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The map label for this gene is pyc [H]

Identifier: 73537726

GI number: 73537726

Start: 516030

End: 519347

Strand: Direct

Name: pyc [H]

Synonym: Reut_B3892

Alternate gene names: 73537726

Gene position: 516030-519347 (Clockwise)

Preceding gene: 73537725

Following gene: 73537727

Centisome position: 18.93

GC content: 67.33

Gene sequence:

>3318_bases
TTGAACAAGCTGTTGATCGCCAATCGGGGCGAGATTGCCTTGCGCGTGCTGCGCGCGGCACGCGACCTGGATATCGCCAC
GGTGGCCGTGTATTCGCAGGACGACGCCAGCTCGCGGCATCGTATGCTGGCTGACGAGGCGATTGCCCTCGACGGCTCAG
GGCCGGCCGCCTATATCGACATTGCGGGAATCATCACCGCCGCGAAGGCATCCGGTTGCGATGCGATCCACCCGGGCTAT
GGCTTCCTGAGCGAGCGCGCTGATTTTGCGCAGGCGTGCGCCGACGCCGGCATCCGGTTCATCGGGCCGACGGTCGAACA
GCTTGCGTTGTTTGGCGACAAGGGAAGGGCGCTTGAGCTGGCGATGGAAAGCGATGTGCGCGTCATGCCCGCCACGCGCG
GCGGTGCTTCGCTCGAAGACATCACGAGCTTCTTCGACAAGCAGGGCGATGCCGGCGTGGTGATCAAGGCCGTTGGCGGC
GGCGGTGGCCGCGGCATGCGCGTGGTCAGGCGGCGCGAAGACCTGGCCGAAGCGTATGCGCGCTGCCGGTCGGAGGCAGC
TTCCGCGTTCGGCGTCGATGCGCTGTACGCCGAACGGCTAGTGAGCCGCGCGCGCCATATCGAAGTGCAGATCGCCGGCG
ACGGCACCCATGTCGTCGCGCTGGGCGAGCGTGACTGCACCTTGCAGCGCCGCTTCCAGAAACTCGTGGAGATCGCGCCG
AGCCCCGTGCTGCGGCCCCAGCTGCGCGACGAGATCATCAAGTCCGCCCTGAGGCTTGCGCGCTGTGTGAATTACCGCAG
CCTTGGCACGTTCGAATTCCTGGTCGAGGAAACGGAATCGGGCGAGCAGAAGGACTTCGTCTTTATCGAAGCCAACCCGC
GCCTGCAGGTCGAACACACCATCACCGAGCAGGTCACCGGTGTCGACCTTGTCGCGCTGCAGATCGGCCTCGCGGCAGGG
CGCACGCTTGCCGATCTCGGGCTGGACCCGGCGTCGCCGCCGCAACCCAAGGGCTTTGCGATCCAGGTGCGCATCAACGC
GGAAAGTACCGATGCACAGGGGCTTGCGCGTCCCGCGTATGGCCGGCTCGAACGCTTCGATCCGCCGTCCGGTCCCGACG
TCCGCGTCGATTCCCACGGCTACACCGGCTATGAGCCGTCGCCCAACTTCGACACGCTGCTCGCCAAGCTGATCGTCAGC
AGCGCCGCACCAAAGTTCGAGGCCGCCGTGCGGCGCCTGCAGCGCAGCCTGGCGGAGTTCCGCATCGTCGGCGTGCCGAC
CAACATCAACCTGCTGCGCGCGCTGGTGCAGCGCGACGACTTCCTCACGCAGGATGTCCATACCCGCCACTTCGAGGCGA
TCCTGCCGGCGCTGGCGGCTTCGGCAGAGGCGGTCGCGGAAGCCGGCCGCGCGCAGGAGGCGCTGCTCGGCGATGCCTCT
