDTMAAPRVSHSTHSVSPLHLSHFTATSCIGTGLDDTVSALREQRGGLAPCQFGDIRLDTWVGEVPGVDSVTLPPGLA
DFACRNNSLALLALEQDGFADRVREAVARYGADRIGVFLGTSTAGVLQTELAYRQRDPQTGALPAGLSYAGTHSPYSLPG
FVRAYFGLQGPANAVSSACSSGAKVFTSARRLIEAGLIDAAVVGGVDSLCHTTLYGFGSLELLSNQPCRPFDADRNGISI
GEAAAFVLVERTPDPAPDGAILLLGIGESSDAHHMSAPHPEGLGASMAMEQALTRAGVSPEQVDYVNLHGTATRANDATE
ARAISALLPGTPCSSTKGATGHTLGAAGALEAVISALALRHGLLPAGINTTQIDPALAVDYCLATREQPLRHVLSNAFGF
GGSNCSLLLGRATGAQ

Specific function: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Has a preference for short chain acid substrates [H]

COG id: COG0304

COG function: function code IQ; 3-oxoacyl-(acyl-carrier-protein) synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the beta-ketoacyl-ACP synthases family [H]

Homologues:

Organism=Homo sapiens, GI8923559, Length=281, Percent_Identity=38.7900355871886, Blast_Score=159, Evalue=4e-39,
Organism=Homo sapiens, GI223972627, Length=147, Percent_Identity=44.2176870748299, Blast_Score=107, Evalue=3e-23,
Organism=Homo sapiens, GI41872631, Length=276, Percent_Identity=30.4347826086957, Blast_Score=91, Evalue=2e-18,
Organism=Escherichia coli, GI1787337, Length=283, Percent_Identity=34.6289752650177, Blast_Score=143, Evalue=2e-35,
Organism=Escherichia coli, GI1788663, Length=409, Percent_Identity=29.5843520782396, Blast_Score=127, Evalue=2e-30,
Organism=Caenorhabditis elegans, GI71983541, Length=280, Percent_Identity=33.2142857142857, Blast_Score=142, Evalue=3e-34,
Organism=Caenorhabditis elegans, GI71983535, Length=258, Percent_Identity=33.7209302325581, Blast_Score=134, Evalue=7e-32,
Organism=Caenorhabditis elegans, GI212642053, Length=394, Percent_Identity=27.9187817258883, Blast_Score=98, Evalue=6e-21,
Organism=Caenorhabditis elegans, GI17550940, Length=301, Percent_Identity=25.5813953488372, Blast_Score=95, Evalue=6e-20,
Organism=Saccharomyces cerevisiae, GI6320904, Length=336, Percent_Identity=32.4404761904762, Blast_Score=145, Evalue=8e-36,
Organism=Drosophila melanogaster, GI24644341, Length=288, Percent_Identity=37.8472222222222, Blast_Score=158, Evalue=6e-39,
Organism=Drosophila melanogaster, GI24581345, Length=283, Percent_Identity=26.8551236749117, Blast_Score=84, Evalue=2e-16,
Organism=Drosophila melanogaster, GI19920632, Length=276, Percent_Identity=26.4492753623188, Blast_Score=81, Evalue=1e-15,
Organism=Drosophila melanogaster, GI221330659, Length=276, Percent_Identity=26.4492753623188, Blast_Score=81, Evalue=2e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017568
- InterPro:   IPR000794
- InterPro:   IPR018201
- InterPro:   IPR014031
- InterPro:   IPR014030
- InterPro:   IPR016039
- InterPro:   IPR016038 [H]

Pfam domain/function: PF00109 ketoacyl-synt; PF02801 Ketoacyl-synt_C [H]

EC number: =2.3.1.179 [H]

Molecular weight: Translated: 42892; Mature: 42892

Theoretical pI: Translated: 5.87; Mature: 5.87

Prosite motif: PS00013 PROKAR_LIPOPROTEIN ; PS00606 B_KETOACYL_SYNTHASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRLDTMAAPRVSHSTHSVSPLHLSHFTATSCIGTGLDDTVSALREQRGGLAPCQFGDIRL
CCCCCCCCCCCCCCCCCCCCEEHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCCCEEE
DTWVGEVPGVDSVTLPPGLADFACRNNSLALLALEQDGFADRVREAVARYGADRIGVFLG
EEECCCCCCCCCEECCCCCHHHHCCCCCEEEEEECCCCHHHHHHHHHHHHCCCCEEEEEC
TSTAGVLQTELAYRQRDPQTGALPAGLSYAGTHSPYSLPGFVRAYFGLQGPANAVSSACS
CCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHCCCCHHHHHHHHHH
SGAKVFTSARRLIEAGLIDAAVVGGVDSLCHTTLYGFGSLELLSNQPCRPFDADRNGISI
CCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCHHHCCCCCCCCCCCCCCCCC
GEAAAFVLVERTPDPAPDGAILLLGIGESSDAHHMSAPHPEGLGASMAMEQALTRAGVSP
CCEEEEEEEECCCCCCCCCEEEEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCH
EQVDYVNLHGTATRANDATEARAISALLPGTPCSSTKGATGHTLGAAGALEAVISALALR
HHEEEEEECCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHH
HGLLPAGINTTQIDPALAVDYCLATREQPLRHVLSNAFGFGGSNCSLLLGRATGAQ
HCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCC
>Mature Secondary Structure
MRLDTMAAPRVSHSTHSVSPLHLSHFTATSCIGTGLDDTVSALREQRGGLAPCQFGDIRL
CCCCCCCCCCCCCCCCCCCCEEHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCCCEEE
DTWVGEVPGVDSVTLPPGLADFACRNNSLALLALEQDGFADRVREAVARYGADRIGVFLG
EEECCCCCCCCCEECCCCCHHHHCCCCCEEEEEECCCCHHHHHHHHHHHHCCCCEEEEEC
TSTAGVLQTELAYRQRDPQTGALPAGLSYAGTHSPYSLPGFVRAYFGLQGPANAVSSACS
CCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHCCCCHHHHHHHHHH
SGAKVFTSARRLIEAGLIDAAVVGGVDSLCHTTLYGFGSLELLSNQPCRPFDADRNGISI
CCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCHHHCCCCCCCCCCCCCCCCC
GEAAAFVLVERTPDPAPDGAILLLGIGESSDAHHMSAPHPEGLGASMAMEQALTRAGVSP
CCEEEEEEEECCCCCCCCCEEEEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCH
EQVDYVNLHGTATRANDATEARAISALLPGTPCSSTKGATGHTLGAAGALEAVISALALR
HHEEEEEECCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHH
HGLLPAGINTTQIDPALAVDYCLATREQPLRHVLSNAFGFGGSNCSLLLGRATGAQ
HCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8905231; 11152607 [H]