CGCTCGCCCGCTGCACACGCGTCCAGATCGCATGAAGCCGAGGAAGAAGTCGAGGACGGCCTCGTGGCAATCCGTGCCCC
GCTGACCGGCCGCGTCGTGGAGATCGCCGTTGGTCTTGACGAGATCGTCAAGCCCGGACAGACCGTTGCCGTGCTCGATG
CCATGAAGATGGAACACGCGATCACCGCCGAATGCGGTGGCCGCGTGGTCGACCTGCGGCTGGAGAAGGGTGCGCTGGCA
GCGGAAGGCCAGATCCTGATCGTGGTGGAGCAGGTTGAGGCGGAGGGCGTGGCGGTGGATGCGGCGCAGAAGGCCGACCC
GAACGCCATCCGCGCGGATCTGCAGCGCGTGCTGGACCGGCACGCGTTTCTCGATGACGCCGCGCGTCCCGACGCCGTCG
CGCGGCGCCGCTCGCGTGGCCAGCGCACTGCGCGCGAGAATCTGGCCGACCTGTGCGATGCCGATACCTTCGTGGAATAT
GGCGGGCTGGCCCTTGCGGCGCAGTCGTCTCGCCGTACGAAGGACGATCTCATCGTCAACACGCCCGCGGACGGGCTGAT
CACCGGCATCGGCAACATCAACGGCGCACTGGTCGGCAAGGACCGTGCGCGCAGCGCGGTCATGGCCTACGACGCGACGG
TGCTCGCCGGGACGCAAGGCAAGCGCAACCATATCAAGACCGACCGTATCGTCGAAGTGGCGTTGCGCGATGAACTGCCG
CTGGTGCTGTTCGCCGAAGGCGGTGGCGGCCGGCCCGGAGATGTCGATTTCCCGTCTGTGTCAGGCCTCTACCAGCCGTC
CTTTGCCGCGTTCGCGGAACTGAGCGGCGAGGTGCCGGTGGTCGGCATCGTGTCGGGCCGCTGCTTTGCGGGCAATGCGG
CTTTCCTCGGCTGCTGCGACGTGATCATCGCCGACAAGTCGGCCAACATCGGCATGGCAGGGCCCGCGATGATCGAAGGG
GGCGGTCTCGGCATCTACCGCCCCGAAGAGGTCGGTCCCGCGCCCGTGCAGTTCGCCAATGGCGTGATCGACGTGCTGGT
AGAGAACGAGGCGGAAGCCGTGCAGGTCGCGAAGCACTACCTGTCCATGTTCCAGGGACGCGTCGAGCACTGGAGTGCGC
CGGACCCGCTGGCGCTGCGCCATGTCGTTCCTGAAAACCGTCTGCGCGTGTACGACACGCGCAAGGCCATAGAAGGCATT
GCCGATGCCGGCAGCGTGCTGATGCTGCGCGGCGGGTTTGGCGCGGGCATCCACACCGCGCTGGCGCGCGTGGAAGGGCA
GGCGGTTGGCATCATGGCCAACAACCCCTACCACCTCGGCGGCGCCATCGACGCCGATGCGGCCGACAAGGCATCGCGCT
TCATGCAGCTGTGCGATGCGCATGGGCTGCCGATCGTCTCGCTGATCGACACGCCGGGATTCATGGTCGGGCCGGAGTGC
GAAGCGCAAGCGCAGGTGCGGCACGTATCGCGCATGTTCCTCACAGCCGCGAAGCTGCGCGTCGCGCTGCTGGCCGTGAC
GCTGCGCAAGGGCTATGGGCTTGGCGCCATGGCGATGGCGGGCGGTGGCTTCCGCTCCGCGAGCTTCACTGTCTCGTGGC
CCACCGGCGAGTTCGGACCGATGGGTCTGGAAGGTGCCGTGAGACTGGGCTTCAAGAAGGAACTCGAAGCAGTGCCGGAT
GGCCCCGAGCGCAAGGCGCTGTTCGACCAGCTCGTCGGGCAGTCCTATGAGCGCGGGCATGCGATCAATACAGCAGCGGC
CGTGGAGATCGATGCCGTGATCGACCCGGCCCAGACCCGGAAATGGATCGCGCAGGGCATCGCCTCCGCCGAACTGCGAA
GCCGCCGCGCGCGCCGCGGCTTCGTCGATGCATGGTGA

Upstream 100 bases:

>100_bases
CATCAGCCGCTTCGGCATCCGTCCCTGAGCGGGCCGCAGCAACAAGCACGCAATACCAGTCACTGGCCGCAGAAGCCGCA
ATCTGAACGAGGAGACAAAA

Downstream 100 bases:

>100_bases
ACGCGACCGCAGCGATTCCATCCACAACAGCCAGGAGGTCTGCATGATCAGGAATGGTCCTGACCCGGCGCAGCTTGCAC
TGCGCGGGCTGCGCGTACTC

Product: pyruvate carboxylase., propionyl-CoA carboxylase

Products: NA

Alternate protein names: Pyruvic carboxylase; PYC [H]

Number of amino acids: Translated: 1105; Mature: 1105

Protein sequence:

>1105_residues
MNKLLIANRGEIALRVLRAARDLDIATVAVYSQDDASSRHRMLADEAIALDGSGPAAYIDIAGIITAAKASGCDAIHPGY
GFLSERADFAQACADAGIRFIGPTVEQLALFGDKGRALELAMESDVRVMPATRGGASLEDITSFFDKQGDAGVVIKAVGG
GGGRGMRVVRRREDLAEAYARCRSEAASAFGVDALYAERLVSRARHIEVQIAGDGTHVVALGERDCTLQRRFQKLVEIAP
SPVLRPQLRDEIIKSALRLARCVNYRSLGTFEFLVEETESGEQKDFVFIEANPRLQVEHTITEQVTGVDLVALQIGLAAG
RTLADLGLDPASPPQPKGFAIQVRINAESTDAQGLARPAYGRLERFDPPSGPDVRVDSHGYTGYEPSPNFDTLLAKLIVS
SAAPKFEAAVRRLQRSLAEFRIVGVPTNINLLRALVQRDDFLTQDVHTRHFEAILPALAASAEAVAEAGRAQEALLGDAS
RSPAAHASRSHEAEEEVEDGLVAIRAPLTGRVVEIAVGLDEIVKPGQTVAVLDAMKMEHAITAECGGRVVDLRLEKGALA
AEGQILIVVEQVEAEGVAVDAAQKADPNAIRADLQRVLDRHAFLDDAARPDAVARRRSRGQRTARENLADLCDADTFVEY
GGLALAAQSSRRTKDDLIVNTPADGLITGIGNINGALVGKDRARSAVMAYDATVLAGTQGKRNHIKTDRIVEVALRDELP
LVLFAEGGGGRPGDVDFPSVSGLYQPSFAAFAELSGEVPVVGIVSGRCFAGNAAFLGCCDVIIADKSANIGMAGPAMIEG
GGLGIYRPEEVGPAPVQFANGVIDVLVENEAEAVQVAKHYLSMFQGRVEHWSAPDPLALRHVVPENRLRVYDTRKAIEGI
ADAGSVLMLRGGFGAGIHTALARVEGQAVGIMANNPYHLGGAIDADAADKASRFMQLCDAHGLPIVSLIDTPGFMVGPEC
EAQAQVRHVSRMFLTAAKLRVALLAVTLRKGYGLGAMAMAGGGFRSASFTVSWPTGEFGPMGLEGAVRLGFKKELEAVPD
GPERKALFDQLVGQSYERGHAINTAAAVEIDAVIDPAQTRKWIAQGIASAELRSRRARRGFVDAW

Sequences:

>Translated_1105_residues
MNKLLIANRGEIALRVLRAARDLDIATVAVYSQDDASSRHRMLADEAIALDGSGPAAYIDIAGIITAAKASGCDAIHPGY
GFLSERADFAQACADAGIRFIGPTVEQLALFGDKGRALELAMESDVRVMPATRGGASLEDITSFFDKQGDAGVVIKAVGG
GGGRGMRVVRRREDLAEAYARCRSEAASAFGVDALYAERLVSRARHIEVQIAGDGTHVVALGERDCTLQRRFQKLVEIAP
SPVLRPQLRDEIIKSALRLARCVNYRSLGTFEFLVEETESGEQKDFVFIEANPRLQVEHTITEQVTGVDLVALQIGLAAG
RTLADLGLDPASPPQPKGFAIQVRINAESTDAQGLARPAYGRLERFDPPSGPDVRVDSHGYTGYEPSPNFDTLLAKLIVS
SAAPKFEAAVRRLQRSLAEFRIVGVPTNINLLRALVQRDDFLTQDVHTRHFEAILPALAASAEAVAEAGRAQEALLGDAS
RSPAAHASRSHEAEEEVEDGLVAIRAPLTGRVVEIAVGLDEIVKPGQTVAVLDAMKMEHAITAECGGRVVDLRLEKGALA
AEGQILIVVEQVEAEGVAVDAAQKADPNAIRADLQRVLDRHAFLDDAARPDAVARRRSRGQRTARENLADLCDADTFVEY
GGLALAAQSSRRTKDDLIVNTPADGLITGIGNINGALVGKDRARSAVMAYDATVLAGTQGKRNHIKTDRIVEVALRDELP
LVLFAEGGGGRPGDVDFPSVSGLYQPSFAAFAELSGEVPVVGIVSGRCFAGNAAFLGCCDVIIADKSANIGMAGPAMIEG
GGLGIYRPEEVGPAPVQFANGVIDVLVENEAEAVQVAKHYLSMFQGRVEHWSAPDPLALRHVVPENRLRVYDTRKAIEGI
ADAGSVLMLRGGFGAGIHTALARVEGQAVGIMANNPYHLGGAIDADAADKASRFMQLCDAHGLPIVSLIDTPGFMVGPEC
EAQAQVRHVSRMFLTAAKLRVALLAVTLRKGYGLGAMAMAGGGFRSASFTVSWPTGEFGPMGLEGAVRLGFKKELEAVPD
GPERKALFDQLVGQSYERGHAINTAAAVEIDAVIDPAQTRKWIAQGIASAELRSRRARRGFVDAW
>Mature_1105_residues
MNKLLIANRGEIALRVLRAARDLDIATVAVYSQDDASSRHRMLADEAIALDGSGPAAYIDIAGIITAAKASGCDAIHPGY
GFLSERADFAQACADAGIRFIGPTVEQLALFGDKGRALELAMESDVRVMPATRGGASLEDITSFFDKQGDAGVVIKAVGG
GGGRGMRVVRRREDLAEAYARCRSEAASAFGVDALYAERLVSRARHIEVQIAGDGTHVVALGERDCTLQRRFQKLVEIAP
SPVLRPQLRDEIIKSALRLARCVNYRSLGTFEFLVEETESGEQKDFVFIEANPRLQVEHTITEQVTGVDLVALQIGLAAG
RTLADLGLDPASPPQPKGFAIQVRINAESTDAQGLARPAYGRLERFDPPSGPDVRVDSHGYTGYEPSPNFDTLLAKLIVS
SAAPKFEAAVRRLQRSLAEFRIVGVPTNINLLRALVQRDDFLTQDVHTRHFEAILPALAASAEAVAEAGRAQEALLGDAS
RSPAAHASRSHEAEEEVEDGLVAIRAPLTGRVVEIAVGLDEIVKPGQTVAVLDAMKMEHAITAECGGRVVDLRLEKGALA
AEGQILIVVEQVEAEGVAVDAAQKADPNAIRADLQRVLDRHAFLDDAARPDAVARRRSRGQRTARENLADLCDADTFVEY
GGLALAAQSSRRTKDDLIVNTPADGLITGIGNINGALVGKDRARSAVMAYDATVLAGTQGKRNHIKTDRIVEVALRDELP
LVLFAEGGGGRPGDVDFPSVSGLYQPSFAAFAELSGEVPVVGIVSGRCFAGNAAFLGCCDVIIADKSANIGMAGPAMIEG
GGLGIYRPEEVGPAPVQFANGVIDVLVENEAEAVQVAKHYLSMFQGRVEHWSAPDPLALRHVVPENRLRVYDTRKAIEGI
ADAGSVLMLRGGFGAGIHTALARVEGQAVGIMANNPYHLGGAIDADAADKASRFMQLCDAHGLPIVSLIDTPGFMVGPEC
EAQAQVRHVSRMFLTAAKLRVALLAVTLRKGYGLGAMAMAGGGFRSASFTVSWPTGEFGPMGLEGAVRLGFKKELEAVPD
GPERKALFDQLVGQSYERGHAINTAAAVEIDAVIDPAQTRKWIAQGIASAELRSRRARRGFVDAW

Specific function: Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second, leading to oxaloacetate production. Fulfills an anaplerotic functi

COG id: COG4799

COG function: function code I; Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 carboxyltransferase domain [H]

Homologues:

Organism=Homo sapiens, GI106049528, Length=455, Percent_Identity=46.3736263736264, Blast_Score=338, Evalue=2e-92,
Organism=Homo sapiens, GI106049295, Length=455, Percent_Identity=46.3736263736264, Blast_Score=338, Evalue=2e-92,
Organism=Homo sapiens, GI106049292, Length=455, Percent_Identity=46.3736263736264, Blast_Score=338, Evalue=2e-92,
Organism=Homo sapiens, GI116805327, Length=479, Percent_Identity=38.4133611691023, Blast_Score=295, Evalue=1e-79,
Organism=Homo sapiens, GI295821183, Length=638, Percent_Identity=32.6018808777429, Blast_Score=276, Evalue=8e-74,
Organism=Homo sapiens, GI189095269, Length=466, Percent_Identity=37.9828326180258, Blast_Score=269, Evalue=1e-71,
Organism=Homo sapiens, GI65506442, Length=466, Percent_Identity=37.9828326180258, Blast_Score=269, Evalue=1e-71,
Organism=Homo sapiens, GI38679960, Length=432, Percent_Identity=28.9351851851852, Blast_Score=153, Evalue=1e-36,
Organism=Homo sapiens, GI38679974, Length=432, Percent_Identity=28.9351851851852, Blast_Score=153, Evalue=1e-36,
Organism=Homo sapiens, GI38679977, Length=432, Percent_Identity=28.9351851851852, Blast_Score=153, Evalue=1e-36,
Organism=Homo sapiens, GI38679967, Length=432, Percent_Identity=28.9351851851852, Blast_Score=153, Evalue=1e-36,
Organism=Homo sapiens, GI38679971, Length=432, Percent_Identity=28.9351851851852, Blast_Score=153, Evalue=1e-36,
Organism=Homo sapiens, GI134142062, Length=510, Percent_Identity=28.2352941176471, Blast_Score=152, Evalue=1e-36,
Organism=Homo sapiens, GI119943100, Length=441, Percent_Identity=25.8503401360544, Blast_Score=137, Evalue=5e-32,
Organism=Homo sapiens, GI295821216, Length=454, Percent_Identity=25.5506607929515, Blast_Score=130, Evalue=6e-30,
Organism=Homo sapiens, GI11545863, Length=413, Percent_Identity=27.1186440677966, Blast_Score=122, Evalue=3e-27,
Organism=Escherichia coli, GI1789654, Length=460, Percent_Identity=40.4347826086956, Blast_Score=292, Evalue=6e-80,
Organism=Caenorhabditis elegans, GI17562816, Length=452, Percent_Identity=46.4601769911504, Blast_Score=342, Evalue=5e-94,
Organism=Caenorhabditis elegans, GI17567343, Length=462, Percent_Identity=39.3939393939394, Blast_Score=286, Evalue=5e-77,
Organism=Caenorhabditis elegans, GI71987519, Length=476, Percent_Identity=38.2352941176471, Blast_Score=270, Evalue=2e-72,
Organism=Caenorhabditis elegans, GI17552936, Length=520, Percent_Identity=27.8846153846154, Blast_Score=162, Evalue=7e-40,
Organism=Caenorhabditis elegans, GI71997163, Length=512, Percent_Identity=27.5390625, Blast_Score=160, Evalue=3e-39,
Organism=Caenorhabditis elegans, GI71997168, Length=512, Percent_Identity=27.5390625, Blast_Score=160, Evalue=3e-39,
Organism=Caenorhabditis elegans, GI25147359, Length=506, Percent_Identity=26.6798418972332, Blast_Score=149, Evalue=6e-36,
Organism=Caenorhabditis elegans, GI25147362, Length=506, Percent_Identity=26.6798418972332, Blast_Score=149, Evalue=7e-36,
Organism=Caenorhabditis elegans, GI133931226, Length=361, Percent_Identity=30.1939058171745, Blast_Score=148, Evalue=1e-35,
Organism=Saccharomyces cerevisiae, GI6319695, Length=481, Percent_Identity=42.8274428274428, Blast_Score=315, Evalue=2e-86,
Organism=Saccharomyces cerevisiae, GI6321376, Length=481, Percent_Identity=43.035343035343, Blast_Score=300, Evalue=1e-81,
Organism=Saccharomyces cerevisiae, GI6319685, Length=459, Percent_Identity=37.2549019607843, Blast_Score=275, Evalue=3e-74,
Organism=Saccharomyces cerevisiae, GI6324343, Length=518, Percent_Identity=28.957528957529, Blast_Score=157, Evalue=7e-39,
Organism=Saccharomyces cerevisiae, GI6323863, Length=400, Percent_Identity=30.25, Blast_Score=157, Evalue=1e-38,
Organism=Drosophila melanogaster, GI281363050, Length=446, Percent_Identity=47.085201793722, Blast_Score=340, Evalue=2e-93,
Organism=Drosophila melanogaster, GI24652224, Length=446, Percent_Identity=47.085201793722, Blast_Score=340, Evalue=2e-93,
Organism=Drosophila melanogaster, GI24652222, Length=446, Percent_Identity=47.085201793722, Blast_Score=340, Evalue=2e-93,
Organism=Drosophila melanogaster, GI24652220, Length=446, Percent_Identity=47.085201793722, Blast_Score=340, Evalue=2e-93,
Organism=Drosophila melanogaster, GI24652218, Length=446, Percent_Identity=47.085201793722, Blast_Score=340, Evalue=2e-93,
Organism=Drosophila melanogaster, GI24652212, Length=446, Percent_Identity=47.085201793722, Blast_Score=340, Evalue=3e-93,
Organism=Drosophila melanogaster, GI24652210, Length=446, Percent_Identity=47.085201793722, Blast_Score=340, Evalue=3e-93,
Organism=Drosophila melanogaster, GI24652214, Length=446, Percent_Identity=47.085201793722, Blast_Score=340, Evalue=3e-93,
Organism=Drosophila melanogaster, GI19921944, Length=446, Percent_Identity=47.085201793722, Blast_Score=340, Evalue=3e-93,
Organism=Drosophila melanogaster, GI24652216, Length=446, Percent_Identity=47.085201793722, Blast_Score=340, Evalue=3e-93,
Organism=Drosophila melanogaster, GI24651757, Length=479, Percent_Identity=38.8308977035491, Blast_Score=278, Evalue=2e-74,
Organism=Drosophila melanogaster, GI24651759, Length=440, Percent_Identity=37.2727272727273, Blast_Score=236, Evalue=6e-62,
Organism=Drosophila melanogaster, GI161076409, Length=510, Percent_Identity=27.4509803921569, Blast_Score=155, Evalue=1e-37,
Organism=Drosophila melanogaster, GI24586458, Length=510, Percent_Identity=27.4509803921569, Blast_Score=155, Evalue=1e-37,
Organism=Drosophila melanogaster, GI161076407, Length=510, Percent_Identity=27.4509803921569, Blast_Score=155, Evalue=1e-37,
Organism=Drosophila melanogaster, GI24586460, Length=510, Percent_Identity=27.4509803921569, Blast_Score=155, Evalue=1e-37,
Organism=Drosophila melanogaster, GI24586065, Length=516, Percent_Identity=26.3565891472868, Blast_Score=127, Evalue=5e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR011761
- InterPro:   IPR013815
- InterPro:   IPR013816
- InterPro:   IPR011764
- InterPro:   IPR005482
- InterPro:   IPR000089
- InterPro:   IPR005479
- InterPro:   IPR005481
- InterPro:   IPR003379
- InterPro:   IPR013817
- InterPro:   IPR016185
- InterPro:   IPR000891
- InterPro:   IPR005930
- InterPro:   IPR011054
- InterPro:   IPR011053 [H]

Pfam domain/function: PF02785 Biotin_carb_C; PF00364 Biotin_lipoyl; PF00289 CPSase_L_chain; PF02786 CPSase_L_D2; PF00682 HMGL-like; PF02436 PYC_OADA [H]

EC number: =6.4.1.1 [H]

Molecular weight: Translated: 117590; Mature: 117590

Theoretical pI: Translated: 5.48; Mature: 5.48

Prosite motif: PS50975 ATP_GRASP ; PS00867 CPSASE_2 ; PS50979 BC ; PS50980 COA_CT_NTER ; PS50989 COA_CT_CTER ; PS50968 BIOTINYL_LIPOYL ; PS00188 BIOTIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNKLLIANRGEIALRVLRAARDLDIATVAVYSQDDASSRHRMLADEAIALDGSGPAAYID
CCCEEEECCCHHHHHHHHHHCCCCEEEEEEEECCCCCHHHHHHHCCEEEECCCCCEEEEE
IAGIITAAKASGCDAIHPGYGFLSERADFAQACADAGIRFIGPTVEQLALFGDKGRALEL
HHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCEEECCCHHHHHHCCCCCCEEEE
AMESDVRVMPATRGGASLEDITSFFDKQGDAGVVIKAVGGGGGRGMRVVRRREDLAEAYA
EECCCCEEEECCCCCCCHHHHHHHHHCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHH
RCRSEAASAFGVDALYAERLVSRARHIEVQIAGDGTHVVALGERDCTLQRRFQKLVEIAP
HHHHHHHHHCCHHHHHHHHHHHHHHEEEEEEECCCEEEEEECCCCCHHHHHHHHHHHHCC
SPVLRPQLRDEIIKSALRLARCVNYRSLGTFEFLVEETESGEQKDFVFIEANPRLQVEHT
CCCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCCCCEEEEECCCCEEEEEE
ITEQVTGVDLVALQIGLAAGRTLADLGLDPASPPQPKGFAIQVRINAESTDAQGLARPAY
HHHHHCCCEEEEEHHHHHCCCCHHHCCCCCCCCCCCCCEEEEEEEECCCCCCCCCCCCCH
GRLERFDPPSGPDVRVDSHGYTGYEPSPNFDTLLAKLIVSSAAPKFEAAVRRLQRSLAEF
HHHHCCCCCCCCCEEECCCCCCCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHE
RIVGVPTNINLLRALVQRDDFLTQDVHTRHFEAILPALAASAEAVAEAGRAQEALLGDAS
EEEECCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCCC
RSPAAHASRSHEAEEEVEDGLVAIRAPLTGRVVEIAVGLDEIVKPGQTVAVLDAMKMEHA
CCCCHHCCCCCCHHHHHHCCEEEEECCCCCCEEEEEECHHHHHCCCCEEEHHHHHHHHHH
ITAECGGRVVDLRLEKGALAAEGQILIVVEQVEAEGVAVDAAQKADPNAIRADLQRVLDR
HHHHCCCEEEEEEEECCCEECCCEEEEEEEEECCCCEEEECCCCCCCHHHHHHHHHHHHH
HAFLDDAARPDAVARRRSRGQRTARENLADLCDADTFVEYGGLALAAQSSRRTKDDLIVN
HHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCEEEEECCCCCCCCCEEEE
TPADGLITGIGNINGALVGKDRARSAVMAYDATVLAGTQGKRNHIKTDRIVEVALRDELP
CCCCCEEEECCCCCCEEEECHHHHHEEEEECEEEEECCCCCCCCCCCCCEEEEEECCCCC
LVLFAEGGGGRPGDVDFPSVSGLYQPSFAAFAELSGEVPVVGIVSGRCFAGNAAFLGCCD
EEEEECCCCCCCCCCCCCCCCCCCCCCHHHHHHCCCCCCEEEEECCCEEECCCHHEEEEE
VIIADKSANIGMAGPAMIEGGGLGIYRPEEVGPAPVQFANGVIDVLVENEAEAVQVAKHY
EEEECCCCCCCCCCCCEEECCCCCCCCCCCCCCCCHHHHCCEEEEEECCCHHHHHHHHHH
LSMFQGRVEHWSAPDPLALRHVVPENRLRVYDTRKAIEGIADAGSVLMLRGGFGAGIHTA
HHHHHHHHHCCCCCCCCHHHHCCCCCCEEEEEHHHHHHHHCCCCCEEEEECCCCCHHHHH
LARVEGQAVGIMANNPYHLGGAIDADAADKASRFMQLCDAHGLPIVSLIDTPGFMVGPEC
HHHHCCCEEEEEECCCEEECCCCCCCHHHHHHHHHHHHHCCCCCEEEEECCCCCEECCCC
EAQAQVRHVSRMFLTAAKLRVALLAVTLRKGYGLGAMAMAGGGFRSASFTVSWPTGEFGP
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHCCCCCCCCEEEEECCCCCCCC
MGLEGAVRLGFKKELEAVPDGPERKALFDQLVGQSYERGHAINTAAAVEIDAVIDPAQTR
CCCCHHEECCCHHHHHCCCCCCHHHHHHHHHHCCCHHCCCCCCCEEEEEEEEECCCHHHH
KWIAQGIASAELRSRRARRGFVDAW
HHHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MNKLLIANRGEIALRVLRAARDLDIATVAVYSQDDASSRHRMLADEAIALDGSGPAAYID
CCCEEEECCCHHHHHHHHHHCCCCEEEEEEEECCCCCHHHHHHHCCEEEECCCCCEEEEE
IAGIITAAKASGCDAIHPGYGFLSERADFAQACADAGIRFIGPTVEQLALFGDKGRALEL
HHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCEEECCCHHHHHHCCCCCCEEEE
AMESDVRVMPATRGGASLEDITSFFDKQGDAGVVIKAVGGGGGRGMRVVRRREDLAEAYA
EECCCCEEEECCCCCCCHHHHHHHHHCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHH
RCRSEAASAFGVDALYAERLVSRARHIEVQIAGDGTHVVALGERDCTLQRRFQKLVEIAP
HHHHHHHHHCCHHHHHHHHHHHHHHEEEEEEECCCEEEEEECCCCCHHHHHHHHHHHHCC
SPVLRPQLRDEIIKSALRLARCVNYRSLGTFEFLVEETESGEQKDFVFIEANPRLQVEHT
CCCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCCCCEEEEECCCCEEEEEE
ITEQVTGVDLVALQIGLAAGRTLADLGLDPASPPQPKGFAIQVRINAESTDAQGLARPAY
HHHHHCCCEEEEEHHHHHCCCCHHHCCCCCCCCCCCCCEEEEEEEECCCCCCCCCCCCCH
GRLERFDPPSGPDVRVDSHGYTGYEPSPNFDTLLAKLIVSSAAPKFEAAVRRLQRSLAEF
HHHHCCCCCCCCCEEECCCCCCCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHE
RIVGVPTNINLLRALVQRDDFLTQDVHTRHFEAILPALAASAEAVAEAGRAQEALLGDAS
EEEECCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCCC
RSPAAHASRSHEAEEEVEDGLVAIRAPLTGRVVEIAVGLDEIVKPGQTVAVLDAMKMEHA
CCCCHHCCCCCCHHHHHHCCEEEEECCCCCCEEEEEECHHHHHCCCCEEEHHHHHHHHHH
ITAECGGRVVDLRLEKGALAAEGQILIVVEQVEAEGVAVDAAQKADPNAIRADLQRVLDR
HHHHCCCEEEEEEEECCCEECCCEEEEEEEEECCCCEEEECCCCCCCHHHHHHHHHHHHH
HAFLDDAARPDAVARRRSRGQRTARENLADLCDADTFVEYGGLALAAQSSRRTKDDLIVN
HHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCEEEEECCCCCCCCCEEEE
TPADGLITGIGNINGALVGKDRARSAVMAYDATVLAGTQGKRNHIKTDRIVEVALRDELP
CCCCCEEEECCCCCCEEEECHHHHHEEEEECEEEEECCCCCCCCCCCCCEEEEEECCCCC
LVLFAEGGGGRPGDVDFPSVSGLYQPSFAAFAELSGEVPVVGIVSGRCFAGNAAFLGCCD
EEEEECCCCCCCCCCCCCCCCCCCCCCHHHHHHCCCCCCEEEEECCCEEECCCHHEEEEE
VIIADKSANIGMAGPAMIEGGGLGIYRPEEVGPAPVQFANGVIDVLVENEAEAVQVAKHY
EEEECCCCCCCCCCCCEEECCCCCCCCCCCCCCCCHHHHCCEEEEEECCCHHHHHHHHHH
LSMFQGRVEHWSAPDPLALRHVVPENRLRVYDTRKAIEGIADAGSVLMLRGGFGAGIHTA
HHHHHHHHHCCCCCCCCHHHHCCCCCCEEEEEHHHHHHHHCCCCCEEEEECCCCCHHHHH
LARVEGQAVGIMANNPYHLGGAIDADAADKASRFMQLCDAHGLPIVSLIDTPGFMVGPEC
HHHHCCCEEEEEECCCEEECCCCCCCHHHHHHHHHHHHHCCCCCEEEEECCCCCEECCCC
EAQAQVRHVSRMFLTAAKLRVALLAVTLRKGYGLGAMAMAGGGFRSASFTVSWPTGEFGP
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHCCCCCCCCEEEEECCCCCCCC
MGLEGAVRLGFKKELEAVPDGPERKALFDQLVGQSYERGHAINTAAAVEIDAVIDPAQTR
CCCCHHEECCCHHHHHCCCCCCHHHHHHHHHHCCCHHCCCCCCCEEEEEEEEECCCHHHH
KWIAQGIASAELRSRRARRGFVDAW
HHHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]